Nanxin Li, Rong-Jian Liu, Jason M Dwyer, Mounira Banasr, Boyoung Lee, Hyeon Son, Xiao-Yuan Li, George Aghajanian, Ronald S Duman. Biol Psychiatry 2011
Times Cited: 711
Times Cited: 711
Times Cited
Times Co-cited
Similarity
mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists.
Nanxin Li, Boyoung Lee, Rong-Jian Liu, Mounira Banasr, Jason M Dwyer, Masaaki Iwata, Xiao-Yuan Li, George Aghajanian, Ronald S Duman. Science 2010
Nanxin Li, Boyoung Lee, Rong-Jian Liu, Mounira Banasr, Jason M Dwyer, Masaaki Iwata, Xiao-Yuan Li, George Aghajanian, Ronald S Duman. Science 2010
53
Antidepressant effects of ketamine in depressed patients.
R M Berman, A Cappiello, A Anand, D A Oren, G R Heninger, D S Charney, J H Krystal. Biol Psychiatry 2000
R M Berman, A Cappiello, A Anand, D A Oren, G R Heninger, D S Charney, J H Krystal. Biol Psychiatry 2000
41
A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression.
Carlos A Zarate, Jaskaran B Singh, Paul J Carlson, Nancy E Brutsche, Rezvan Ameli, David A Luckenbaugh, Dennis S Charney, Husseini K Manji. Arch Gen Psychiatry 2006
Carlos A Zarate, Jaskaran B Singh, Paul J Carlson, Nancy E Brutsche, Rezvan Ameli, David A Luckenbaugh, Dennis S Charney, Husseini K Manji. Arch Gen Psychiatry 2006
36
NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses.
Anita E Autry, Megumi Adachi, Elena Nosyreva, Elisa S Na, Maarten F Los, Peng-fei Cheng, Ege T Kavalali, Lisa M Monteggia. Nature 2011
Anita E Autry, Megumi Adachi, Elena Nosyreva, Elisa S Na, Maarten F Los, Peng-fei Cheng, Ege T Kavalali, Lisa M Monteggia. Nature 2011
32
NMDAR inhibition-independent antidepressant actions of ketamine metabolites.
Panos Zanos, Ruin Moaddel, Patrick J Morris, Polymnia Georgiou, Jonathan Fischell, Greg I Elmer, Manickavasagom Alkondon, Peixiong Yuan, Heather J Pribut, Nagendra S Singh,[...]. Nature 2016
Panos Zanos, Ruin Moaddel, Patrick J Morris, Polymnia Georgiou, Jonathan Fischell, Greg I Elmer, Manickavasagom Alkondon, Peixiong Yuan, Heather J Pribut, Nagendra S Singh,[...]. Nature 2016
24
Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants.
Ronald S Duman, George K Aghajanian, Gerard Sanacora, John H Krystal. Nat Med 2016
Ronald S Duman, George K Aghajanian, Gerard Sanacora, John H Krystal. Nat Med 2016
22
Synaptic dysfunction in depression: potential therapeutic targets.
Ronald S Duman, George K Aghajanian. Science 2012
Ronald S Duman, George K Aghajanian. Science 2012
20
Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors.
Sungho Maeng, Carlos A Zarate, Jing Du, Robert J Schloesser, Joseph McCammon, Guang Chen, Husseini K Manji. Biol Psychiatry 2008
Sungho Maeng, Carlos A Zarate, Jing Du, Robert J Schloesser, Joseph McCammon, Guang Chen, Husseini K Manji. Biol Psychiatry 2008
20
Decreased expression of synapse-related genes and loss of synapses in major depressive disorder.
Hyo Jung Kang, Bhavya Voleti, Tibor Hajszan, Grazyna Rajkowska, Craig A Stockmeier, Pawel Licznerski, Ashley Lepack, Mahesh S Majik, Lak Shin Jeong, Mounira Banasr,[...]. Nat Med 2012
Hyo Jung Kang, Bhavya Voleti, Tibor Hajszan, Grazyna Rajkowska, Craig A Stockmeier, Pawel Licznerski, Ashley Lepack, Mahesh S Majik, Lak Shin Jeong, Mounira Banasr,[...]. Nat Med 2012
18
Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation.
