A citation-based method for searching scientific literature

Sergi Aranda, Ariadna Laguna, Susana de la Luna. FASEB J 2011
Times Cited: 196







List of co-cited articles
910 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs.
Pamela A Lochhead, Gary Sibbet, Nick Morrice, Vaughn Cleghon. Cell 2005
214
29

Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A.
Yasushi Ogawa, Yosuke Nonaka, Toshiyasu Goto, Eriko Ohnishi, Toshiyuki Hiramatsu, Isao Kii, Miyo Yoshida, Teikichi Ikura, Hiroshi Onogi, Hiroshi Shibuya,[...]. Nat Commun 2010
178
22

Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition.
Meera Soundararajan, Annette K Roos, Pavel Savitsky, Panagis Filippakopoulos, Arminja N Kettenbach, Jesper V Olsen, Scott A Gerber, Jeyanthy Eswaran, Stefan Knapp, Jonathan M Elkins. Structure 2013
97
21


The protein kinase complement of the human genome.
G Manning, D B Whyte, R Martinez, T Hunter, S Sudarsanam. Science 2002
20

Inhibition of DYRK1A destabilizes EGFR and reduces EGFR-dependent glioblastoma growth.
Natividad Pozo, Cristina Zahonero, Paloma Fernández, Jose M Liñares, Angel Ayuso, Masatoshi Hagiwara, Angel Pérez, Jose R Ricoy, Aurelio Hernández-Laín, Juan M Sepúlveda,[...]. J Clin Invest 2013
86
20

The role of DYRK1A in neurodegenerative diseases.
Jerzy Wegiel, Cheng-Xin Gong, Yu-Wen Hwang. FEBS J 2011
166
17


Activation, regulation, and inhibition of DYRK1A.
Walter Becker, Wolfgang Sippl. FEBS J 2011
140
17

DYRK1A in neurodegeneration and cancer: Molecular basis and clinical implications.
Ramzi Abbassi, Terrance G Johns, Michael Kassiou, Lenka Munoz. Pharmacol Ther 2015
96
16

DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly.
Larisa Litovchick, Laurence A Florens, Selene K Swanson, Michael P Washburn, James A DeCaprio. Genes Dev 2011
176
16

Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation.
Nora Göckler, Guillermo Jofre, Chrisovalantis Papadopoulos, Ulf Soppa, Francisco J Tejedor, Walter Becker. FEBS J 2009
166
16

Chromatin-wide profiling of DYRK1A reveals a role as a gene-specific RNA polymerase II CTD kinase.
Chiara Di Vona, Daniela Bezdan, Abul B M M K Islam, Eulàlia Salichs, Nuria López-Bigas, Stephan Ossowski, Susana de la Luna. Mol Cell 2015
68
23

DYRK protein kinases.
Ulf Soppa, Walter Becker. Curr Biol 2015
31
48

DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage.
Naoe Taira, Keishi Nihira, Tomoko Yamaguchi, Yoshio Miki, Kiyotsugu Yoshida. Mol Cell 2007
210
14


Specificity determinants of substrate recognition by the protein kinase DYRK1A.
S Himpel, W Tegge, R Frank, S Leder, H G Joost, W Becker. J Biol Chem 2000
181
14

Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B.
Tania Tahtouh, Jonathan M Elkins, Panagis Filippakopoulos, Meera Soundararajan, Guillaume Burgy, Emilie Durieu, Claude Cochet, Ralf S Schmid, Donald C Lo, Florent Delhommel,[...]. J Med Chem 2012
138
14

minibrain: a new protein kinase family involved in postembryonic neurogenesis in Drosophila.
F Tejedor, X R Zhu, E Kaltenbach, A Ackermann, A Baumann, I Canal, M Heisenberg, K F Fischbach, O Pongs. Neuron 1995
299
13

DYRK1A: the double-edged kinase as a protagonist in cell growth and tumorigenesis.
P Fernández-Martínez, C Zahonero, P Sánchez-Gómez. Mol Cell Oncol 2015
60
21

