A citation-based method for searching scientific literature

Han-Xiang Deng, Wenjie Chen, Seong-Tshool Hong, Kym M Boycott, George H Gorrie, Nailah Siddique, Yi Yang, Faisal Fecto, Yong Shi, Hong Zhai, Hujun Jiang, Makito Hirano, Evadnie Rampersaud, Gerard H Jansen, Sandra Donkervoort, Eileen H Bigio, Benjamin R Brooks, Kaouther Ajroud, Robert L Sufit, Jonathan L Haines, Enrico Mugnaini, Margaret A Pericak-Vance, Teepu Siddique. Nature 2011
Times Cited: 824







List of co-cited articles
2332 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Manuela Neumann, Deepak M Sampathu, Linda K Kwong, Adam C Truax, Matthew C Micsenyi, Thomas T Chou, Jennifer Bruce, Theresa Schuck, Murray Grossman, Christopher M Clark,[...]. Science 2006
41

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS.
Mariely DeJesus-Hernandez, Ian R Mackenzie, Bradley F Boeve, Adam L Boxer, Matt Baker, Nicola J Rutherford, Alexandra M Nicholson, NiCole A Finch, Heather Flynn, Jennifer Adamson,[...]. Neuron 2011
40

Mutations of optineurin in amyotrophic lateral sclerosis.
Hirofumi Maruyama, Hiroyuki Morino, Hidefumi Ito, Yuishin Izumi, Hidemasa Kato, Yasuhito Watanabe, Yoshimi Kinoshita, Masaki Kamada, Hiroyuki Nodera, Hidenori Suzuki,[...]. Nature 2010
890
35

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD.
Alan E Renton, Elisa Majounie, Adrian Waite, Javier Simón-Sánchez, Sara Rollinson, J Raphael Gibbs, Jennifer C Schymick, Hannu Laaksovirta, John C van Swieten, Liisa Myllykangas,[...]. Neuron 2011
34

Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis.
T J Kwiatkowski, D A Bosco, A L Leclerc, E Tamrazian, C R Vanderburg, C Russ, A Davis, J Gilchrist, E J Kasarskis, T Munsat,[...]. Science 2009
31

Exome sequencing reveals VCP mutations as a cause of familial ALS.
Janel O Johnson, Jessica Mandrioli, Michael Benatar, Yevgeniya Abramzon, Vivianna M Van Deerlin, John Q Trojanowski, J Raphael Gibbs, Maura Brunetti, Susan Gronka, Joanne Wuu,[...]. Neuron 2010
889
30

Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6.
Caroline Vance, Boris Rogelj, Tibor Hortobágyi, Kurt J De Vos, Agnes Lumi Nishimura, Jemeen Sreedharan, Xun Hu, Bradley Smith, Deborah Ruddy, Paul Wright,[...]. Science 2009
29

SQSTM1 mutations in familial and sporadic amyotrophic lateral sclerosis.
Faisal Fecto, Jianhua Yan, S Pavan Vemula, Erdong Liu, Yi Yang, Wenjie Chen, Jian Guo Zheng, Yong Shi, Nailah Siddique, Hasan Arrat,[...]. Arch Neurol 2011
455
29

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Tetsuaki Arai, Masato Hasegawa, Haruhiko Akiyama, Kenji Ikeda, Takashi Nonaka, Hiroshi Mori, David Mann, Kuniaki Tsuchiya, Mari Yoshida, Yoshio Hashizume,[...]. Biochem Biophys Res Commun 2006
27

UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome.
Roland Hjerpe, John S Bett, Matthew J Keuss, Alexandra Solovyova, Thomas G McWilliams, Clare Johnson, Indrajit Sahu, Joby Varghese, Nicola Wood, Melanie Wightman,[...]. Cell 2016
184
27

Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia.
Axel Freischmidt, Thomas Wieland, Benjamin Richter, Wolfgang Ruf, Veronique Schaeffer, Kathrin Müller, Nicolai Marroquin, Frida Nordin, Annemarie Hübers, Patrick Weydt,[...]. Nat Neurosci 2015
522
25

TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis.
Jemeen Sreedharan, Ian P Blair, Vineeta B Tripathi, Xun Hu, Caroline Vance, Boris Rogelj, Steven Ackerley, Jennifer C Durnall, Kelly L Williams, Emanuele Buratti,[...]. Science 2008
25

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis.
D R Rosen, T Siddique, D Patterson, D A Figlewicz, P Sapp, A Hentati, D Donaldson, J Goto, J P O'Regan, H X Deng. Nature 1993
24

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways.
Elizabeth T Cirulli, Brittany N Lasseigne, Slavé Petrovski, Peter C Sapp, Patrick A Dion, Claire S Leblond, Julien Couthouis, Yi-Fan Lu, Quanli Wang, Brian J Krueger,[...]. Science 2015
628
21

