Bruno Bernardes de Jesus, Kerstin Schneeberger, Elsa Vera, Agueda Tejera, Calvin B Harley, Maria A Blasco. Aging Cell 2011
Times Cited: 157
Times Cited: 157
Times Cited
Times Co-cited
Similarity
Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer.
Bruno Bernardes de Jesus, Elsa Vera, Kerstin Schneeberger, Agueda M Tejera, Eduard Ayuso, Fatima Bosch, Maria A Blasco. EMBO Mol Med 2012
Bruno Bernardes de Jesus, Elsa Vera, Kerstin Schneeberger, Agueda M Tejera, Eduard Ayuso, Fatima Bosch, Maria A Blasco. EMBO Mol Med 2012
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A natural product telomerase activator as part of a health maintenance program.
Calvin B Harley, Weimin Liu, Maria Blasco, Elsa Vera, William H Andrews, Laura A Briggs, Joseph M Raffaele. Rejuvenation Res 2011
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The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
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Telomeres shorten during ageing of human fibroblasts.
C B Harley, A B Futcher, C W Greider. Nature 1990
C B Harley, A B Futcher, C W Greider. Nature 1990
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Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice.
Mariela Jaskelioff, Florian L Muller, Ji-Hye Paik, Emily Thomas, Shan Jiang, Andrew C Adams, Ergun Sahin, Maria Kost-Alimova, Alexei Protopopov, Juan Cadiñanos,[...]. Nature 2011
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Telomerase-based pharmacologic enhancement of antiviral function of human CD8+ T lymphocytes.
Steven Russell Fauce, Beth D Jamieson, Allison C Chin, Ronald T Mitsuyasu, Stan T Parish, Hwee L Ng, Christina M Ramirez Kitchen, Otto O Yang, Calvin B Harley, Rita B Effros. J Immunol 2008
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A Natural Product Telomerase Activator Lengthens Telomeres in Humans: A Randomized, Double Blind, and Placebo Controlled Study.
Laura Salvador, Gunasekaran Singaravelu, Calvin B Harley, Peter Flom, Anitha Suram, Joseph M Raffaele. Rejuvenation Res 2016
Laura Salvador, Gunasekaran Singaravelu, Calvin B Harley, Peter Flom, Anitha Suram, Joseph M Raffaele. Rejuvenation Res 2016
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Extension of life-span by introduction of telomerase into normal human cells.
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
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Telomere shortening and tumor formation by mouse cells lacking telomerase RNA.
M A Blasco, H W Lee, M P Hande, E Samper, P M Lansdorp, R A DePinho, C W Greider. Cell 1997
M A Blasco, H W Lee, M P Hande, E Samper, P M Lansdorp, R A DePinho, C W Greider. Cell 1997
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Telomerase reverse transcriptase delays aging in cancer-resistant mice.
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Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress.
Shaheda Ahmed, João F Passos, Matthew J Birket, Tina Beckmann, Sebastian Brings, Heiko Peters, Mark A Birch-Machin, Thomas von Zglinicki, Gabriele Saretzki. J Cell Sci 2008
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15
A natural product telomerase activator as part of a health maintenance program: metabolic and cardiovascular response.
Calvin B Harley, Weimin Liu, Peter L Flom, Joseph M Raffaele. Rejuvenation Res 2013
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Shelterin: the protein complex that shapes and safeguards human telomeres.
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Association between telomere length in blood and mortality in people aged 60 years or older.
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Novel telomerase-increasing compound in mouse brain delays the onset of amyotrophic lateral sclerosis.
Erez Eitan, Ailon Tichon, Aviv Gazit, Daniel Gitler, Shimon Slavin, Esther Priel. EMBO Mol Med 2012
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The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability.
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The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
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Accelerated telomere shortening in response to life stress.
