A citation-based method for searching scientific literature

D A Dougan, D Micevski, K N Truscott. Biochim Biophys Acta 2012
Times Cited: 84







List of co-cited articles
859 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


The N-end rule pathway and regulation by proteolysis.
Alexander Varshavsky. Protein Sci 2011
436
71


The N-end rule pathway.
Takafumi Tasaki, Shashikanth M Sriram, Kyong Soo Park, Yong Tae Kwon. Annu Rev Biochem 2012
245
48

N-terminal acetylation of cellular proteins creates specific degradation signals.
Cheol-Sang Hwang, Anna Shemorry, Alexander Varshavsky. Science 2010
431
44

The N-end rule in bacteria.
J W Tobias, T E Shrader, G Rocap, A Varshavsky. Science 1991
420
33

The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments.
Konstantin I Piatkov, Christopher S Brower, Alexander Varshavsky. Proc Natl Acad Sci U S A 2012
98
33

The eukaryotic N-end rule pathway: conserved mechanisms and diverse functions.
Daniel J Gibbs, Jaume Bacardit, Andreas Bachmair, Michael J Holdsworth. Trends Cell Biol 2014
132
32

The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators.
Rong-Gui Hu, Jun Sheng, Xin Qi, Zhenming Xu, Terry T Takahashi, Alexander Varshavsky. Nature 2005
222
30

Control of protein quality and stoichiometries by N-terminal acetylation and the N-end rule pathway.
Anna Shemorry, Cheol-Sang Hwang, Alexander Varshavsky. Mol Cell 2013
194
30

The N-end rule pathway for regulated proteolysis: prokaryotic and eukaryotic strategies.
Axel Mogk, Ronny Schmidt, Bernd Bukau. Trends Cell Biol 2007
189
29

The N-terminal methionine of cellular proteins as a degradation signal.
Heon-Ki Kim, Ryu-Ryun Kim, Jang-Hyun Oh, Hanna Cho, Alexander Varshavsky, Cheol-Sang Hwang. Cell 2014
115
28

An essential role of N-terminal arginylation in cardiovascular development.
Yong Tae Kwon, Anna S Kashina, Ilia V Davydov, Rong-Gui Hu, Jee Young An, Jai Wha Seo, Fangyong Du, Alexander Varshavsky. Science 2002
243
26

Neurodegeneration-associated protein fragments as short-lived substrates of the N-end rule pathway.
Christopher S Brower, Konstantin I Piatkov, Alexander Varshavsky. Mol Cell 2013
78
28

An N-end rule pathway that recognizes proline and destroys gluconeogenic enzymes.
Shun-Jia Chen, Xia Wu, Brandon Wadas, Jang-Hyun Oh, Alexander Varshavsky. Science 2017
105
25

Discovery of cellular regulation by protein degradation.
Alexander Varshavsky. J Biol Chem 2008
73
27

Glutamine-specific N-terminal amidase, a component of the N-end rule pathway.
Haiqing Wang, Konstantin I Piatkov, Christopher S Brower, Alexander Varshavsky. Mol Cell 2009
64
29


The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases.
Cheol-Sang Hwang, Anna Shemorry, Daniel Auerbach, Alexander Varshavsky. Nat Cell Biol 2010
101
22

Calpain-generated natural protein fragments as short-lived substrates of the N-end rule pathway.
Konstantin I Piatkov, Jang-Hyun Oh, Yuan Liu, Alexander Varshavsky. Proc Natl Acad Sci U S A 2014
58
32

The degradation signal in a short-lived protein.
A Bachmair, A Varshavsky. Cell 1989
355
21

RGS4 and RGS5 are in vivo substrates of the N-end rule pathway.
Min Jae Lee, Takafumi Tasaki, Kayoko Moroi, Jee Young An, Sadao Kimura, Ilia V Davydov, Yong Tae Kwon. Proc Natl Acad Sci U S A 2005
181
21

Ubiquitin fusion technique and related methods.
Alexander Varshavsky. Methods Enzymol 2005
83
20


The plant N-end rule pathway: structure and functions.
Emmanuelle Graciet, Frank Wellmer. Trends Plant Sci 2010
67
25

ClpS is an essential component of the N-end rule pathway in Escherichia coli.
A Erbse, R Schmidt, T Bornemann, J Schneider-Mergener, A Mogk, R Zahn, D A Dougan, B Bukau. Nature 2006
170
20

The auto-generated fragment of the Usp1 deubiquitylase is a physiological substrate of the N-end rule pathway.
Konstantin I Piatkov, Luca Colnaghi, Miklos Békés, Alexander Varshavsky, Tony T Huang. Mol Cell 2012
50
34

