Efrat Ozeri-Galai, Ronald Lebofsky, Ayelet Rahat, Assaf C Bester, Aaron Bensimon, Batsheva Kerem. Mol Cell 2011
Times Cited: 126
Times Cited: 126
Times Cited
Times Co-cited
Similarity
Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site.
Anne Letessier, Gaël A Millot, Stéphane Koundrioukoff, Anne-Marie Lachagès, Nicolas Vogt, R Scott Hansen, Bernard Malfoy, Olivier Brison, Michelle Debatisse. Nature 2011
Anne Letessier, Gaël A Millot, Stéphane Koundrioukoff, Anne-Marie Lachagès, Nicolas Vogt, R Scott Hansen, Bernard Malfoy, Olivier Brison, Michelle Debatisse. Nature 2011
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Collisions between replication and transcription complexes cause common fragile site instability at the longest human genes.
Anne Helmrich, Monica Ballarino, Laszlo Tora. Mol Cell 2011
Anne Helmrich, Monica Ballarino, Laszlo Tora. Mol Cell 2011
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Common fragile site profiling in epithelial and erythroid cells reveals that most recurrent cancer deletions lie in fragile sites hosting large genes.
Benoît Le Tallec, Gaël Armel Millot, Marion Esther Blin, Olivier Brison, Bernard Dutrillaux, Michelle Debatisse. Cell Rep 2013
Benoît Le Tallec, Gaël Armel Millot, Marion Esther Blin, Olivier Brison, Bernard Dutrillaux, Michelle Debatisse. Cell Rep 2013
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Molecular basis for expression of common and rare fragile sites.
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Identification of early replicating fragile sites that contribute to genome instability.
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Molecular profiling of common fragile sites in human fibroblasts.
Benoî Le Tallec, Bernard Dutrillaux, Anne-Marie Lachages, Gael Armel Millot, Olivier Brison, Michelle Debatisse. Nat Struct Mol Biol 2011
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DNA polymerase alpha inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes.
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An AT-rich sequence in human common fragile site FRA16D causes fork stalling and chromosome breakage in S. cerevisiae.
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Common fragile sites: mechanisms of instability revisited.
Michelle Debatisse, Benoît Le Tallec, Anne Letessier, Bernard Dutrillaux, Olivier Brison. Trends Genet 2012
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Nucleotide deficiency promotes genomic instability in early stages of cancer development.
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Replication of a common fragile site, FRA3B, occurs late in S phase and is delayed further upon induction: implications for the mechanism of fragile site induction.
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Replication stress induces sister-chromatid bridging at fragile site loci in mitosis.
Kok Lung Chan, Timea Palmai-Pallag, Songmin Ying, Ian D Hickson. Nat Cell Biol 2009
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Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions.
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Replication stress activates DNA repair synthesis in mitosis.
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Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication.
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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis.
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ERCC1 and MUS81-EME1 promote sister chromatid separation by processing late replication intermediates at common fragile sites during mitosis.
Valeria Naim, Therese Wilhelm, Michelle Debatisse, Filippo Rosselli. Nat Cell Biol 2013
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MUS81 promotes common fragile site expression.
Songmin Ying, Sheroy Minocherhomji, Kok Lung Chan, Timea Palmai-Pallag, Wai Kit Chu, Theresa Wass, Hocine W Mankouri, Ying Liu, Ian D Hickson. Nat Cell Biol 2013
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An oncogene-induced DNA damage model for cancer development.
Thanos D Halazonetis, Vassilis G Gorgoulis, Jiri Bartek. Science 2008
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53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress.
Claudia Lukas, Velibor Savic, Simon Bekker-Jensen, Carsten Doil, Beate Neumann, Ronni Sølvhøj Pedersen, Merete Grøfte, Kok Lung Chan, Ian David Hickson, Jiri Bartek,[...]. Nat Cell Biol 2011
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Increased replication initiation and conflicts with transcription underlie Cyclin E-induced replication stress.
R M Jones, O Mortusewicz, I Afzal, M Lorvellec, P García, T Helleday, E Petermann. Oncogene 2013
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Oncogene-induced replication stress preferentially targets common fragile sites in preneoplastic lesions. A genome-wide study.