Decoding ALS: from genes to mechanism.
J Paul Taylor, Robert H Brown, Don W Cleveland. Nature 2016
20

Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation.
Elizabeth J Alexander, Amirhossein Ghanbari Niaki, Tao Zhang, Jaya Sarkar, Yang Liu, Raja Sekhar Nirujogi, Akhilesh Pandey, Sua Myong, Jiou Wang. Proc Natl Acad Sci U S A 2018
65
27

Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification.
Mümine Şentürk, Guang Lin, Zhongyuan Zuo, Dongxue Mao, Emma Watson, Antonios G Mikos, Hugo J Bellen. Nat Cell Biol 2019
77
22

Ubiquitin Modulates Liquid-Liquid Phase Separation of UBQLN2 via Disruption of Multivalent Interactions.
Thuy P Dao, Regina-Maria Kolaitis, Hong Joo Kim, Kevin O'Donovan, Brian Martyniak, Erica Colicino, Heidi Hehnly, J Paul Taylor, Carlos A Castañeda. Mol Cell 2018
152
17

Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis.
Shuo-Chien Ling, Magdalini Polymenidou, Don W Cleveland. Neuron 2013
17

TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis.
Edor Kabashi, Paul N Valdmanis, Patrick Dion, Dan Spiegelman, Brendan J McConkey, Christine Vande Velde, Jean-Pierre Bouchard, Lucette Lacomblez, Ksenia Pochigaeva, Francois Salachas,[...]. Nat Genet 2008
15

ALS/FTD mutations in UBQLN2 impede autophagy by reducing autophagosome acidification through loss of function.
Josephine J Wu, Ashley Cai, Jessie E Greenslade, Nicole R Higgins, Cong Fan, Nhat T T Le, Micaela Tatman, Alexandra M Whiteley, Miguel A Prado, Birger V Dieriks,[...]. Proc Natl Acad Sci U S A 2020
31
48

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.
Avinash Patel, Hyun O Lee, Louise Jawerth, Shovamayee Maharana, Marcus Jahnel, Marco Y Hein, Stoyno Stoynov, Julia Mahamid, Shambaditya Saha, Titus M Franzmann,[...]. Cell 2015
14

Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis.
Chi-Hong Wu, Claudia Fallini, Nicola Ticozzi, Pamela J Keagle, Peter C Sapp, Katarzyna Piotrowska, Patrick Lowe, Max Koppers, Diane McKenna-Yasek, Desiree M Baron,[...]. Nature 2012
404
14

Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death.
Chantal Sellier, Maria-Letizia Campanari, Camille Julie Corbier, Angeline Gaucherot, Isabelle Kolb-Cheynel, Mustapha Oulad-Abdelghani, Frank Ruffenach, Adeline Page, Sorana Ciura, Edor Kabashi,[...]. EMBO J 2016
256
14

Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein.
Giles D J Watts, Jill Wymer, Margaret J Kovach, Sarju G Mehta, Steven Mumm, Daniel Darvish, Alan Pestronk, Michael P Whyte, Virginia E Kimonis. Nat Genet 2004
987
14

Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models.
Sami J Barmada, Andrea Serio, Arpana Arjun, Bilada Bilican, Aaron Daub, D Michael Ando, Andrey Tsvetkov, Michael Pleiss, Xingli Li, Daniel Peisach,[...]. Nat Chem Biol 2014
291
14


Protein aggregation in amyotrophic lateral sclerosis.
Anna M Blokhuis, Ewout J N Groen, Max Koppers, Leonard H van den Berg, R Jeroen Pasterkamp. Acta Neuropathol 2013
328
13

ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain.
Alexander E Conicella, Gül H Zerze, Jeetain Mittal, Nicolas L Fawzi. Structure 2016
403
13

Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy.
Cara Rothenberg, Deepa Srinivasan, Leann Mah, Susmita Kaushik, Corrine M Peterhoff, Janet Ugolino, Shengyun Fang, Ana Maria Cuervo, Ralph A Nixon, Mervyn J Monteiro. Hum Mol Genet 2010
175
13

Molecular Mechanisms of TDP-43 Misfolding and Pathology in Amyotrophic Lateral Sclerosis.
Archana Prasad, Vidhya Bharathi, Vishwanath Sivalingam, Amandeep Girdhar, Basant K Patel. Front Mol Neurosci 2019
253
13

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS.
Hong Joo Kim, Nam Chul Kim, Yong-Dong Wang, Emily A Scarborough, Jennifer Moore, Zamia Diaz, Kyle S MacLea, Brian Freibaum, Songqing Li, Amandine Molliex,[...]. Nature 2013
943
12

TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics.
Ian R Mackenzie, Alexandra M Nicholson, Mohona Sarkar, James Messing, Maria D Purice, Cyril Pottier, Kavya Annu, Matt Baker, Ralph B Perkerson, Aishe Kurti,[...]. Neuron 2017
339
12

