Wenjun Song, Jin Chen, Alejandra Petrilli, Geraldine Liot, Eva Klinglmayr, Yue Zhou, Patrick Poquiz, Jonathan Tjong, Mahmoud A Pouladi, Michael R Hayden, Eliezer Masliah, Mark Ellisman, Isabelle Rouiller, Robert Schwarzenbacher, Blaise Bossy, Guy Perkins, Ella Bossy-Wetzel. Nat Med 2011
Times Cited: 366
Times Cited: 366
Times Cited
Times Co-cited
Similarity
Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease.
Ulziibat P Shirendeb, Marcus J Calkins, Maria Manczak, Vishwanath Anekonda, Brett Dufour, Jodi L McBride, Peizhong Mao, P Hemachandra Reddy. Hum Mol Genet 2012
Ulziibat P Shirendeb, Marcus J Calkins, Maria Manczak, Vishwanath Anekonda, Brett Dufour, Jodi L McBride, Peizhong Mao, P Hemachandra Reddy. Hum Mol Genet 2012
38
Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage.
Ulziibat Shirendeb, Arubala P Reddy, Maria Manczak, Marcus J Calkins, Peizhong Mao, Danilo A Tagle, P Hemachandra Reddy. Hum Mol Genet 2011
Ulziibat Shirendeb, Arubala P Reddy, Maria Manczak, Marcus J Calkins, Peizhong Mao, Danilo A Tagle, P Hemachandra Reddy. Hum Mol Genet 2011
30
Inhibition of mitochondrial fragmentation diminishes Huntington's disease-associated neurodegeneration.
Xing Guo, Marie-Helene Disatnik, Marie Monbureau, Mehrdad Shamloo, Daria Mochly-Rosen, Xin Qi. J Clin Invest 2013
Xing Guo, Marie-Helene Disatnik, Marie Monbureau, Mehrdad Shamloo, Daria Mochly-Rosen, Xin Qi. J Clin Invest 2013
26
Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease.
Jinho Kim, Jennifer P Moody, Christina K Edgerly, Olivia L Bordiuk, Kerry Cormier, Karen Smith, M Flint Beal, Robert J Ferrante. Hum Mol Genet 2010
Jinho Kim, Jennifer P Moody, Christina K Edgerly, Olivia L Bordiuk, Kerry Cormier, Karen Smith, M Flint Beal, Robert J Ferrante. Hum Mol Genet 2010
26
25
Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.
Libin Cui, Hyunkyung Jeong, Fran Borovecki, Christopher N Parkhurst, Naoko Tanese, Dimitri Krainc. Cell 2006
Libin Cui, Hyunkyung Jeong, Fran Borovecki, Christopher N Parkhurst, Naoko Tanese, Dimitri Krainc. Cell 2006
24
Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuli.
Veronica Costa, Marta Giacomello, Roman Hudec, Raffaele Lopreiato, Gennady Ermak, Dmitri Lim, Walter Malorni, Kelvin J A Davies, Ernesto Carafoli, Luca Scorrano. EMBO Mol Med 2010
Veronica Costa, Marta Giacomello, Roman Hudec, Raffaele Lopreiato, Gennady Ermak, Dmitri Lim, Walter Malorni, Kelvin J A Davies, Ernesto Carafoli, Luca Scorrano. EMBO Mol Med 2010
23
N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking.
Adam L Orr, Shihua Li, Chuan-En Wang, He Li, Jianjun Wang, Juan Rong, Xingshun Xu, Pier Giorgio Mastroberardino, J Timothy Greenamyre, Xiao-Jiang Li. J Neurosci 2008
Adam L Orr, Shihua Li, Chuan-En Wang, He Li, Jianjun Wang, Juan Rong, Xingshun Xu, Pier Giorgio Mastroberardino, J Timothy Greenamyre, Xiao-Jiang Li. J Neurosci 2008
21
Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.
Alexander V Panov, Claire-Anne Gutekunst, Blair R Leavitt, Michael R Hayden, James R Burke, Warren J Strittmatter, J Timothy Greenamyre. Nat Neurosci 2002
Alexander V Panov, Claire-Anne Gutekunst, Blair R Leavitt, Michael R Hayden, James R Burke, Warren J Strittmatter, J Timothy Greenamyre. Nat Neurosci 2002
20
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage.
Maria Manczak, Marcus J Calkins, P Hemachandra Reddy. Hum Mol Genet 2011
Maria Manczak, Marcus J Calkins, P Hemachandra Reddy. Hum Mol Genet 2011
18
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease.