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Break-induced replication repair of damaged forks induces genomic duplications in human cells.
Lorenzo Costantino, Sotirios K Sotiriou, Juha K Rantala, Simon Magin, Emil Mladenov, Thomas Helleday, James E Haber, George Iliakis, Olli P Kallioniemi, Thanos D Halazonetis. Science 2014
Lorenzo Costantino, Sotirios K Sotiriou, Juha K Rantala, Simon Magin, Emil Mladenov, Thomas Helleday, James E Haber, George Iliakis, Olli P Kallioniemi, Thanos D Halazonetis. Science 2014
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DNA structure and the Werner protein modulate human DNA polymerase delta-dependent replication dynamics within the common fragile site FRA16D.
Sandeep N Shah, Patricia L Opresko, Xiao Meng, Marietta Y W T Lee, Kristin A Eckert. Nucleic Acids Res 2010
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DNA synthesis by Pol η promotes fragile site stability by preventing under-replicated DNA in mitosis.
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Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints.
Jirina Bartkova, Nousin Rezaei, Michalis Liontos, Panagiotis Karakaidos, Dimitris Kletsas, Natalia Issaeva, Leandros-Vassilios F Vassiliou, Evangelos Kolettas, Katerina Niforou, Vassilis C Zoumpourlis,[...]. Nature 2006
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20
Oncogenes create a unique landscape of fragile sites.
Karin Miron, Tamar Golan-Lev, Raz Dvir, Eyal Ben-David, Batsheva Kerem. Nat Commun 2015
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FANCD2 Facilitates Replication through Common Fragile Sites.
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Advaitha Madireddy, Settapong T Kosiyatrakul, Rebecca A Boisvert, Emilia Herrera-Moyano, María L García-Rubio, Jeannine Gerhardt, Elizabeth A Vuono, Nichole Owen, Zi Yan, Susan Olson,[...]. Mol Cell 2016
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Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress.
Xin Quan Ge, Dean A Jackson, J Julian Blow. Genes Dev 2007
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Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair.
Eva Petermann, Manuel Luís Orta, Natalia Issaeva, Niklas Schultz, Thomas Helleday. Mol Cell 2010
Eva Petermann, Manuel Luís Orta, Natalia Issaeva, Niklas Schultz, Thomas Helleday. Mol Cell 2010
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Large transcription units unify copy number variants and common fragile sites arising under replication stress.
Thomas E Wilson, Martin F Arlt, So Hae Park, Sountharia Rajendran, Michelle Paulsen, Mats Ljungman, Thomas W Glover. Genome Res 2015
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ATR regulates fragile site stability.
Anne M Casper, Paul Nghiem, Martin F Arlt, Thomas W Glover. Cell 2002
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How dormant origins promote complete genome replication.
J Julian Blow, Xin Quan Ge, Dean A Jackson. Trends Biochem Sci 2011
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Causes and consequences of replication stress.
Michelle K Zeman, Karlene A Cimprich. Nat Cell Biol 2014
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Replication stress links structural and numerical cancer chromosomal instability.
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Replication dynamics at common fragile site FRA6E.
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Fragile sites in cancer: more than meets the eye.
Thomas W Glover, Thomas E Wilson, Martin F Arlt. Nat Rev Cancer 2017
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Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by the cloning of a simian virus 40 integration site.
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The complex basis underlying common fragile site instability in cancer.
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The landscape of somatic copy-number alteration across human cancers.
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Stalled fork rescue via dormant replication origins in unchallenged S phase promotes proper chromosome segregation and tumor suppression.
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The Fanconi anemia pathway is required for the DNA replication stress response and for the regulation of common fragile site stability.
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Deregulation of cyclin E in human cells interferes with prereplication complex assembly.
Susanna Ekholm-Reed, Juan Méndez, Donato Tedesco, Anders Zetterberg, Bruce Stillman, Steven I Reed. J Cell Biol 2004
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RAD52 Facilitates Mitotic DNA Synthesis Following Replication Stress.
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Common fragile sites are characterized by histone hypoacetylation.
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Replication fork stalling at natural impediments.
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Secondary structure formation and DNA instability at fragile site FRA16B.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.