A citation-based method for searching scientific literature

Rob A Cairns, Isaac S Harris, Tak W Mak. Nat Rev Cancer 2011
Times Cited: 3093







List of co-cited articles
426 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
19

Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
17

The Emerging Hallmarks of Cancer Metabolism.
Natalya N Pavlova, Craig B Thompson. Cell Metab 2016
13

Understanding the Intersections between Metabolism and Cancer Biology.
Matthew G Vander Heiden, Ralph J DeBerardinis. Cell 2017
908
12

Fundamentals of cancer metabolism.
Ralph J DeBerardinis, Navdeep S Chandel. Sci Adv 2016
12

On the origin of cancer cells.
O WARBURG. Science 1956
11

Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.
Hyuna Sung, Jacques Ferlay, Rebecca L Siegel, Mathieu Laversanne, Isabelle Soerjomataram, Ahmedin Jemal, Freddie Bray. CA Cancer J Clin 2021
8

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation.
Ralph J DeBerardinis, Julian J Lum, Georgia Hatzivassiliou, Craig B Thompson. Cell Metab 2008
7

Modulation of oxidative stress as an anticancer strategy.
Chiara Gorrini, Isaac S Harris, Tak W Mak. Nat Rev Drug Discov 2013
7

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
7

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
Dunyaporn Trachootham, Jerome Alexandre, Peng Huang. Nat Rev Drug Discov 2009
7

Cancer cell metabolism: Warburg and beyond.
Peggy P Hsu, David M Sabatini. Cell 2008
5

THE METABOLISM OF TUMORS IN THE BODY.
O Warburg, F Wind, E Negelein. J Gen Physiol 1927
5



From Krebs to clinic: glutamine metabolism to cancer therapy.
Brian J Altman, Zachary E Stine, Chi V Dang. Nat Rev Cancer 2016
732
5

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.
Richard Possemato, Kevin M Marks, Yoav D Shaul, Michael E Pacold, Dohoon Kim, Kıvanç Birsoy, Shalini Sethumadhavan, Hin-Koon Woo, Hyun G Jang, Abhishek K Jha,[...]. Nature 2011
994
5

Oxidative stress inhibits distant metastasis by human melanoma cells.
Elena Piskounova, Michalis Agathocleous, Malea M Murphy, Zeping Hu, Sara E Huddlestun, Zhiyu Zhao, A Marilyn Leitch, Timothy M Johnson, Ralph J DeBerardinis, Sean J Morrison. Nature 2015
616
5

The Warburg Effect: How Does it Benefit Cancer Cells?
Maria V Liberti, Jason W Locasale. Trends Biochem Sci 2016
5

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism.
Ping Gao, Irina Tchernyshyov, Tsung-Cheng Chang, Yun-Sil Lee, Kayoko Kita, Takafumi Ochi, Karen I Zeller, Angelo M De Marzo, Jennifer E Van Eyk, Joshua T Mendell,[...]. Nature 2009
4

BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells.
Eleni D Lagadinou, Alexander Sach, Kevin Callahan, Randall M Rossi, Sarah J Neering, Mohammad Minhajuddin, John M Ashton, Shanshan Pei, Valerie Grose, Kristen M O'Dwyer,[...]. Cell Stem Cell 2013
706
4

mTOR: from growth signal integration to cancer, diabetes and ageing.
Roberto Zoncu, Alejo Efeyan, David M Sabatini. Nat Rev Mol Cell Biol 2011
4


Autophagy and Tumor Metabolism.
Alec C Kimmelman, Eileen White. Cell Metab 2017
412
4

PKM2, cancer metabolism, and the road ahead.
Talya L Dayton, Tyler Jacks, Matthew G Vander Heiden. EMBO Rep 2016
236
4

Metabolic pathways promoting cancer cell survival and growth.
Lindsey K Boroughs, Ralph J DeBerardinis. Nat Cell Biol 2015
712
4

Altered metabolite levels in cancer: implications for tumour biology and cancer therapy.
Lucas B Sullivan, Dan Y Gui, Matthew G Vander Heiden. Nat Rev Cancer 2016
206
4

Aerobic glycolysis: meeting the metabolic requirements of cell proliferation.
Sophia Y Lunt, Matthew G Vander Heiden. Annu Rev Cell Dev Biol 2011
4

