A citation-based method for searching scientific literature

Rongbin Zhou, Amir S Yazdi, Philippe Menu, Jürg Tschopp. Nature 2011
Times Cited: 3005







List of co-cited articles
701 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome.
Kiichi Nakahira, Jeffrey Adam Haspel, Vijay A K Rathinam, Seon-Jin Lee, Tamas Dolinay, Hilaire C Lam, Joshua A Englert, Marlene Rabinovitch, Manuela Cernadas, Hong Pyo Kim,[...]. Nat Immunol 2011
23

The inflammasomes.
Kate Schroder, Jurg Tschopp. Cell 2010
19

Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
Kenichi Shimada, Timothy R Crother, Justin Karlin, Jargalsaikhan Dagvadorj, Norika Chiba, Shuang Chen, V Krishnan Ramanujan, Andrea J Wolf, Laurent Vergnes, David M Ojcius,[...]. Immunity 2012
18

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Rebecca C Coll, Avril A B Robertson, Jae Jin Chae, Sarah C Higgins, Raúl Muñoz-Planillo, Marco C Inserra, Irina Vetter, Lara S Dungan, Brian G Monks, Andrea Stutz,[...]. Nat Med 2015
17

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Jianjin Shi, Yue Zhao, Kun Wang, Xuyan Shi, Yue Wang, Huanwei Huang, Yinghua Zhuang, Tao Cai, Fengchao Wang, Feng Shao. Nature 2015
16

Thioredoxin-interacting protein links oxidative stress to inflammasome activation.
Rongbin Zhou, Aubry Tardivel, Bernard Thorens, Inpyo Choi, Jürg Tschopp. Nat Immunol 2010
14

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
Nobuhiko Kayagaki, Irma B Stowe, Bettina L Lee, Karen O'Rourke, Keith Anderson, Søren Warming, Trinna Cuellar, Benjamin Haley, Merone Roose-Girma, Qui T Phung,[...]. Nature 2015
12

The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation.
Nathan Kelley, Devon Jeltema, Yanhui Duan, Yuan He. Int J Mol Sci 2019
639
12

MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition.
Rebecca C Coll, James R Hill, Christopher J Day, Alina Zamoshnikova, Dave Boucher, Nicholas L Massey, Jessica L Chitty, James A Fraser, Michael P Jennings, Avril A B Robertson,[...]. Nat Chem Biol 2019
265
12

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
Franz G Bauernfeind, Gabor Horvath, Andrea Stutz, Emad S Alnemri, Kelly MacDonald, David Speert, Teresa Fernandes-Alnemri, Jianghong Wu, Brian G Monks, Katherine A Fitzgerald,[...]. J Immunol 2009
12

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Peter Duewell, Hajime Kono, Katey J Rayner, Cherilyn M Sirois, Gregory Vladimer, Franz G Bauernfeind, George S Abela, Luigi Franchi, Gabriel Nuñez, Max Schnurr,[...]. Nature 2010
11

Pharmacological Inhibitors of the NLRP3 Inflammasome.
Ayesha Zahid, Bofeng Li, Arnaud John Kombe Kombe, Tengchuan Jin, Jinhui Tao. Front Immunol 2019
203
10

Non-canonical inflammasome activation targets caspase-11.
Nobuhiko Kayagaki, Søren Warming, Mohamed Lamkanfi, Lieselotte Vande Walle, Salina Louie, Jennifer Dong, Kim Newton, Yan Qu, Jinfeng Liu, Sherry Heldens,[...]. Nature 2011
10

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion.
Wan-ting He, Haoqiang Wan, Lichen Hu, Pengda Chen, Xin Wang, Zhe Huang, Zhang-Hua Yang, Chuan-Qi Zhong, Jiahuai Han. Cell Res 2015
866
9

