A citation-based method for searching scientific literature

Richard Mark White, Jennifer Cech, Sutheera Ratanasirintrawoot, Charles Y Lin, Peter B Rahl, Christopher J Burke, Erin Langdon, Matthew L Tomlinson, Jack Mosher, Charles Kaufman, Frank Chen, Hannah K Long, Martin Kramer, Sumon Datta, Donna Neuberg, Scott Granter, Richard A Young, Sean Morrison, Grant N Wheeler, Leonard I Zon. Nature 2011
Times Cited: 316







List of co-cited articles
974 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation.
Charles K Kaufman, Christian Mosimann, Zi Peng Fan, Song Yang, Andrew J Thomas, Julien Ablain, Justin L Tan, Rachel D Fogley, Ellen van Rooijen, Elliott J Hagedorn,[...]. Science 2016
208
31

Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.
David B Sykes, Youmna S Kfoury, François E Mercier, Mathias J Wawer, Jason M Law, Mark K Haynes, Timothy A Lewis, Amir Schajnovitz, Esha Jain, Dongjun Lee,[...]. Cell 2016
207
26

BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma.
E Elizabeth Patton, Hans R Widlund, Jeffery L Kutok, Kamden R Kopani, James F Amatruda, Ryan D Murphey, Stephane Berghmans, Elizabeth A Mayhall, David Traver, Christopher D M Fletcher,[...]. Curr Biol 2005
444
22

Transparent adult zebrafish as a tool for in vivo transplantation analysis.
Richard Mark White, Anna Sessa, Christopher Burke, Teresa Bowman, Jocelyn LeBlanc, Craig Ceol, Caitlin Bourque, Michael Dovey, Wolfram Goessling, Caroline Erter Burns,[...]. Cell Stem Cell 2008
744
20

The zebrafish reference genome sequence and its relationship to the human genome.
Kerstin Howe, Matthew D Clark, Carlos F Torroja, James Torrance, Camille Berthelot, Matthieu Muffato, John E Collins, Sean Humphray, Karen McLaren, Lucy Matthews,[...]. Nature 2013
19

Dependence on the Pyrimidine Biosynthetic Enzyme DHODH Is a Synthetic Lethal Vulnerability in Mutant KRAS-Driven Cancers.
Malvika Koundinya, Judith Sudhalter, Albane Courjaud, Bruno Lionne, Gaetan Touyer, Luc Bonnet, Isabelle Menguy, Isabelle Schreiber, Christelle Perrault, Stephanie Vougier,[...]. Cell Chem Biol 2018
50
36

PTEN Regulates Glutamine Flux to Pyrimidine Synthesis and Sensitivity to Dihydroorotate Dehydrogenase Inhibition.
Deepti Mathur, Elias Stratikopoulos, Sait Ozturk, Nicole Steinbach, Sarah Pegno, Sarah Schoenfeld, Raymund Yong, Vundavalli V Murty, John M Asara, Lewis C Cantley,[...]. Cancer Discov 2017
59
30

Adaptive Reprogramming of De Novo Pyrimidine Synthesis Is a Metabolic Vulnerability in Triple-Negative Breast Cancer.
Kristin K Brown, Jessica B Spinelli, John M Asara, Alex Toker. Cancer Discov 2017
95
17

The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset.
Craig J Ceol, Yariv Houvras, Judit Jane-Valbuena, Steve Bilodeau, David A Orlando, Valentine Battisti, Lauriane Fritsch, William M Lin, Travis J Hollmann, Fabrizio Ferré,[...]. Nature 2011
358
16

Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis.
Trista E North, Wolfram Goessling, Carl R Walkley, Claudia Lengerke, Kamden R Kopani, Allegra M Lord, Gerhard J Weber, Teresa V Bowman, Il-Ho Jang, Tilo Grosser,[...]. Nature 2007
813
14

Toward Minimal Residual Disease-Directed Therapy in Melanoma.
Florian Rambow, Aljosja Rogiers, Oskar Marin-Bejar, Sara Aibar, Julia Femel, Michael Dewaele, Panagiotis Karras, Daniel Brown, Young Hwan Chang, Maria Debiec-Rychter,[...]. Cell 2018
241
14

The novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies.
Sven Christian, Claudia Merz, Laura Evans, Stefan Gradl, Henrik Seidel, Anders Friberg, Ashley Eheim, Pascale Lejeune, Krzysztof Brzezinka, Katja Zimmermann,[...]. Leukemia 2019
68
20

Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma.
Olga Shakhova, Daniel Zingg, Simon M Schaefer, Lisette Hari, Gianluca Civenni, Jacqueline Blunschi, Stéphanie Claudinot, Michal Okoniewski, Friedrich Beermann, Daniela Mihic-Probst,[...]. Nat Cell Biol 2012
173
13


A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Marcus J G W Ladds, Ingeborg M M van Leeuwen, Catherine J Drummond, Su Chu, Alan R Healy, Gergana Popova, Andrés Pastor Fernández, Tanzina Mollick, Suhas Darekar, Saikiran K Sedimbi,[...]. Nat Commun 2018
40
30

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2.
Michael I Love, Wolfgang Huber, Simon Anders. Genome Biol 2014
11

A Quantitative System for Studying Metastasis Using Transparent Zebrafish.
Silja Heilmann, Kajan Ratnakumar, Erin Langdon, Emily Kansler, Isabella Kim, Nathaniel R Campbell, Elizabeth Perry, Amy McMahon, Charles Kaufman, Ellen van Rooijen,[...]. Cancer Res 2015
68
16

Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells.
Martina Bajzikova, Jaromira Kovarova, Ana R Coelho, Stepana Boukalova, Sehyun Oh, Katerina Rohlenova, David Svec, Sona Hubackova, Berwini Endaya, Kristyna Judasova,[...]. Cell Metab 2019
97
11

Zebrafish MITF-Low Melanoma Subtype Models Reveal Transcriptional Subclusters and MITF-Independent Residual Disease.
Jana Travnickova, Sonia Wojciechowska, Ava Khamseh, Philippe Gautier, Daniel V Brown, Thomas Lefevre, Alessandro Brombin, Ailith Ewing, Amy Capper, Michaela Spitzer,[...]. Cancer Res 2019
17
64

Regulation of mammalian nucleotide metabolism and biosynthesis.
Andrew N Lane, Teresa W-M Fan. Nucleic Acids Res 2015
358
10

Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1.
Issam Ben-Sahra, Jessica J Howell, John M Asara, Brendan D Manning. Science 2013
439
10


STAR: ultrafast universal RNA-seq aligner.
Alexander Dobin, Carrie A Davis, Felix Schlesinger, Jorg Drenkow, Chris Zaleski, Sonali Jha, Philippe Batut, Mark Chaisson, Thomas R Gingeras. Bioinformatics 2013
10

Stages of embryonic development of the zebrafish.
C B Kimmel, W W Ballard, S R Kimmel, B Ullmann, T F Schilling. Dev Dyn 1995
10

Zebrafish as tools for drug discovery.
Calum A MacRae, Randall T Peterson. Nat Rev Drug Discov 2015
543
10

RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells.
Cristina Santoriello, Audrey Sporrij, Song Yang, Ryan A Flynn, Telmo Henriques, Bilguujin Dorjsuren, Eugenia Custo Greig, Wyatt McCall, Meredith E Stanhope, Maurizio Fazio,[...]. Nat Cell Biol 2020
20
50

Dihydroorotate dehydrogenase inhibitor A771726 (leflunomide) induces apoptosis and diminishes proliferation of multiple myeloma cells.
Philipp Baumann, Sonja Mandl-Weber, Andreas Völkl, Christian Adam, Irmgard Bumeder, Fuat Oduncu, Ralf Schmidmaier. Mol Cancer Ther 2009
89
10

Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.
Justin L Tan, Rachel D Fogley, Ryan A Flynn, Julien Ablain, Song Yang, Violaine Saint-André, Zi Peng Fan, Brian T Do, Alvaro C Laga, Koh Fujinaga,[...]. Mol Cell 2016
47
19

Quantitative phosphoproteomics reveal mTORC1 activates de novo pyrimidine synthesis.
Aaron M Robitaille, Stefan Christen, Mitsugu Shimobayashi, Marion Cornu, Luca L Fava, Suzette Moes, Cristina Prescianotto-Baschong, Uwe Sauer, Paul Jenoe, Michael N Hall. Science 2013
323
9


Myc-induced T cell leukemia in transgenic zebrafish.
David M Langenau, David Traver, Adolfo A Ferrando, Jeffery L Kutok, Jon C Aster, John P Kanki, Shuo Lin, Ed Prochownik, Nikolaus S Trede, Leonard I Zon,[...]. Science 2003
382
9