Elissa S Epel, Elizabeth H Blackburn, Jue Lin, Firdaus S Dhabhar, Nancy E Adler, Jason D Morrow, Richard M Cawthon. Proc Natl Acad Sci U S A 2004
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12
Telomere dysfunction induces metabolic and mitochondrial compromise.
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Therapeutic effect of androgen therapy in a mouse model of aplastic anemia produced by short telomeres.
Christian Bär, Nicolas Huber, Fabian Beier, Maria A Blasco. Haematologica 2015
Christian Bär, Nicolas Huber, Fabian Beier, Maria A Blasco. Haematologica 2015
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Specific association of human telomerase activity with immortal cells and cancer.
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12
Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage.
Judith Haendeler, Stefan Dröse, Nicole Büchner, Sascha Jakob, Joachim Altschmied, Christine Goy, Ioakim Spyridopoulos, Andreas M Zeiher, Ulrich Brandt, Stefanie Dimmeler. Arterioscler Thromb Vasc Biol 2009
Judith Haendeler, Stefan Dröse, Nicole Büchner, Sascha Jakob, Joachim Altschmied, Christine Goy, Ioakim Spyridopoulos, Andreas M Zeiher, Ulrich Brandt, Stefanie Dimmeler. Arterioscler Thromb Vasc Biol 2009
12
Telomere length in early life predicts lifespan.
Britt J Heidinger, Jonathan D Blount, Winnie Boner, Kate Griffiths, Neil B Metcalfe, Pat Monaghan. Proc Natl Acad Sci U S A 2012
Britt J Heidinger, Jonathan D Blount, Winnie Boner, Kate Griffiths, Neil B Metcalfe, Pat Monaghan. Proc Natl Acad Sci U S A 2012
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The serial cultivation of human diploid cell strains.
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Mammalian telomeres end in a large duplex loop.
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11
Chronic inflammation induces telomere dysfunction and accelerates ageing in mice.
Diana Jurk, Caroline Wilson, João F Passos, Fiona Oakley, Clara Correia-Melo, Laura Greaves, Gabriele Saretzki, Chris Fox, Conor Lawless, Rhys Anderson,[...]. Nat Commun 2014
Diana Jurk, Caroline Wilson, João F Passos, Fiona Oakley, Clara Correia-Melo, Laura Greaves, Gabriele Saretzki, Chris Fox, Conor Lawless, Rhys Anderson,[...]. Nat Commun 2014
11
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation.
Marzia Fumagalli, Francesca Rossiello, Michela Clerici, Sara Barozzi, Davide Cittaro, Jessica M Kaplunov, Gabriele Bucci, Miryana Dobreva, Valentina Matti, Christian M Beausejour,[...]. Nat Cell Biol 2012
Marzia Fumagalli, Francesca Rossiello, Michela Clerici, Sara Barozzi, Davide Cittaro, Jessica M Kaplunov, Gabriele Bucci, Miryana Dobreva, Valentina Matti, Christian M Beausejour,[...]. Nat Cell Biol 2012
11
Transient delivery of modified mRNA encoding TERT rapidly extends telomeres in human cells.
John Ramunas, Eduard Yakubov, Jennifer J Brady, Stéphane Y Corbel, Colin Holbrook, Moritz Brandt, Jonathan Stein, Juan G Santiago, John P Cooke, Helen M Blau. FASEB J 2015
John Ramunas, Eduard Yakubov, Jennifer J Brady, Stéphane Y Corbel, Colin Holbrook, Moritz Brandt, Jonathan Stein, Juan G Santiago, John P Cooke, Helen M Blau. FASEB J 2015
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Essential role of mouse telomerase in highly proliferative organs.
H W Lee, M A Blasco, G J Gottlieb, J W Horner, C W Greider, R A DePinho. Nature 1998
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Functional assessment of pharmacological telomerase activators in human T cells.
Brenda Molgora, Riley Bateman, Greg Sweeney, Danielle Finger, Taylor Dimler, Rita B Effros, Hector F Valenzuela. Cells 2013
Brenda Molgora, Riley Bateman, Greg Sweeney, Danielle Finger, Taylor Dimler, Rita B Effros, Hector F Valenzuela. Cells 2013
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Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells.
