Alexia M Thomas, Nghiem Bui, Jennifer R Perkins, Lisa A Yuva-Paylor, Richard Paylor. Psychopharmacology (Berl) 2012
Times Cited: 69
Times Cited: 69
Times Cited
Times Co-cited
Similarity
The mGluR theory of fragile X mental retardation.
Mark F Bear, Kimberly M Huber, Stephen T Warren. Trends Neurosci 2004
Mark F Bear, Kimberly M Huber, Stephen T Warren. Trends Neurosci 2004
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Correction of fragile X syndrome in mice.
Gül Dölen, Emily Osterweil, B S Shankaranarayana Rao, Gordon B Smith, Benjamin D Auerbach, Sumantra Chattarji, Mark F Bear. Neuron 2007
Gül Dölen, Emily Osterweil, B S Shankaranarayana Rao, Gordon B Smith, Benjamin D Auerbach, Sumantra Chattarji, Mark F Bear. Neuron 2007
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Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP.
Q J Yan, M Rammal, M Tranfaglia, R P Bauchwitz. Neuropharmacology 2005
Q J Yan, M Rammal, M Tranfaglia, R P Bauchwitz. Neuropharmacology 2005
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Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice.
Aubin Michalon, Michael Sidorov, Theresa M Ballard, Laurence Ozmen, Will Spooren, Joseph G Wettstein, Georg Jaeschke, Mark F Bear, Lothar Lindemann. Neuron 2012
Aubin Michalon, Michael Sidorov, Theresa M Ballard, Laurence Ozmen, Will Spooren, Joseph G Wettstein, Georg Jaeschke, Mark F Bear, Lothar Lindemann. Neuron 2012
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Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice.
Femke M S de Vrij, Josien Levenga, Herma C van der Linde, Sebastiaan K Koekkoek, Chris I De Zeeuw, David L Nelson, Ben A Oostra, Rob Willemsen. Neurobiol Dis 2008
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Altered synaptic plasticity in a mouse model of fragile X mental retardation.
Kimberly M Huber, Sean M Gallagher, Stephen T Warren, Mark F Bear. Proc Natl Acad Sci U S A 2002
Kimberly M Huber, Sean M Gallagher, Stephen T Warren, Mark F Bear. Proc Natl Acad Sci U S A 2002
42
Epigenetic modification of the FMR1 gene in fragile X syndrome is associated with differential response to the mGluR5 antagonist AFQ056.
Sébastien Jacquemont, Aurore Curie, Vincent des Portes, Maria Giulia Torrioli, Elizabeth Berry-Kravis, Randi J Hagerman, Feliciano J Ramos, Kim Cornish, Yunsheng He, Charles Paulding,[...]. Sci Transl Med 2011
Sébastien Jacquemont, Aurore Curie, Vincent des Portes, Maria Giulia Torrioli, Elizabeth Berry-Kravis, Randi J Hagerman, Feliciano J Ramos, Kim Cornish, Yunsheng He, Charles Paulding,[...]. Sci Transl Med 2011
36
Mutations causing syndromic autism define an axis of synaptic pathophysiology.
Benjamin D Auerbach, Emily K Osterweil, Mark F Bear. Nature 2011
Benjamin D Auerbach, Emily K Osterweil, Mark F Bear. Nature 2011
34
Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome.
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A pilot open label, single dose trial of fenobam in adults with fragile X syndrome.
E Berry-Kravis, D Hessl, S Coffey, C Hervey, A Schneider, J Yuhas, J Hutchison, M Snape, M Tranfaglia, D V Nguyen,[...]. J Med Genet 2009
E Berry-Kravis, D Hessl, S Coffey, C Hervey, A Schneider, J Yuhas, J Hutchison, M Snape, M Tranfaglia, D V Nguyen,[...]. J Med Genet 2009
27
FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism.
Jennifer C Darnell, Sarah J Van Driesche, Chaolin Zhang, Ka Ying Sharon Hung, Aldo Mele, Claire E Fraser, Elizabeth F Stone, Cynthia Chen, John J Fak, Sung Wook Chi,[...]. Cell 2011
Jennifer C Darnell, Sarah J Van Driesche, Chaolin Zhang, Ka Ying Sharon Hung, Aldo Mele, Claire E Fraser, Elizabeth F Stone, Cynthia Chen, John J Fak, Sung Wook Chi,[...]. Cell 2011
26
Hypersensitivity to mGluR5 and ERK1/2 leads to excessive protein synthesis in the hippocampus of a mouse model of fragile X syndrome.
