A citation-based method for searching scientific literature

Krzysztof Łabuzek, Dariusz Suchy, Bożena Gabryel, Anna Bielecka, Sebastian Liber, Bogusław Okopień. Pharmacol Rep 2010
Times Cited: 221







List of co-cited articles
690 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Role of AMP-activated protein kinase in mechanism of metformin action.
G Zhou, R Myers, Y Li, Y Chen, X Shen, J Fenyk-Melody, M Wu, J Ventre, T Doebber, N Fujii,[...]. J Clin Invest 2001
19

Metformin activates an atypical PKC-CBP pathway to promote neurogenesis and enhance spatial memory formation.
Jing Wang, Denis Gallagher, Loren M DeVito, Gonzalo I Cancino, David Tsui, Ling He, Gordon M Keller, Paul W Frankland, David R Kaplan, Freda D Miller. Cell Stem Cell 2012
284
17

Metformin: from mechanisms of action to therapies.
Marc Foretz, Bruno Guigas, Luc Bertrand, Michael Pollak, Benoit Viollet. Cell Metab 2014
661
15

Metformin improves healthspan and lifespan in mice.
Alejandro Martin-Montalvo, Evi M Mercken, Sarah J Mitchell, Hector H Palacios, Patricia L Mote, Morten Scheibye-Knudsen, Ana P Gomes, Theresa M Ward, Robin K Minor, Marie-José Blouin,[...]. Nat Commun 2013
733
15

Long-term metformin usage and cognitive function among older adults with diabetes.
Tze Pin Ng, Liang Feng, Keng Bee Yap, Tih Shih Lee, Chay Hoon Tan, Bengt Winblad. J Alzheimers Dis 2014
179
14

The mechanisms of action of metformin.
Graham Rena, D Grahame Hardie, Ewan R Pearson. Diabetologia 2017
751
13

Metformin treatment prevents amyloid plaque deposition and memory impairment in APP/PS1 mice.
Zhenri Ou, Xuejian Kong, Xiangdong Sun, Xiaosong He, Le Zhang, Zhuo Gong, Jingyi Huang, Biao Xu, Dahong Long, Jianhua Li,[...]. Brain Behav Immun 2018
139
13


Metformin - a Future Therapy for Neurodegenerative Diseases : Theme: Drug Discovery, Development and Delivery in Alzheimer's Disease Guest Editor: Davide Brambilla.
Magdalena Markowicz-Piasecka, Joanna Sikora, Aleksandra Szydłowska, Agata Skupień, Elżbieta Mikiciuk-Olasik, Kristiina M Huttunen. Pharm Res 2017
121
12

Metformin inhibits adenosine 5'-monophosphate-activated kinase activation and prevents increases in neuropeptide Y expression in cultured hypothalamic neurons.
Catherine Chau-Van, Marcella Gamba, Roberto Salvi, Rolf C Gaillard, François P Pralong. Endocrinology 2007
78
15

Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis.
Narender Nath, Musfiquidin Khan, Manjeet K Paintlia, Inderjit Singh, Md Nasrul Hoda, Shailendra Giri. J Immunol 2009
245
11

Metformin attenuates Alzheimer's disease-like neuropathology in obese, leptin-resistant mice.
Jiejie Li, Jiao Deng, Wenli Sheng, Zhiyi Zuo. Pharmacol Biochem Behav 2012
171
11

Metformin decreases GnRH- and activin-induced gonadotropin secretion in rat pituitary cells: potential involvement of adenosine 5' monophosphate-activated protein kinase (PRKA).
Lucie Tosca, Pascal Froment, Christelle Rame, J R McNeilly, A S McNeilly, Virginie Maillard, Joelle Dupont. Biol Reprod 2011
45
24

The Effect of Metformin on Serum Gonadotropin Levels in Postmenopausal Women with Diabetes and Prediabetes: A Pilot Study.
Robert Krysiak, Witold Szkróbka, Bogusław Okopień. Exp Clin Endocrinol Diabetes 2018
15
73

Metformin lowers α-synuclein phosphorylation and upregulates neurotrophic factor in the MPTP mouse model of Parkinson's disease.
Nikita Katila, Sunil Bhurtel, Sina Shadfar, Sunil Srivastav, Sabita Neupane, Uttam Ojha, Gil-Saeng Jeong, Dong-Young Choi. Neuropharmacology 2017
72
15


Effects of metformin on learning and memory behaviors and brain mitochondrial functions in high fat diet induced insulin resistant rats.
Hiranya Pintana, Nattayaporn Apaijai, Wasana Pratchayasakul, Nipon Chattipakorn, Siriporn C Chattipakorn. Life Sci 2012
153
10