R N Moda-Sava, M H Murdock, P K Parekh, R N Fetcho, B S Huang, T N Huynh, J Witztum, D C Shaver, D L Rosenthal, E J Alway,[...]. Science 2019
R N Moda-Sava, M H Murdock, P K Parekh, R N Fetcho, B S Huang, T N Huynh, J Witztum, D C Shaver, D L Rosenthal, E J Alway,[...]. Science 2019
17
Ketamine-induced antidepressant effects are associated with AMPA receptors-mediated upregulation of mTOR and BDNF in rat hippocampus and prefrontal cortex.
W Zhou, N Wang, C Yang, X-M Li, Z-Q Zhou, J-J Yang. Eur Psychiatry 2014
W Zhou, N Wang, C Yang, X-M Li, Z-Q Zhou, J-J Yang. Eur Psychiatry 2014
16
Optogenetic stimulation of infralimbic PFC reproduces ketamine's rapid and sustained antidepressant actions.
Manabu Fuchikami, Alexandra Thomas, Rongjian Liu, Eric S Wohleb, Benjamin B Land, Ralph J DiLeone, George K Aghajanian, Ronald S Duman. Proc Natl Acad Sci U S A 2015
Manabu Fuchikami, Alexandra Thomas, Rongjian Liu, Eric S Wohleb, Benjamin B Land, Ralph J DiLeone, George K Aghajanian, Ronald S Duman. Proc Natl Acad Sci U S A 2015
15
BDNF release is required for the behavioral actions of ketamine.
Ashley E Lepack, Manabu Fuchikami, Jason M Dwyer, Mounira Banasr, Ronald S Duman. Int J Neuropsychopharmacol 2014
Ashley E Lepack, Manabu Fuchikami, Jason M Dwyer, Mounira Banasr, Ronald S Duman. Int J Neuropsychopharmacol 2014
15
Modulation of the antidepressant effects of ketamine by the mTORC1 inhibitor rapamycin.
Chadi G Abdallah, Lynnette A Averill, Ralitza Gueorguieva, Selin Goktas, Prerana Purohit, Mohini Ranganathan, Mohamed Sherif, Kyung-Heup Ahn, Deepak Cyril D'Souza, Richard Formica,[...]. Neuropsychopharmacology 2020
Chadi G Abdallah, Lynnette A Averill, Ralitza Gueorguieva, Selin Goktas, Prerana Purohit, Mohini Ranganathan, Mohamed Sherif, Kyung-Heup Ahn, Deepak Cyril D'Souza, Richard Formica,[...]. Neuropsychopharmacology 2020
27
R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects.
C Yang, Y Shirayama, J-c Zhang, Q Ren, W Yao, M Ma, C Dong, K Hashimoto. Transl Psychiatry 2015
C Yang, Y Shirayama, J-c Zhang, Q Ren, W Yao, M Ma, C Dong, K Hashimoto. Transl Psychiatry 2015
14
Involvement of AMPA receptor in both the rapid and sustained antidepressant-like effects of ketamine in animal models of depression.
Hiroyuki Koike, Michihiko Iijima, Shigeyuki Chaki. Behav Brain Res 2011
Hiroyuki Koike, Michihiko Iijima, Shigeyuki Chaki. Behav Brain Res 2011
13
The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission.
Maurizio Popoli, Zhen Yan, Bruce S McEwen, Gerard Sanacora. Nat Rev Neurosci 2011
Maurizio Popoli, Zhen Yan, Bruce S McEwen, Gerard Sanacora. Nat Rev Neurosci 2011
13
Effects of intravenous ketamine on explicit and implicit measures of suicidality in treatment-resistant depression.
