A citation-based method for searching scientific literature

Cheryl L Strelko, Wenyun Lu, Fay J Dufort, Thomas N Seyfried, Thomas C Chiles, Joshua D Rabinowitz, Mary F Roberts. J Am Chem Soc 2011
Times Cited: 150







List of co-cited articles
934 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production.
Alessandro Michelucci, Thekla Cordes, Jenny Ghelfi, Arnaud Pailot, Norbert Reiling, Oliver Goldmann, Tina Binz, André Wegner, Aravind Tallam, Antonio Rausell,[...]. Proc Natl Acad Sci U S A 2013
426
79

Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.
Vicky Lampropoulou, Alexey Sergushichev, Monika Bambouskova, Sharmila Nair, Emma E Vincent, Ekaterina Loginicheva, Luisa Cervantes-Barragan, Xiucui Ma, Stanley Ching-Cheng Huang, Takla Griss,[...]. Cell Metab 2016
466
72

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Evanna L Mills, Dylan G Ryan, Hiran A Prag, Dina Dikovskaya, Deepthi Menon, Zbigniew Zaslona, Mark P Jedrychowski, Ana S H Costa, Maureen Higgins, Emily Hams,[...]. Nature 2018
466
65

Electrophilic properties of itaconate and derivatives regulate the IκBζ-ATF3 inflammatory axis.
Monika Bambouskova, Laurent Gorvel, Vicky Lampropoulou, Alexey Sergushichev, Ekaterina Loginicheva, Kendall Johnson, Daniel Korenfeld, Mary Elizabeth Mathyer, Hyeryun Kim, Li-Hao Huang,[...]. Nature 2018
207
44

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.
Evanna L Mills, Beth Kelly, Angela Logan, Ana S H Costa, Mukund Varma, Clare E Bryant, Panagiotis Tourlomousis, J Henry M Däbritz, Eyal Gottlieb, Isabel Latorre,[...]. Cell 2016
716
42

Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels.
Thekla Cordes, Martina Wallace, Alessandro Michelucci, Ajit S Divakaruni, Sean C Sapcariu, Carole Sousa, Haruhiko Koseki, Pedro Cabrales, Anne N Murphy, Karsten Hiller,[...]. J Biol Chem 2016
187
42

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.
G M Tannahill, A M Curtis, J Adamik, E M Palsson-McDermott, A F McGettrick, G Goel, C Frezza, N J Bernard, B Kelly, N H Foley,[...]. Nature 2013
41

Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization.
Abhishek K Jha, Stanley Ching-Cheng Huang, Alexey Sergushichev, Vicky Lampropoulou, Yulia Ivanova, Ekaterina Loginicheva, Karina Chmielewski, Kelly M Stewart, Juliet Ashall, Bart Everts,[...]. Immunity 2015
759
34

Itaconic Acid: The Surprising Role of an Industrial Compound as a Mammalian Antimicrobial Metabolite.
Thekla Cordes, Alessandro Michelucci, Karsten Hiller. Annu Rev Nutr 2015
84
33

Itaconate: the poster child of metabolic reprogramming in macrophage function.
Luke A J O'Neill, Maxim N Artyomov. Nat Rev Immunol 2019
118
28


Bacterial itaconate degradation promotes pathogenicity.
Jahminy Sasikaran, Michał Ziemski, Piotr K Zadora, Angela Fleig, Ivan A Berg. Nat Chem Biol 2014
87
28

(1)H NMR-based metabolomic profiling in mice infected with Mycobacterium tuberculosis.
Ji-Hyun Shin, Ji-Young Yang, Bo-Young Jeon, Yoo Jeong Yoon, Sang-Nae Cho, Yeon-Ho Kang, Do Hyun Ryu, Geum-Sook Hwang. J Proteome Res 2011
137
24

IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid.
Jan Naujoks, Christoph Tabeling, Brian D Dill, Christine Hoffmann, Andrew S Brown, Mareike Kunze, Stefan Kempa, Andrea Peter, Hans-Joachim Mollenkopf, Anca Dorhoi,[...]. PLoS Pathog 2016
117
23

Irg1 expression in myeloid cells prevents immunopathology during M. tuberculosis infection.
Sharmila Nair, Jeremy P Huynh, Vicky Lampropoulou, Ekaterina Loginicheva, Ekaterina Esaulova, Anshu P Gounder, Adrianus C M Boon, Elizabeth A Schwarzkopf, Tara R Bradstreet, Brian T Edelson,[...]. J Exp Med 2018
76
28

A guide to immunometabolism for immunologists.
Luke A J O'Neill, Rigel J Kishton, Jeff Rathmell. Nat Rev Immunol 2016
21

Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors.
Jonathan M Weiss, Luke C Davies, Megan Karwan, Lilia Ileva, Michelle K Ozaki, Robert Ys Cheng, Lisa A Ridnour, Christina M Annunziata, David A Wink, Daniel W McVicar. J Clin Invest 2018
73
28

