Alexander W Koch, Thomas Mathivet, Bruno Larrivée, Raymond K Tong, Joe Kowalski, Laurence Pibouin-Fragner, Karine Bouvrée, Scott Stawicki, Katrina Nicholes, Nisha Rathore, Suzie J Scales, Elizabeth Luis, Raquel del Toro, Catarina Freitas, Christiane Bréant, Annie Michaud, Pierre Corvol, Jean-Léon Thomas, Yan Wu, Franklin Peale, Ryan J Watts, Marc Tessier-Lavigne, Anil Bagri, Anne Eichmann. Dev Cell 2011
Times Cited: 134
Times Cited: 134
Times Cited
Times Co-cited
Similarity
Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability.
Christopher A Jones, Nyall R London, Haoyu Chen, Kye Won Park, Dominique Sauvaget, Rebecca A Stockton, Joshua D Wythe, Wonhee Suh, Frederic Larrieu-Lahargue, Yoh-Suke Mukouyama,[...]. Nat Med 2008
Christopher A Jones, Nyall R London, Haoyu Chen, Kye Won Park, Dominique Sauvaget, Rebecca A Stockton, Joshua D Wythe, Wonhee Suh, Frederic Larrieu-Lahargue, Yoh-Suke Mukouyama,[...]. Nat Med 2008
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Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity.
Christopher A Jones, Naoyuki Nishiya, Nyall R London, Weiquan Zhu, Lise K Sorensen, Aubrey C Chan, Chinten J Lim, Haoyu Chen, Qisheng Zhang, Peter G Schultz,[...]. Nat Cell Biol 2009
Christopher A Jones, Naoyuki Nishiya, Nyall R London, Weiquan Zhu, Lise K Sorensen, Aubrey C Chan, Chinten J Lim, Haoyu Chen, Qisheng Zhang, Peter G Schultz,[...]. Nat Cell Biol 2009
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Robo4 is a vascular-specific receptor that inhibits endothelial migration.
Kye Won Park, Clayton M Morrison, Lise K Sorensen, Christopher A Jones, Yi Rao, Chi-Bin Chien, Jane Y Wu, Lisa D Urness, Dean Y Li. Dev Biol 2003
Kye Won Park, Clayton M Morrison, Lise K Sorensen, Christopher A Jones, Yi Rao, Chi-Bin Chien, Jane Y Wu, Lisa D Urness, Dean Y Li. Dev Biol 2003
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Magic roundabout is a new member of the roundabout receptor family that is endothelial specific and expressed at sites of active angiogenesis.
Lukasz Huminiecki, Michael Gorn, Steven Suchting, Richard Poulsom, Roy Bicknell. Genomics 2002
Lukasz Huminiecki, Michael Gorn, Steven Suchting, Richard Poulsom, Roy Bicknell. Genomics 2002
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Active involvement of Robo1 and Robo4 in filopodia formation and endothelial cell motility mediated via WASP and other actin nucleation-promoting factors.
Helen Sheldon, Maud Andre, John A Legg, Paul Heal, John M Herbert, Richard Sainson, Anshula S Sharma, Jan K Kitajewski, Victoria L Heath, Roy Bicknell. FASEB J 2009
Helen Sheldon, Maud Andre, John A Legg, Paul Heal, John M Herbert, Richard Sainson, Anshula S Sharma, Jan K Kitajewski, Victoria L Heath, Roy Bicknell. FASEB J 2009
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The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system.
Xiaowei Lu, Ferdinand Le Noble, Li Yuan, Quingjan Jiang, Benjamin De Lafarge, Daisuke Sugiyama, Christiane Bréant, Filip Claes, Frederik De Smet, Jean-Léon Thomas,[...]. Nature 2004
Xiaowei Lu, Ferdinand Le Noble, Li Yuan, Quingjan Jiang, Benjamin De Lafarge, Daisuke Sugiyama, Christiane Bréant, Filip Claes, Frederik De Smet, Jean-Léon Thomas,[...]. Nature 2004
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Vascular Robo4 restricts proangiogenic VEGF signaling in breast.