Microenvironment-derived factors driving metastatic plasticity in melanoma.
Isabella S Kim, Silja Heilmann, Emily R Kansler, Yan Zhang, Milena Zimmer, Kajan Ratnakumar, Robert L Bowman, Theresa Simon-Vermot, Myles Fennell, Ralph Garippa,[...]. Nat Commun 2017
87
10

Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells.
Xiuxing Wang, Kailin Yang, Qiulian Wu, Leo J Y Kim, Andrew R Morton, Ryan C Gimple, Briana C Prager, Yu Shi, Wenchao Zhou, Shruti Bhargava,[...]. Sci Transl Med 2019
45
20

Pyrimidine pathways in health and disease.
Monika Löffler, Lynette D Fairbanks, Elke Zameitat, Anthony M Marinaki, H Anne Simmonds. Trends Mol Med 2005
143
9

Visualizing Engrafted Human Cancer and Therapy Responses in Immunodeficient Zebrafish.
Chuan Yan, Dalton C Brunson, Qin Tang, Daniel Do, Nicolae A Iftimia, John C Moore, Madeline N Hayes, Alessandra M Welker, Elaine G Garcia, Taronish D Dubash,[...]. Cell 2019
103
9

The melanocyte lineage in development and disease.
Richard L Mort, Ian J Jackson, E Elizabeth Patton. Development 2015
149
9

On dihydroorotate dehydrogenases and their inhibitors and uses.
Hélène Munier-Lehmann, Pierre-Olivier Vidalain, Frédéric Tangy, Yves L Janin. J Med Chem 2013
119
8

Dihydro-orotate dehydrogenase is physically associated with the respiratory complex and its loss leads to mitochondrial dysfunction.
JingXian Fang, Takeshi Uchiumi, Mikako Yagi, Shinya Matsumoto, Rie Amamoto, Shinya Takazaki, Haruyoshi Yamaza, Kazuaki Nonaka, Dongchon Kang. Biosci Rep 2013
61
13

Hooked! Modeling human disease in zebrafish.
Cristina Santoriello, Leonard I Zon. J Clin Invest 2012
268
8

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
8

Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins.
Maomao Zhang, Julie S Di Martino, Robert L Bowman, Nathaniel R Campbell, Sanjeethan C Baksh, Theresa Simon-Vermot, Isabella S Kim, Pearce Haldeman, Chandrani Mondal, Vladimir Yong-Gonzales,[...]. Cancer Discov 2018
132
8

Revisiting the role of dihydroorotate dehydrogenase as a therapeutic target for cancer.
Joseph T Madak, Armand Bankhead, Christine R Cuthbertson, Hollis D Showalter, Nouri Neamati. Pharmacol Ther 2019
59
13

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
8

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq.
Itay Tirosh, Benjamin Izar, Sanjay M Prakadan, Marc H Wadsworth, Daniel Treacy, John J Trombetta, Asaf Rotem, Christopher Rodman, Christine Lian, George Murphy,[...]. Science 2016
8


Identification of DHODH as a therapeutic target in small cell lung cancer.
Leanne Li, Sheng Rong Ng, Caterina I Colón, Benjamin J Drapkin, Peggy P Hsu, Zhaoqi Li, Christopher S Nabel, Caroline A Lewis, Rodrigo Romero, Kim L Mercer,[...]. Sci Transl Med 2019
42
19

Kita driven expression of oncogenic HRAS leads to early onset and highly penetrant melanoma in zebrafish.
Cristina Santoriello, Elisa Gennaro, Viviana Anelli, Martin Distel, Amanda Kelly, Reinhard W Köster, Adam Hurlstone, Marina Mione. PLoS One 2010
96
7

Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia.
Timothy A Lewis, David B Sykes, Jason M Law, Benito Muñoz, Joane K Rustiguel, Maria Cristina Nonato, David T Scadden, Stuart L Schreiber. ACS Med Chem Lett 2016
34
20

Exome sequencing identifies the cause of a mendelian disorder.
Sarah B Ng, Kati J Buckingham, Choli Lee, Abigail W Bigham, Holly K Tabor, Karin M Dent, Chad D Huff, Paul T Shannon, Ethylin Wang Jabs, Deborah A Nickerson,[...]. Nat Genet 2010
7

Pyrimidine biosynthesis links mitochondrial respiration to the p53 pathway.
Anastasia A Khutornenko, Vladimir V Roudko, Boris V Chernyak, Andrey B Vartapetian, Peter M Chumakov, Alexandra G Evstafieva. Proc Natl Acad Sci U S A 2010
109
7


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.