α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming.
Pu-Ste Liu, Haiping Wang, Xiaoyun Li, Tung Chao, Tony Teav, Stefan Christen, Giusy Di Conza, Wan-Chen Cheng, Chih-Hung Chou, Magdalena Vavakova,[...]. Nat Immunol 2017
287
20

Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage.
Beáta Németh, Judit Doczi, Dániel Csete, Gergely Kacso, Dora Ravasz, Daniel Adams, Gergely Kiss, Adam M Nagy, Gergo Horvath, Laszlo Tretter,[...]. FASEB J 2016
68
27

Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation.
Divya Vats, Lata Mukundan, Justin I Odegaard, Lina Zhang, Kristi L Smith, Christine R Morel, Roger A Wagner, David R Greaves, Peter J Murray, Ajay Chawla. Cell Metab 2006
788
19

The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons.
Brian P Daniels, Sigal B Kofman, Julian R Smith, Geoffrey T Norris, Annelise G Snyder, Joseph P Kolb, Xia Gao, Jason W Locasale, Jennifer Martinez, Michael Gale,[...]. Immunity 2019
83
22

The Human Knockout Gene CLYBL Connects Itaconate to Vitamin B12.
Hongying Shen, Gregory C Campanello, Daniel Flicker, Zenon Grabarek, Junchi Hu, Cheng Luo, Ruma Banerjee, Vamsi K Mootha. Cell 2017
52
34

Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages.
Eva M Palsson-McDermott, Anne M Curtis, Gautam Goel, Mario A R Lauterbach, Frederick J Sheedy, Laura E Gleeson, Mirjam W M van den Bosch, Susan R Quinn, Raquel Domingo-Fernandez, Daniel G W Johnston,[...]. Cell Metab 2015
469
17

The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity.
Jorge Domínguez-Andrés, Boris Novakovic, Yang Li, Brendon P Scicluna, Mark S Gresnigt, Rob J W Arts, Marije Oosting, Simone J C F M Moorlag, Laszlo A Groh, Jelle Zwaag,[...]. Cell Metab 2019
105
17

The mitochondrial citrate carrier: a new player in inflammation.
Vittoria Infantino, Paolo Convertini, Liana Cucci, Maria Antonietta Panaro, Maria Antonietta Di Noia, Rosa Calvello, Ferdinando Palmieri, Vito Iacobazzi. Biochem J 2011
213
16

Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells.
Bart Everts, Eyal Amiel, Gerritje J W van der Windt, Tori C Freitas, Robert Chott, Kevin E Yarasheski, Erika L Pearce, Edward J Pearce. Blood 2012
328
16

Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages.
Jan Van den Bossche, Jeroen Baardman, Natasja A Otto, Saskia van der Velden, Annette E Neele, Susan M van den Berg, Rosario Luque-Martin, Hung-Jen Chen, Marieke C S Boshuizen, Mohamed Ahmed,[...]. Cell Rep 2016
276
16

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.
Edward T Chouchani, Victoria R Pell, Edoardo Gaude, Dunja Aksentijević, Stephanie Y Sundier, Ellen L Robb, Angela Logan, Sergiy M Nadtochiy, Emily N J Ord, Anthony C Smith,[...]. Nature 2014
15

GPR91 senses extracellular succinate released from inflammatory macrophages and exacerbates rheumatoid arthritis.
Amanda Littlewood-Evans, Sophie Sarret, Verena Apfel, Perrine Loesle, Janet Dawson, Juan Zhang, Alban Muller, Bruno Tigani, Rainer Kneuer, Saijel Patel,[...]. J Exp Med 2016
188
15

Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation.
Stanley Ching-Cheng Huang, Amber M Smith, Bart Everts, Marco Colonna, Erika L Pearce, Joel D Schilling, Edward J Pearce. Immunity 2016
251
15

Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages.
Stanley Ching-Cheng Huang, Bart Everts, Yulia Ivanova, David O'Sullivan, Marcia Nascimento, Amber M Smith, Wandy Beatty, Latisha Love-Gregory, Wing Y Lam, Christina M O'Neill,[...]. Nat Immunol 2014
550
15

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.
Oscar R Colegio, Ngoc-Quynh Chu, Alison L Szabo, Thach Chu, Anne Marie Rhebergen, Vikram Jairam, Nika Cyrus, Carolyn E Brokowski, Stephanie C Eisenbarth, Gillian M Phillips,[...]. Nature 2014
15

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase.
Mary A Selak, Sean M Armour, Elaine D MacKenzie, Houda Boulahbel, David G Watson, Kyle D Mansfield, Yi Pan, M Celeste Simon, Craig B Thompson, Eyal Gottlieb. Cancer Cell 2005
14