Xinglong Wang, Bo Su, Hyoung-gon Lee, Xinyi Li, George Perry, Mark A Smith, Xiongwei Zhu. J Neurosci 2009
Xinglong Wang, Bo Su, Hyoung-gon Lee, Xinyi Li, George Perry, Mark A Smith, Xiongwei Zhu. J Neurosci 2009
17
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy.
Gilad Twig, Alvaro Elorza, Anthony J A Molina, Hibo Mohamed, Jakob D Wikstrom, Gil Walzer, Linsey Stiles, Sarah E Haigh, Steve Katz, Guy Las,[...]. EMBO J 2008
Gilad Twig, Alvaro Elorza, Anthony J A Molina, Hibo Mohamed, Jakob D Wikstrom, Gil Walzer, Linsey Stiles, Sarah E Haigh, Steve Katz, Guy Las,[...]. EMBO J 2008
17
Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro.
Eugenia Trushina, Roy B Dyer, John D Badger, Daren Ure, Lars Eide, David D Tran, Brent T Vrieze, Valerie Legendre-Guillemin, Peter S McPherson, Bhaskar S Mandavilli,[...]. Mol Cell Biol 2004
Eugenia Trushina, Roy B Dyer, John D Badger, Daren Ure, Lars Eide, David D Tran, Brent T Vrieze, Valerie Legendre-Guillemin, Peter S McPherson, Bhaskar S Mandavilli,[...]. Mol Cell Biol 2004
16
16
Mitochondrial defect in Huntington's disease caudate nucleus.
M Gu, M T Gash, V M Mann, F Javoy-Agid, J M Cooper, A H Schapira. Ann Neurol 1996
M Gu, M T Gash, V M Mann, F Javoy-Agid, J M Cooper, A H Schapira. Ann Neurol 1996
15
Inhibition of mitochondrial protein import by mutant huntingtin.
Hiroko Yano, Sergei V Baranov, Oxana V Baranova, Jinho Kim, Yanchun Pan, Svitlana Yablonska, Diane L Carlisle, Robert J Ferrante, Albert H Kim, Robert M Friedlander. Nat Neurosci 2014
Hiroko Yano, Sergei V Baranov, Oxana V Baranova, Jinho Kim, Yanchun Pan, Svitlana Yablonska, Diane L Carlisle, Robert J Ferrante, Albert H Kim, Robert M Friedlander. Nat Neurosci 2014
15
VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease.
Xing Guo, XiaoYan Sun, Di Hu, Ya-Juan Wang, Hisashi Fujioka, Rajan Vyas, Sudha Chakrapani, Amit Umesh Joshi, Yu Luo, Daria Mochly-Rosen,[...]. Nat Commun 2016
Xing Guo, XiaoYan Sun, Di Hu, Ya-Juan Wang, Hisashi Fujioka, Rajan Vyas, Sudha Chakrapani, Amit Umesh Joshi, Yu Luo, Daria Mochly-Rosen,[...]. Nat Commun 2016
16
Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease.
Marta Martinez-Vicente, Zsolt Talloczy, Esther Wong, Guomei Tang, Hiroshi Koga, Susmita Kaushik, Rosa de Vries, Esperanza Arias, Spike Harris, David Sulzer,[...]. Nat Neurosci 2010
Marta Martinez-Vicente, Zsolt Talloczy, Esther Wong, Guomei Tang, Hiroshi Koga, Susmita Kaushik, Rosa de Vries, Esperanza Arias, Spike Harris, David Sulzer,[...]. Nat Neurosci 2010
15
Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia.
S E Browne, A C Bowling, U MacGarvey, M J Baik, S C Berger, M M Muqit, E D Bird, M F Beal. Ann Neurol 1997
S E Browne, A C Bowling, U MacGarvey, M J Baik, S C Berger, M M Muqit, E D Bird, M F Beal. Ann Neurol 1997
15
The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease.
Alicia M Pickrell, Richard J Youle. Neuron 2015
Alicia M Pickrell, Richard J Youle. Neuron 2015
14
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy.
Michael Lazarou, Danielle A Sliter, Lesley A Kane, Shireen A Sarraf, Chunxin Wang, Jonathon L Burman, Dionisia P Sideris, Adam I Fogel, Richard J Youle. Nature 2015
Michael Lazarou, Danielle A Sliter, Lesley A Kane, Shireen A Sarraf, Chunxin Wang, Jonathon L Burman, Dionisia P Sideris, Adam I Fogel, Richard J Youle. Nature 2015
14
S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury.