Emily K Osterweil, Dilja D Krueger, Kimberly Reinhold, Mark F Bear. J Neurosci 2010
Emily K Osterweil, Dilja D Krueger, Kimberly Reinhold, Mark F Bear. J Neurosci 2010
26
Negative allosteric modulation of the mGluR5 receptor reduces repetitive behaviors and rescues social deficits in mouse models of autism.
Jill L Silverman, Daniel G Smith, Stacey J Sukoff Rizzo, Michael N Karras, Sarah M Turner, Seda S Tolu, Dianne K Bryce, Deborah L Smith, Kari Fonseca, Robert H Ring,[...]. Sci Transl Med 2012
Jill L Silverman, Daniel G Smith, Stacey J Sukoff Rizzo, Michael N Karras, Sarah M Turner, Seda S Tolu, Dianne K Bryce, Deborah L Smith, Kari Fonseca, Robert H Ring,[...]. Sci Transl Med 2012
26
Genetic reduction of group 1 metabotropic glutamate receptors alters select behaviors in a mouse model for fragile X syndrome.
Alexia M Thomas, Nghiem Bui, Deanna Graham, Jennifer R Perkins, Lisa A Yuva-Paylor, Richard Paylor. Behav Brain Res 2011
Alexia M Thomas, Nghiem Bui, Deanna Graham, Jennifer R Perkins, Lisa A Yuva-Paylor, Richard Paylor. Behav Brain Res 2011
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Fmr1 knockout mice: a model to study fragile X mental retardation. The Dutch-Belgian Fragile X Consortium.
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Minocycline promotes dendritic spine maturation and improves behavioural performance in the fragile X mouse model.
T V Bilousova, L Dansie, M Ngo, J Aye, J R Charles, D W Ethell, I M Ethell. J Med Genet 2009
T V Bilousova, L Dansie, M Ngo, J Aye, J R Charles, D W Ethell, I M Ethell. J Med Genet 2009
24
Reversal of disease-related pathologies in the fragile X mouse model by selective activation of GABAB receptors with arbaclofen.
Christina Henderson, Lasani Wijetunge, Mika Nakamoto Kinoshita, Matthew Shumway, Rebecca S Hammond, Friso R Postma, Christopher Brynczka, Roger Rush, Alexia Thomas, Richard Paylor,[...]. Sci Transl Med 2012
Christina Henderson, Lasani Wijetunge, Mika Nakamoto Kinoshita, Matthew Shumway, Rebecca S Hammond, Friso R Postma, Christopher Brynczka, Roger Rush, Alexia Thomas, Richard Paylor,[...]. Sci Transl Med 2012
24
Repetitive self-grooming behavior in the BTBR mouse model of autism is blocked by the mGluR5 antagonist MPEP.
Jill L Silverman, Seda S Tolu, Charlotte L Barkan, Jacqueline N Crawley. Neuropsychopharmacology 2010
Jill L Silverman, Seda S Tolu, Charlotte L Barkan, Jacqueline N Crawley. Neuropsychopharmacology 2010
23
Altered anxiety-related and social behaviors in the Fmr1 knockout mouse model of fragile X syndrome.
C M Spencer, O Alekseyenko, E Serysheva, L A Yuva-Paylor, R Paylor. Genes Brain Behav 2005
C M Spencer, O Alekseyenko, E Serysheva, L A Yuva-Paylor, R Paylor. Genes Brain Behav 2005
21
AFQ056, a new mGluR5 antagonist for treatment of fragile X syndrome.
Josien Levenga, Shigemi Hayashi, Femke M S de Vrij, Sebastiaan K Koekkoek, Herma C van der Linde, Ingeborg Nieuwenhuizen, Cheng Song, Ronald A M Buijsen, Andreea S Pop, Baltazar Gomezmancilla,[...]. Neurobiol Dis 2011
Josien Levenga, Shigemi Hayashi, Femke M S de Vrij, Sebastiaan K Koekkoek, Herma C van der Linde, Ingeborg Nieuwenhuizen, Cheng Song, Ronald A M Buijsen, Andreea S Pop, Baltazar Gomezmancilla,[...]. Neurobiol Dis 2011
21
Fragile X mice develop sensory hyperreactivity to auditory stimuli.