Rebecca Marlow, Mikhail Binnewies, Lise K Sorensen, Stefanie D Monica, Phyllis Strickland, E Camilla Forsberg, Dean Y Li, Lindsay Hinck. Proc Natl Acad Sci U S A 2010
Rebecca Marlow, Mikhail Binnewies, Lise K Sorensen, Stefanie D Monica, Phyllis Strickland, E Camilla Forsberg, Dean Y Li, Lindsay Hinck. Proc Natl Acad Sci U S A 2010
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Soluble Robo4 receptor inhibits in vivo angiogenesis and endothelial cell migration.
Steven Suchting, Paul Heal, Kiki Tahtis, Lorna M Stewart, Roy Bicknell. FASEB J 2005
Steven Suchting, Paul Heal, Kiki Tahtis, Lorna M Stewart, Roy Bicknell. FASEB J 2005
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Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity.
Biao Wang, Yang Xiao, Bei Bei Ding, Na Zhang, Xiao bin Yuan, Lü Gui, Kai Xian Qian, Shumin Duan, Zhengjun Chen, Yi Rao,[...]. Cancer Cell 2003
Biao Wang, Yang Xiao, Bei Bei Ding, Na Zhang, Xiao bin Yuan, Lü Gui, Kai Xian Qian, Shumin Duan, Zhengjun Chen, Yi Rao,[...]. Cancer Cell 2003
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Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance.
K Brose, K S Bland, K H Wang, D Arnott, W Henzel, C S Goodman, M Tessier-Lavigne, T Kidd. Cell 1999
K Brose, K S Bland, K H Wang, D Arnott, W Henzel, C S Goodman, M Tessier-Lavigne, T Kidd. Cell 1999
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Structural insights into the Slit-Robo complex.
Cecile Morlot, Nicole M Thielens, Raimond B G Ravelli, Wieger Hemrika, Roland A Romijn, Piet Gros, Stephen Cusack, Andrew A McCarthy. Proc Natl Acad Sci U S A 2007
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Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization.
Nicolas Rama, Alexandre Dubrac, Thomas Mathivet, Róisín-Ana Ní Chárthaigh, Gael Genet, Brunella Cristofaro, Laurence Pibouin-Fragner, Le Ma, Anne Eichmann, Alain Chédotal. Nat Med 2015
Nicolas Rama, Alexandre Dubrac, Thomas Mathivet, Róisín-Ana Ní Chárthaigh, Gael Genet, Brunella Cristofaro, Laurence Pibouin-Fragner, Le Ma, Anne Eichmann, Alain Chédotal. Nat Med 2015
19
The Robo4 cytoplasmic domain is dispensable for vascular permeability and neovascularization.
Feng Zhang, Claudia Prahst, Thomas Mathivet, Laurence Pibouin-Fragner, Jiasheng Zhang, Gael Genet, Raymond Tong, Alexandre Dubrac, Anne Eichmann. Nat Commun 2016
Feng Zhang, Claudia Prahst, Thomas Mathivet, Laurence Pibouin-Fragner, Jiasheng Zhang, Gael Genet, Raymond Tong, Alexandre Dubrac, Anne Eichmann. Nat Commun 2016
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A three-kilobase fragment of the human Robo4 promoter directs cell type-specific expression in endothelium.
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Repulsive axon guidance molecule Slit3 is a novel angiogenic factor.
Bing Zhang, Ursula M Dietrich, Jian-Guo Geng, Roy Bicknell, Jeffrey D Esko, Lianchun Wang. Blood 2009
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Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors.
T Kidd, K Brose, K J Mitchell, R D Fetter, M Tessier-Lavigne, C S Goodman, G Tear. Cell 1998
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Signaling switch of the axon guidance receptor Robo3 during vertebrate evolution.
