A citation-based method for searching scientific literature

Francisco J Tejedor, Barbara Hämmerle. FEBS J 2011
Times Cited: 146







List of co-cited articles
1029 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


The role of DYRK1A in neurodegenerative diseases.
Jerzy Wegiel, Cheng-Xin Gong, Yu-Wen Hwang. FEBS J 2011
166
35

Activation, regulation, and inhibition of DYRK1A.
Walter Becker, Wolfgang Sippl. FEBS J 2011
140
34

Dyrk1A haploinsufficiency affects viability and causes developmental delay and abnormal brain morphology in mice.
Vassiliki Fotaki, Mara Dierssen, Soledad Alcántara, Salvador Martínez, Eulàlia Martí, Caty Casas, Joana Visa, Eduardo Soriano, Xavier Estivill, Maria L Arbonés. Mol Cell Biol 2002
238
32

Truncation of the Down syndrome candidate gene DYRK1A in two unrelated patients with microcephaly.
Rikke S Møller, Sabine Kübart, Maria Hoeltzenbein, Babett Heye, Ida Vogel, Christian P Hansen, Corinna Menzel, Reinhard Ullmann, Niels Tommerup, Hans-Hilger Ropers,[...]. Am J Hum Genet 2008
117
27

Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A.
Yasushi Ogawa, Yosuke Nonaka, Toshiyasu Goto, Eriko Ohnishi, Toshiyuki Hiramatsu, Isao Kii, Miyo Yoshida, Teikichi Ikura, Hiroshi Onogi, Hiroshi Shibuya,[...]. Nat Commun 2010
178
27

Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans.
Rafael De la Torre, Susana De Sola, Meritxell Pons, Arnaud Duchon, María Martínez de Lagran, Magí Farré, Montserrat Fitó, Bessy Benejam, Klaus Langohr, Joan Rodriguez,[...]. Mol Nutr Food Res 2014
177
27

Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome.
X Altafaj, M Dierssen, C Baamonde, E Martí, J Visa, J Guimerà, M Oset, J R González, J Flórez, C Fillat,[...]. Hum Mol Genet 2001
291
26



Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling.
Barbara Hämmerle, Edgar Ulin, Jordi Guimera, Walter Becker, François Guillemot, Francisco J Tejedor. Development 2011
84
27

minibrain: a new protein kinase family involved in postembryonic neurogenesis in Drosophila.
F Tejedor, X R Zhu, E Kaltenbach, A Ackermann, A Baumann, I Canal, M Heisenberg, K F Fischbach, O Pongs. Neuron 1995
299
23



The Down syndrome-related protein kinase DYRK1A phosphorylates p27(Kip1) and Cyclin D1 and induces cell cycle exit and neuronal differentiation.
Ulf Soppa, Julian Schumacher, Victoria Florencio Ortiz, Tobias Pasqualon, Francisco J Tejedor, Walter Becker. Cell Cycle 2014
101
22

Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation.
Nora Göckler, Guillermo Jofre, Chrisovalantis Papadopoulos, Ulf Soppa, Francisco J Tejedor, Walter Becker. FEBS J 2009
166
21

NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21.
Joseph R Arron, Monte M Winslow, Alberto Polleri, Ching-Pin Chang, Hai Wu, Xin Gao, Joel R Neilson, Lei Chen, Jeremy J Heit, Seung K Kim,[...]. Nature 2006
498
21

The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease.
Ryo Kimura, Kouzin Kamino, Mitsuko Yamamoto, Aidaralieva Nuripa, Tomoyuki Kida, Hiroaki Kazui, Ryota Hashimoto, Toshihisa Tanaka, Takashi Kudo, Hidehisa Yamagata,[...]. Hum Mol Genet 2007
181
20

Function and regulation of Dyrk1A: towards understanding Down syndrome.
Joongkyu Park, Woo-Joo Song, Kwang Chul Chung. Cell Mol Life Sci 2009
136
20

DYRK1A: a master regulatory protein controlling brain growth.
Fayçal Guedj, Patricia Lopes Pereira, Sonia Najas, Maria-Jose Barallobre, Caroline Chabert, Benoit Souchet, Catherine Sebrie, Catherine Verney, Yann Herault, Mariona Arbones,[...]. Neurobiol Dis 2012
94
21

Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease.
Soo-Ryoon Ryoo, Hyun-Jeong Cho, Hye-Won Lee, Hey Kyeong Jeong, Chinzorig Radnaabazar, Yeun-Soo Kim, Min-Jeong Kim, Mi-Young Son, Hyemyung Seo, Sul-Hee Chung,[...]. J Neurochem 2008
137
19

DYRK1A BAC transgenic mice show altered synaptic plasticity with learning and memory defects.
Kyoung-Jin Ahn, Hey Kyeong Jeong, Han-Saem Choi, Soo-Ryoon Ryoo, Yeon Ju Kim, Jun-Seo Goo, Se-Young Choi, Jung-Soo Han, Ilho Ha, Woo-Joo Song. Neurobiol Dis 2006
155
18

The selectivity of protein kinase inhibitors: a further update.
Jenny Bain, Lorna Plater, Matt Elliott, Natalia Shpiro, C James Hastie, Hilary McLauchlan, Iva Klevernic, J Simon C Arthur, Dario R Alessi, Philip Cohen. Biochem J 2007
18

Alterations in the phenotype of neocortical pyramidal cells in the Dyrk1A+/- mouse.
R Benavides-Piccione, M Dierssen, I Ballesteros-Yáñez, M Martínez de Lagrán, M L Arbonés, V Fotaki, J DeFelipe, G N Elston. Neurobiol Dis 2005
77
23

The specificities of protein kinase inhibitors: an update.
Jenny Bain, Hilary McLauchlan, Matthew Elliott, Philip Cohen. Biochem J 2003
18


The DYRK1A gene is a cause of syndromic intellectual disability with severe microcephaly and epilepsy.
Jean-Benoît Courcet, Laurence Faivre, Perrine Malzac, Alice Masurel-Paulet, Estelle Lopez, Patrick Callier, Laetitia Lambert, Martine Lemesle, Julien Thevenon, Nadège Gigot,[...]. J Med Genet 2012
68
26

Down syndrome: the brain in trisomic mode.
Mara Dierssen. Nat Rev Neurosci 2012
161
18

Intragenic deletion in DYRK1A leads to mental retardation and primary microcephaly.
B W M van Bon, A Hoischen, J Hehir-Kwa, A P M de Brouwer, C Ruivenkamp, A C J Gijsbers, C L Marcelis, N de Leeuw, J A Veltman, H G Brunner,[...]. Clin Genet 2011
74
24

Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome.
Fei Liu, Zhihou Liang, Jerzy Wegiel, Yu-Wen Hwang, Khalid Iqbal, Inge Grundke-Iqbal, Narayan Ramakrishna, Cheng-Xin Gong. FASEB J 2008
160
17

Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells.
Joongkyu Park, Yohan Oh, Lang Yoo, Min-Su Jung, Woo-Joo Song, Sang-Hun Lee, Hyemyung Seo, Kwang Chul Chung. J Biol Chem 2010
83
20

A human homologue of Drosophila minibrain (MNB) is expressed in the neuronal regions affected in Down syndrome and maps to the critical region.
J Guimerá, C Casas, C Pucharcòs, A Solans, A Domènech, A M Planas, J Ashley, M Lovett, X Estivill, M A Pritchard. Hum Mol Genet 1996
172
17

DYRK1A: a potential drug target for multiple Down syndrome neuropathologies.
Walter Becker, Ulf Soppa, Francisco J Tejedor. CNS Neurol Disord Drug Targets 2014
66
25

DYRK1A in neurodegeneration and cancer: Molecular basis and clinical implications.
Ramzi Abbassi, Terrance G Johns, Michael Kassiou, Lenka Munoz. Pharmacol Ther 2015
96
17


Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B.
Tania Tahtouh, Jonathan M Elkins, Panagis Filippakopoulos, Meera Soundararajan, Guillaume Burgy, Emilie Durieu, Claude Cochet, Ralf S Schmid, Donald C Lo, Florent Delhommel,[...]. J Med Chem 2012
138
16

Trisomy-driven overexpression of DYRK1A kinase in the brain of subjects with Down syndrome.
Wieslaw K Dowjat, Tatyana Adayev, Izabela Kuchna, Krzysztof Nowicki, Sonia Palminiello, Yu Wen Hwang, Jerzy Wegiel. Neurosci Lett 2007
127
16

Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs.
Pamela A Lochhead, Gary Sibbet, Nick Morrice, Vaughn Cleghon. Cell 2005
214
16

A novel DYRK1A (dual specificity tyrosine phosphorylation-regulated kinase 1A) inhibitor for the treatment of Alzheimer's disease: effect on Tau and amyloid pathologies in vitro.
Séverine Coutadeur, Hélène Benyamine, Laurence Delalonde, Catherine de Oliveira, Bertrand Leblond, Alicia Foucourt, Thierry Besson, Anne-Sophie Casagrande, Thierry Taverne, Angélique Girard,[...]. J Neurochem 2015
77
20

Disruptive de novo mutations of DYRK1A lead to a syndromic form of autism and ID.
B W M van Bon, B P Coe, R Bernier, C Green, J Gerdts, K Witherspoon, T Kleefstra, M H Willemsen, R Kumar, P Bosco,[...]. Mol Psychiatry 2016
96
16

Green tea polyphenols rescue of brain defects induced by overexpression of DYRK1A.
Fayçal Guedj, Catherine Sébrié, Isabelle Rivals, Aurelie Ledru, Evelyne Paly, Jean C Bizot, Desmond Smith, Edward Rubin, Brigitte Gillet, Mariona Arbones,[...]. PLoS One 2009
142
15


Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A.
S Himpel, P Panzer, K Eirmbter, H Czajkowska, M Sayed, L C Packman, T Blundell, H Kentrup, J Grötzinger, H G Joost,[...]. Biochem J 2001
123
15

Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition.
Meera Soundararajan, Annette K Roos, Pavel Savitsky, Panagis Filippakopoulos, Arminja N Kettenbach, Jesper V Olsen, Scott A Gerber, Jeyanthy Eswaran, Stefan Knapp, Jonathan M Elkins. Structure 2013
97
15

Excitation/inhibition balance and learning are modified by Dyrk1a gene dosage.
Benoit Souchet, Fayçal Guedj, Ignasi Sahún, Arnaud Duchon, Fabrice Daubigney, Anne Badel, Yuchio Yanagawa, Maria Jose Barallobre, Mara Dierssen, Eugene Yu,[...]. Neurobiol Dis 2014
72
20

Safety and efficacy of cognitive training plus epigallocatechin-3-gallate in young adults with Down's syndrome (TESDAD): a double-blind, randomised, placebo-controlled, phase 2 trial.
Rafael de la Torre, Susana de Sola, Gimena Hernandez, Magí Farré, Jesus Pujol, Joan Rodriguez, Josep María Espadaler, Klaus Langohr, Aida Cuenca-Royo, Alessandro Principe,[...]. Lancet Neurol 2016
153
15

Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing.
Mansour Debdab, François Carreaux, Steven Renault, Meera Soundararajan, Oleg Fedorov, Panagis Filippakopoulos, Olivier Lozach, Lucie Babault, Tania Tahtouh, Blandine Baratte,[...]. J Med Chem 2011
97
14

Increased dosage of Dyrk1A alters alternative splicing factor (ASF)-regulated alternative splicing of tau in Down syndrome.
Jianhua Shi, Tianyi Zhang, Chunlei Zhou, Muhammad Omar Chohan, Xiaosong Gu, Jerzy Wegiel, Jianhua Zhou, Yu-Wen Hwang, Khalid Iqbal, Inge Grundke-Iqbal,[...]. J Biol Chem 2008
112
14

Dyrk1A influences neuronal morphogenesis through regulation of cytoskeletal dynamics in mammalian cortical neurons.
M Martinez de Lagran, R Benavides-Piccione, I Ballesteros-Yañez, M Calvo, M Morales, C Fillat, J Defelipe, G J A Ramakers, M Dierssen. Cereb Cortex 2012
53
26

β-carboline compounds, including harmine, inhibit DYRK1A and tau phosphorylation at multiple Alzheimer's disease-related sites.
Danielle Frost, Bessie Meechoovet, Tong Wang, Stephen Gately, Marco Giorgetti, Irina Shcherbakova, Travis Dunckley. PLoS One 2011
105
14

DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly.
Larisa Litovchick, Laurence A Florens, Selene K Swanson, Michael P Washburn, James A DeCaprio. Genes Dev 2011
176
14


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.