L Chen, M Toth. Neuroscience 2001
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Dysregulation of mTOR signaling in fragile X syndrome.
Ali Sharma, Charles A Hoeffer, Yukihiro Takayasu, Takahiro Miyawaki, Sean M McBride, Eric Klann, R Suzanne Zukin. J Neurosci 2010
Ali Sharma, Charles A Hoeffer, Yukihiro Takayasu, Takahiro Miyawaki, Sean M McBride, Eric Klann, R Suzanne Zukin. J Neurosci 2010
20
Lithium ameliorates altered glycogen synthase kinase-3 and behavior in a mouse model of fragile X syndrome.
Christopher J Yuskaitis, Marjelo A Mines, Margaret K King, J David Sweatt, Courtney A Miller, Richard S Jope. Biochem Pharmacol 2010
Christopher J Yuskaitis, Marjelo A Mines, Margaret K King, J David Sweatt, Courtney A Miller, Richard S Jope. Biochem Pharmacol 2010
20
Early continuous inhibition of group 1 mGlu signaling partially rescues dendritic spine abnormalities in the Fmr1 knockout mouse model for fragile X syndrome.
Tao Su, Hong-Xing Fan, Tao Jiang, Wei-Wen Sun, Wei-Yi Den, Mei-Mei Gao, Sheng-Qiang Chen, Qi-Hua Zhao, Yong-Hong Yi. Psychopharmacology (Berl) 2011
Tao Su, Hong-Xing Fan, Tao Jiang, Wei-Wen Sun, Wei-Yi Den, Mei-Mei Gao, Sheng-Qiang Chen, Qi-Hua Zhao, Yong-Hong Yi. Psychopharmacology (Berl) 2011
28
Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors.
Mika Nakamoto, Vijayalaxmi Nalavadi, Michael P Epstein, Usha Narayanan, Gary J Bassell, Stephen T Warren. Proc Natl Acad Sci U S A 2007
Mika Nakamoto, Vijayalaxmi Nalavadi, Michael P Epstein, Usha Narayanan, Gary J Bassell, Stephen T Warren. Proc Natl Acad Sci U S A 2007
20
Toward fulfilling the promise of molecular medicine in fragile X syndrome.
Dilja D Krueger, Mark F Bear. Annu Rev Med 2011
Dilja D Krueger, Mark F Bear. Annu Rev Med 2011
20
Effects of STX209 (arbaclofen) on neurobehavioral function in children and adults with fragile X syndrome: a randomized, controlled, phase 2 trial.
Elizabeth M Berry-Kravis, David Hessl, Barbara Rathmell, Peter Zarevics, Maryann Cherubini, Karen Walton-Bowen, Yi Mu, Danh V Nguyen, Joseph Gonzalez-Heydrich, Paul P Wang,[...]. Sci Transl Med 2012
Elizabeth M Berry-Kravis, David Hessl, Barbara Rathmell, Peter Zarevics, Maryann Cherubini, Karen Walton-Bowen, Yi Mu, Danh V Nguyen, Joseph Gonzalez-Heydrich, Paul P Wang,[...]. Sci Transl Med 2012
20
Rescue of dendritic spine phenotype in Fmr1 KO mice with the mGluR5 antagonist AFQ056/Mavoglurant.
Andreea S Pop, Josien Levenga, Celine E F de Esch, Ronald A M Buijsen, Ingeborg M Nieuwenhuizen, Tracy Li, Aaron Isaacs, Fabrizio Gasparini, Ben A Oostra, Rob Willemsen. Psychopharmacology (Berl) 2014
Andreea S Pop, Josien Levenga, Celine E F de Esch, Ronald A M Buijsen, Ingeborg M Nieuwenhuizen, Tracy Li, Aaron Isaacs, Fabrizio Gasparini, Ben A Oostra, Rob Willemsen. Psychopharmacology (Berl) 2014
23
Alterations in the auditory startle response in Fmr1 targeted mutant mouse models of fragile X syndrome.
Darci M Nielsen, William J Derber, Danielle A McClellan, Linda S Crnic. Brain Res 2002
Darci M Nielsen, William J Derber, Danielle A McClellan, Linda S Crnic. Brain Res 2002
18
Modulation of behavioral phenotypes by a muscarinic M1 antagonist in a mouse model of fragile X syndrome.
