A citation-based method for searching scientific literature

Han-Xiang Deng, Wenjie Chen, Seong-Tshool Hong, Kym M Boycott, George H Gorrie, Nailah Siddique, Yi Yang, Faisal Fecto, Yong Shi, Hong Zhai, Hujun Jiang, Makito Hirano, Evadnie Rampersaud, Gerard H Jansen, Sandra Donkervoort, Eileen H Bigio, Benjamin R Brooks, Kaouther Ajroud, Robert L Sufit, Jonathan L Haines, Enrico Mugnaini, Margaret A Pericak-Vance, Teepu Siddique. Nature 2011
Times Cited: 756







List of co-cited articles
2145 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Manuela Neumann, Deepak M Sampathu, Linda K Kwong, Adam C Truax, Matthew C Micsenyi, Thomas T Chou, Jennifer Bruce, Theresa Schuck, Murray Grossman, Christopher M Clark,[...]. Science 2006
41

Mutations of optineurin in amyotrophic lateral sclerosis.
Hirofumi Maruyama, Hiroyuki Morino, Hidefumi Ito, Yuishin Izumi, Hidemasa Kato, Yasuhito Watanabe, Yoshimi Kinoshita, Masaki Kamada, Hiroyuki Nodera, Hidenori Suzuki,[...]. Nature 2010
826
40

SQSTM1 mutations in familial and sporadic amyotrophic lateral sclerosis.
Faisal Fecto, Jianhua Yan, S Pavan Vemula, Erdong Liu, Yi Yang, Wenjie Chen, Jian Guo Zheng, Yong Shi, Nailah Siddique, Hasan Arrat,[...]. Arch Neurol 2011
416
33

Exome sequencing reveals VCP mutations as a cause of familial ALS.
Janel O Johnson, Jessica Mandrioli, Michael Benatar, Yevgeniya Abramzon, Vivianna M Van Deerlin, John Q Trojanowski, J Raphael Gibbs, Maura Brunetti, Susan Gronka, Joanne Wuu,[...]. Neuron 2010
833
31

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS.
Mariely DeJesus-Hernandez, Ian R Mackenzie, Bradley F Boeve, Adam L Boxer, Matt Baker, Nicola J Rutherford, Alexandra M Nicholson, NiCole A Finch, Heather Flynn, Jennifer Adamson,[...]. Neuron 2011
31

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis.
D R Rosen, T Siddique, D Patterson, D A Figlewicz, P Sapp, A Hentati, D Donaldson, J Goto, J P O'Regan, H X Deng. Nature 1993
30

Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6.
Caroline Vance, Boris Rogelj, Tibor Hortobágyi, Kurt J De Vos, Agnes Lumi Nishimura, Jemeen Sreedharan, Xun Hu, Bradley Smith, Deborah Ruddy, Paul Wright,[...]. Science 2009
30

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD.
Alan E Renton, Elisa Majounie, Adrian Waite, Javier Simón-Sánchez, Sara Rollinson, J Raphael Gibbs, Jennifer C Schymick, Hannu Laaksovirta, John C van Swieten, Liisa Myllykangas,[...]. Neuron 2011
29

Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis.
T J Kwiatkowski, D A Bosco, A L Leclerc, E Tamrazian, C R Vanderburg, C Russ, A Davis, J Gilchrist, E J Kasarskis, T Munsat,[...]. Science 2009
26

TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis.
Jemeen Sreedharan, Ian P Blair, Vineeta B Tripathi, Xun Hu, Caroline Vance, Boris Rogelj, Steven Ackerley, Jennifer C Durnall, Kelly L Williams, Emanuele Buratti,[...]. Science 2008
24

UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome.
Roland Hjerpe, John S Bett, Matthew J Keuss, Alexandra Solovyova, Thomas G McWilliams, Clare Johnson, Indrajit Sahu, Joby Varghese, Nicola Wood, Melanie Wightman,[...]. Cell 2016
155
23

Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia.
Axel Freischmidt, Thomas Wieland, Benjamin Richter, Wolfgang Ruf, Veronique Schaeffer, Kathrin Müller, Nicolai Marroquin, Frida Nordin, Annemarie Hübers, Patrick Weydt,[...]. Nat Neurosci 2015
458
22

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways.
Elizabeth T Cirulli, Brittany N Lasseigne, Slavé Petrovski, Peter C Sapp, Patrick A Dion, Claire S Leblond, Julien Couthouis, Yi-Fan Lu, Quanli Wang, Brian J Krueger,[...]. Science 2015
559
20

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS.
Hong Joo Kim, Nam Chul Kim, Yong-Dong Wang, Emily A Scarborough, Jennifer Moore, Zamia Diaz, Kyle S MacLea, Brian Freibaum, Songqing Li, Amandine Molliex,[...]. Nature 2013
841
19

Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis.
Shuo-Chien Ling, Magdalini Polymenidou, Don W Cleveland. Neuron 2013
881
19

Decoding ALS: from genes to mechanism.
J Paul Taylor, Robert H Brown, Don W Cleveland. Nature 2016
850
19

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Tetsuaki Arai, Masato Hasegawa, Haruhiko Akiyama, Kenji Ikeda, Takashi Nonaka, Hiroshi Mori, David Mann, Kuniaki Tsuchiya, Mari Yoshida, Yoshio Hashizume,[...]. Biochem Biophys Res Commun 2006
19

Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification.
Mümine Şentürk, Guang Lin, Zhongyuan Zuo, Dongxue Mao, Emma Watson, Antonios G Mikos, Hugo J Bellen. Nat Cell Biol 2019
57
28

Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein.
Giles D J Watts, Jill Wymer, Margaret J Kovach, Sarju G Mehta, Steven Mumm, Daniel Darvish, Alan Pestronk, Michael P Whyte, Virginia E Kimonis. Nat Genet 2004
940
16

Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS.
Andrew C Elden, Hyung-Jun Kim, Michael P Hart, Alice S Chen-Plotkin, Brian S Johnson, Xiaodong Fang, Maria Armakola, Felix Geser, Robert Greene, Min Min Lu,[...]. Nature 2010
755
15

Deleterious variants of FIG4, a phosphoinositide phosphatase, in patients with ALS.
Clement Y Chow, John E Landers, Sarah K Bergren, Peter C Sapp, Adrienne E Grant, Julie M Jones, Lesley Everett, Guy M Lenk, Diane M McKenna-Yasek, Lois S Weisman,[...]. Am J Hum Genet 2009
272
15

Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation.
Elizabeth J Alexander, Amirhossein Ghanbari Niaki, Tao Zhang, Jaya Sarkar, Yang Liu, Raja Sekhar Nirujogi, Akhilesh Pandey, Sua Myong, Jiou Wang. Proc Natl Acad Sci U S A 2018
46
32


The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome.
M F Kleijnen, A H Shih, P Zhou, S Kumar, R E Soccio, N L Kedersha, G Gill, P M Howley. Mol Cell 2000
294
15

ALS Genes in the Genomic Era and their Implications for FTD.
Hung Phuoc Nguyen, Christine Van Broeckhoven, Julie van der Zee. Trends Genet 2018
119
14

Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy.
Cara Rothenberg, Deepa Srinivasan, Leann Mah, Susmita Kaushik, Corrine M Peterhoff, Janet Ugolino, Shengyun Fang, Ana Maria Cuervo, Ralph A Nixon, Mervyn J Monteiro. Hum Mol Genet 2010
159
14

PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation.
Elsa-Noah N'Diaye, Kimberly K Kajihara, Ivy Hsieh, Hiroshi Morisaki, Jayanta Debnath, Eric J Brown. EMBO Rep 2009
207
14

Whole-genome sequencing reveals important role for TBK1 and OPTN mutations in frontotemporal lobar degeneration without motor neuron disease.
Cyril Pottier, Kevin F Bieniek, NiCole Finch, Maartje van de Vorst, Matt Baker, Ralph Perkersen, Patricia Brown, Thomas Ravenscroft, Marka van Blitterswijk, Alexandra M Nicholson,[...]. Acta Neuropathol 2015
197
14

Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS-FTD-linked UBQLN2 mutations.
Nhat T T Le, Lydia Chang, Irina Kovlyagina, Polymnia Georgiou, Nathaniel Safren, Kerstin E Braunstein, Mark D Kvarta, Adam M Van Dyke, Tara A LeGates, Thomas Philips,[...]. Proc Natl Acad Sci U S A 2016
53
26

Ubiquitin Modulates Liquid-Liquid Phase Separation of UBQLN2 via Disruption of Multivalent Interactions.
Thuy P Dao, Regina-Maria Kolaitis, Hong Joo Kim, Kevin O'Donovan, Brian Martyniak, Erica Colicino, Heidi Hehnly, J Paul Taylor, Carlos A Castañeda. Mol Cell 2018
108
14

Protein aggregation in amyotrophic lateral sclerosis.
Anna M Blokhuis, Ewout J N Groen, Max Koppers, Leonard H van den Berg, R Jeroen Pasterkamp. Acta Neuropathol 2013
279
13

Amyotrophic Lateral Sclerosis.
Robert H Brown, Ammar Al-Chalabi. N Engl J Med 2017
550
13

UBQLN2/ubiquilin 2 mutation and pathology in familial amyotrophic lateral sclerosis.
Kelly L Williams, Sadaf T Warraich, Shu Yang, Jennifer A Solski, Ruvini Fernando, Guy A Rouleau, Garth A Nicholson, Ian P Blair. Neurobiol Aging 2012
102
13

ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B).
N Parkinson, P G Ince, M O Smith, R Highley, G Skibinski, P M Andersen, K E Morrison, H S Pall, O Hardiman, J Collinge,[...]. Neurology 2006
283
12

TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis.
Edor Kabashi, Paul N Valdmanis, Patrick Dion, Dan Spiegelman, Brendan J McConkey, Christine Vande Velde, Jean-Pierre Bouchard, Lucette Lacomblez, Ksenia Pochigaeva, Francois Salachas,[...]. Nat Genet 2008
12

RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43.
Jacob R Mann, Amanda M Gleixner, Jocelyn C Mauna, Edward Gomes, Michael R DeChellis-Marks, Patrick G Needham, Katie E Copley, Bryan Hurtle, Bede Portz, Noah J Pyles,[...]. Neuron 2019
150
12

CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia.
Kelly L Williams, Simon Topp, Shu Yang, Bradley Smith, Jennifer A Fifita, Sadaf T Warraich, Katharine Y Zhang, Natalie Farrawell, Caroline Vance, Xun Hu,[...]. Nat Commun 2016
105
12

ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain.
Alexander E Conicella, Gül H Zerze, Jeetain Mittal, Nicolas L Fawzi. Structure 2016
305
12

Pathogenic Ubqln2 gains toxic properties to induce neuron death.
Qinxue Wu, Mujun Liu, Cao Huang, Xionghao Liu, Bo Huang, Niansheng Li, Hongxia Zhou, Xu-Gang Xia. Acta Neuropathol 2015
46
26

Key role of UBQLN2 in pathogenesis of amyotrophic lateral sclerosis and frontotemporal dementia.
Laurence Renaud, Vincent Picher-Martel, Philippe Codron, Jean-Pierre Julien. Acta Neuropathol Commun 2019
29
41

A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement.
Sylvie Bannwarth, Samira Ait-El-Mkadem, Annabelle Chaussenot, Emmanuelle C Genin, Sandra Lacas-Gervais, Konstantina Fragaki, Laetitia Berg-Alonso, Yusuke Kageyama, Valérie Serre, David G Moore,[...]. Brain 2014
256
11

DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4).
Ying-Zhang Chen, Craig L Bennett, Huy M Huynh, Ian P Blair, Imke Puls, Joy Irobi, Ines Dierick, Annette Abel, Marina L Kennerson, Bruce A Rabin,[...]. Am J Hum Genet 2004
550
11

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy.
Serhiy Pankiv, Terje Høyvarde Clausen, Trond Lamark, Andreas Brech, Jack-Ansgar Bruun, Heidi Outzen, Aud Øvervatn, Geir Bjørkøy, Terje Johansen. J Biol Chem 2007
11

Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities.
Fiona M Menzies, Angeleen Fleming, Andrea Caricasole, Carla F Bento, Stephen P Andrews, Avraham Ashkenazi, Jens Füllgrabe, Anne Jackson, Maria Jimenez Sanchez, Cansu Karabiyik,[...]. Neuron 2017
473
11

Mutant UBQLN2P497H in motor neurons leads to ALS-like phenotypes and defective autophagy in rats.
Tianhong Chen, Bo Huang, Xinglong Shi, Limo Gao, Cao Huang. Acta Neuropathol Commun 2018
20
55


SQSTM1 mutations in French patients with frontotemporal dementia or frontotemporal dementia with amyotrophic lateral sclerosis.
Isabelle Le Ber, Agnès Camuzat, Rita Guerreiro, Kawtar Bouya-Ahmed, Jose Bras, Gael Nicolas, Audrey Gabelle, Mira Didic, Anne De Septenville, Stéphanie Millecamps,[...]. JAMA Neurol 2013
121
11

Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly.
Lisa M Sharkey, Nathaniel Safren, Amit S Pithadia, Julia E Gerson, Mark Dulchavsky, Svetlana Fischer, Ronak Patel, Gabrielle Lantis, Naila Ashraf, John H Kim,[...]. Proc Natl Acad Sci U S A 2018
24
45

TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics.
Ian R Mackenzie, Alexandra M Nicholson, Mohona Sarkar, James Messing, Maria D Purice, Cyril Pottier, Kavya Annu, Matt Baker, Ralph B Perkerson, Aishe Kurti,[...]. Neuron 2017
274
10

Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death.
Fatima Gasset-Rosa, Shan Lu, Haiyang Yu, Cong Chen, Ze'ev Melamed, Lin Guo, James Shorter, Sandrine Da Cruz, Don W Cleveland. Neuron 2019
126
10


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.