TSH-lowering effect of metformin in type 2 diabetic patients: differences between euthyroid, untreated hypothyroid, and euthyroid on L-T4 therapy patients.
Carlo Cappelli, Mario Rotondi, Ilenia Pirola, Barbara Agosti, Elena Gandossi, Umberto Valentini, Elvira De Martino, Antonio Cimino, Luca Chiovato, Enrico Agabiti-Rosei,[...]. Diabetes Care 2009
97
10

Clinical pharmacokinetics of metformin.
Garry G Graham, Jeroen Punt, Manit Arora, Richard O Day, Matthew P Doogue, Janna K Duong, Timothy J Furlong, Jerry R Greenfield, Louise C Greenup, Carl M Kirkpatrick,[...]. Clin Pharmacokinet 2011
628
10

Neuroprotective effect of metformin in MPTP-induced Parkinson's disease in mice.
S P Patil, P D Jain, P J Ghumatkar, R Tambe, S Sathaye. Neuroscience 2014
150
10

Incidence of dementia is increased in type 2 diabetes and reduced by the use of sulfonylureas and metformin.
Chih-Cheng Hsu, Mark L Wahlqvist, Meei-Shyuan Lee, Hsin-Ni Tsai. J Alzheimers Dis 2011
226
10

The effect of metformin on prolactin levels in patients with drug-induced hyperprolactinemia.
Robert Krysiak, Karolina Kowalcze, Witold Szkrobka, Boguslaw Okopien. Eur J Intern Med 2016
23
43

Sex-Dependent Effect of Metformin on Serum Prolactin Levels In Hyperprolactinemic Patients With Type 2 Diabetes: A Pilot Study.
Robert Krysiak, Witold Szkróbka, Bogusław Okopień. Exp Clin Endocrinol Diabetes 2018
16
62

Cellular and molecular mechanisms of metformin: an overview.
Benoit Viollet, Bruno Guigas, Nieves Sanz Garcia, Jocelyne Leclerc, Marc Foretz, Fabrizio Andreelli. Clin Sci (Lond) 2012
10

Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling.
Eva Kickstein, Sybille Krauss, Paul Thornhill, Désirée Rutschow, Raphael Zeller, John Sharkey, Ritchie Williamson, Melanie Fuchs, Andrea Köhler, Hartmut Glossmann,[...]. Proc Natl Acad Sci U S A 2010
279
10

Effects of the Insulin Sensitizer Metformin in Alzheimer Disease: Pilot Data From a Randomized Placebo-controlled Crossover Study.
Aaron M Koenig, Dawn Mechanic-Hamilton, Sharon X Xie, Martha F Combs, Anne R Cappola, Long Xie, John A Detre, David A Wolk, Steven E Arnold. Alzheimer Dis Assoc Disord 2017
134
9

Metformin may produce antidepressant effects through improvement of cognitive function among depressed patients with diabetes mellitus.
Min Guo, Jia Mi, Qiu-Ming Jiang, Jin-Mei Xu, Ying-Ying Tang, Geng Tian, Bin Wang. Clin Exp Pharmacol Physiol 2014
111
9

The Therapeutic Potential of Metformin in Neurodegenerative Diseases.
Carola Rotermund, Gerrit Machetanz, Julia C Fitzgerald. Front Endocrinol (Lausanne) 2018
124
9

Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response.
Julie Sesen, Perrine Dahan, Sarah J Scotland, Estelle Saland, Van-Thi Dang, Anthony Lemarié, Betty M Tyler, Henry Brem, Christine Toulas, Elizabeth Cohen-Jonathan Moyal,[...]. PLoS One 2015
112
9

Metformin, other antidiabetic drugs, and risk of Alzheimer's disease: a population-based case-control study.
Patrick Imfeld, Michael Bodmer, Susan S Jick, Christoph R Meier. J Am Geriatr Soc 2012
220
9



Metformin-inclusive sulfonylurea therapy reduces the risk of Parkinson's disease occurring with Type 2 diabetes in a Taiwanese population cohort.
Mark L Wahlqvist, Meei-Shyuan Lee, Chih-Cheng Hsu, Shao-Yuan Chuang, Jiunn-Tay Lee, Hsin-Ni Tsai. Parkinsonism Relat Disord 2012
137
9