Surabi Veeraragavan, Nghiem Bui, Jennie R Perkins, Lisa A Yuva-Paylor, Randall L Carpenter, Richard Paylor. Psychopharmacology (Berl) 2011
Surabi Veeraragavan, Nghiem Bui, Jennie R Perkins, Lisa A Yuva-Paylor, Randall L Carpenter, Richard Paylor. Psychopharmacology (Berl) 2011
29
Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome.
Dilja D Krueger, Emily K Osterweil, Stephanie P Chen, Lynne D Tye, Mark F Bear. Proc Natl Acad Sci U S A 2011
Dilja D Krueger, Emily K Osterweil, Stephanie P Chen, Lynne D Tye, Mark F Bear. Proc Natl Acad Sci U S A 2011
18
Modifying behavioral phenotypes in Fmr1KO mice: genetic background differences reveal autistic-like responses.
Corinne M Spencer, Olga Alekseyenko, Shannon M Hamilton, Alexia M Thomas, Ekaterina Serysheva, Lisa A Yuva-Paylor, Richard Paylor. Autism Res 2011
Corinne M Spencer, Olga Alekseyenko, Shannon M Hamilton, Alexia M Thomas, Ekaterina Serysheva, Lisa A Yuva-Paylor, Richard Paylor. Autism Res 2011
18
Chronic administration of AFQ056/Mavoglurant restores social behaviour in Fmr1 knockout mice.
Ilse Gantois, Andreea S Pop, Celine E F de Esch, Ronald A M Buijsen, Tine Pooters, Baltazar Gomez-Mancilla, Fabrizio Gasparini, Ben A Oostra, Rudi D'Hooge, Rob Willemsen. Behav Brain Res 2013
Ilse Gantois, Andreea S Pop, Celine E F de Esch, Ronald A M Buijsen, Tine Pooters, Baltazar Gomez-Mancilla, Fabrizio Gasparini, Ben A Oostra, Rudi D'Hooge, Rob Willemsen. Behav Brain Res 2013
19
Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function.
Gary J Bassell, Stephen T Warren. Neuron 2008
Gary J Bassell, Stephen T Warren. Neuron 2008
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Behavioral and neuroanatomical characterization of the Fmr1 knockout mouse.
Yann S Mineur, Frans Sluyter, Sanne de Wit, Ben A Oostra, Wim E Crusio. Hippocampus 2002
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The effect of an mGluR5 inhibitor on procedural memory and avoidance discrimination impairments in Fmr1 KO mice.
M F Vinueza Veloz, R A M Buijsen, R Willemsen, A Cupido, L W J Bosman, S K E Koekkoek, J W Potters, B A Oostra, C I De Zeeuw. Genes Brain Behav 2012
M F Vinueza Veloz, R A M Buijsen, R Willemsen, A Cupido, L W J Bosman, S K E Koekkoek, J W Potters, B A Oostra, C I De Zeeuw. Genes Brain Behav 2012
26
mGluR5-antagonist mediated reversal of elevated stereotyped, repetitive behaviors in the VPA model of autism.
Mili V Mehta, Michael J Gandal, Steven J Siegel. PLoS One 2011
Mili V Mehta, Michael J Gandal, Steven J Siegel. PLoS One 2011
17
Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety.
Alexia Thomas, April Burant, Nghiem Bui, Deanna Graham, Lisa A Yuva-Paylor, Richard Paylor. Psychopharmacology (Berl) 2009
Alexia Thomas, April Burant, Nghiem Bui, Deanna Graham, Lisa A Yuva-Paylor, Richard Paylor. Psychopharmacology (Berl) 2009
17
Increased GABA(B) receptor-mediated signaling reduces the susceptibility of fragile X knockout mice to audiogenic seizures.
Laura K K Pacey, Scott P Heximer, David R Hampson. Mol Pharmacol 2009
Laura K K Pacey, Scott P Heximer, David R Hampson. Mol Pharmacol 2009
17
Sensorimotor gating abnormalities in young males with fragile X syndrome and Fmr1-knockout mice.