DYRK1A modulates c-MET in pancreatic ductal adenocarcinoma to drive tumour growth.
Jeroni Luna, Jacopo Boni, Miriam Cuatrecasas, Xavier Bofill-De Ros, Estela Núñez-Manchón, Meritxell Gironella, Eva C Vaquero, Maria L Arbones, Susana de la Luna, Cristina Fillat. Gut 2019
35
37

Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) Inhibitors as Potential Therapeutics.
Dnyandev B Jarhad, Karishma K Mashelkar, Hong-Rae Kim, Minsoo Noh, Lak Shin Jeong. J Med Chem 2018
50
26

DYRK2 priming phosphorylation of c-Jun and c-Myc modulates cell cycle progression in human cancer cells.
Naoe Taira, Rei Mimoto, Morito Kurata, Tomoko Yamaguchi, Masanobu Kitagawa, Yoshio Miki, Kiyotsugu Yoshida. J Clin Invest 2012
94
12

Dyrk1A haploinsufficiency affects viability and causes developmental delay and abnormal brain morphology in mice.
Vassiliki Fotaki, Mara Dierssen, Soledad Alcántara, Salvador Martínez, Eulàlia Martí, Caty Casas, Joana Visa, Eduardo Soriano, Xavier Estivill, Maria L Arbonés. Mol Cell Biol 2002
238
12

The Down syndrome-related protein kinase DYRK1A phosphorylates p27(Kip1) and Cyclin D1 and induces cell cycle exit and neuronal differentiation.
Ulf Soppa, Julian Schumacher, Victoria Florencio Ortiz, Tobias Pasqualon, Francisco J Tejedor, Walter Becker. Cell Cycle 2014
101
12


Dyrk, a dual specificity protein kinase with unique structural features whose activity is dependent on tyrosine residues between subdomains VII and VIII.
H Kentrup, W Becker, J Heukelbach, A Wilmes, A Schürmann, C Huppertz, H Kainulainen, H G Joost. J Biol Chem 1996
206
12

Disruptive de novo mutations of DYRK1A lead to a syndromic form of autism and ID.
B W M van Bon, B P Coe, R Bernier, C Green, J Gerdts, K Witherspoon, T Kleefstra, M H Willemsen, R Kumar, P Bosco,[...]. Mol Psychiatry 2016
96
12

MNB/DYRK1A as a multiple regulator of neuronal development.
Francisco J Tejedor, Barbara Hämmerle. FEBS J 2011
146
12

DYRK1A haploinsufficiency causes a new recognizable syndrome with microcephaly, intellectual disability, speech impairment, and distinct facies.
Jianling Ji, Hane Lee, Bob Argiropoulos, Naghmeh Dorrani, John Mann, Julian A Martinez-Agosto, Natalia Gomez-Ospina, Natalie Gallant, Jonathan A Bernstein, Louanne Hudgins,[...]. Eur J Hum Genet 2015
67
17

A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.
Peng Wang, Juan-Carlos Alvarez-Perez, Dan P Felsenfeld, Hongtao Liu, Sharmila Sivendran, Aaron Bender, Anil Kumar, Roberto Sanchez, Donald K Scott, Adolfo Garcia-Ocaña,[...]. Nat Med 2015
228
12

A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT.
Yousang Gwack, Sonia Sharma, Julie Nardone, Bogdan Tanasa, Alina Iuga, Sonal Srikanth, Heidi Okamura, Diana Bolton, Stefan Feske, Patrick G Hogan,[...]. Nature 2006
288
12

DYRK1A inhibition and cognitive rescue in a Down syndrome mouse model are induced by new fluoro-DANDY derivatives.
Fernanda Neumann, Stéphanie Gourdain, Christelle Albac, Alain D Dekker, Linh Chi Bui, Julien Dairou, Isabelle Schmitz-Afonso, Nathalie Hue, Fernando Rodrigues-Lima, Jean M Delabar,[...]. Sci Rep 2018
32
37


