Roberto Zoncu, Alejo Efeyan, David M Sabatini. Nat Rev Mol Cell Biol 2011
Times Cited: 2824
Times Cited: 2824
Times Cited
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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.
Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan. Nat Cell Biol 2011
Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan. Nat Cell Biol 2011
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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.
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Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
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ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery.
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Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2.
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mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery.
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Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.
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mTOR signalling and cellular metabolism are mutual determinants in cancer.
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Mechanism and medical implications of mammalian autophagy.
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Overcoming mTOR resistance mutations with a new-generation mTOR inhibitor.
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Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton.
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GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.