Taro Kawai, Shizuo Akira. Immunity 2011
Times Cited: 2236
Times Cited: 2236
Times Cited
Times Co-cited
Similarity
15
Pathogen recognition and inflammatory signaling in innate immune defenses.
Trine H Mogensen. Clin Microbiol Rev 2009
Trine H Mogensen. Clin Microbiol Rev 2009
9
The history of Toll-like receptors - redefining innate immunity.
Luke A J O'Neill, Douglas Golenbock, Andrew G Bowie. Nat Rev Immunol 2013
Luke A J O'Neill, Douglas Golenbock, Andrew G Bowie. Nat Rev Immunol 2013
8
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8.
Florian Heil, Hiroaki Hemmi, Hubertus Hochrein, Franziska Ampenberger, Carsten Kirschning, Shizuo Akira, Grayson Lipford, Hermann Wagner, Stefan Bauer. Science 2004
Florian Heil, Hiroaki Hemmi, Hubertus Hochrein, Franziska Ampenberger, Carsten Kirschning, Shizuo Akira, Grayson Lipford, Hermann Wagner, Stefan Bauer. Science 2004
8
A Toll-like receptor recognizes bacterial DNA.
H Hemmi, O Takeuchi, T Kawai, T Kaisho, S Sato, H Sanjo, M Matsumoto, K Hoshino, H Wagner, K Takeda,[...]. Nature 2000
H Hemmi, O Takeuchi, T Kawai, T Kaisho, S Sato, H Sanjo, M Matsumoto, K Hoshino, H Wagner, K Takeda,[...]. Nature 2000
7
Toll-like receptors: critical proteins linking innate and acquired immunity.
S Akira, K Takeda, T Kaisho. Nat Immunol 2001
S Akira, K Takeda, T Kaisho. Nat Immunol 2001
6
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors.
Taro Kawai, Shizuo Akira. Nat Immunol 2010
Taro Kawai, Shizuo Akira. Nat Immunol 2010
6
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3.
L Alexopoulou, A C Holt, R Medzhitov, R A Flavell. Nature 2001
L Alexopoulou, A C Holt, R Medzhitov, R A Flavell. Nature 2001
6
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.
Lijun Sun, Jiaxi Wu, Fenghe Du, Xiang Chen, Zhijian J Chen. Science 2013
Lijun Sun, Jiaxi Wu, Fenghe Du, Xiang Chen, Zhijian J Chen. Science 2013
6
Toll-like Receptors and the Control of Immunity.
Katherine A Fitzgerald, Jonathan C Kagan. Cell 2020
Katherine A Fitzgerald, Jonathan C Kagan. Cell 2020
6
IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.
Katherine A Fitzgerald, Sarah M McWhirter, Kerrie L Faia, Daniel C Rowe, Eicke Latz, Douglas T Golenbock, Anthony J Coyle, Sha-Mei Liao, Tom Maniatis. Nat Immunol 2003
Katherine A Fitzgerald, Sarah M McWhirter, Kerrie L Faia, Daniel C Rowe, Eicke Latz, Douglas T Golenbock, Anthony J Coyle, Sha-Mei Liao, Tom Maniatis. Nat Immunol 2003
5
STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway.
Yasuo Tanaka, Zhijian J Chen. Sci Signal 2012
Yasuo Tanaka, Zhijian J Chen. Sci Signal 2012
5
5
Innate immune pattern recognition: a cell biological perspective.
Sky W Brubaker, Kevin S Bonham, Ivan Zanoni, Jonathan C Kagan. Annu Rev Immunol 2015
Sky W Brubaker, Kevin S Bonham, Ivan Zanoni, Jonathan C Kagan. Annu Rev Immunol 2015
5
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses.
Mitsutoshi Yoneyama, Mika Kikuchi, Takashi Natsukawa, Noriaki Shinobu, Tadaatsu Imaizumi, Makoto Miyagishi, Kazunari Taira, Shizuo Akira, Takashi Fujita. Nat Immunol 2004
Mitsutoshi Yoneyama, Mika Kikuchi, Takashi Natsukawa, Noriaki Shinobu, Tadaatsu Imaizumi, Makoto Miyagishi, Kazunari Taira, Shizuo Akira, Takashi Fujita. Nat Immunol 2004
5
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.
K J Livak, T D Schmittgen. Methods 2001
K J Livak, T D Schmittgen. Methods 2001
5
Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway.
