A citation-based method for searching scientific literature

Patricia N Sidharta, Paul L M van Giersbergen, Atef Halabi, Jasper Dingemanse. Eur J Clin Pharmacol 2011
Times Cited: 86







List of co-cited articles
903 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Pharmacology of macitentan, an orally active tissue-targeting dual endothelin receptor antagonist.
Marc Iglarz, Christoph Binkert, Keith Morrison, Walter Fischli, John Gatfield, Alexander Treiber, Thomas Weller, Martin H Bolli, Christoph Boss, Stephan Buchmann,[...]. J Pharmacol Exp Ther 2008
230
69

Macitentan and morbidity and mortality in pulmonary arterial hypertension.
Tomás Pulido, Igor Adzerikho, Richard N Channick, Marion Delcroix, Nazzareno Galiè, Hossein-Ardeschir Ghofrani, Pavel Jansa, Zhi-Cheng Jing, Franck-Olivier Le Brun, Sanjay Mehta,[...]. N Engl J Med 2013
836
56


The discovery of N-[5-(4-bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'-propylsulfamide (Macitentan), an orally active, potent dual endothelin receptor antagonist.
Martin H Bolli, Christoph Boss, Christoph Binkert, Stephan Buchmann, Daniel Bur, Patrick Hess, Marc Iglarz, Solange Meyer, Josiane Rein, Markus Rey,[...]. J Med Chem 2012
92
41

Absorption, distribution, metabolism, and excretion of macitentan, a dual endothelin receptor antagonist, in humans.
Shirin Bruderer, Gérard Hopfgartner, Michael Seiberling, Janine Wank, Patricia N Sidharta, Alexander Treiber, Jasper Dingemanse. Xenobiotica 2012
58
62


Effect of cyclosporine and rifampin on the pharmacokinetics of macitentan, a tissue-targeting dual endothelin receptor antagonist.
Shirin Bruderer, Päivi Aänismaa, Marie-Claude Homery, Stephanie Häusler, Kyle Landskroner, Patricia N Sidharta, Alexander Treiber, Jasper Dingemanse. AAPS J 2012
53
62

Bosentan therapy for pulmonary arterial hypertension.
Lewis J Rubin, David B Badesch, Robyn J Barst, Nazzareno Galie, Carol M Black, Anne Keogh, Tomas Pulido, Adaani Frost, Sebastien Roux, Isabelle Leconte,[...]. N Engl J Med 2002
37

Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study.
R N Channick, G Simonneau, O Sitbon, I M Robbins, A Frost, V F Tapson, D B Badesch, S Roux, M Rainisio, F Bodin,[...]. Lancet 2001
29

Expression of endothelin-1 in the lungs of patients with pulmonary hypertension.
A Giaid, M Yanagisawa, D Langleben, R P Michel, R Levy, H Shennib, S Kimura, T Masaki, W P Duguid, D J Stewart. N Engl J Med 1993
26

The endothelin antagonist bosentan inhibits the canalicular bile salt export pump: a potential mechanism for hepatic adverse reactions.
K Fattinger, C Funk, M Pantze, C Weber, J Reichen, B Stieger, P J Meier. Clin Pharmacol Ther 2001
366
25

Investigation of the effects of ketoconazole on the pharmacokinetics of macitentan, a novel dual endothelin receptor antagonist, in healthy subjects.
Jacob Atsmon, Jasper Dingemanse, Dimitri Shaikevich, Inna Volokhov, Patricia N Sidharta. Clin Pharmacokinet 2013
36
61

Comparison of the dissolution and pharmacokinetic profiles of two galenical formulations of the endothelin receptor antagonist macitentan.
Oliver Kummer, Manuel Haschke, Felix Hammann, Michael Bodmer, Shirin Bruderer, Yann Regnault, Jasper Dingemanse, Stephan Krähenbühl. Eur J Pharm Sci 2009
34
61

Sildenafil citrate therapy for pulmonary arterial hypertension.
Nazzareno Galiè, Hossein A Ghofrani, Adam Torbicki, Robyn J Barst, Lewis J Rubin, David Badesch, Thomas Fleming, Tamiza Parpia, Gary Burgess, Angelo Branzi,[...]. N Engl J Med 2005
24

Ambrisentan for the treatment of pulmonary arterial hypertension: results of the ambrisentan in pulmonary arterial hypertension, randomized, double-blind, placebo-controlled, multicenter, efficacy (ARIES) study 1 and 2.
Nazzareno Galiè, Horst Olschewski, Ronald J Oudiz, Fernando Torres, Adaani Frost, Hossein A Ghofrani, David B Badesch, Michael D McGoon, Vallerie V McLaughlin, Ellen B Roecker,[...]. Circulation 2008
695
24