ALS-Linked Mutations Affect UBQLN2 Oligomerization and Phase Separation in a Position- and Amino Acid-Dependent Manner.
Thuy P Dao, Brian Martyniak, Ashley J Canning, Yongna Lei, Erica G Colicino, Michael S Cosgrove, Heidi Hehnly, Carlos A Castañeda. Structure 2019
43
27

Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly.
Lisa M Sharkey, Nathaniel Safren, Amit S Pithadia, Julia E Gerson, Mark Dulchavsky, Svetlana Fischer, Ronak Patel, Gabrielle Lantis, Naila Ashraf, John H Kim,[...]. Proc Natl Acad Sci U S A 2018
32
37

Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS.
Andrew C Elden, Hyung-Jun Kim, Michael P Hart, Alice S Chen-Plotkin, Brian S Johnson, Xiaodong Fang, Maria Armakola, Felix Geser, Robert Greene, Min Min Lu,[...]. Nature 2010
836
12

UBQLN2/ubiquilin 2 mutation and pathology in familial amyotrophic lateral sclerosis.
Kelly L Williams, Sadaf T Warraich, Shu Yang, Jennifer A Solski, Ruvini Fernando, Guy A Rouleau, Garth A Nicholson, Ian P Blair. Neurobiol Aging 2012
110
12

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.
Aude Nicolas, Kevin P Kenna, Alan E Renton, Nicola Ticozzi, Faraz Faghri, Ruth Chia, Janice A Dominov, Brendan J Kenna, Mike A Nalls, Pamela Keagle,[...]. Neuron 2018
314
12

SQSTM1 mutations in French patients with frontotemporal dementia or frontotemporal dementia with amyotrophic lateral sclerosis.
Isabelle Le Ber, Agnès Camuzat, Rita Guerreiro, Kawtar Bouya-Ahmed, Jose Bras, Gael Nicolas, Audrey Gabelle, Mira Didic, Anne De Septenville, Stéphanie Millecamps,[...]. JAMA Neurol 2013
134
12

CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia.
Kelly L Williams, Simon Topp, Shu Yang, Bradley Smith, Jennifer A Fifita, Sadaf T Warraich, Katharine Y Zhang, Natalie Farrawell, Caroline Vance, Xun Hu,[...]. Nat Commun 2016
128
12

Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons.
Yingxiao Shi, Shaoyu Lin, Kim A Staats, Yichen Li, Wen-Hsuan Chang, Shu-Ting Hung, Eric Hendricks, Gabriel R Linares, Yaoming Wang, Esther Y Son,[...]. Nat Med 2018
280
12

The C9orf72 repeat expansion disrupts nucleocytoplasmic transport.
Ke Zhang, Christopher J Donnelly, Aaron R Haeusler, Jonathan C Grima, James B Machamer, Peter Steinwald, Elizabeth L Daley, Sean J Miller, Kathleen M Cunningham, Svetlana Vidensky,[...]. Nature 2015
621
12

C9orf72 is required for proper macrophage and microglial function in mice.
J G O'Rourke, L Bogdanik, A Yáñez, D Lall, A J Wolf, A K M G Muhammad, R Ho, S Carmona, J P Vit, J Zarrow,[...]. Science 2016
335
11

Mutant UBQLN2P497H in motor neurons leads to ALS-like phenotypes and defective autophagy in rats.
Tianhong Chen, Bo Huang, Xinglong Shi, Limo Gao, Cao Huang. Acta Neuropathol Commun 2018
28
39

Deleterious variants of FIG4, a phosphoinositide phosphatase, in patients with ALS.
Clement Y Chow, John E Landers, Sarah K Bergren, Peter C Sapp, Adrienne E Grant, Julie M Jones, Lesley Everett, Guy M Lenk, Diane M McKenna-Yasek, Lois S Weisman,[...]. Am J Hum Genet 2009
287
11


Eukaryotic stress granules are cleared by autophagy and Cdc48/VCP function.
J Ross Buchan, Regina-Maria Kolaitis, J Paul Taylor, Roy Parker. Cell 2013
458
11

TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD.
Ching-Chieh Chou, Yi Zhang, Mfon E Umoh, Spencer W Vaughan, Ileana Lorenzini, Feilin Liu, Melissa Sayegh, Paul G Donlin-Asp, Yu Han Chen, Duc M Duong,[...]. Nat Neurosci 2018
263
11

Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43.
I-Fang Wang, Bo-Shen Guo, Yu-Chih Liu, Cheng-Chun Wu, Chun-Hung Yang, Kuen-Jer Tsai, Che-Kun James Shen. Proc Natl Acad Sci U S A 2012
278
11

Key role of UBQLN2 in pathogenesis of amyotrophic lateral sclerosis and frontotemporal dementia.
Laurence Renaud, Vincent Picher-Martel, Philippe Codron, Jean-Pierre Julien. Acta Neuropathol Commun 2019
46
23


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.