A citation-based method for searching scientific literature

Luisa Izzi, Martin Lévesque, Steves Morin, Dominique Laniel, Brian C Wilkes, Frédéric Mille, Robert S Krauss, Andrew P McMahon, Benjamin L Allen, Frédéric Charron. Dev Cell 2011
Times Cited: 162







List of co-cited articles
1230 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function.
Benjamin L Allen, Jane Y Song, Luisa Izzi, Irene W Althaus, Jong-Sun Kang, Frédéric Charron, Robert S Krauss, Andrew P McMahon. Dev Cell 2011
189
64

The mechanisms of Hedgehog signalling and its roles in development and disease.
James Briscoe, Pascal P Thérond. Nat Rev Mol Cell Biol 2013
979
38

The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice.
Toyoaki Tenzen, Benjamin L Allen, Francesca Cole, Jong-Sun Kang, Robert S Krauss, Andrew P McMahon. Dev Cell 2006
266
34


Gas1 extends the range of Hedgehog action by facilitating its signaling.
David C Martinelli, Chen-Ming Fan. Genes Dev 2007
152
28

Boc is a receptor for sonic hedgehog in the guidance of commissural axons.
Ami Okada, Frédéric Charron, Steves Morin, David S Shin, Karen Wong, Pierre J Fabre, Marc Tessier-Lavigne, Susan K McConnell. Nature 2006
213
27

Patched1 regulates hedgehog signaling at the primary cilium.
Rajat Rohatgi, Ljiljana Milenkovic, Matthew P Scott. Science 2007
954
23

Patched acts catalytically to suppress the activity of Smoothened.
J Taipale, M K Cooper, T Maiti, P A Beachy. Nature 2002
574
20


Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function.
C Chiang, Y Litingtung, E Lee, K E Young, J L Corden, H Westphal, P A Beachy. Nature 1996
19

Altered neural cell fates and medulloblastoma in mouse patched mutants.
L V Goodrich, L Milenković, K M Higgins, M P Scott. Science 1997
18

Gas1 is a modifier for holoprosencephaly and genetically interacts with sonic hedgehog.
Maisa Seppala, Michael J Depew, David C Martinelli, Chen-Ming Fan, Paul T Sharpe, Martyn T Cobourne. J Clin Invest 2007
97
18

Mutations in CDON, encoding a hedgehog receptor, result in holoprosencephaly and defective interactions with other hedgehog receptors.
Gyu-Un Bae, Sabina Domené, Erich Roessler, Karen Schachter, Jong-Sun Kang, Maximilian Muenke, Robert S Krauss. Am J Hum Genet 2011
91
19

Vertebrate Smoothened functions at the primary cilium.
Kevin C Corbit, Pia Aanstad, Veena Singla, Andrew R Norman, Didier Y R Stainier, Jeremy F Reiter. Nature 2005
18


The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla.
Jason S McLellan, Xiaoyan Zheng, Glenn Hauk, Rodolfo Ghirlando, Philip A Beachy, Daniel J Leahy. Nature 2008
113
18

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog.
D M Stone, M Hynes, M Armanini, T A Swanson, Q Gu, R L Johnson, M P Scott, D Pennica, A Goddard, H Phillips,[...]. Nature 1996
894
18

Identification of a palmitic acid-modified form of human Sonic hedgehog.
R B Pepinsky, C Zeng, D Wen, P Rayhorn, D P Baker, K P Williams, S A Bixler, C M Ambrose, E A Garber, K Miatkowski,[...]. J Biol Chem 1998
527
18

Essential role for ligand-dependent feedback antagonism of vertebrate hedgehog signaling by PTCH1, PTCH2 and HHIP1 during neural patterning.
Alexander M Holtz, Kevin A Peterson, Yuichi Nishi, Steves Morin, Jane Y Song, Frédéric Charron, Andrew P McMahon, Benjamin L Allen. Development 2013
50
32



Mutations affecting segment number and polarity in Drosophila.
C Nüsslein-Volhard, E Wieschaus. Nature 1980
14

Boc modifies the holoprosencephaly spectrum of Cdo mutant mice.
Wei Zhang, Mingi Hong, Gyu-un Bae, Jong-Sun Kang, Robert S Krauss. Dis Model Mech 2011
47
29


Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling.
Sigrid Nachtergaele, Daniel M Whalen, Laurel K Mydock, Zhonghua Zhao, Tomas Malinauskas, Kathiresan Krishnan, Philip W Ingham, Douglas F Covey, Christian Siebold, Rajat Rohatgi. Elife 2013
107
14

