Nilesh K Sharma, Aurelio Reyes, Paula Green, Matthieu J Caron, Marcelo G Bonini, Donna M Gordon, Ian J Holt, Janine Hertzog Santos. Nucleic Acids Res 2012
Times Cited: 101
Times Cited: 101
Times Cited
Times Co-cited
Similarity
Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage.
Judith Haendeler, Stefan Dröse, Nicole Büchner, Sascha Jakob, Joachim Altschmied, Christine Goy, Ioakim Spyridopoulos, Andreas M Zeiher, Ulrich Brandt, Stefanie Dimmeler. Arterioscler Thromb Vasc Biol 2009
Judith Haendeler, Stefan Dröse, Nicole Büchner, Sascha Jakob, Joachim Altschmied, Christine Goy, Ioakim Spyridopoulos, Andreas M Zeiher, Ulrich Brandt, Stefanie Dimmeler. Arterioscler Thromb Vasc Biol 2009
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Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress.
Shaheda Ahmed, João F Passos, Matthew J Birket, Tina Beckmann, Sebastian Brings, Heiko Peters, Mark A Birch-Machin, Thomas von Zglinicki, Gabriele Saretzki. J Cell Sci 2008
Shaheda Ahmed, João F Passos, Matthew J Birket, Tina Beckmann, Sebastian Brings, Heiko Peters, Mark A Birch-Machin, Thomas von Zglinicki, Gabriele Saretzki. J Cell Sci 2008
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Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage.
Janine Hertzog Santos, Joel N Meyer, Milan Skorvaga, Lois A Annab, Bennett Van Houten. Aging Cell 2004
Janine Hertzog Santos, Joel N Meyer, Milan Skorvaga, Lois A Annab, Bennett Van Houten. Aging Cell 2004
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Hydrogen peroxide triggers nuclear export of telomerase reverse transcriptase via Src kinase family-dependent phosphorylation of tyrosine 707.
Judith Haendeler, Jörg Hoffmann, Ralf P Brandes, Andreas M Zeiher, Stefanie Dimmeler. Mol Cell Biol 2003
Judith Haendeler, Jörg Hoffmann, Ralf P Brandes, Andreas M Zeiher, Stefanie Dimmeler. Mol Cell Biol 2003
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An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA.
Yoshiko Maida, Mami Yasukawa, Miho Furuuchi, Timo Lassmann, Richard Possemato, Naoko Okamoto, Vivi Kasim, Yoshihide Hayashizaki, William C Hahn, Kenkichi Masutomi. Nature 2009
Yoshiko Maida, Mami Yasukawa, Miho Furuuchi, Timo Lassmann, Richard Possemato, Naoko Okamoto, Vivi Kasim, Yoshihide Hayashizaki, William C Hahn, Kenkichi Masutomi. Nature 2009
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hTERT overexpression alleviates intracellular ROS production, improves mitochondrial function, and inhibits ROS-mediated apoptosis in cancer cells.
Inthrani R Indran, Manoor P Hande, Shazib Pervaiz. Cancer Res 2011
Inthrani R Indran, Manoor P Hande, Shazib Pervaiz. Cancer Res 2011
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Mitochondrial localization of telomerase as a determinant for hydrogen peroxide-induced mitochondrial DNA damage and apoptosis.
Janine Hertzog Santos, Joel N Meyer, Bennett Van Houten. Hum Mol Genet 2006
Janine Hertzog Santos, Joel N Meyer, Bennett Van Houten. Hum Mol Genet 2006
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Telomere dysfunction induces metabolic and mitochondrial compromise.
Ergün Sahin, Simona Colla, Marc Liesa, Javid Moslehi, Florian L Müller, Mira Guo, Marcus Cooper, Darrell Kotton, Attila J Fabian, Carl Walkey,[...]. Nature 2011
Ergün Sahin, Simona Colla, Marc Liesa, Javid Moslehi, Florian L Müller, Mira Guo, Marcus Cooper, Darrell Kotton, Attila J Fabian, Carl Walkey,[...]. Nature 2011
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Mitochondrial telomerase protects cancer cells from nuclear DNA damage and apoptosis.
