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Times Cited: 908
Times Cited: 908
Times Cited
Times Co-cited
Similarity
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy.
Michael Lazarou, Danielle A Sliter, Lesley A Kane, Shireen A Sarraf, Chunxin Wang, Jonathon L Burman, Dionisia P Sideris, Adam I Fogel, Richard J Youle. Nature 2015
Michael Lazarou, Danielle A Sliter, Lesley A Kane, Shireen A Sarraf, Chunxin Wang, Jonathon L Burman, Dionisia P Sideris, Adam I Fogel, Richard J Youle. Nature 2015
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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy.
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy.
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PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.
Derek P Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A Gautier, Jie Shen, Mark R Cookson, Richard J Youle. PLoS Biol 2010
Derek P Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A Gautier, Jie Shen, Mark R Cookson, Richard J Youle. PLoS Biol 2010
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Ubiquitin is phosphorylated by PINK1 to activate parkin.
Fumika Koyano, Kei Okatsu, Hidetaka Kosako, Yasushi Tamura, Etsu Go, Mayumi Kimura, Yoko Kimura, Hikaru Tsuchiya, Hidehito Yoshihara, Takatsugu Hirokawa,[...]. Nature 2014
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Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL.
Seok Min Jin, Michael Lazarou, Chunxin Wang, Lesley A Kane, Derek P Narendra, Richard J Youle. J Cell Biol 2010
Seok Min Jin, Michael Lazarou, Chunxin Wang, Lesley A Kane, Derek P Narendra, Richard J Youle. J Cell Biol 2010
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Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance.
Sarah Pickles, Pierre Vigié, Richard J Youle. Curr Biol 2018
Sarah Pickles, Pierre Vigié, Richard J Youle. Curr Biol 2018
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Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells.
Lei Liu, Du Feng, Guo Chen, Ming Chen, Qiaoxia Zheng, Pingping Song, Qi Ma, Chongzhuo Zhu, Rui Wang, Wanjun Qi,[...]. Nat Cell Biol 2012
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PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity.
Lesley A Kane, Michael Lazarou, Adam I Fogel, Yan Li, Koji Yamano, Shireen A Sarraf, Soojay Banerjee, Richard J Youle. J Cell Biol 2014
Lesley A Kane, Michael Lazarou, Adam I Fogel, Yan Li, Koji Yamano, Shireen A Sarraf, Soojay Banerjee, Richard J Youle. J Cell Biol 2014
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The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy.
Jin-Mi Heo, Alban Ordureau, Joao A Paulo, Jesse Rinehart, J Wade Harper. Mol Cell 2015
Jin-Mi Heo, Alban Ordureau, Joao A Paulo, Jesse Rinehart, J Wade Harper. Mol Cell 2015
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Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy.
Nickie C Chan, Anna M Salazar, Anh H Pham, Michael J Sweredoski, Natalie J Kolawa, Robert L J Graham, Sonja Hess, David C Chan. Hum Mol Genet 2011
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Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy.
Gian-Luca McLelland, Thomas Goiran, Wei Yi, Geneviève Dorval, Carol X Chen, Nadine D Lauinger, Andrea I Krahn, Sepideh Valimehr, Aleksandar Rakovic, Isabelle Rouiller,[...]. Elife 2018
Gian-Luca McLelland, Thomas Goiran, Wei Yi, Geneviève Dorval, Carol X Chen, Nadine D Lauinger, Andrea I Krahn, Sepideh Valimehr, Aleksandar Rakovic, Isabelle Rouiller,[...]. Elife 2018
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PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy.
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Noriyuki Matsuda, Shigeto Sato, Kahori Shiba, Kei Okatsu, Keiko Saisho, Clement A Gautier, Yu-Shin Sou, Shinji Saiki, Sumihiro Kawajiri, Fumiaki Sato,[...]. J Cell Biol 2010
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PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility.
Xinnan Wang, Dominic Winter, Ghazaleh Ashrafi, Julia Schlehe, Yao Liang Wong, Dennis Selkoe, Sarah Rice, Judith Steen, Matthew J LaVoie, Thomas L Schwarz. Cell 2011
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PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65.
Chandana Kondapalli, Agne Kazlauskaite, Ning Zhang, Helen I Woodroof, David G Campbell, Robert Gourlay, Lynn Burchell, Helen Walden, Thomas J Macartney, Maria Deak,[...]. Open Biol 2012
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The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease.