Rodrigo T Calado, William T Yewdell, Keisha L Wilkerson, Joshua A Regal, Sachiko Kajigaya, Constantine A Stratakis, Neal S Young. Blood 2009
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Identification of a specific telomere terminal transferase activity in Tetrahymena extracts.
C W Greider, E H Blackburn. Cell 1985
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11
Evaluation of an oral telomerase activator for early age-related macular degeneration - a pilot study.
Coad Thomas Dow, Calvin B Harley. Clin Ophthalmol 2016
Coad Thomas Dow, Calvin B Harley. Clin Ophthalmol 2016
50
Telomere-driven diseases and telomere-targeting therapies.
Paula Martínez, Maria A Blasco. J Cell Biol 2017
Paula Martínez, Maria A Blasco. J Cell Biol 2017
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The rate of increase of short telomeres predicts longevity in mammals.
Elsa Vera, Bruno Bernardes de Jesus, Miguel Foronda, Juana M Flores, Maria A Blasco. Cell Rep 2012
Elsa Vera, Bruno Bernardes de Jesus, Miguel Foronda, Juana M Flores, Maria A Blasco. Cell Rep 2012
10
Telomere length predicts replicative capacity of human fibroblasts.
R C Allsopp, H Vaziri, C Patterson, S Goldstein, E V Younglai, A B Futcher, C W Greider, C B Harley. Proc Natl Acad Sci U S A 1992
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Obesity, cigarette smoking, and telomere length in women.
A M Valdes, T Andrew, J P Gardner, M Kimura, E Oelsner, L F Cherkas, A Aviv, T D Spector. Lancet 2005
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10
10
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.
Darren J Baker, Tobias Wijshake, Tamar Tchkonia, Nathan K LeBrasseur, Bennett G Childs, Bart van de Sluis, James L Kirkland, Jan M van Deursen. Nature 2011
Darren J Baker, Tobias Wijshake, Tamar Tchkonia, Nathan K LeBrasseur, Bennett G Childs, Bart van de Sluis, James L Kirkland, Jan M van Deursen. Nature 2011
10
Telomerase expression confers cardioprotection in the adult mouse heart after acute myocardial infarction.
Christian Bär, Bruno Bernardes de Jesus, Rosa Serrano, Agueda Tejera, Eduard Ayuso, Veronica Jimenez, Ivan Formentini, Maria Bobadilla, Jacques Mizrahi, Alba de Martino,[...]. Nat Commun 2014
Christian Bär, Bruno Bernardes de Jesus, Rosa Serrano, Agueda Tejera, Eduard Ayuso, Veronica Jimenez, Ivan Formentini, Maria Bobadilla, Jacques Mizrahi, Alba de Martino,[...]. Nat Commun 2014
11
Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence.
Graeme Hewitt, Diana Jurk, Francisco D M Marques, Clara Correia-Melo, Timothy Hardy, Agata Gackowska, Rhys Anderson, Morgan Taschuk, Jelena Mann, João F Passos. Nat Commun 2012
Graeme Hewitt, Diana Jurk, Francisco D M Marques, Clara Correia-Melo, Timothy Hardy, Agata Gackowska, Rhys Anderson, Morgan Taschuk, Jelena Mann, João F Passos. Nat Commun 2012
10
A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon.
A M Olovnikov. J Theor Biol 1973
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10
Experimental increase in telomere length leads to faster feather regeneration.
Sophie Reichert, Pierre Bize, Mathilde Arrivé, Sandrine Zahn, Sylvie Massemin, François Criscuolo. Exp Gerontol 2014
Sophie Reichert, Pierre Bize, Mathilde Arrivé, Sandrine Zahn, Sylvie Massemin, François Criscuolo. Exp Gerontol 2014
58
10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.