P W Frankland, Y Wang, B Rosner, T Shimizu, B W Balleine, E M Dykens, E M Ornitz, A J Silva. Mol Psychiatry 2004
P W Frankland, Y Wang, B Rosner, T Shimizu, B W Balleine, E M Dykens, E M Ornitz, A J Silva. Mol Psychiatry 2004
15
Molecular mechanisms of fragile X syndrome: a twenty-year perspective.
Michael R Santoro, Steven M Bray, Stephen T Warren. Annu Rev Pathol 2012
Michael R Santoro, Steven M Bray, Stephen T Warren. Annu Rev Pathol 2012
15
Elevated glycogen synthase kinase-3 activity in Fragile X mice: key metabolic regulator with evidence for treatment potential.
Wenzhong William Min, Christopher J Yuskaitis, Qijiang Yan, Christopher Sikorski, Shengqiang Chen, Richard S Jope, Robert P Bauchwitz. Neuropharmacology 2009
Wenzhong William Min, Christopher J Yuskaitis, Qijiang Yan, Christopher Sikorski, Shengqiang Chen, Richard S Jope, Robert P Bauchwitz. Neuropharmacology 2009
15
Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: a quantitative examination.
S A Irwin, B Patel, M Idupulapati, J B Harris, R A Crisostomo, B P Larsen, F Kooy, P J Willems, P Cras, P B Kozlowski,[...]. Am J Med Genet 2001
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15
Minocycline treatment reverses ultrasonic vocalization production deficit in a mouse model of Fragile X Syndrome.
Sarah E Rotschafer, Michael S Trujillo, Lorraine E Dansie, Iryna M Ethell, Khaleel A Razak. Brain Res 2012
Sarah E Rotschafer, Michael S Trujillo, Lorraine E Dansie, Iryna M Ethell, Khaleel A Razak. Brain Res 2012
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Object recognition impairment in Fmr1 knockout mice is reversed by amphetamine: involvement of dopamine in the medial prefrontal cortex.
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Genetic reduction of muscarinic M4 receptor modulates analgesic response and acoustic startle response in a mouse model of fragile X syndrome (FXS).
Surabi Veeraragavan, Deanna Graham, Nghiem Bui, Lisa A Yuva-Paylor, Jürgen Wess, Richard Paylor. Behav Brain Res 2012
Surabi Veeraragavan, Deanna Graham, Nghiem Bui, Lisa A Yuva-Paylor, Jürgen Wess, Richard Paylor. Behav Brain Res 2012
31
A randomized double-blind, placebo-controlled trial of minocycline in children and adolescents with fragile x syndrome.
Mary Jacena S Leigh, Danh V Nguyen, Yi Mu, Tri I Winarni, Andrea Schneider, Tasleem Chechi, Jonathan Polussa, Paul Doucet, Flora Tassone, Susan M Rivera,[...]. J Dev Behav Pediatr 2013
Mary Jacena S Leigh, Danh V Nguyen, Yi Mu, Tri I Winarni, Andrea Schneider, Tasleem Chechi, Jonathan Polussa, Paul Doucet, Flora Tassone, Susan M Rivera,[...]. J Dev Behav Pediatr 2013
15
Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486.
Bridget M Dolan, Sergio G Duron, David A Campbell, Benedikt Vollrath, B S Shankaranarayana Rao, Hui-Yeon Ko, Gregory G Lin, Arvind Govindarajan, Se-Young Choi, Susumu Tonegawa. Proc Natl Acad Sci U S A 2013
Bridget M Dolan, Sergio G Duron, David A Campbell, Benedikt Vollrath, B S Shankaranarayana Rao, Hui-Yeon Ko, Gregory G Lin, Arvind Govindarajan, Se-Young Choi, Susumu Tonegawa. Proc Natl Acad Sci U S A 2013
15
Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile X syndrome.
Christina Gross, Mika Nakamoto, Xiaodi Yao, Chi-Bun Chan, So Y Yim, Keqiang Ye, Stephen T Warren, Gary J Bassell. J Neurosci 2010
Christina Gross, Mika Nakamoto, Xiaodi Yao, Chi-Bun Chan, So Y Yim, Keqiang Ye, Stephen T Warren, Gary J Bassell. J Neurosci 2010
14
Dissociation of social and nonsocial anxiety in a mouse model of fragile X syndrome.
Zhong-Hua Liu, Carolyn Beebe Smith. Neurosci Lett 2009
Zhong-Hua Liu, Carolyn Beebe Smith. Neurosci Lett 2009
14
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.