Chatchawan Singhapol, Deepali Pal, Rafal Czapiewski, Mahendar Porika, Glyn Nelson, Gabriele C Saretzki. PLoS One 2013
Chatchawan Singhapol, Deepali Pal, Rafal Czapiewski, Mahendar Porika, Glyn Nelson, Gabriele C Saretzki. PLoS One 2013
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A mutant telomerase defective in nuclear-cytoplasmic shuttling fails to immortalize cells and is associated with mitochondrial dysfunction.
Olga A Kovalenko, Matthieu J Caron, Perihan Ulema, Carolina Medrano, Andrew P Thomas, Masayuki Kimura, Marcelo G Bonini, Utz Herbig, Janine H Santos. Aging Cell 2010
Olga A Kovalenko, Matthieu J Caron, Perihan Ulema, Carolina Medrano, Andrew P Thomas, Masayuki Kimura, Marcelo G Bonini, Utz Herbig, Janine H Santos. Aging Cell 2010
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Telomerase modulates Wnt signalling by association with target gene chromatin.
Jae-Il Park, Andrew S Venteicher, Ji Yeon Hong, Jinkuk Choi, Sohee Jun, Marina Shkreli, Woody Chang, Zhaojing Meng, Peggie Cheung, Hong Ji,[...]. Nature 2009
Jae-Il Park, Andrew S Venteicher, Ji Yeon Hong, Jinkuk Choi, Sohee Jun, Marina Shkreli, Woody Chang, Zhaojing Meng, Peggie Cheung, Hong Ji,[...]. Nature 2009
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TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program.
Jinkuk Choi, Lucinda K Southworth, Kavita Y Sarin, Andrew S Venteicher, Wenxiu Ma, Woody Chang, Peggie Cheung, Sohee Jun, Maja K Artandi, Naman Shah,[...]. PLoS Genet 2008
Jinkuk Choi, Lucinda K Southworth, Kavita Y Sarin, Andrew S Venteicher, Wenxiu Ma, Woody Chang, Peggie Cheung, Sohee Jun, Maja K Artandi, Naman Shah,[...]. PLoS Genet 2008
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Telomerase modulates expression of growth-controlling genes and enhances cell proliferation.
Laura L Smith, Hilary A Coller, James M Roberts. Nat Cell Biol 2003
Laura L Smith, Hilary A Coller, James M Roberts. Nat Cell Biol 2003
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The telomerase reverse transcriptase regulates chromatin state and DNA damage responses.
Kenkichi Masutomi, Richard Possemato, Judy M Y Wong, Jennifer L Currier, Zuzana Tothova, Judith B Manola, Shridar Ganesan, Peter M Lansdorp, Kathleen Collins, William C Hahn. Proc Natl Acad Sci U S A 2005
Kenkichi Masutomi, Richard Possemato, Judy M Y Wong, Jennifer L Currier, Zuzana Tothova, Judith B Manola, Shridar Ganesan, Peter M Lansdorp, Kathleen Collins, William C Hahn. Proc Natl Acad Sci U S A 2005
19
Antioxidants inhibit nuclear export of telomerase reverse transcriptase and delay replicative senescence of endothelial cells.
Judith Haendeler, Jörg Hoffmann, J Florian Diehl, Mariuca Vasa, Ioakim Spyridopoulos, Andreas M Zeiher, Stefanie Dimmeler. Circ Res 2004
Judith Haendeler, Jörg Hoffmann, J Florian Diehl, Mariuca Vasa, Ioakim Spyridopoulos, Andreas M Zeiher, Stefanie Dimmeler. Circ Res 2004
17
Conditional telomerase induction causes proliferation of hair follicle stem cells.
