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Times Cited: 1148
Times Cited: 1148
Times Cited
Times Co-cited
Similarity
A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter.
Diego De Stefani, Anna Raffaello, Enrico Teardo, Ildikò Szabò, Rosario Rizzuto. Nature 2011
Diego De Stefani, Anna Raffaello, Enrico Teardo, Ildikò Szabò, Rosario Rizzuto. Nature 2011
34
Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter.
Joshua M Baughman, Fabiana Perocchi, Hany S Girgis, Molly Plovanich, Casey A Belcher-Timme, Yasemin Sancak, X Robert Bao, Laura Strittmatter, Olga Goldberger, Roman L Bogorad,[...]. Nature 2011
Joshua M Baughman, Fabiana Perocchi, Hany S Girgis, Molly Plovanich, Casey A Belcher-Timme, Yasemin Sancak, X Robert Bao, Laura Strittmatter, Olga Goldberger, Roman L Bogorad,[...]. Nature 2011
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NCLX is an essential component of mitochondrial Na+/Ca2+ exchange.
Raz Palty, William F Silverman, Michal Hershfinkel, Teresa Caporale, Stefano L Sensi, Julia Parnis, Christiane Nolte, Daniel Fishman, Varda Shoshan-Barmatz, Sharon Herrmann,[...]. Proc Natl Acad Sci U S A 2010
Raz Palty, William F Silverman, Michal Hershfinkel, Teresa Caporale, Stefano L Sensi, Julia Parnis, Christiane Nolte, Daniel Fishman, Varda Shoshan-Barmatz, Sharon Herrmann,[...]. Proc Natl Acad Sci U S A 2010
24
The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter.
Xin Pan, Jie Liu, Tiffany Nguyen, Chengyu Liu, Junhui Sun, Yanjie Teng, Maria M Fergusson, Ilsa I Rovira, Michele Allen, Danielle A Springer,[...]. Nat Cell Biol 2013
Xin Pan, Jie Liu, Tiffany Nguyen, Chengyu Liu, Junhui Sun, Yanjie Teng, Maria M Fergusson, Ilsa I Rovira, Michele Allen, Danielle A Springer,[...]. Nat Cell Biol 2013
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Mitochondria as sensors and regulators of calcium signalling.
Rosario Rizzuto, Diego De Stefani, Anna Raffaello, Cristina Mammucari. Nat Rev Mol Cell Biol 2012
Rosario Rizzuto, Diego De Stefani, Anna Raffaello, Cristina Mammucari. Nat Rev Mol Cell Biol 2012
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EMRE is an essential component of the mitochondrial calcium uniporter complex.
Yasemin Sancak, Andrew L Markhard, Toshimori Kitami, Erika Kovács-Bogdán, Kimberli J Kamer, Namrata D Udeshi, Steven A Carr, Dipayan Chaudhuri, David E Clapham, Andrew A Li,[...]. Science 2013
Yasemin Sancak, Andrew L Markhard, Toshimori Kitami, Erika Kovács-Bogdán, Kimberli J Kamer, Namrata D Udeshi, Steven A Carr, Dipayan Chaudhuri, David E Clapham, Andrew A Li,[...]. Science 2013
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The mitochondrial calcium uniporter is a highly selective ion channel.
Yuriy Kirichok, Grigory Krapivinsky, David E Clapham. Nature 2004
Yuriy Kirichok, Grigory Krapivinsky, David E Clapham. Nature 2004
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Regulation of mitochondrial dehydrogenases by calcium ions.
Richard M Denton. Biochim Biophys Acta 2009
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MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake.
Fabiana Perocchi, Vishal M Gohil, Hany S Girgis, X Robert Bao, Janet E McCombs, Amy E Palmer, Vamsi K Mootha. Nature 2010
Fabiana Perocchi, Vishal M Gohil, Hany S Girgis, X Robert Bao, Janet E McCombs, Amy E Palmer, Vamsi K Mootha. Nature 2010
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MICU1 controls both the threshold and cooperative activation of the mitochondrial Ca²⁺ uniporter.