Interactions between Hedgehog proteins and their binding partners come into view.
Philip A Beachy, Sarah G Hymowitz, Robert A Lazarus, Daniel J Leahy, Christian Siebold. Genes Dev 2010
128
14

Biochemical evidence that patched is the Hedgehog receptor.
V Marigo, R A Davey, Y Zuo, J M Cunningham, C J Tabin. Nature 1996
665
14

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity.
Y Echelard, D J Epstein, B St-Jacques, L Shen, J Mohler, J A McMahon, A P McMahon. Cell 1993
14

Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling.
Pengxiang Huang, Daniel Nedelcu, Miyako Watanabe, Cindy Jao, Youngchang Kim, Jing Liu, Adrian Salic. Cell 2016
192
14


BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation.
Jong-Sun Kang, Philip J Mulieri, Yulan Hu, Lavinia Taliana, Robert S Krauss. EMBO J 2002
115
13

The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling.
Saikat Mukhopadhyay, Xiaohui Wen, Navneet Ratti, Alexander Loktev, Linda Rangell, Suzie J Scales, Peter K Jackson. Cell 2013
266
12

The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance.
Frédéric Charron, Elke Stein, Juhee Jeong, Andrew P McMahon, Marc Tessier-Lavigne. Cell 2003
496
12

Small molecule modulation of Smoothened activity.
James K Chen, Jussi Taipale, Keith E Young, Tapan Maiti, Philip A Beachy. Proc Natl Acad Sci U S A 2002
745
12

Gli proteins in development and disease.
Chi-Chung Hui, Stephane Angers. Annu Rev Cell Dev Biol 2011
437
12

Hedgehog pathway modulation by multiple lipid binding sites on the smoothened effector of signal response.
Benjamin R Myers, Navdar Sever, Yong Chun Chong, James Kim, Jitendra D Belani, Scott Rychnovsky, J Fernando Bazan, Philip A Beachy. Dev Cell 2013
123
12


Activating Smoothened mutations in sporadic basal-cell carcinoma.
J Xie, M Murone, S M Luoh, A Ryan, Q Gu, C Zhang, J M Bonifas, C W Lam, M Hynes, A Goddard,[...]. Nature 1998
986
12

Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates.
Miao-Hsueh Chen, Ya-Jun Li, Takatoshi Kawakami, Shan-Mei Xu, Pao-Tien Chuang. Genes Dev 2004
250
12

Developmental roles and clinical significance of hedgehog signaling.
Andrew P McMahon, Philip W Ingham, Clifford J Tabin. Curr Top Dev Biol 2003
661
12

The primary cilium: a signalling centre during vertebrate development.
Sarah C Goetz, Kathryn V Anderson. Nat Rev Genet 2010
12

Dispatched and scube mediate the efficient secretion of the cholesterol-modified hedgehog ligand.
Hanna Tukachinsky, Ryan P Kuzmickas, Cindy Y Jao, Jing Liu, Adrian Salic. Cell Rep 2012
127
12

Structural basis of Smoothened regulation by its extracellular domains.
Eamon F X Byrne, Ria Sircar, Paul S Miller, George Hedger, Giovanni Luchetti, Sigrid Nachtergaele, Mark D Tully, Laurel Mydock-McGrane, Douglas F Covey, Robert P Rambo,[...]. Nature 2016
199
12

Structure of the human smoothened receptor bound to an antitumour agent.
Chong Wang, Huixian Wu, Vsevolod Katritch, Gye Won Han, Xi-Ping Huang, Wei Liu, Fai Yiu Siu, Bryan L Roth, Vadim Cherezov, Raymond C Stevens. Nature 2013
334
11


Hedgehog signal transduction by Smoothened: pharmacologic evidence for a 2-step activation process.
Rajat Rohatgi, Ljiljana Milenkovic, Ryan B Corcoran, Matthew P Scott. Proc Natl Acad Sci U S A 2009
201
11


Oxysterol binding to the extracellular domain of Smoothened in Hedgehog signaling.
Daniel Nedelcu, Jing Liu, Yangqing Xu, Cindy Jao, Adrian Salic. Nat Chem Biol 2013
130
11

Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened.
Yongbin Chen, Noriaki Sasai, Guoqiang Ma, Tao Yue, Jianhang Jia, James Briscoe, Jin Jiang. PLoS Biol 2011
139
11

Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP.
Benjamin Bishop, A Radu Aricescu, Karl Harlos, Chris A O'Callaghan, E Yvonne Jones, Christian Siebold. Nat Struct Mol Biol 2009
89
12


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.