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Pavol Zelina, Heike Blockus, Yvrick Zagar, Amélie Péres, François Friocourt, Zhuhao Wu, Nicolas Rama, Coralie Fouquet, Erhard Hohenester, Marc Tessier-Lavigne,[...]. Neuron 2014
17
Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and influenza.
Nyall R London, Weiquan Zhu, Fernando A Bozza, Matthew C P Smith, Daniel M Greif, Lise K Sorensen, Luming Chen, Yuuki Kaminoh, Aubrey C Chan, Samuel F Passi,[...]. Sci Transl Med 2010
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Magic roundabout, a tumor endothelial marker: expression and signaling.
Pankaj Seth, Yanfeng Lin, Jun-ichi Hanai, Venkatesha Shivalingappa, Mabel P Duyao, Vikas P Sukhatme. Biochem Biophys Res Commun 2005
Pankaj Seth, Yanfeng Lin, Jun-ichi Hanai, Venkatesha Shivalingappa, Mabel P Duyao, Vikas P Sukhatme. Biochem Biophys Res Commun 2005
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roundabout4 is essential for angiogenesis in vivo.
Victoria M Bedell, Sang-Yeob Yeo, Kye Won Park, Jeffrey Chung, Pankaj Seth, Venkatesha Shivalingappa, Jinhua Zhao, Tomoko Obara, Vikas P Sukhatme, Iain A Drummond,[...]. Proc Natl Acad Sci U S A 2005
Victoria M Bedell, Sang-Yeob Yeo, Kye Won Park, Jeffrey Chung, Pankaj Seth, Venkatesha Shivalingappa, Jinhua Zhao, Tomoko Obara, Vikas P Sukhatme, Iain A Drummond,[...]. Proc Natl Acad Sci U S A 2005
15
Activation of the UNC5B receptor by Netrin-1 inhibits sprouting angiogenesis.
Bruno Larrivée, Catarina Freitas, Marc Trombe, Xiang Lv, Benjamin Delafarge, Li Yuan, Karine Bouvrée, Christiane Bréant, Raquel Del Toro, Nicolas Bréchot,[...]. Genes Dev 2007
Bruno Larrivée, Catarina Freitas, Marc Trombe, Xiang Lv, Benjamin Delafarge, Li Yuan, Karine Bouvrée, Christiane Bréant, Raquel Del Toro, Nicolas Bréchot,[...]. Genes Dev 2007
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VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia.
Holger Gerhardt, Matthew Golding, Marcus Fruttiger, Christiana Ruhrberg, Andrea Lundkvist, Alexandra Abramsson, Michael Jeltsch, Christopher Mitchell, Kari Alitalo, David Shima,[...]. J Cell Biol 2003
Holger Gerhardt, Matthew Golding, Marcus Fruttiger, Christiana Ruhrberg, Andrea Lundkvist, Alexandra Abramsson, Michael Jeltsch, Christopher Mitchell, Kari Alitalo, David Shima,[...]. J Cell Biol 2003
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Robo4 signaling in endothelial cells implies attraction guidance mechanisms.
Sukhbir Kaur, Maria Domenica Castellone, Victoria M Bedell, Martha Konar, J Silvio Gutkind, Ramani Ramchandran. J Biol Chem 2006
Sukhbir Kaur, Maria Domenica Castellone, Victoria M Bedell, Martha Konar, J Silvio Gutkind, Ramani Ramchandran. J Biol Chem 2006
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Slit is the midline repellent for the robo receptor in Drosophila.
T Kidd, K S Bland, C S Goodman. Cell 1999
T Kidd, K S Bland, C S Goodman. Cell 1999
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Molecular mechanisms and clinical applications of angiogenesis.
Peter Carmeliet, Rakesh K Jain. Nature 2011
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A GABP-binding element in the Robo4 promoter is necessary for endothelial expression in vivo.
Yoshiaki Okada, Enjing Jin, Vesna Nikolova-Krstevski, Kiichiro Yano, Ju Liu, David Beeler, Katherine Spokes, Mie Kitayama, Nobuaki Funahashi, Takefumi Doi,[...]. Blood 2008
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Structural and functional analysis of slit and heparin binding to immunoglobulin-like domains 1 and 2 of Drosophila Robo.