György Csordás, Tünde Golenár, Erin L Seifert, Kimberli J Kamer, Yasemin Sancak, Fabiana Perocchi, Cynthia Moffat, David Weaver, Sergio de la Fuente Perez, Roman Bogorad,[...]. Cell Metab 2013
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The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit.
Anna Raffaello, Diego De Stefani, Davide Sabbadin, Enrico Teardo, Giulia Merli, Anne Picard, Vanessa Checchetto, Stefano Moro, Ildikò Szabò, Rosario Rizzuto. EMBO J 2013
Anna Raffaello, Diego De Stefani, Davide Sabbadin, Enrico Teardo, Giulia Merli, Anne Picard, Vanessa Checchetto, Stefano Moro, Ildikò Szabò, Rosario Rizzuto. EMBO J 2013
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MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism.
Karthik Mallilankaraman, César Cárdenas, Patrick J Doonan, Harish C Chandramoorthy, Krishna M Irrinki, Tünde Golenár, György Csordás, Priyanka Madireddi, Jun Yang, Marioly Müller,[...]. Nat Cell Biol 2012
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The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition.
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14
Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels.
György Szabadkai, Katiuscia Bianchi, Péter Várnai, Diego De Stefani, Mariusz R Wieckowski, Dario Cavagna, Anikó I Nagy, Tamás Balla, Rosario Rizzuto. J Cell Biol 2006
György Szabadkai, Katiuscia Bianchi, Péter Várnai, Diego De Stefani, Mariusz R Wieckowski, Dario Cavagna, Anikó I Nagy, Tamás Balla, Rosario Rizzuto. J Cell Biol 2006
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Regulation of mitochondrial ATP synthesis by calcium: evidence for a long-term metabolic priming.
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Calcium uptake by rat kidney mitochondria.
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The Mitochondrial Calcium Uniporter Selectively Matches Metabolic Output to Acute Contractile Stress in the Heart.
Jennifer Q Kwong, Xiyuan Lu, Robert N Correll, Jennifer A Schwanekamp, Ronald J Vagnozzi, Michelle A Sargent, Allen J York, Jianyi Zhang, Donald M Bers, Jeffery D Molkentin. Cell Rep 2015
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13
MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival.
Karthik Mallilankaraman, Patrick Doonan, César Cárdenas, Harish C Chandramoorthy, Marioly Müller, Russell Miller, Nicholas E Hoffman, Rajesh Kumar Gandhirajan, Jordi Molgó, Morris J Birnbaum,[...]. Cell 2012
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13
MICU1 and MICU2 finely tune the mitochondrial Ca2+ uniporter by exerting opposite effects on MCU activity.
Maria Patron, Vanessa Checchetto, Anna Raffaello, Enrico Teardo, Denis Vecellio Reane, Maura Mantoan, Veronica Granatiero, Ildikò Szabò, Diego De Stefani, Rosario Rizzuto. Mol Cell 2014
Maria Patron, Vanessa Checchetto, Anna Raffaello, Enrico Teardo, Denis Vecellio Reane, Maura Mantoan, Veronica Granatiero, Ildikò Szabò, Diego De Stefani, Rosario Rizzuto. Mol Cell 2014
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MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling.
Molly Plovanich, Roman L Bogorad, Yasemin Sancak, Kimberli J Kamer, Laura Strittmatter, Andrew A Li, Hany S Girgis, Satya Kuchimanchi, Jack De Groot, Lauren Speciner,[...]. PLoS One 2013
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Enjoy the Trip: Calcium in Mitochondria Back and Forth.
Diego De Stefani, Rosario Rizzuto, Tullio Pozzan. Annu Rev Biochem 2016
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The mitochondrial uniporter controls fight or flight heart rate increases.