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.
Jaekyoung Son, Costas A Lyssiotis, Haoqiang Ying, Xiaoxu Wang, Sujun Hua, Matteo Ligorio, Rushika M Perera, Cristina R Ferrone, Edouard Mullarky, Ng Shyh-Chang,[...]. Nature 2013
4

Serine and glycine metabolism in cancer.
Ivano Amelio, Francesca Cutruzzolá, Alexey Antonov, Massimiliano Agostini, Gerry Melino. Trends Biochem Sci 2014
492
4

Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells.
Anne Le, Andrew N Lane, Max Hamaker, Sminu Bose, Arvin Gouw, Joseph Barbi, Takashi Tsukamoto, Camilio J Rojas, Barbara S Slusher, Haixia Zhang,[...]. Cell Metab 2012
683
4

Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition.
Nathalie Jacque, Anne Marie Ronchetti, Clément Larrue, Godelieve Meunier, Rudy Birsen, Lise Willems, Estelle Saland, Justine Decroocq, Thiago Trovati Maciel, Mireille Lambert,[...]. Blood 2015
213
4

Ferroptosis: an iron-dependent form of nonapoptotic cell death.
Scott J Dixon, Kathryn M Lemberg, Michael R Lamprecht, Rachid Skouta, Eleina M Zaitsev, Caroline E Gleason, Darpan N Patel, Andras J Bauer, Alexandra M Cantley, Wan Seok Yang,[...]. Cell 2012
4

Mitochondrial metabolism and cancer.
Paolo Ettore Porporato, Nicoletta Filigheddu, José Manuel Bravo-San Pedro, Guido Kroemer, Lorenzo Galluzzi. Cell Res 2018
409
4

Why do cancers have high aerobic glycolysis?
Robert A Gatenby, Robert J Gillies. Nat Rev Cancer 2004
4


Otto Warburg's contributions to current concepts of cancer metabolism.
Willem H Koppenol, Patricia L Bounds, Chi V Dang. Nat Rev Cancer 2011
4

Reactive Oxygen Species (ROS)-Based Nanomedicine.
Bowen Yang, Yu Chen, Jianlin Shi. Chem Rev 2019
487
4

Cancer statistics, 2020.
Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal. CA Cancer J Clin 2020
4

Cancer metabolism: fatty acid oxidation in the limelight.
Arkaitz Carracedo, Lewis C Cantley, Pier Paolo Pandolfi. Nat Rev Cancer 2013
661
3


PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis.
Valerie S LeBleu, Joyce T O'Connell, Karina N Gonzalez Herrera, Harriet Wikman, Klaus Pantel, Marcia C Haigis, Fernanda Machado de Carvalho, Aline Damascena, Ludmilla Thome Domingos Chinen, Rafael M Rocha,[...]. Nat Cell Biol 2014
728
3

Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells.
P M Tedeschi, E K Markert, M Gounder, H Lin, D Dvorzhinski, S C Dolfi, L L-Y Chan, J Qiu, R S DiPaola, K M Hirshfield,[...]. Cell Death Dis 2013
164
3

Acetate dependence of tumors.
Sarah A Comerford, Zhiguang Huang, Xinlin Du, Yun Wang, Ling Cai, Agnes K Witkiewicz, Holly Walters, Mohammed N Tantawy, Allie Fu, H Charles Manning,[...]. Cell 2014
341
3

Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma.
Fabienne Guillaumond, Ghislain Bidaut, Mehdi Ouaissi, Stéphane Servais, Victoire Gouirand, Orianne Olivares, Sophie Lac, Laurence Borge, Julie Roques, Odile Gayet,[...]. Proc Natl Acad Sci U S A 2015
191
3

Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance.
Antonina V Kurtova, Jing Xiao, Qianxing Mo, Senthil Pazhanisamy, Ross Krasnow, Seth P Lerner, Fengju Chen, Terrence T Roh, Erica Lay, Philip Levy Ho,[...]. Nature 2015
353
3

Glutamine addiction: a new therapeutic target in cancer.
David R Wise, Craig B Thompson. Trends Biochem Sci 2010
3

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.
Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan. Nat Cell Biol 2011
3

Glutaminolysis: A Hallmark of Cancer Metabolism.
Lifeng Yang, Sriram Venneti, Deepak Nagrath. Annu Rev Biomed Eng 2017
230
3

mTOR Signaling in Growth, Metabolism, and Disease.
Robert A Saxton, David M Sabatini. Cell 2017
3


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.