Rebecca B Price, Matthew K Nock, Dennis S Charney, Sanjay J Mathew. Biol Psychiatry 2009
Rebecca B Price, Matthew K Nock, Dennis S Charney, Sanjay J Mathew. Biol Psychiatry 2009
13
Disinhibition of CA1 pyramidal cells by low-dose ketamine and other antagonists with rapid antidepressant efficacy.
Allie J Widman, Lori L McMahon. Proc Natl Acad Sci U S A 2018
Allie J Widman, Lori L McMahon. Proc Natl Acad Sci U S A 2018
14
Ketamine blocks bursting in the lateral habenula to rapidly relieve depression.
Yan Yang, Yihui Cui, Kangning Sang, Yiyan Dong, Zheyi Ni, Shuangshuang Ma, Hailan Hu. Nature 2018
Yan Yang, Yihui Cui, Kangning Sang, Yiyan Dong, Zheyi Ni, Shuangshuang Ma, Hailan Hu. Nature 2018
13
Brain-derived neurotrophic factor Val66Met allele impairs basal and ketamine-stimulated synaptogenesis in prefrontal cortex.
Rong-Jian Liu, Francis S Lee, Xiao-Yuan Li, Francis Bambico, Ronald S Duman, George K Aghajanian. Biol Psychiatry 2012
Rong-Jian Liu, Francis S Lee, Xiao-Yuan Li, Francis Bambico, Ronald S Duman, George K Aghajanian. Biol Psychiatry 2012
12
(2R,6R)-hydroxynorketamine exerts mGlu2 receptor-dependent antidepressant actions.
Panos Zanos, Jaclyn N Highland, Brent W Stewart, Polymnia Georgiou, Carleigh E Jenne, Jacqueline Lovett, Patrick J Morris, Craig J Thomas, Ruin Moaddel, Carlos A Zarate,[...]. Proc Natl Acad Sci U S A 2019
Panos Zanos, Jaclyn N Highland, Brent W Stewart, Polymnia Georgiou, Carleigh E Jenne, Jacqueline Lovett, Patrick J Morris, Craig J Thomas, Ruin Moaddel, Carlos A Zarate,[...]. Proc Natl Acad Sci U S A 2019
18
Ketamine: A Paradigm Shift for Depression Research and Treatment.
John H Krystal, Chadi G Abdallah, Gerard Sanacora, Dennis S Charney, Ronald S Duman. Neuron 2019
John H Krystal, Chadi G Abdallah, Gerard Sanacora, Dennis S Charney, Ronald S Duman. Neuron 2019
12
A neurotrophic model for stress-related mood disorders.
Ronald S Duman, Lisa M Monteggia. Biol Psychiatry 2006
Ronald S Duman, Lisa M Monteggia. Biol Psychiatry 2006
12
Altered expression of synapse and glutamate related genes in post-mortem hippocampus of depressed subjects.
Vanja Duric, Mounira Banasr, Craig A Stockmeier, Arthur A Simen, Samuel S Newton, James C Overholser, George J Jurjus, Lesa Dieter, Ronald S Duman. Int J Neuropsychopharmacol 2013
Vanja Duric, Mounira Banasr, Craig A Stockmeier, Arthur A Simen, Samuel S Newton, James C Overholser, George J Jurjus, Lesa Dieter, Ronald S Duman. Int J Neuropsychopharmacol 2013
12
GABA interneurons are the cellular trigger for ketamine's rapid antidepressant actions.
Danielle M Gerhard, Santosh Pothula, Rong-Jian Liu, Min Wu, Xiao-Yuan Li, Matthew J Girgenti, Seth R Taylor, Catharine H Duman, Eric Delpire, Marina Picciotto,[...]. J Clin Invest 2020
Danielle M Gerhard, Santosh Pothula, Rong-Jian Liu, Min Wu, Xiao-Yuan Li, Matthew J Girgenti, Seth R Taylor, Catharine H Duman, Eric Delpire, Marina Picciotto,[...]. J Clin Invest 2020
14
GluN2B-containing NMDA receptors regulate depression-like behavior and are critical for the rapid antidepressant actions of ketamine.