A novel potent vasoconstrictor peptide produced by vascular endothelial cells.
M Yanagisawa, H Kurihara, S Kimura, Y Tomobe, M Kobayashi, Y Mitsui, Y Yazaki, K Goto, T Masaki. Nature 1988
23

Pharmacokinetics of macitentan in caucasian and Japanese subjects: the influence of ethnicity and sex.
Shirin Bruderer, Joanne Marjason, Patricia N Sidharta, Jasper Dingemanse. Pharmacology 2013
33
60

Interaction profile of macitentan, a new non-selective endothelin-1 receptor antagonist, in vitro.
Johanna Weiss, Dirk Theile, Maximilian Alexander Rüppell, Tobias Speck, Adriana Spalwisz, Walter Emil Haefeli. Eur J Pharmacol 2013
38
47

Efficacy, safety and clinical pharmacology of macitentan in comparison to other endothelin receptor antagonists in the treatment of pulmonary arterial hypertension.
Jasper Dingemanse, Patricia N Sidharta, Willis C Maddrey, Lewis J Rubin, Hani Mickail. Expert Opin Drug Saf 2014
49
36

Tadalafil therapy for pulmonary arterial hypertension.
Nazzareno Galiè, Bruce H Brundage, Hossein A Ghofrani, Ronald J Oudiz, Gerald Simonneau, Zeenat Safdar, Shelley Shapiro, R James White, Melanie Chan, Anthony Beardsworth,[...]. Circulation 2009
716
19

Treatment of pulmonary arterial hypertension.
Marc Humbert, Olivier Sitbon, Gérald Simonneau. N Engl J Med 2004
19

Macitentan for the treatment of idiopathic pulmonary fibrosis: the randomised controlled MUSIC trial.
Ganesh Raghu, Rachel Million-Rousseau, Adele Morganti, Loyc Perchenet, Juergen Behr. Eur Respir J 2013
168
19

Ambrisentan therapy for pulmonary arterial hypertension.
Nazzareno Galié, David Badesch, Ronald Oudiz, Gérald Simonneau, Michael D McGoon, Anne M Keogh, Adaani E Frost, Diane Zwicke, Robert Naeije, Shelley Shapiro,[...]. J Am Coll Cardiol 2005
325
18

Survival in patients with primary pulmonary hypertension. Results from a national prospective registry.
G E D'Alonzo, R J Barst, S M Ayres, E H Bergofsky, B H Brundage, K M Detre, A P Fishman, R M Goldring, B M Groves, J T Kernis. Ann Intern Med 1991
18

Pharmacokinetics of the novel dual endothelin receptor antagonist macitentan in subjects with hepatic or renal impairment.
Patricia N Sidharta, Nicolas Lindegger, Ivan Ulč, Jasper Dingemanse. J Clin Pharmacol 2014
26
61

A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension.
R J Barst, L J Rubin, W A Long, M D McGoon, S Rich, D B Badesch, B M Groves, V F Tapson, R C Bourge, B H Brundage,[...]. N Engl J Med 1996
17


Inhaled iloprost for severe pulmonary hypertension.
Horst Olschewski, Gerald Simonneau, Nazzareno Galiè, Timothy Higenbottam, Robert Naeije, Lewis J Rubin, Sylvia Nikkho, Rudolf Speich, Marius M Hoeper, Jürgen Behr,[...]. N Engl J Med 2002
16

Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension: a double-blind, randomized, placebo-controlled trial.
Gerald Simonneau, Robyn J Barst, Nazzareno Galie, Robert Naeije, Stuart Rich, Robert C Bourge, Anne Keogh, Ronald Oudiz, Adaani Frost, Shelmer D Blackburn,[...]. Am J Respir Crit Care Med 2002
973
15

Increased plasma endothelin-1 in pulmonary hypertension: marker or mediator of disease?
D J Stewart, R D Levy, P Cernacek, D Langleben. Ann Intern Med 1991
836
15

Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): a double-blind, randomised controlled trial.
N Galiè, Lj Rubin, Mm Hoeper, P Jansa, H Al-Hiti, Gmb Meyer, E Chiossi, A Kusic-Pajic, G Simonneau. Lancet 2008
642
15

Macitentan does not interfere with hepatic bile salt transport.
Alexander Treiber, Päivi Äänismaa, Ruben de Kanter, Stephane Delahaye, Marianne Treher, Patrick Hess, Patricia Sidharta. J Pharmacol Exp Ther 2014
31
41