Dong-Hyung Cho, Tomohiro Nakamura, Jianguo Fang, Piotr Cieplak, Adam Godzik, Zezong Gu, Stuart A Lipton. Science 2009
Dong-Hyung Cho, Tomohiro Nakamura, Jianguo Fang, Piotr Cieplak, Adam Godzik, Zezong Gu, Stuart A Lipton. Science 2009
14
PINK1-induced mitophagy promotes neuroprotection in Huntington's disease.
B Khalil, N El Fissi, A Aouane, M-J Cabirol-Pol, T Rival, J-C Liévens. Cell Death Dis 2015
B Khalil, N El Fissi, A Aouane, M-J Cabirol-Pol, T Rival, J-C Liévens. Cell Death Dis 2015
14
A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity.
Xin Qi, Nir Qvit, Yu-Chin Su, Daria Mochly-Rosen. J Cell Sci 2013
Xin Qi, Nir Qvit, Yu-Chin Su, Daria Mochly-Rosen. J Cell Sci 2013
13
Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release.
Yeun Su Choo, Gail V W Johnson, Marcy MacDonald, Peter J Detloff, Mathieu Lesort. Hum Mol Genet 2004
Yeun Su Choo, Gail V W Johnson, Marcy MacDonald, Peter J Detloff, Mathieu Lesort. Hum Mol Genet 2004
13
Huntington's disease: from molecular pathogenesis to clinical treatment.
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
13
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
Evandro F Fang, Yujun Hou, Konstantinos Palikaras, Bryan A Adriaanse, Jesse S Kerr, Beimeng Yang, Sofie Lautrup, Md Mahdi Hasan-Olive, Domenica Caponio, Xiuli Dan,[...]. Nat Neurosci 2019
Evandro F Fang, Yujun Hou, Konstantinos Palikaras, Bryan A Adriaanse, Jesse S Kerr, Beimeng Yang, Sofie Lautrup, Md Mahdi Hasan-Olive, Domenica Caponio, Xiuli Dan,[...]. Nat Neurosci 2019
13
Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells.
E Smirnova, L Griparic, D L Shurland, A M van der Bliek. Mol Biol Cell 2001
E Smirnova, L Griparic, D L Shurland, A M van der Bliek. Mol Biol Cell 2001
13
MiD49 and MiD51, new components of the mitochondrial fission machinery.
Catherine S Palmer, Laura D Osellame, David Laine, Olga S Koutsopoulos, Ann E Frazier, Michael T Ryan. EMBO Rep 2011
Catherine S Palmer, Laura D Osellame, David Laine, Olga S Koutsopoulos, Ann E Frazier, Michael T Ryan. EMBO Rep 2011
12
Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage.
Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2012
Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2012
12
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases.
Michael T Lin, M Flint Beal. Nature 2006
Michael T Lin, M Flint Beal. Nature 2006
12
Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins.
Xinglong Wang, Bo Su, Sandra L Siedlak, Paula I Moreira, Hisashi Fujioka, Yang Wang, Gemma Casadesus, Xiongwei Zhu. Proc Natl Acad Sci U S A 2008
Xinglong Wang, Bo Su, Sandra L Siedlak, Paula I Moreira, Hisashi Fujioka, Yang Wang, Gemma Casadesus, Xiongwei Zhu. Proc Natl Acad Sci U S A 2008
12
Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease.
Elizabeth J Slow, Jeremy van Raamsdonk, Daniel Rogers, Sarah H Coleman, Rona K Graham, Yu Deng, Rosemary Oh, Nagat Bissada, Sazzad M Hossain, Yu-Zhou Yang,[...]. Hum Mol Genet 2003
Elizabeth J Slow, Jeremy van Raamsdonk, Daniel Rogers, Sarah H Coleman, Rona K Graham, Yu Deng, Rosemary Oh, Nagat Bissada, Sazzad M Hossain, Yu-Zhou Yang,[...]. Hum Mol Genet 2003
12
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
12
Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance.
Sarah Pickles, Pierre Vigié, Richard J Youle. Curr Biol 2018
Sarah Pickles, Pierre Vigié, Richard J Youle. Curr Biol 2018
12
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy.
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
11
Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo.
Phillip M Rappold, Mei Cui, Jonathan C Grima, Rebecca Z Fan, Karen L de Mesy-Bentley, Linan Chen, Xiaoxi Zhuang, William J Bowers, Kim Tieu. Nat Commun 2014
Phillip M Rappold, Mei Cui, Jonathan C Grima, Rebecca Z Fan, Karen L de Mesy-Bentley, Linan Chen, Xiaoxi Zhuang, William J Bowers, Kim Tieu. Nat Commun 2014
11
Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model.