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12
The effects of calcium ions and adenine nucleotides on the activity of pig heart 2-oxoglutarate dehydrogenase complex.
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The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability.
Timothy S Luongo, Jonathan P Lambert, Polina Gross, Mary Nwokedi, Alyssa A Lombardi, Santhanam Shanmughapriya, April C Carpenter, Devin Kolmetzky, Erhe Gao, Jop H van Berlo,[...]. Nature 2017
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The machineries, regulation and cellular functions of mitochondrial calcium.
Carlotta Giorgi, Saverio Marchi, Paolo Pinton. Nat Rev Mol Cell Biol 2018
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Mitochondrial transport of cations: channels, exchangers, and permeability transition.
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MICU1 and MICU2 play nonredundant roles in the regulation of the mitochondrial calcium uniporter.
Kimberli J Kamer, Vamsi K Mootha. EMBO Rep 2014
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Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses.
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10
Recombinant expression of the voltage-dependent anion channel enhances the transfer of Ca2+ microdomains to mitochondria.
Elena Rapizzi, Paolo Pinton, Gyorgy Szabadkai, Mariusz R Wieckowski, Gregoire Vandecasteele, Geoff Baird, Richard A Tuft, Kevin E Fogarty, Rosario Rizzuto. J Cell Biol 2002
Elena Rapizzi, Paolo Pinton, Gyorgy Szabadkai, Mariusz R Wieckowski, Gregoire Vandecasteele, Geoff Baird, Richard A Tuft, Kevin E Fogarty, Rosario Rizzuto. J Cell Biol 2002
10
Assessment of cardiac function in mice lacking the mitochondrial calcium uniporter.
Kira M Holmström, Xin Pan, Julia C Liu, Sara Menazza, Jie Liu, Tiffany T Nguyen, Haihui Pan, Randi J Parks, Stasia Anderson, Audrey Noguchi,[...]. J Mol Cell Cardiol 2015
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11
Genome-wide RNAi screen identifies Letm1 as a mitochondrial Ca2+/H+ antiporter.
Dawei Jiang, Linlin Zhao, David E Clapham. Science 2009
Dawei Jiang, Linlin Zhao, David E Clapham. Science 2009
10
Mitochondrial calcium overload is a key determinant in heart failure.
Gaetano Santulli, Wenjun Xie, Steven R Reiken, Andrew R Marks. Proc Natl Acad Sci U S A 2015
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Ca(2+) activation of heart mitochondrial oxidative phosphorylation: role of the F(0)/F(1)-ATPase.
P R Territo, V K Mootha, S A French, R S Balaban. Am J Physiol Cell Physiol 2000
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9
Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling.
Clare V Logan, György Szabadkai, Jenny A Sharpe, David A Parry, Silvia Torelli, Anne-Marie Childs, Marjolein Kriek, Rahul Phadke, Colin A Johnson, Nicola Y Roberts,[...]. Nat Genet 2014
Clare V Logan, György Szabadkai, Jenny A Sharpe, David A Parry, Silvia Torelli, Anne-Marie Childs, Marjolein Kriek, Rahul Phadke, Colin A Johnson, Nicola Y Roberts,[...]. Nat Genet 2014
9
EMRE Is a Matrix Ca(2+) Sensor that Governs Gatekeeping of the Mitochondrial Ca(2+) Uniporter.
Horia Vais, Karthik Mallilankaraman, Don-On Daniel Mak, Henry Hoff, Riley Payne, Jessica E Tanis, J Kevin Foskett. Cell Rep 2016
Horia Vais, Karthik Mallilankaraman, Don-On Daniel Mak, Henry Hoff, Riley Payne, Jessica E Tanis, J Kevin Foskett. Cell Rep 2016
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Mitofusin 2 tethers endoplasmic reticulum to mitochondria.