Long-term ambrisentan therapy for the treatment of pulmonary arterial hypertension.
Ronald J Oudiz, Nazzareno Galiè, Horst Olschewski, Fernando Torres, Adaani Frost, Hossein A Ghofrani, David B Badesch, Michael D McGoon, Vallerie V McLaughlin, Ellen B Roecker,[...]. J Am Coll Cardiol 2009
166
13

An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension.
B W Christman, C D McPherson, J H Newman, G A King, G R Bernard, B M Groves, J E Loyd. N Engl J Med 1992
893
13

Results of European post-marketing surveillance of bosentan in pulmonary hypertension.
M Humbert, E S Segal, D G Kiely, J Carlsen, B Schwierin, M M Hoeper. Eur Respir J 2007
202
13

Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study.
Nazzareno Galiè, Maurice Beghetti, Michael A Gatzoulis, John Granton, Rolf M F Berger, Andrea Lauer, Eleonora Chiossi, Michael Landzberg. Circulation 2006
565
12

Combination of bosentan with epoprostenol in pulmonary arterial hypertension: BREATHE-2.
M Humbert, R J Barst, I M Robbins, R N Channick, N Galiè, A Boonstra, L J Rubin, E M Horn, A Manes, G Simonneau. Eur Respir J 2004
437
12

Sitaxsentan therapy for pulmonary arterial hypertension.
Robyn J Barst, David Langleben, Adaani Frost, Evelyn M Horn, Ronald Oudiz, Shelley Shapiro, Vallerie McLaughlin, Nicholas Hill, Victor F Tapson, Ivan M Robbins,[...]. Am J Respir Crit Care Med 2004
503
12

Guidelines for the diagnosis and treatment of pulmonary hypertension.
N Galiè, M M Hoeper, M Humbert, A Torbicki, J-L Vachiery, J A Barbera, M Beghetti, P Corris, S Gaine, J S Gibbs,[...]. Eur Respir J 2009
894
12


Updated evidence-based treatment algorithm in pulmonary arterial hypertension.
Robyn J Barst, J Simon R Gibbs, Hossein A Ghofrani, Marius M Hoeper, Vallerie V McLaughlin, Lewis J Rubin, Olivier Sitbon, Victor F Tapson, Nazzareno Galiè. J Am Coll Cardiol 2009
372
11

Updated clinical classification of pulmonary hypertension.
Gérald Simonneau, Ivan M Robbins, Maurice Beghetti, Richard N Channick, Marion Delcroix, Christopher P Denton, C Gregory Elliott, Sean P Gaine, Mark T Gladwin, Zhi-Cheng Jing,[...]. J Am Coll Cardiol 2009
11

Riociguat for chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension: a phase II study.
H A Ghofrani, M M Hoeper, M Halank, F J Meyer, G Staehler, J Behr, R Ewert, G Weimann, F Grimminger. Eur Respir J 2010
169
11

First acute haemodynamic study of soluble guanylate cyclase stimulator riociguat in pulmonary hypertension.
F Grimminger, G Weimann, R Frey, R Voswinckel, M Thamm, D Bölkow, N Weissmann, W Mück, S Unger, G Wensing,[...]. Eur Respir J 2009
171
11

Liver toxicity of sitaxentan in pulmonary arterial hypertension.
N Galiè, M M Hoeper, J S R Gibbs, G Simonneau. Eur Respir J 2011
37
27

Mutual pharmacokinetic interactions between steady-state bosentan and sildenafil.
Gary Burgess, Hans Hoogkamer, Lorraine Collings, Jasper Dingemanse. Eur J Clin Pharmacol 2008
119
11

Addition of inhaled treprostinil to oral therapy for pulmonary arterial hypertension: a randomized controlled clinical trial.
Vallerie V McLaughlin, Raymond L Benza, Lewis J Rubin, Richard N Channick, Robert Voswinckel, Victor F Tapson, Ivan M Robbins, Horst Olschewski, Melvyn Rubenfire, Werner Seeger. J Am Coll Cardiol 2010
373
11

Selexipag: an oral, selective prostacyclin receptor agonist for the treatment of pulmonary arterial hypertension.
Gérald Simonneau, Adam Torbicki, Marius M Hoeper, Marion Delcroix, Kristóf Karlócai, Nazzareno Galiè, Bruno Degano, Diana Bonderman, Marcin Kurzyna, Michela Efficace,[...]. Eur Respir J 2012
211
11

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.
A Inoue, M Yanagisawa, S Kimura, Y Kasuya, T Miyauchi, K Goto, T Masaki. Proc Natl Acad Sci U S A 1989
11


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.