Kavita Y Sarin, Peggie Cheung, Daniel Gilison, Eunice Lee, Ruth I Tennen, Estee Wang, Maja K Artandi, Anthony E Oro, Steven E Artandi. Nature 2005
Kavita Y Sarin, Peggie Cheung, Daniel Gilison, Eunice Lee, Ruth I Tennen, Estee Wang, Maja K Artandi, Anthony E Oro, Steven E Artandi. Nature 2005
16
Specific association of human telomerase activity with immortal cells and cancer.
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
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Extension of life-span by introduction of telomerase into normal human cells.
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
16
Downregulation of mitochondrial telomerase reverse transcriptase induced by H2O2 is Src kinase dependent.
Nicole Büchner, Tim-Christian Zschauer, Margarete Lukosz, Joachim Altschmied, Judith Haendeler. Exp Gerontol 2010
Nicole Büchner, Tim-Christian Zschauer, Margarete Lukosz, Joachim Altschmied, Judith Haendeler. Exp Gerontol 2010
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Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins.
Paula Martínez, María A Blasco. Nat Rev Cancer 2011
Paula Martínez, María A Blasco. Nat Rev Cancer 2011
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Nuclear import of hTERT requires a bipartite nuclear localization signal and Akt-mediated phosphorylation.
Jeeyun Chung, Prabhat Khadka, In Kwon Chung. J Cell Sci 2012
Jeeyun Chung, Prabhat Khadka, In Kwon Chung. J Cell Sci 2012
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Shelterin: the protein complex that shapes and safeguards human telomeres.
Titia de Lange. Genes Dev 2005
Titia de Lange. Genes Dev 2005
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Telomere shortening and tumor formation by mouse cells lacking telomerase RNA.
M A Blasco, H W Lee, M P Hande, E Samper, P M Lansdorp, R A DePinho, C W Greider. Cell 1997
M A Blasco, H W Lee, M P Hande, E Samper, P M Lansdorp, R A DePinho, C W Greider. Cell 1997
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Telomere-independent functions of telomerase in nuclei, cytoplasm, and mitochondria.
Ilaria Chiodi, Chiara Mondello. Front Oncol 2012
Ilaria Chiodi, Chiara Mondello. Front Oncol 2012
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Extra-telomeric functions of human telomerase: cancer, mitochondria and oxidative stress.
G Saretzki. Curr Pharm Des 2014
G Saretzki. Curr Pharm Des 2014
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The role of telomerase protein TERT in Alzheimer's disease and in tau-related pathology in vitro.
Alison Spilsbury, Satomi Miwa, Johannes Attems, Gabriele Saretzki. J Neurosci 2015
Alison Spilsbury, Satomi Miwa, Johannes Attems, Gabriele Saretzki. J Neurosci 2015
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Telomerase directly regulates NF-κB-dependent transcription.
Arkasubhra Ghosh, Gaye Saginc, Shi Chi Leow, Ekta Khattar, Eun Myong Shin, Ting Dong Yan, Marc Wong, Zhizhuo Zhang, Guoliang Li, Wing-Kin Sung,[...]. Nat Cell Biol 2012
Arkasubhra Ghosh, Gaye Saginc, Shi Chi Leow, Ekta Khattar, Eun Myong Shin, Ting Dong Yan, Marc Wong, Zhizhuo Zhang, Guoliang Li, Wing-Kin Sung,[...]. Nat Cell Biol 2012
13
Cytoplasmic TERT Associates to RNA Granules in Fully Mature Neurons: Role in the Translational Control of the Cell Cycle Inhibitor p15INK4B.
Francesca Iannilli, Francesca Zalfa, Annette Gartner, Claudia Bagni, Carlos G Dotti. PLoS One 2013
Francesca Iannilli, Francesca Zalfa, Annette Gartner, Claudia Bagni, Carlos G Dotti. PLoS One 2013
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Novel telomerase-increasing compound in mouse brain delays the onset of amyotrophic lateral sclerosis.