Aminoacyl-transferases and the N-end rule pathway of prokaryotic/eukaryotic specificity in a human pathogen.
Emmanuelle Graciet, Rong-Gui Hu, Konstantin Piatkov, Joon Haeng Rhee, Erich M Schwarz, Alexander Varshavsky. Proc Natl Acad Sci U S A 2006
71
23

The N-end rule pathway is a sensor of heme.
Rong-Gui Hu, Haiqing Wang, Zanxian Xia, Alexander Varshavsky. Proc Natl Acad Sci U S A 2008
87
19

Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases.
Woo Suk Choi, Byung-Cheon Jeong, Yoo Jin Joo, Myeong-Ryeol Lee, Joon Kim, Michael J Eck, Hyun Kyu Song. Nat Struct Mol Biol 2010
97
19

Remodeling of a delivery complex allows ClpS-mediated degradation of N-degron substrates.
Izarys Rivera-Rivera, Giselle Román-Hernández, Robert T Sauer, Tania A Baker. Proc Natl Acad Sci U S A 2014
32
50

Structural basis of substrate recognition and specificity in the N-end rule pathway.
Edna Matta-Camacho, Guennadi Kozlov, Flora F Li, Kalle Gehring. Nat Struct Mol Biol 2010
74
20

Protein N-terminal acetyltransferases: when the start matters.
Kristian K Starheim, Kris Gevaert, Thomas Arnesen. Trends Biochem Sci 2012
194
17

Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding.
Hyunjoo Cha-Molstad, Ki Sa Sung, Joonsung Hwang, Kyoung A Kim, Ji Eun Yu, Young Dong Yoo, Jun Min Jang, Dong Hoon Han, Michael Molstad, Jung Gi Kim,[...]. Nat Cell Biol 2015
138
17

The ClpS adaptor mediates staged delivery of N-end rule substrates to the AAA+ ClpAP protease.
Giselle Román-Hernández, Jennifer Y Hou, Robert A Grant, Robert T Sauer, Tania A Baker. Mol Cell 2011
45
31

The molecular basis of N-end rule recognition.
Kevin H Wang, Giselle Roman-Hernandez, Robert A Grant, Robert T Sauer, Tania A Baker. Mol Cell 2008
72
19

AAA+ proteases: ATP-fueled machines of protein destruction.
Robert T Sauer, Tania A Baker. Annu Rev Biochem 2011
489
16

The ubiquitin-proteasome system of Saccharomyces cerevisiae.
Daniel Finley, Helle D Ulrich, Thomas Sommer, Peter Kaiser. Genetics 2012
256
16

Protein N-terminal processing: substrate specificity of Escherichia coli and human methionine aminopeptidases.
Qing Xiao, Feiran Zhang, Benjamin A Nacev, Jun O Liu, Dehua Pei. Biochemistry 2010
107
16

Control of mammalian G protein signaling by N-terminal acetylation and the N-end rule pathway.
Sang-Eun Park, Jeong-Mok Kim, Ok-Hee Seok, Hanna Cho, Brandon Wadas, Seon-Young Kim, Alexander Varshavsky, Cheol-Sang Hwang. Science 2015
88
16

N-degron and C-degron pathways of protein degradation.
Alexander Varshavsky. Proc Natl Acad Sci U S A 2019
204
16


ClpS is the recognition component for Escherichia coli substrates of the N-end rule degradation pathway.
Ronny Schmidt, Regina Zahn, Bernd Bukau, Axel Mogk. Mol Microbiol 2009
63
20

First Things First: Vital Protein Marks by N-Terminal Acetyltransferases.
Henriette Aksnes, Adrian Drazic, Michaël Marie, Thomas Arnesen. Trends Biochem Sci 2016
136
15

Ubiquitin Ligases: Structure, Function, and Regulation.
Ning Zheng, Nitzan Shabek. Annu Rev Biochem 2017
533
15

The N-end rule: functions, mysteries, uses.
A Varshavsky. Proc Natl Acad Sci U S A 1996
661
14

Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome).
Martin Zenker, Julia Mayerle, Markus M Lerch, Andreas Tagariello, Klaus Zerres, Peter R Durie, Matthias Beier, Georg Hülskamp, Celina Guzman, Helga Rehder,[...]. Nat Genet 2005
172
14

PINK1 is degraded through the N-end rule pathway.
Koji Yamano, Richard J Youle. Autophagy 2013
365
14

Formyl-methionine as a degradation signal at the N-termini of bacterial proteins.
Konstantin I Piatkov, Tri T M Vu, Cheol-Sang Hwang, Alexander Varshavsky. Microb Cell 2015
41
29


Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway.
Cheng Dong, Heng Zhang, Li Li, Wolfram Tempel, Peter Loppnau, Jinrong Min. Nat Chem Biol 2018
44
27


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.