New mitochondrial DNA synthesis enables NLRP3 inflammasome activation.
Zhenyu Zhong, Shuang Liang, Elsa Sanchez-Lopez, Feng He, Shabnam Shalapour, Xue-Jia Lin, Jerry Wong, Siyuan Ding, Ekihiro Seki, Bernd Schnabl,[...]. Nature 2018
364
9

NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux.
Yuan He, Melody Y Zeng, Dahai Yang, Benny Motro, Gabriel Núñez. Nature 2016
510
9

K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter.
Raúl Muñoz-Planillo, Peter Kuffa, Giovanny Martínez-Colón, Brenna L Smith, Thekkelnaycke M Rajendiran, Gabriel Núñez. Immunity 2013
9

Critical role for calcium mobilization in activation of the NLRP3 inflammasome.
Tomohiko Murakami, Johan Ockinger, Jiujiu Yu, Vanessa Byles, Aisleen McColl, Aldebaran M Hofer, Tiffany Horng. Proc Natl Acad Sci U S A 2012
474
9

Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation.
Shankar S Iyer, Qiong He, John R Janczy, Eric I Elliott, Zhenyu Zhong, Alicia K Olivier, Jeffrey J Sadler, Vickie Knepper-Adrian, Renzhi Han, Liang Qiao,[...]. Immunity 2013
483
9

The NLRP3 inflammasome: molecular activation and regulation to therapeutics.
Karen V Swanson, Meng Deng, Jenny P-Y Ting. Nat Rev Immunol 2019
9


NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component.
Hexin Shi, Ying Wang, Xiaohong Li, Xiaoming Zhan, Miao Tang, Maggy Fina, Lijing Su, David Pratt, Chun Hui Bu, Sara Hildebrand,[...]. Nat Immunol 2016
338
8

Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome.
Takuma Misawa, Michihiro Takahama, Tatsuya Kozaki, Hanna Lee, Jian Zou, Tatsuya Saitoh, Shizuo Akira. Nat Immunol 2013
499
8

Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors.
Yang Yang, Huanan Wang, Mohammed Kouadir, Houhui Song, Fushan Shi. Cell Death Dis 2019
430
8


Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity.
Hongbin He, Hua Jiang, Yun Chen, Jin Ye, Aoli Wang, Chao Wang, Qingsong Liu, Gaolin Liang, Xianming Deng, Wei Jiang,[...]. Nat Commun 2018
219
8

Targeting the NLRP3 inflammasome in inflammatory diseases.
Matthew S J Mangan, Edward J Olhava, William R Roush, H Martin Seidel, Gary D Glick, Eicke Latz. Nat Rev Drug Discov 2018
486
8

Inflammasomes: mechanism of action, role in disease, and therapeutics.
Haitao Guo, Justin B Callaway, Jenny P-Y Ting. Nat Med 2015
8

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death.
Jianjin Shi, Wenqing Gao, Feng Shao. Trends Biochem Sci 2017
858
7

Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling.
Haitao Wen, Denis Gris, Yu Lei, Sushmita Jha, Lu Zhang, Max Tze-Han Huang, Willie June Brickey, Jenny P-Y Ting. Nat Immunol 2011
7

Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction.
Chong-Shan Shi, Kevin Shenderov, Ning-Na Huang, Juraj Kabat, Mones Abu-Asab, Katherine A Fitzgerald, Alan Sher, John H Kehrl. Nat Immunol 2012
861
7

A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome Activation.
Jonathan L Schmid-Burgk, Dhruv Chauhan, Tobias Schmidt, Thomas S Ebert, Julia Reinhardt, Elmar Endl, Veit Hornung. J Biol Chem 2016
236
7

Redox regulation of NLRP3 inflammasomes: ROS as trigger or effector?
Justine M Abais, Min Xia, Yang Zhang, Krishna M Boini, Pin-Lan Li. Antioxid Redox Signal 2015
417
7

NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria.
Zhenyu Zhong, Atsushi Umemura, Elsa Sanchez-Lopez, Shuang Liang, Shabnam Shalapour, Jerry Wong, Feng He, Daniela Boassa, Guy Perkins, Syed Raza Ali,[...]. Cell 2016
565
7

Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders.
Hua Jiang, Hongbin He, Yun Chen, Wei Huang, Jinbo Cheng, Jin Ye, Aoli Wang, Jinhui Tao, Chao Wang, Qingsong Liu,[...]. J Exp Med 2017
265
7

Tranilast directly targets NLRP3 to treat inflammasome-driven diseases.
Yi Huang, Hua Jiang, Yun Chen, Xiaqiong Wang, Yanqing Yang, Jinhui Tao, Xianming Deng, Gaolin Liang, Huafeng Zhang, Wei Jiang,[...]. EMBO Mol Med 2018
170
7

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica.
Catherine Dostert, Virginie Pétrilli, Robin Van Bruggen, Chad Steele, Brooke T Mossman, Jürg Tschopp. Science 2008
7

Inflammasomes: mechanism of assembly, regulation and signalling.
Petr Broz, Vishva M Dixit. Nat Rev Immunol 2016
7

The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation.
Naeha Subramanian, Kannan Natarajan, Menna R Clatworthy, Ze Wang, Ronald N Germain. Cell 2013
388
7

PINK1-parkin pathway of mitophagy protects against contrast-induced acute kidney injury via decreasing mitochondrial ROS and NLRP3 inflammasome activation.
Qisheng Lin, Shu Li, Na Jiang, Xinghua Shao, Minfang Zhang, Haijiao Jin, Zhen Zhang, Jianxiao Shen, Yijun Zhou, Wenyan Zhou,[...]. Redox Biol 2019
131
7

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice.
Auvro R Mridha, Alexander Wree, Avril A B Robertson, Matthew M Yeh, Casey D Johnson, Derrick M Van Rooyen, Fahrettin Haczeyni, Narci C-H Teoh, Christopher Savard, George N Ioannou,[...]. J Hepatol 2017
407
7

Mechanism and Regulation of NLRP3 Inflammasome Activation.
Yuan He, Hideki Hara, Gabriel Núñez. Trends Biochem Sci 2016
7

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production.
Tatsuya Saitoh, Naonobu Fujita, Myoung Ho Jang, Satoshi Uematsu, Bo-Gie Yang, Takashi Satoh, Hiroko Omori, Takeshi Noda, Naoki Yamamoto, Masaaki Komatsu,[...]. Nature 2008
6

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease.
Paul M Ridker, Brendan M Everett, Tom Thuren, Jean G MacFadyen, William H Chang, Christie Ballantyne, Francisco Fonseca, Jose Nicolau, Wolfgang Koenig, Stefan D Anker,[...]. N Engl J Med 2017
6

Interplay Between NLRP3 Inflammasome and Autophagy.
Monika Biasizzo, Nataša Kopitar-Jerala. Front Immunol 2020
52
11

The role of mitochondria in NLRP3 inflammasome activation.
Qiuyun Liu, Danyan Zhang, Diyu Hu, Xiangmei Zhou, Yang Zhou. Mol Immunol 2018
143
6

Gout-associated uric acid crystals activate the NALP3 inflammasome.
Fabio Martinon, Virginie Pétrilli, Annick Mayor, Aubry Tardivel, Jürg Tschopp. Nature 2006
6

Inflammasomes in health and disease.
Till Strowig, Jorge Henao-Mejia, Eran Elinav, Richard Flavell. Nature 2012
6

Mitochondrial DNA stress primes the antiviral innate immune response.
A Phillip West, William Khoury-Hanold, Matthew Staron, Michal C Tal, Cristiana M Pineda, Sabine M Lang, Megan Bestwick, Brett A Duguay, Nuno Raimundo, Donna A MacDuff,[...]. Nature 2015
761
6

Mitochondrial DNA in inflammation and immunity.
Joel S Riley, Stephen Wg Tait. EMBO Rep 2020
151
6


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.