Noémi Fukuhara, Jason A Howitt, Sadaf-Ahmahni Hussain, Erhard Hohenester. J Biol Chem 2008
Noémi Fukuhara, Jason A Howitt, Sadaf-Ahmahni Hussain, Erhard Hohenester. J Biol Chem 2008
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Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting.
Lars Jakobsson, Claudio A Franco, Katie Bentley, Russell T Collins, Bas Ponsioen, Irene M Aspalter, Ian Rosewell, Marta Busse, Gavin Thurston, Alexander Medvinsky,[...]. Nat Cell Biol 2010
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Autoinhibition of UNC5b revealed by the cytoplasmic domain structure of the receptor.
Rui Wang, Zhiyi Wei, Hao Jin, Hao Wu, Cong Yu, Wenyu Wen, Ling-Nga Chan, Zilong Wen, Mingjie Zhang. Mol Cell 2009
Rui Wang, Zhiyi Wei, Hao Jin, Hao Wu, Cong Yu, Wenyu Wen, Ling-Nga Chan, Zilong Wen, Mingjie Zhang. Mol Cell 2009
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Common mechanisms of nerve and blood vessel wiring.
Peter Carmeliet, Marc Tessier-Lavigne. Nature 2005
Peter Carmeliet, Marc Tessier-Lavigne. Nature 2005
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Axon guidance molecules in vascular patterning.
Ralf H Adams, Anne Eichmann. Cold Spring Harb Perspect Biol 2010
Ralf H Adams, Anne Eichmann. Cold Spring Harb Perspect Biol 2010
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Robo4 cooperates with CXCR4 to specify hematopoietic stem cell localization to bone marrow niches.
Stephanie Smith-Berdan, Andrew Nguyen, Deena Hassanein, Matthew Zimmer, Fernando Ugarte, Jesús Ciriza, Dean Li, Marcos E García-Ojeda, Lindsay Hinck, E Camilla Forsberg. Cell Stem Cell 2011
Stephanie Smith-Berdan, Andrew Nguyen, Deena Hassanein, Matthew Zimmer, Fernando Ugarte, Jesús Ciriza, Dean Li, Marcos E García-Ojeda, Lindsay Hinck, E Camilla Forsberg. Cell Stem Cell 2011
10
Basic and therapeutic aspects of angiogenesis.
Michael Potente, Holger Gerhardt, Peter Carmeliet. Cell 2011
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Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.
K Wong, X R Ren, Y Z Huang, Y Xie, G Liu, H Saito, H Tang, L Wen, S M Brady-Kalnay, L Mei,[...]. Cell 2001
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10
SLIT2-mediated ROBO2 signaling restricts kidney induction to a single site.
Uta Grieshammer, Le Ma, Andrew S Plump, Fan Wang, Marc Tessier-Lavigne, Gail R Martin. Dev Cell 2004
Uta Grieshammer, Le Ma, Andrew S Plump, Fan Wang, Marc Tessier-Lavigne, Gail R Martin. Dev Cell 2004
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Netrin-4 inhibits angiogenesis via binding to neogenin and recruitment of Unc5B.
Esma Lejmi, Laurence Leconte, Sandrine Pédron-Mazoyer, Stanislas Ropert, William Raoul, Sophie Lavalette, Ilyes Bouras, Jean-Guillaume Feron, Martine Maitre-Boube, Franck Assayag,[...]. Proc Natl Acad Sci U S A 2008
Esma Lejmi, Laurence Leconte, Sandrine Pédron-Mazoyer, Stanislas Ropert, William Raoul, Sophie Lavalette, Ilyes Bouras, Jean-Guillaume Feron, Martine Maitre-Boube, Franck Assayag,[...]. Proc Natl Acad Sci U S A 2008
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Suppression of Slit2/Robo1 mediated HUVEC migration by Robo4.