Olga Martins de Brito, Luca Scorrano. Nature 2008
Olga Martins de Brito, Luca Scorrano. Nature 2008
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Effect of calcium on the oxidative phosphorylation cascade in skeletal muscle mitochondria.
Brian Glancy, Wayne T Willis, David J Chess, Robert S Balaban. Biochemistry 2013
Brian Glancy, Wayne T Willis, David J Chess, Robert S Balaban. Biochemistry 2013
9
Activity of the mitochondrial calcium uniporter varies greatly between tissues.
Francesca Fieni, Sung Bae Lee, Yuh Nung Jan, Yuriy Kirichok. Nat Commun 2012
Francesca Fieni, Sung Bae Lee, Yuh Nung Jan, Yuriy Kirichok. Nat Commun 2012
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Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria.
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8
MICU3 is a tissue-specific enhancer of mitochondrial calcium uptake.
Maria Patron, Veronica Granatiero, Javier Espino, Rosario Rizzuto, Diego De Stefani. Cell Death Differ 2019
Maria Patron, Veronica Granatiero, Javier Espino, Rosario Rizzuto, Diego De Stefani. Cell Death Differ 2019
9
Elevated cytosolic Na+ decreases mitochondrial Ca2+ uptake during excitation-contraction coupling and impairs energetic adaptation in cardiac myocytes.
Christoph Maack, Sonia Cortassa, Miguel A Aon, Anand N Ganesan, Ting Liu, Brian O'Rourke. Circ Res 2006
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Structural and functional features and significance of the physical linkage between ER and mitochondria.
György Csordás, Christian Renken, Péter Várnai, Ludivine Walter, David Weaver, Karolyn F Buttle, Tamás Balla, Carmen A Mannella, György Hajnóczky. J Cell Biol 2006
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The release of calcium from heart mitochondria by sodium.
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Mitochondrial fission, fusion, and stress.
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Stimulation by calcium ions of pyruvate dehydrogenase phosphate phosphatase.
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Cytosolic, but not matrix, calcium is essential for adjustment of mitochondrial pyruvate supply.
Marten Szibor, Zemfira Gizatullina, Timur Gainutdinov, Thomas Endres, Grazyna Debska-Vielhaber, Matthias Kunz, Niki Karavasili, Kerstin Hallmann, Frank Schreiber, Alexandra Bamberger,[...]. J Biol Chem 2020
Marten Szibor, Zemfira Gizatullina, Timur Gainutdinov, Thomas Endres, Grazyna Debska-Vielhaber, Matthias Kunz, Niki Karavasili, Kerstin Hallmann, Frank Schreiber, Alexandra Bamberger,[...]. J Biol Chem 2020
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Tissue-Specific Mitochondrial Decoding of Cytoplasmic Ca2+ Signals Is Controlled by the Stoichiometry of MICU1/2 and MCU.
Melanie Paillard, György Csordás, Gergö Szanda, Tünde Golenár, Valentina Debattisti, Adam Bartok, Nadan Wang, Cynthia Moffat, Erin L Seifert, András Spät,[...]. Cell Rep 2017
Melanie Paillard, György Csordás, Gergö Szanda, Tünde Golenár, Valentina Debattisti, Adam Bartok, Nadan Wang, Cynthia Moffat, Erin L Seifert, András Spät,[...]. Cell Rep 2017
7
Cryo-EM structures of fungal and metazoan mitochondrial calcium uniporters.
Rozbeh Baradaran, Chongyuan Wang, Andrew Francis Siliciano, Stephen Barstow Long. Nature 2018
Rozbeh Baradaran, Chongyuan Wang, Andrew Francis Siliciano, Stephen Barstow Long. Nature 2018
8
MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload.
Julia C Liu, Jie Liu, Kira M Holmström, Sara Menazza, Randi J Parks, Maria M Fergusson, Zu-Xi Yu, Danielle A Springer, Charles Halsey, Chengyu Liu,[...]. Cell Rep 2016
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7
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.