Alicia M Pickrell, Richard J Youle. Neuron 2015
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PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1.
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Mitofusin 2 tethers endoplasmic reticulum to mitochondria.
Olga Martins de Brito, Luca Scorrano. Nature 2008
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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism.
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Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
Shireen A Sarraf, Malavika Raman, Virginia Guarani-Pereira, Mathew E Sowa, Edward L Huttlin, Steven P Gygi, J Wade Harper. Nature 2013
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The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy.
Baris Bingol, Joy S Tea, Lilian Phu, Mike Reichelt, Corey E Bakalarski, Qinghua Song, Oded Foreman, Donald S Kirkpatrick, Morgan Sheng. Nature 2014
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Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis.
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Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development.
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PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria.
Yun Chen, Gerald W Dorn. Science 2013
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Hereditary early-onset Parkinson's disease caused by mutations in PINK1.
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Enza Maria Valente, Patrick M Abou-Sleiman, Viviana Caputo, Miratul M K Muqit, Kirsten Harvey, Suzana Gispert, Zeeshan Ali, Domenico Del Turco, Anna Rita Bentivoglio, Daniel G Healy,[...]. Science 2004
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Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand.
Thomas G McWilliams, Alan R Prescott, Lambert Montava-Garriga, Graeme Ball, François Singh, Erica Barini, Miratul M K Muqit, Simon P Brooks, Ian G Ganley. Cell Metab 2018
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Parkin-independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain.
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Essential role for Nix in autophagic maturation of erythroid cells.
Hector Sandoval, Perumal Thiagarajan, Swapan K Dasgupta, Armin Schumacher, Josef T Prchal, Min Chen, Jin Wang. Nature 2008
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PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.
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Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria.
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Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane.
Saori R Yoshii, Chieko Kishi, Naotada Ishihara, Noboru Mizushima. J Biol Chem 2011
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Nix is a selective autophagy receptor for mitochondrial clearance.
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Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy.
Ming Chen, Ziheng Chen, Yueying Wang, Zheng Tan, Chongzhuo Zhu, Yanjun Li, Zhe Han, Linbo Chen, Ruize Gao, Lei Liu,[...]. Autophagy 2016
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Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation.
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ER tubules mark sites of mitochondrial division.
Jonathan R Friedman, Laura L Lackner, Matthew West, Jared R DiBenedetto, Jodi Nunnari, Gia K Voeltz. Science 2011
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Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment.
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Mechanisms of mitophagy in cellular homeostasis, physiology and pathology.
Konstantinos Palikaras, Eirini Lionaki, Nektarios Tavernarakis. Nat Cell Biol 2018
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Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation.
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Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission.
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Measuring In Vivo Mitophagy.
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FKBP8 recruits LC3A to mediate Parkin-independent mitophagy.
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Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy.
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Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin.
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ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy.
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Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
Evandro F Fang, Yujun Hou, Konstantinos Palikaras, Bryan A Adriaanse, Jesse S Kerr, Beimeng Yang, Sofie Lautrup, Md Mahdi Hasan-Olive, Domenica Caponio, Xiuli Dan,[...]. Nat Neurosci 2019
Evandro F Fang, Yujun Hou, Konstantinos Palikaras, Bryan A Adriaanse, Jesse S Kerr, Beimeng Yang, Sofie Lautrup, Md Mahdi Hasan-Olive, Domenica Caponio, Xiuli Dan,[...]. Nat Neurosci 2019
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Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin.
Michael Lazarou, Seok Min Jin, Lesley A Kane, Richard J Youle. Dev Cell 2012
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Mitochondrial fission facilitates the selective mitophagy of protein aggregates.
Jonathon L Burman, Sarah Pickles, Chunxin Wang, Shiori Sekine, Jose Norberto S Vargas, Zhe Zhang, Alice M Youle, Catherine L Nezich, Xufeng Wu, John A Hammer,[...]. J Cell Biol 2017
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Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65.
Agne Kazlauskaite, Chandana Kondapalli, Robert Gourlay, David G Campbell, Maria Stella Ritorto, Kay Hofmann, Dario R Alessi, Axel Knebel, Matthias Trost, Miratul M K Muqit. Biochem J 2014
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.