Satoshi Enomoto, Kenichi Mitsui, Takeshi Kawamura, Hiroko Iwanari, Kenji Daigo, Keiko Horiuchi, Takashi Minami, Tatsuhiko Kodama, Takao Hamakubo. Biochem Biophys Res Commun 2016
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Slits and Roundabouts in cancer, tumour angiogenesis and endothelial cell migration.
John A Legg, John M J Herbert, Patricia Clissold, Roy Bicknell. Angiogenesis 2008
John A Legg, John M J Herbert, Patricia Clissold, Roy Bicknell. Angiogenesis 2008
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Novel roles for Slits and netrins: axon guidance cues as anticancer targets?
Patrick Mehlen, Céline Delloye-Bourgeois, Alain Chédotal. Nat Rev Cancer 2011
Patrick Mehlen, Céline Delloye-Bourgeois, Alain Chédotal. Nat Rev Cancer 2011
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Identification and functional analysis of endothelial tip cell-enriched genes.
Raquel del Toro, Claudia Prahst, Thomas Mathivet, Geraldine Siegfried, Joshua S Kaminker, Bruno Larrivee, Christiane Breant, Antonio Duarte, Nobuyuki Takakura, Akiyoshi Fukamizu,[...]. Blood 2010
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FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neurons.
Satoru Yamagishi, Falko Hampel, Katsuhiko Hata, Daniel Del Toro, Manuela Schwark, Elena Kvachnina, Martin Bastmeyer, Toshihide Yamashita, Victor Tarabykin, Rüdiger Klein,[...]. EMBO J 2011
Satoru Yamagishi, Falko Hampel, Katsuhiko Hata, Daniel Del Toro, Manuela Schwark, Elena Kvachnina, Martin Bastmeyer, Toshihide Yamashita, Victor Tarabykin, Rüdiger Klein,[...]. EMBO J 2011
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Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis.
Mats Hellström, Li-Kun Phng, Jennifer J Hofmann, Elisabet Wallgard, Leigh Coultas, Per Lindblom, Jackelyn Alva, Ann-Katrin Nilsson, Linda Karlsson, Nicholas Gaiano,[...]. Nature 2007
Mats Hellström, Li-Kun Phng, Jennifer J Hofmann, Elisabet Wallgard, Leigh Coultas, Per Lindblom, Jackelyn Alva, Ann-Katrin Nilsson, Linda Karlsson, Nicholas Gaiano,[...]. Nature 2007
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Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis.
Yingdi Wang, Masanori Nakayama, Mara E Pitulescu, Tim S Schmidt, Magdalena L Bochenek, Akira Sakakibara, Susanne Adams, Alice Davy, Urban Deutsch, Urs Lüthi,[...]. Nature 2010
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Endothelial Robo4 suppresses breast cancer growth and metastasis through regulation of tumor angiogenesis.
Helong Zhao, Dinesh K Ahirwar, Steve Oghumu, Tasha Wilkie, Catherine A Powell, Mohd W Nasser, Abhay R Satoskar, Dean Y Li, Ramesh K Ganju. Mol Oncol 2016
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Regulation of commissural axon pathfinding by slit and its Robo receptors.
Barry J Dickson, Giorgio F Gilestro. Annu Rev Cell Dev Biol 2006
Barry J Dickson, Giorgio F Gilestro. Annu Rev Cell Dev Biol 2006
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The Adam family metalloprotease Kuzbanian regulates the cleavage of the roundabout receptor to control axon repulsion at the midline.
Hope A Coleman, Juan-Pablo Labrador, Rebecca K Chance, Greg J Bashaw. Development 2010
Hope A Coleman, Juan-Pablo Labrador, Rebecca K Chance, Greg J Bashaw. Development 2010
13
Molecular regulation of angiogenesis and lymphangiogenesis.
Ralf H Adams, Kari Alitalo. Nat Rev Mol Cell Biol 2007
Ralf H Adams, Kari Alitalo. Nat Rev Mol Cell Biol 2007
8
8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.