Hiroaki Hemmi, Tsuneyasu Kaisho, Osamu Takeuchi, Shintaro Sato, Hideki Sanjo, Katsuaki Hoshino, Takao Horiuchi, Hideyuki Tomizawa, Kiyoshi Takeda, Shizuo Akira. Nat Immunol 2002
Hiroaki Hemmi, Tsuneyasu Kaisho, Osamu Takeuchi, Shintaro Sato, Hideki Sanjo, Katsuaki Hoshino, Takao Horiuchi, Hideyuki Tomizawa, Kiyoshi Takeda, Shizuo Akira. Nat Immunol 2002
5
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling.
Luke A J O'Neill, Andrew G Bowie. Nat Rev Immunol 2007
Luke A J O'Neill, Andrew G Bowie. Nat Rev Immunol 2007
4
IFI16 is an innate immune sensor for intracellular DNA.
Leonie Unterholzner, Sinead E Keating, Marcin Baran, Kristy A Horan, Søren B Jensen, Shruti Sharma, Cherilyn M Sirois, Tengchuan Jin, Eicke Latz, T Sam Xiao,[...]. Nat Immunol 2010
Leonie Unterholzner, Sinead E Keating, Marcin Baran, Kristy A Horan, Søren B Jensen, Shruti Sharma, Cherilyn M Sirois, Tengchuan Jin, Eicke Latz, T Sam Xiao,[...]. Nat Immunol 2010
4
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity.
Hiroki Ishikawa, Zhe Ma, Glen N Barber. Nature 2009
Hiroki Ishikawa, Zhe Ma, Glen N Barber. Nature 2009
4
Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects.
Xiao-Dong Li, Jiaxi Wu, Daxing Gao, Hua Wang, Lijun Sun, Zhijian J Chen. Science 2013
Xiao-Dong Li, Jiaxi Wu, Daxing Gao, Hua Wang, Lijun Sun, Zhijian J Chen. Science 2013
4
Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA.
Jiaxi Wu, Lijun Sun, Xiang Chen, Fenghe Du, Heping Shi, Chuo Chen, Zhijian J Chen. Science 2013
Jiaxi Wu, Lijun Sun, Xiang Chen, Fenghe Du, Heping Shi, Chuo Chen, Zhijian J Chen. Science 2013
4
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling.
Hiroki Ishikawa, Glen N Barber. Nature 2008
Hiroki Ishikawa, Glen N Barber. Nature 2008
4
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta.
Jonathan C Kagan, Tian Su, Tiffany Horng, Amy Chow, Shizuo Akira, Ruslan Medzhitov. Nat Immunol 2008
Jonathan C Kagan, Tian Su, Tiffany Horng, Amy Chow, Shizuo Akira, Ruslan Medzhitov. Nat Immunol 2008
4
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.
Chaolin Huang, Yeming Wang, Xingwang Li, Lili Ren, Jianping Zhao, Yi Hu, Li Zhang, Guohui Fan, Jiuyang Xu, Xiaoying Gu,[...]. Lancet 2020
Chaolin Huang, Yeming Wang, Xingwang Li, Lili Ren, Jianping Zhao, Yi Hu, Li Zhang, Guohui Fan, Jiuyang Xu, Xiaoying Gu,[...]. Lancet 2020
4
Pathogen recognition by the innate immune system.
Himanshu Kumar, Taro Kawai, Shizuo Akira. Int Rev Immunol 2011
Himanshu Kumar, Taro Kawai, Shizuo Akira. Int Rev Immunol 2011
4
Toll-like receptor control of the adaptive immune responses.
Akiko Iwasaki, Ruslan Medzhitov. Nat Immunol 2004
Akiko Iwasaki, Ruslan Medzhitov. Nat Immunol 2004
4
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses.
Hiroki Kato, Osamu Takeuchi, Shintaro Sato, Mitsutoshi Yoneyama, Masahiro Yamamoto, Kosuke Matsui, Satoshi Uematsu, Andreas Jung, Taro Kawai, Ken J Ishii,[...]. Nature 2006
Hiroki Kato, Osamu Takeuchi, Shintaro Sato, Mitsutoshi Yoneyama, Masahiro Yamamoto, Kosuke Matsui, Satoshi Uematsu, Andreas Jung, Taro Kawai, Ken J Ishii,[...]. Nature 2006
4
TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk.