Oliver H Miller, Lingling Yang, Chih-Chieh Wang, Elizabeth A Hargroder, Yihui Zhang, Eric Delpire, Benjamin J Hall. Elife 2014
Oliver H Miller, Lingling Yang, Chih-Chieh Wang, Elizabeth A Hargroder, Yihui Zhang, Eric Delpire, Benjamin J Hall. Elife 2014
12
Altered Connectivity in Depression: GABA and Glutamate Neurotransmitter Deficits and Reversal by Novel Treatments.
Ronald S Duman, Gerard Sanacora, John H Krystal. Neuron 2019
Ronald S Duman, Gerard Sanacora, John H Krystal. Neuron 2019
11
Activity-dependent brain-derived neurotrophic factor signaling is required for the antidepressant actions of (2R,6R)-hydroxynorketamine.
Kenichi Fukumoto, Manoela V Fogaça, Rong-Jian Liu, Catharine Duman, Taro Kato, Xiao-Yuan Li, Ronald S Duman. Proc Natl Acad Sci U S A 2019
Kenichi Fukumoto, Manoela V Fogaça, Rong-Jian Liu, Catharine Duman, Taro Kato, Xiao-Yuan Li, Ronald S Duman. Proc Natl Acad Sci U S A 2019
13
Ketamine and rapid-acting antidepressants: a window into a new neurobiology for mood disorder therapeutics.
Chadi G Abdallah, Gerard Sanacora, Ronald S Duman, John H Krystal. Annu Rev Med 2015
Chadi G Abdallah, Gerard Sanacora, Ronald S Duman, John H Krystal. Annu Rev Med 2015
11
11
Replication of ketamine's antidepressant efficacy in bipolar depression: a randomized controlled add-on trial.
Carlos A Zarate, Nancy E Brutsche, Lobna Ibrahim, Jose Franco-Chaves, Nancy Diazgranados, Anibal Cravchik, Jessica Selter, Craig A Marquardt, Victoria Liberty, David A Luckenbaugh. Biol Psychiatry 2012
Carlos A Zarate, Nancy E Brutsche, Lobna Ibrahim, Jose Franco-Chaves, Nancy Diazgranados, Anibal Cravchik, Jessica Selter, Craig A Marquardt, Victoria Liberty, David A Luckenbaugh. Biol Psychiatry 2012
11
NMDA receptor hypofunction produces opposite effects on prefrontal cortex interneurons and pyramidal neurons.
Houman Homayoun, Bita Moghaddam. J Neurosci 2007
Houman Homayoun, Bita Moghaddam. J Neurosci 2007
11
Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial.
James W Murrough, Dan V Iosifescu, Lee C Chang, Rayan K Al Jurdi, Charles E Green, Andrew M Perez, Syed Iqbal, Sarah Pillemer, Alexandra Foulkes, Asim Shah,[...]. Am J Psychiatry 2013
James W Murrough, Dan V Iosifescu, Lee C Chang, Rayan K Al Jurdi, Charles E Green, Andrew M Perez, Syed Iqbal, Sarah Pillemer, Alexandra Foulkes, Asim Shah,[...]. Am J Psychiatry 2013
11
Rapid resolution of suicidal ideation after a single infusion of an N-methyl-D-aspartate antagonist in patients with treatment-resistant major depressive disorder.
Nancy DiazGranados, Lobna A Ibrahim, Nancy E Brutsche, Rezvan Ameli, Ioline D Henter, David A Luckenbaugh, Rodrigo Machado-Vieira, Carlos A Zarate. J Clin Psychiatry 2010
Nancy DiazGranados, Lobna A Ibrahim, Nancy E Brutsche, Rezvan Ameli, Ioline D Henter, David A Luckenbaugh, Rodrigo Machado-Vieira, Carlos A Zarate. J Clin Psychiatry 2010
11
Rapid and longer-term antidepressant effects of repeated ketamine infusions in treatment-resistant major depression.