Seung Hyun Baek, So Jung Park, Jae In Jeong, Sung Hyun Kim, Jihoon Han, Jae Won Kyung, Sang-Ha Baik, Yuri Choi, Bo Youn Choi, Jin Su Park,[...]. J Neurosci 2017
Seung Hyun Baek, So Jung Park, Jae In Jeong, Sung Hyun Kim, Jihoon Han, Jae Won Kyung, Sang-Ha Baik, Yuri Choi, Bo Youn Choi, Jin Su Park,[...]. J Neurosci 2017
11
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
11
Mutant huntingtin aggregates impair mitochondrial movement and trafficking in cortical neurons.
Diane T W Chang, Gordon L Rintoul, Sruthi Pandipati, Ian J Reynolds. Neurobiol Dis 2006
Diane T W Chang, Gordon L Rintoul, Sruthi Pandipati, Ian J Reynolds. Neurobiol Dis 2006
11
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.
Laurent R Gauthier, Bénédicte C Charrin, Maria Borrell-Pagès, Jim P Dompierre, Hélène Rangone, Fabrice P Cordelières, Jan De Mey, Marcy E MacDonald, Volkmar Lessmann, Sandrine Humbert,[...]. Cell 2004
Laurent R Gauthier, Bénédicte C Charrin, Maria Borrell-Pagès, Jim P Dompierre, Hélène Rangone, Fabrice P Cordelières, Jan De Mey, Marcy E MacDonald, Volkmar Lessmann, Sandrine Humbert,[...]. Cell 2004
11
PGC-1α, mitochondrial dysfunction, and Huntington's disease.
Ashu Johri, Abhishek Chandra, M Flint Beal. Free Radic Biol Med 2013
Ashu Johri, Abhishek Chandra, M Flint Beal. Free Radic Biol Med 2013
11
Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration.
Patrick Weydt, Victor V Pineda, Anne E Torrence, Randell T Libby, Terrence F Satterfield, Eduardo R Lazarowski, Merle L Gilbert, Gregory J Morton, Theodor K Bammler, Andrew D Strand,[...]. Cell Metab 2006
Patrick Weydt, Victor V Pineda, Anne E Torrence, Randell T Libby, Terrence F Satterfield, Eduardo R Lazarowski, Merle L Gilbert, Gregory J Morton, Theodor K Bammler, Andrew D Strand,[...]. Cell Metab 2006
11
ER tubules mark sites of mitochondrial division.
Jonathan R Friedman, Laura L Lackner, Matthew West, Jared R DiBenedetto, Jodi Nunnari, Gia K Voeltz. Science 2011
Jonathan R Friedman, Laura L Lackner, Matthew West, Jared R DiBenedetto, Jodi Nunnari, Gia K Voeltz. Science 2011
11
Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission.
Oliver C Losón, Zhiyin Song, Hsiuchen Chen, David C Chan. Mol Biol Cell 2013
Oliver C Losón, Zhiyin Song, Hsiuchen Chen, David C Chan. Mol Biol Cell 2013
10
S-nitrosylation of dynamin-related protein 1 mediates mutant huntingtin-induced mitochondrial fragmentation and neuronal injury in Huntington's disease.
Florian Haun, Tomohiro Nakamura, Alicia D Shiu, Dong-Hyung Cho, Taiji Tsunemi, Emily A Holland, Albert R La Spada, Stuart A Lipton. Antioxid Redox Signal 2013
Florian Haun, Tomohiro Nakamura, Alicia D Shiu, Dong-Hyung Cho, Taiji Tsunemi, Emily A Holland, Albert R La Spada, Stuart A Lipton. Antioxid Redox Signal 2013
13
Huntington disease.
Gillian P Bates, Ray Dorsey, James F Gusella, Michael R Hayden, Chris Kay, Blair R Leavitt, Martha Nance, Christopher A Ross, Rachael I Scahill, Ronald Wetzel,[...]. Nat Rev Dis Primers 2015
Gillian P Bates, Ray Dorsey, James F Gusella, Michael R Hayden, Chris Kay, Blair R Leavitt, Martha Nance, Christopher A Ross, Rachael I Scahill, Ronald Wetzel,[...]. Nat Rev Dis Primers 2015
10
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.
Derek P Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A Gautier, Jie Shen, Mark R Cookson, Richard J Youle. PLoS Biol 2010
Derek P Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A Gautier, Jie Shen, Mark R Cookson, Richard J Youle. PLoS Biol 2010
10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.