A citation-based method for searching scientific literature

Jia Zou, Liang Zhou, Xiao-Xia Du, Yifei Ji, Jia Xu, Junlong Tian, Wanxiang Jiang, Yi Zou, Shouyang Yu, Lingxue Gan, Maowen Luo, Qiaona Yang, Yiyuan Cui, Wanchun Yang, Xiaoqiang Xia, Mina Chen, Xia Zhao, Ying Shen, Po Yu Chen, Paul F Worley, Bo Xiao. Dev Cell 2011
Times Cited: 90







List of co-cited articles
776 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


mTOR signaling in growth control and disease.
Mathieu Laplante, David M Sabatini. Cell 2012
23

Rheb is essential for murine development.
Susanna M I Goorden, Marianne Hoogeveen-Westerveld, Caroline Cheng, Geeske M van Woerden, Melika Mozaffari, Laura Post, Henricus J Duckers, Mark Nellist, Ype Elgersma. Mol Cell Biol 2011
52
36

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling.
Ken Inoki, Yong Li, Tian Xu, Kun-Liang Guan. Genes Dev 2003
18

rheb, a growth factor- and synaptic activity-regulated gene, encodes a novel Ras-related protein.
K Yamagata, L K Sanders, W E Kaufmann, W Yee, C A Barnes, D Nathans, P F Worley. J Biol Chem 1994
221
17

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB.
Dos D Sarbassov, Siraj M Ali, Shomit Sengupta, Joon-Ho Sheen, Peggy P Hsu, Alex F Bagley, Andrew L Markhard, David M Sabatini. Mol Cell 2006
15

Activation of the mammalian target of rapamycin (mTOR) is essential for oligodendrocyte differentiation.
William A Tyler, Nitish Gangoli, Pradeepa Gokina, Haesun A Kim, Matthew Covey, Steven W Levison, Teresa L Wood. J Neurosci 2009
177
15

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.
D D Sarbassov, David A Guertin, Siraj M Ali, David M Sabatini. Science 2005
15

mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.
Timothy R Peterson, Shomit S Sengupta, Thurl E Harris, Anne E Carmack, Seong A Kang, Eric Balderas, David A Guertin, Katherine L Madden, Anne E Carpenter, Brian N Finck,[...]. Cell 2011
669
15

Rheb binds and regulates the mTOR kinase.
Xiaomeng Long, Yenshou Lin, Sara Ortiz-Vega, Kazuyoshi Yonezawa, Joseph Avruch. Curr Biol 2005
660
15

Rheb promotes cell growth as a component of the insulin/TOR signalling network.
Leslie J Saucedo, Xinsheng Gao, Dominic A Chiarelli, Ling Li, Duoija Pan, Bruce A Edgar. Nat Cell Biol 2003
480
15

Akt signals through the mammalian target of rapamycin pathway to regulate CNS myelination.
S Priyadarshini Narayanan, Ana I Flores, Feng Wang, Wendy B Macklin. J Neurosci 2009
221
14

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.
Yasemin Sancak, Timothy R Peterson, Yoav D Shaul, Robert A Lindquist, Carson C Thoreen, Liron Bar-Peled, David M Sabatini. Science 2008
14

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.
Yasemin Sancak, Liron Bar-Peled, Roberto Zoncu, Andrew L Markhard, Shigeyuki Nada, David M Sabatini. Cell 2010
14


mTOR: from growth signal integration to cancer, diabetes and ageing.
Roberto Zoncu, Alejo Efeyan, David M Sabatini. Nat Rev Mol Cell Biol 2011
13

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase.
Yasemin Sancak, Carson C Thoreen, Timothy R Peterson, Robert A Lindquist, Seong A Kang, Eric Spooner, Steven A Carr, David M Sabatini. Mol Cell 2007
862
13


Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.
David A Guertin, Deanna M Stevens, Carson C Thoreen, Aurora A Burds, Nada Y Kalaany, Jason Moffat, Michael Brown, Kevin J Fitzgerald, David M Sabatini. Dev Cell 2006
13

The Rheb family of GTP-binding proteins.
Paul-Joseph Aspuria, Fuyuhiko Tamanoi. Cell Signal 2004
151
12

Regulation of TORC1 by Rag GTPases in nutrient response.
Eunjung Kim, Pankuri Goraksha-Hicks, Li Li, Thomas P Neufeld, Kun-Liang Guan. Nat Cell Biol 2008
859
12

The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins.
Laura S Harrington, Greg M Findlay, Alex Gray, Tatiana Tolkacheva, Simon Wigfield, Heike Rebholz, Jill Barnett, Nick R Leslie, Susan Cheng, Peter R Shepherd,[...]. J Cell Biol 2004
816
12

Non-canonical functions of the tuberous sclerosis complex-Rheb signalling axis.
Nicole A Neuman, Elizabeth Petri Henske. EMBO Mol Med 2011
58
17

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery.
Do-Hyung Kim, D D Sarbassov, Siraj M Ali, Jessie E King, Robert R Latek, Hediye Erdjument-Bromage, Paul Tempst, David M Sabatini. Cell 2002
11

Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40.
Emilie Vander Haar, Seong-Il Lee, Sricharan Bandhakavi, Timothy J Griffin, Do-Hyung Kim. Nat Cell Biol 2007
815
11

TOR signaling in growth and metabolism.
Stephan Wullschleger, Robbie Loewith, Michael N Hall. Cell 2006
11

Constitutively active Akt induces enhanced myelination in the CNS.
Ana I Flores, S Priyadarshini Narayanan, Emily N Morse, H Elizabeth Shick, Xinghua Yin, Grahame Kidd, Robin L Avila, Daniel A Kirschner, Wendy B Macklin. J Neurosci 2008
250
11

Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2.
Attila Garami, Fried J T Zwartkruis, Takahiro Nobukuni, Manel Joaquin, Marta Roccio, Hugo Stocker, Sara C Kozma, Ernst Hafen, Johannes L Bos, George Thomas. Mol Cell 2003
750
11

Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins.
Yong Zhang, Xinsheng Gao, Leslie J Saucedo, Binggen Ru, Bruce A Edgar, Duojia Pan. Nat Cell Biol 2003
669
11

Activation of a metabolic gene regulatory network downstream of mTOR complex 1.
Katrin Düvel, Jessica L Yecies, Suchithra Menon, Pichai Raman, Alex I Lipovsky, Amanda L Souza, Ellen Triantafellow, Qicheng Ma, Regina Gorski, Stephen Cleaver,[...]. Mol Cell 2010
11

Rheb is an essential regulator of S6K in controlling cell growth in Drosophila.
Hugo Stocker, Thomas Radimerski, Benno Schindelholz, Franz Wittwer, Priyanka Belawat, Pierre Daram, Sebastian Breuer, George Thomas, Ernst Hafen. Nat Cell Biol 2003
389
10

Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination.
Sandra Goebbels, Jan H Oltrogge, Robert Kemper, Ingo Heilmann, Ingo Bormuth, Susanne Wolfer, Sven P Wichert, Wiebke Möbius, Xin Liu, Corinna Lappe-Siefke,[...]. J Neurosci 2010
216
10

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.
Estela Jacinto, Robbie Loewith, Anja Schmidt, Shuo Lin, Markus A Rüegg, Alan Hall, Michael N Hall. Nat Cell Biol 2004
10

Drosophila Rheb GTPase is required for cell cycle progression and cell growth.
Parthive H Patel, Nitika Thapar, Lea Guo, Monica Martinez, John Maris, Chia-Ling Gau, Judith A Lengyel, Fuyuhiko Tamanoi. J Cell Sci 2003
119
10

SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity.
Estela Jacinto, Valeria Facchinetti, Dou Liu, Nelyn Soto, Shiniu Wei, Sung Yun Jung, Qiaojia Huang, Jun Qin, Bing Su. Cell 2006
10

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.
Greg M Delgoffe, Kristen N Pollizzi, Adam T Waickman, Emily Heikamp, David J Meyers, Maureen R Horton, Bo Xiao, Paul F Worley, Jonathan D Powell. Nat Immunol 2011
715
8

mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex.
John T Cunningham, Joseph T Rodgers, Daniel H Arlow, Francisca Vazquez, Vamsi K Mootha, Pere Puigserver. Nature 2007
926
8

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton.
D D Sarbassov, Siraj M Ali, Do-Hyung Kim, David A Guertin, Robert R Latek, Hediye Erdjument-Bromage, Paul Tempst, David M Sabatini. Curr Biol 2004
8

The TSC1-TSC2 complex is required for proper activation of mTOR complex 2.
Jingxiang Huang, Christian C Dibble, Mika Matsuzaki, Brendan D Manning. Mol Cell Biol 2008
354
8

The TSC1-TSC2 complex: a molecular switchboard controlling cell growth.
Jingxiang Huang, Brendan D Manning. Biochem J 2008
779
8

SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth.
Thomas Porstmann, Claudio R Santos, Beatrice Griffiths, Megan Cully, Mary Wu, Sally Leevers, John R Griffiths, Yuen-Li Chung, Almut Schulze. Cell Metab 2008
772
8

AMPK phosphorylation of raptor mediates a metabolic checkpoint.
Dana M Gwinn, David B Shackelford, Daniel F Egan, Maria M Mihaylova, Annabelle Mery, Debbie S Vasquez, Benjamin E Turk, Reuben J Shaw. Mol Cell 2008
8

TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1.
Christian C Dibble, Winfried Elis, Suchithra Menon, Wei Qin, Justin Klekota, John M Asara, Peter M Finan, David J Kwiatkowski, Leon O Murphy, Brendan D Manning. Mol Cell 2012
368
8


TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling.
Ken Inoki, Yong Li, Tianquan Zhu, Jun Wu, Kun-Liang Guan. Nat Cell Biol 2002
8

A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival.
Lynsey Meikle, Delia M Talos, Hiroaki Onda, Kristen Pollizzi, Alexander Rotenberg, Mustafa Sahin, Frances E Jensen, David J Kwiatkowski. J Neurosci 2007
309
8

Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome.
Suchithra Menon, Christian C Dibble, George Talbott, Gerta Hoxhaj, Alexander J Valvezan, Hidenori Takahashi, Lewis C Cantley, Brendan D Manning. Cell 2014
438
8

Conditional ablation of raptor or rictor has differential impact on oligodendrocyte differentiation and CNS myelination.
Kathryn K Bercury, JinXiang Dai, Hilary H Sachs, Jared T Ahrendsen, Teresa L Wood, Wendy B Macklin. J Neurosci 2014
87
9

Mammalian target of rapamycin promotes oligodendrocyte differentiation, initiation and extent of CNS myelination.
Stacey E Wahl, Lauren E McLane, Kathryn K Bercury, Wendy B Macklin, Teresa L Wood. J Neurosci 2014
113
8

Oligodendrocyte precursor cell-intrinsic effect of Rheb1 controls differentiation and mediates mTORC1-dependent myelination in brain.
Yi Zou, Wanxiang Jiang, Jianqing Wang, Zhongping Li, Junyan Zhang, Jicheng Bu, Jia Zou, Liang Zhou, Shouyang Yu, Yiyuan Cui,[...]. J Neurosci 2014
37
21

Rheb fills a GAP between TSC and TOR.
Brendan D Manning, Lewis C Cantley. Trends Biochem Sci 2003
372
7


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.