Metformin Use Associated with Reduced Risk of Dementia in Patients with Diabetes: A Systematic Review and Meta-Analysis.
Jared M Campbell, Matthew D Stephenson, Barbora de Courten, Ian Chapman, Susan M Bellman, Edoardo Aromataris. J Alzheimers Dis 2018
83
10

Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase.
Anila K Madiraju, Derek M Erion, Yasmeen Rahimi, Xian-Man Zhang, Demetrios T Braddock, Ronald A Albright, Brett J Prigaro, John L Wood, Sanjay Bhanot, Michael J MacDonald,[...]. Nature 2014
708
8

The effect of metformin on food intake and its potential role in hypothalamic regulation in obese diabetic rats.
Wen-Shan Lv, Jun-Ping Wen, Li Li, Rui-Xia Sun, Jing Wang, Yu-Xin Xian, Cai-Xia Cao, Yun-Long Wang, Yan-Yan Gao. Brain Res 2012
73
10

Metformin therapy in a transgenic mouse model of Huntington's disease.
Thong C Ma, Jessica L Buescher, Benjamin Oatis, Jason A Funk, Andrew J Nash, Raeann L Carrier, Kari R Hoyt. Neurosci Lett 2007
165
8

Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.
M Y El-Mir, V Nogueira, E Fontaine, N Avéret, M Rigoulet, X Leverve. J Biol Chem 2000
955
8

Metformin as a Tool to Target Aging.
Nir Barzilai, Jill P Crandall, Stephen B Kritchevsky, Mark A Espeland. Cell Metab 2016
464
8

Acute metformin preconditioning confers neuroprotection against focal cerebral ischaemia by pre-activation of AMPK-dependent autophagy.
Teng Jiang, Jin-Tai Yu, Xi-Chen Zhu, Hui-Fu Wang, Meng-Shan Tan, Lei Cao, Qiao-Quan Zhang, Li Gao, Jian-Quan Shi, Ying-Dong Zhang,[...]. Br J Pharmacol 2014
172
8

Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription.
Yaomin Chen, Kun Zhou, Ruishan Wang, Yun Liu, Young-Don Kwak, Tao Ma, Robert C Thompson, Yongbo Zhao, Layton Smith, Laura Gasparini,[...]. Proc Natl Acad Sci U S A 2009
284
8

Metformin induces up-regulation of blood-brain barrier functions by activating AMP-activated protein kinase in rat brain microvascular endothelial cells.
Fuyuko Takata, Shinya Dohgu, Junichi Matsumoto, Takashi Machida, Shuji Kaneshima, Mai Matsuo, Shinya Sakaguchi, Yuki Takeshige, Atsushi Yamauchi, Yasufumi Kataoka. Biochem Biophys Res Commun 2013
46
15

Insulin sensitizing drugs increase the endogenous dopaminergic tone in obese insulin-resistant women with polycystic ovary syndrome.
C Ortega-González, L Cardoza, B Coutiño, R Hidalgo, G Arteaga-Troncoso, A Parra. J Endocrinol 2005
40
17

Antidiabetic drugs restore abnormal transport of amyloid-β across the blood-brain barrier and memory impairment in db/db mice.
Fang Chen, Rong Rong Dong, Kai Long Zhong, Arijit Ghosh, Su Su Tang, Yan Long, Mei Hu, Ming Xing Miao, Jian Min Liao, Hong Bing Sun,[...]. Neuropharmacology 2016
84
8

Metformin Activates AMPK through the Lysosomal Pathway.
Chen-Song Zhang, Mengqi Li, Teng Ma, Yue Zong, Jiwen Cui, Jin-Wei Feng, Yu-Qing Wu, Shu-Yong Lin, Sheng-Cai Lin. Cell Metab 2016
122
7

Metformin attenuates blood-brain barrier disruption in mice following middle cerebral artery occlusion.
Yanqun Liu, Guanghui Tang, Yaning Li, Yang Wang, Xiaoyan Chen, Xiang Gu, Zhijun Zhang, Yongting Wang, Guo-Yuan Yang. J Neuroinflammation 2014
112
7

Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner.
Adem Kalender, Anand Selvaraj, So Young Kim, Pawan Gulati, Sophie Brûlé, Benoit Viollet, Bruce E Kemp, Nabeel Bardeesy, Patrick Dennis, John J Schlager,[...]. Cell Metab 2010
587
7

Metformin - a new old drug.
Marta Patrycja Wróbel, Bogdan Marek, Dariusz Kajdaniuk, Dominika Rokicka, Aleksandra Szymborska-Kajanek, Krzysztof Strojek. Endokrynol Pol 2017
36
19



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.