J Brown, H Wang, G N Hajishengallis, M Martin. J Dent Res 2011
J Brown, H Wang, G N Hajishengallis, M Martin. J Dent Res 2011
3
RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway.
Yu-Hsin Chiu, John B Macmillan, Zhijian J Chen. Cell 2009
Yu-Hsin Chiu, John B Macmillan, Zhijian J Chen. Cell 2009
3
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC.
Veit Hornung, Andrea Ablasser, Marie Charrel-Dennis, Franz Bauernfeind, Gabor Horvath, Daniel R Caffrey, Eicke Latz, Katherine A Fitzgerald. Nature 2009
Veit Hornung, Andrea Ablasser, Marie Charrel-Dennis, Franz Bauernfeind, Gabor Horvath, Daniel R Caffrey, Eicke Latz, Katherine A Fitzgerald. Nature 2009
3
IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection.
Nagaraj Kerur, Mohanan Valiya Veettil, Neelam Sharma-Walia, Virginie Bottero, Sathish Sadagopan, Pushpalatha Otageri, Bala Chandran. Cell Host Microbe 2011
Nagaraj Kerur, Mohanan Valiya Veettil, Neelam Sharma-Walia, Virginie Bottero, Sathish Sadagopan, Pushpalatha Otageri, Bala Chandran. Cell Host Microbe 2011
3
Toll-like receptors and innate immunity.
Himanshu Kumar, Taro Kawai, Shizuo Akira. Biochem Biophys Res Commun 2009
Himanshu Kumar, Taro Kawai, Shizuo Akira. Biochem Biophys Res Commun 2009
3
3
Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.
Pu Gao, Manuel Ascano, Yang Wu, Winfried Barchet, Barbara L Gaffney, Thomas Zillinger, Artem A Serganov, Yizhou Liu, Roger A Jones, Gunther Hartmann,[...]. Cell 2013
Pu Gao, Manuel Ascano, Yang Wu, Winfried Barchet, Barbara L Gaffney, Thomas Zillinger, Artem A Serganov, Yizhou Liu, Roger A Jones, Gunther Hartmann,[...]. Cell 2013
3
cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders.
Liudmila Andreeva, Björn Hiller, Dirk Kostrewa, Charlotte Lässig, Carina C de Oliveira Mann, David Jan Drexler, Andreas Maiser, Moritz Gaidt, Heinrich Leonhardt, Veit Hornung,[...]. Nature 2017
Liudmila Andreeva, Björn Hiller, Dirk Kostrewa, Charlotte Lässig, Carina C de Oliveira Mann, David Jan Drexler, Andreas Maiser, Moritz Gaidt, Heinrich Leonhardt, Veit Hornung,[...]. Nature 2017
3
The innate immune sensor IFI16 recognizes foreign DNA in the nucleus by scanning along the duplex.
Sarah A Stratmann, Seamus R Morrone, Antoine M van Oijen, Jungsan Sohn. Elife 2015
Sarah A Stratmann, Seamus R Morrone, Antoine M van Oijen, Jungsan Sohn. Elife 2015
5
3
Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands.
Roman Barbalat, Laura Lau, Richard M Locksley, Gregory M Barton. Nat Immunol 2009
Roman Barbalat, Laura Lau, Richard M Locksley, Gregory M Barton. Nat Immunol 2009
3
Mechanism of endosomal TLR inhibition by antimalarial drugs and imidazoquinolines.
Alenka Kuznik, Mojca Bencina, Urban Svajger, Matjaz Jeras, Blaz Rozman, Roman Jerala. J Immunol 2011
Alenka Kuznik, Mojca Bencina, Urban Svajger, Matjaz Jeras, Blaz Rozman, Roman Jerala. J Immunol 2011
3
cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection.
Megan H Orzalli, Nicole M Broekema, Benjamin A Diner, Dustin C Hancks, Nels C Elde, Ileana M Cristea, David M Knipe. Proc Natl Acad Sci U S A 2015
Megan H Orzalli, Nicole M Broekema, Benjamin A Diner, Dustin C Hancks, Nels C Elde, Ileana M Cristea, David M Knipe. Proc Natl Acad Sci U S A 2015
3
Vaccine adjuvants: putting innate immunity to work.
Robert L Coffman, Alan Sher, Robert A Seder. Immunity 2010
Robert L Coffman, Alan Sher, Robert A Seder. Immunity 2010
3
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.