James W Murrough, Andrew M Perez, Sarah Pillemer, Jessica Stern, Michael K Parides, Marije aan het Rot, Katherine A Collins, Sanjay J Mathew, Dennis S Charney, Dan V Iosifescu. Biol Psychiatry 2013
James W Murrough, Andrew M Perez, Sarah Pillemer, Jessica Stern, Michael K Parides, Marije aan het Rot, Katherine A Collins, Sanjay J Mathew, Dennis S Charney, Dan V Iosifescu. Biol Psychiatry 2013
11
Transiently increased glutamate cycling in rat PFC is associated with rapid onset of antidepressant-like effects.
G M I Chowdhury, J Zhang, M Thomas, M Banasr, X Ma, B Pittman, L Bristow, E Schaeffer, R S Duman, D L Rothman,[...]. Mol Psychiatry 2017
G M I Chowdhury, J Zhang, M Thomas, M Banasr, X Ma, B Pittman, L Bristow, E Schaeffer, R S Duman, D L Rothman,[...]. Mol Psychiatry 2017
10
Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms.
Panos Zanos, Ruin Moaddel, Patrick J Morris, Lace M Riggs, Jaclyn N Highland, Polymnia Georgiou, Edna F R Pereira, Edson X Albuquerque, Craig J Thomas, Carlos A Zarate,[...]. Pharmacol Rev 2018
Panos Zanos, Ruin Moaddel, Patrick J Morris, Lace M Riggs, Jaclyn N Highland, Polymnia Georgiou, Edna F R Pereira, Edson X Albuquerque, Craig J Thomas, Carlos A Zarate,[...]. Pharmacol Rev 2018
10
GSK-3 inhibition potentiates the synaptogenic and antidepressant-like effects of subthreshold doses of ketamine.
Rong-Jian Liu, Manabu Fuchikami, Jason M Dwyer, Ashley E Lepack, Ronald S Duman, George K Aghajanian. Neuropsychopharmacology 2013
Rong-Jian Liu, Manabu Fuchikami, Jason M Dwyer, Ashley E Lepack, Ronald S Duman, George K Aghajanian. Neuropsychopharmacology 2013
10
Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice.
E Beurel, L Song, R S Jope. Mol Psychiatry 2011
E Beurel, L Song, R S Jope. Mol Psychiatry 2011
10
Ketamine Treatment and Global Brain Connectivity in Major Depression.
Chadi G Abdallah, Lynnette A Averill, Katherine A Collins, Paul Geha, Jaclyn Schwartz, Christopher Averill, Kaitlin E DeWilde, Edmund Wong, Alan Anticevic, Cheuk Y Tang,[...]. Neuropsychopharmacology 2017
Chadi G Abdallah, Lynnette A Averill, Katherine A Collins, Paul Geha, Jaclyn Schwartz, Christopher Averill, Kaitlin E DeWilde, Edmund Wong, Alan Anticevic, Cheuk Y Tang,[...]. Neuropsychopharmacology 2017
10
Ketamine and Other NMDA Antagonists: Early Clinical Trials and Possible Mechanisms in Depression.
D Jeffrey Newport, Linda L Carpenter, William M McDonald, James B Potash, Mauricio Tohen, Charles B Nemeroff. Am J Psychiatry 2015
D Jeffrey Newport, Linda L Carpenter, William M McDonald, James B Potash, Mauricio Tohen, Charles B Nemeroff. Am J Psychiatry 2015
10
The effects of ketamine on prefrontal glutamate neurotransmission in healthy and depressed subjects.
Chadi G Abdallah, Henk M De Feyter, Lynnette A Averill, Lihong Jiang, Christopher L Averill, Golam M I Chowdhury, Prerana Purohit, Robin A de Graaf, Irina Esterlis, Christoph Juchem,[...]. Neuropsychopharmacology 2018
Chadi G Abdallah, Henk M De Feyter, Lynnette A Averill, Lihong Jiang, Christopher L Averill, Golam M I Chowdhury, Prerana Purohit, Robin A de Graaf, Irina Esterlis, Christoph Juchem,[...]. Neuropsychopharmacology 2018
12
Antidepressant-relevant concentrations of the ketamine metabolite (2R,6R)-hydroxynorketamine do not block NMDA receptor function.