DYRK1A-mediated hyperphosphorylation of Tau. A functional link between Down syndrome and Alzheimer disease.
Soo-Ryoon Ryoo, Hey Kyeong Jeong, Chinzorig Radnaabazar, Jin-Ju Yoo, Hyun-Jeong Cho, Hye-Won Lee, In-Sook Kim, Young-Hee Cheon, Young Soo Ahn, Sul-Hee Chung,[...]. J Biol Chem 2007
171
12

The DYRK Family of Kinases in Cancer: Molecular Functions and Therapeutic Opportunities.
Jacopo Boni, Carlota Rubio-Perez, Nuria López-Bigas, Cristina Fillat, Susana de la Luna. Cancers (Basel) 2020
27
44


DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1.
Xiumei Guo, Jason G Williams, Thaddeus T Schug, Xiaoling Li. J Biol Chem 2010
167
11

10-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acids are selective inhibitors of DYRK1A.
Hannes Falke, Apirat Chaikuad, Anja Becker, Nadège Loaëc, Olivier Lozach, Samira Abu Jhaisha, Walter Becker, Peter G Jones, Lutz Preu, Knut Baumann,[...]. J Med Chem 2015
57
19

Selective inhibition of the kinase DYRK1A by targeting its folding process.
Isao Kii, Yuto Sumida, Toshiyasu Goto, Rie Sonamoto, Yukiko Okuno, Suguru Yoshida, Tomoe Kato-Sumida, Yuka Koike, Minako Abe, Yosuke Nonaka,[...]. Nat Commun 2016
49
22

Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling.
Frank Wippich, Bernd Bodenmiller, Maria Gustafsson Trajkovska, Stefanie Wanka, Ruedi Aebersold, Lucas Pelkmans. Cell 2013
359
11


Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A.
S Himpel, P Panzer, K Eirmbter, H Czajkowska, M Sayed, L C Packman, T Blundell, H Kentrup, J Grötzinger, H G Joost,[...]. Biochem J 2001
123
11

Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome.
X Altafaj, M Dierssen, C Baamonde, E Martí, J Visa, J Guimerà, M Oset, J R González, J Flórez, C Fillat,[...]. Hum Mol Genet 2001
291
11

Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors: a survey of recent patent literature.
Thu Lan Nguyen, Corinne Fruit, Yann Hérault, Laurent Meijer, Thierry Besson. Expert Opin Ther Pat 2017
35
31


Inhibition of DYRK1A Stimulates Human β-Cell Proliferation.
Ercument Dirice, Deepika Walpita, Amedeo Vetere, Bennett C Meier, Sevim Kahraman, Jiang Hu, Vlado Dančík, Sean M Burns, Tamara J Gilbert, David E Olson,[...]. Diabetes 2016
114
11

The selectivity of protein kinase inhibitors: a further update.
Jenny Bain, Lorna Plater, Matt Elliott, Natalia Shpiro, C James Hastie, Hilary McLauchlan, Iva Klevernic, J Simon C Arthur, Dario R Alessi, Philip Cohen. Biochem J 2007
10

Ten new cases further delineate the syndromic intellectual disability phenotype caused by mutations in DYRK1A.
Lucas M Bronicki, Claire Redin, Severine Drunat, Amélie Piton, Michael Lyons, Sandrine Passemard, Clarisse Baumann, Laurence Faivre, Julien Thevenon, Jean-Baptiste Rivière,[...]. Eur J Hum Genet 2015
41
24

DYRK1A: a master regulatory protein controlling brain growth.
Fayçal Guedj, Patricia Lopes Pereira, Sonia Najas, Maria-Jose Barallobre, Caroline Chabert, Benoit Souchet, Catherine Sebrie, Catherine Verney, Yann Herault, Mariona Arbones,[...]. Neurobiol Dis 2012
94
10


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.