Dimethyl Itaconate Is Not Metabolized into Itaconate Intracellularly.
Mahmoud ElAzzouny, Christopher T M B Tom, Charles R Evans, Lori L Olson, Mary J Tanga, Katherine A Gallagher, Brent R Martin, Charles F Burant. J Biol Chem 2017
35
40

Substrate fate in activated macrophages: a comparison between innate, classic, and alternative activation.
Juan-Carlos Rodríguez-Prados, Paqui G Través, Jimena Cuenca, Daniel Rico, Julián Aragonés, Paloma Martín-Sanz, Marta Cascante, Lisardo Boscá. J Immunol 2010
546
14


S-glycosylation-based cysteine profiling reveals regulation of glycolysis by itaconate.
Wei Qin, Ke Qin, Yanling Zhang, Wentong Jia, Ying Chen, Bo Cheng, Linghang Peng, Nan Chen, Yuan Liu, Wen Zhou,[...]. Nat Chem Biol 2019
48
29

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.
A Phillip West, Igor E Brodsky, Christoph Rahner, Dong Kyun Woo, Hediye Erdjument-Bromage, Paul Tempst, Matthew C Walsh, Yongwon Choi, Gerald S Shadel, Sankar Ghosh. Nature 2011
863
13

Immunometabolism governs dendritic cell and macrophage function.
Luke A J O'Neill, Edward J Pearce. J Exp Med 2016
705
13

The sedoheptulose kinase CARKL directs macrophage polarization through control of glucose metabolism.
Arvand Haschemi, Paul Kosma, Lars Gille, Charles R Evans, Charles F Burant, Philipp Starkl, Bernhard Knapp, Robert Haas, Johannes A Schmid, Christoph Jandl,[...]. Cell Metab 2012
323
13

Immunoresponsive gene 1 augments bactericidal activity of macrophage-lineage cells by regulating β-oxidation-dependent mitochondrial ROS production.
Christopher J Hall, Rachel H Boyle, Jonathan W Astin, Maria Vega Flores, Stefan H Oehlers, Leslie E Sanderson, Felix Ellett, Graham J Lieschke, Kathryn E Crosier, Philip S Crosier. Cell Metab 2013
129
13

Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription.
Eri H Kobayashi, Takafumi Suzuki, Ryo Funayama, Takeshi Nagashima, Makiko Hayashi, Hiroki Sekine, Nobuyuki Tanaka, Takashi Moriguchi, Hozumi Motohashi, Keiko Nakayama,[...]. Nat Commun 2016
589
13

Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation.
Connie M Krawczyk, Thomas Holowka, Jie Sun, Julianna Blagih, Eyal Amiel, Ralph J DeBerardinis, Justin R Cross, Euihye Jung, Craig B Thompson, Russell G Jones,[...]. Blood 2010
661
13

Comparative evaluation of itaconate and its derivatives reveals divergent inflammasome and type I interferon regulation in macrophages.
Amanda Swain, Monika Bambouskova, Hyeryun Kim, Prabhakar Sairam Andhey, Dustin Duncan, Karine Auclair, Victor Chubukov, Donald M Simons, Thomas P Roddy, Kelly M Stewart,[...]. Nat Metab 2020
38
34

Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity.
Rob J W Arts, Boris Novakovic, Rob Ter Horst, Agostinho Carvalho, Siroon Bekkering, Ekta Lachmandas, Fernando Rodrigues, Ricardo Silvestre, Shih-Chin Cheng, Shuang-Yin Wang,[...]. Cell Metab 2016
313
12

ATP-citrate lyase is essential for macrophage inflammatory response.
Vittoria Infantino, Vito Iacobazzi, Ferdinando Palmieri, Alessio Menga. Biochem Biophys Res Commun 2013
125
12

TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation.
Bart Everts, Eyal Amiel, Stanley Ching-Cheng Huang, Amber M Smith, Chih-Hao Chang, Wing Y Lam, Veronika Redmann, Tori C Freitas, Julianna Blagih, Gerritje J W van der Windt,[...]. Nat Immunol 2014
540
12

Mechanism of action of isocitrate lyase from Pseudomonas indigofera.
J O Williams, T E Roche, B A McFadden. Biochemistry 1971
68
17

Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity.
Michael D Kornberg, Pavan Bhargava, Paul M Kim, Vasanta Putluri, Adele M Snowman, Nagireddy Putluri, Peter A Calabresi, Solomon H Snyder. Science 2018
215
12

Immune responsive gene 1 (IRG1) promotes endotoxin tolerance by increasing A20 expression in macrophages through reactive oxygen species.
Yingke Li, Peng Zhang, Chengcai Wang, Chaofeng Han, Jun Meng, Xingguang Liu, Sheng Xu, Nan Li, Qingqing Wang, Xueyin Shi,[...]. J Biol Chem 2013
90
12


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.