Eric W Lumsden, Timothy A Troppoli, Scott J Myers, Panos Zanos, Yasco Aracava, Jan Kehr, Jacqueline Lovett, Sukhan Kim, Fu-Hua Wang, Staffan Schmidt,[...]. Proc Natl Acad Sci U S A 2019
Eric W Lumsden, Timothy A Troppoli, Scott J Myers, Panos Zanos, Yasco Aracava, Jan Kehr, Jacqueline Lovett, Sukhan Kim, Fu-Hua Wang, Staffan Schmidt,[...]. Proc Natl Acad Sci U S A 2019
13
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Adriana Feder, Michael K Parides, James W Murrough, Andrew M Perez, Julia E Morgan, Shireen Saxena, Katherine Kirkwood, Marije Aan Het Rot, Kyle A B Lapidus, Le-Ben Wan,[...]. JAMA Psychiatry 2014
Adriana Feder, Michael K Parides, James W Murrough, Andrew M Perez, Julia E Morgan, Shireen Saxena, Katherine Kirkwood, Marije Aan Het Rot, Kyle A B Lapidus, Le-Ben Wan,[...]. JAMA Psychiatry 2014
9
Lower synaptic density is associated with depression severity and network alterations.
Sophie E Holmes, Dustin Scheinost, Sjoerd J Finnema, Mika Naganawa, Margaret T Davis, Nicole DellaGioia, Nabeel Nabulsi, David Matuskey, Gustavo A Angarita, Robert H Pietrzak,[...]. Nat Commun 2019
Sophie E Holmes, Dustin Scheinost, Sjoerd J Finnema, Mika Naganawa, Margaret T Davis, Nicole DellaGioia, Nabeel Nabulsi, David Matuskey, Gustavo A Angarita, Robert H Pietrzak,[...]. Nat Commun 2019
9
Common Neurotransmission Recruited in (R,S)-Ketamine and (2R,6R)-Hydroxynorketamine-Induced Sustained Antidepressant-like Effects.
Thu Ha Pham, Céline Defaix, Xiaoming Xu, Shi-Xian Deng, Nicolas Fabresse, Jean-Claude Alvarez, Donald W Landry, Rebecca A Brachman, Christine A Denny, Alain M Gardier. Biol Psychiatry 2018
Thu Ha Pham, Céline Defaix, Xiaoming Xu, Shi-Xian Deng, Nicolas Fabresse, Jean-Claude Alvarez, Donald W Landry, Rebecca A Brachman, Christine A Denny, Alain M Gardier. Biol Psychiatry 2018
12
The mTOR signaling pathway in the prefrontal cortex is compromised in major depressive disorder.
Courtney S Jernigan, Dharmendra B Goswami, Mark C Austin, Abiye H Iyo, Agata Chandran, Craig A Stockmeier, Beata Karolewicz. Prog Neuropsychopharmacol Biol Psychiatry 2011
Courtney S Jernigan, Dharmendra B Goswami, Mark C Austin, Abiye H Iyo, Agata Chandran, Craig A Stockmeier, Beata Karolewicz. Prog Neuropsychopharmacol Biol Psychiatry 2011
9
mTOR signaling: at the crossroads of plasticity, memory and disease.
Charles A Hoeffer, Eric Klann. Trends Neurosci 2010
Charles A Hoeffer, Eric Klann. Trends Neurosci 2010
9
Stress blunts serotonin- and hypocretin-evoked EPSCs in prefrontal cortex: role of corticosterone-mediated apical dendritic atrophy.
Rong-Jian Liu, George K Aghajanian. Proc Natl Acad Sci U S A 2008
Rong-Jian Liu, George K Aghajanian. Proc Natl Acad Sci U S A 2008
8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.