Erez Eitan, Ailon Tichon, Aviv Gazit, Daniel Gitler, Shimon Slavin, Esther Priel. EMBO Mol Med 2012
Erez Eitan, Ailon Tichon, Aviv Gazit, Daniel Gitler, Shimon Slavin, Esther Priel. EMBO Mol Med 2012
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12
The major reverse transcriptase-incompetent splice variant of the human telomerase protein inhibits telomerase activity but protects from apoptosis.
Imke Listerman, Jie Sun, Francesca S Gazzaniga, Jason L Lukas, Elizabeth H Blackburn. Cancer Res 2013
Imke Listerman, Jie Sun, Francesca S Gazzaniga, Jason L Lukas, Elizabeth H Blackburn. Cancer Res 2013
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Critical Role for Telomerase in the Mechanism of Flow-Mediated Dilation in the Human Microcirculation.
Andreas M Beyer, Julie K Freed, Matthew J Durand, Michael Riedel, Karima Ait-Aissa, Paula Green, Joseph C Hockenberry, R Garret Morgan, Anthony J Donato, Refael Peleg,[...]. Circ Res 2016
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TERT promotes cellular and organismal survival independently of telomerase activity.
J Lee, Y H Sung, C Cheong, Y S Choi, H K Jeon, W Sun, W C Hahn, F Ishikawa, H-W Lee. Oncogene 2008
J Lee, Y H Sung, C Cheong, Y S Choi, H K Jeon, W Sun, W C Hahn, F Ishikawa, H-W Lee. Oncogene 2008
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Nuclear protein tyrosine phosphatase Shp-2 is one important negative regulator of nuclear export of telomerase reverse transcriptase.
Sascha Jakob, Peter Schroeder, Margarete Lukosz, Nicole Büchner, Ioakim Spyridopoulos, Joachim Altschmied, Judith Haendeler. J Biol Chem 2008
Sascha Jakob, Peter Schroeder, Margarete Lukosz, Nicole Büchner, Ioakim Spyridopoulos, Joachim Altschmied, Judith Haendeler. J Biol Chem 2008
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Identification of a specific telomere terminal transferase activity in Tetrahymena extracts.
C W Greider, E H Blackburn. Cell 1985
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Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells.
Katrin Hoffmeyer, Angelo Raggioli, Stefan Rudloff, Roman Anton, Andreas Hierholzer, Ignacio Del Valle, Kerstin Hein, Riana Vogt, Rolf Kemler. Science 2012
Katrin Hoffmeyer, Angelo Raggioli, Stefan Rudloff, Roman Anton, Andreas Hierholzer, Ignacio Del Valle, Kerstin Hein, Riana Vogt, Rolf Kemler. Science 2012
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The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
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The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence.
Bruno Bernardes de Jesus, Kerstin Schneeberger, Elsa Vera, Agueda Tejera, Calvin B Harley, Maria A Blasco. Aging Cell 2011
Bruno Bernardes de Jesus, Kerstin Schneeberger, Elsa Vera, Agueda Tejera, Calvin B Harley, Maria A Blasco. Aging Cell 2011
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Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice.
Mariela Jaskelioff, Florian L Muller, Ji-Hye Paik, Emily Thomas, Shan Jiang, Andrew C Adams, Ergun Sahin, Maria Kost-Alimova, Alexei Protopopov, Juan Cadiñanos,[...]. Nature 2011
Mariela Jaskelioff, Florian L Muller, Ji-Hye Paik, Emily Thomas, Shan Jiang, Andrew C Adams, Ergun Sahin, Maria Kost-Alimova, Alexei Protopopov, Juan Cadiñanos,[...]. Nature 2011
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Involvement of 14-3-3 proteins in nuclear localization of telomerase.
H Seimiya, H Sawada, Y Muramatsu, M Shimizu, K Ohko, K Yamane, T Tsuruo. EMBO J 2000
H Seimiya, H Sawada, Y Muramatsu, M Shimizu, K Ohko, K Yamane, T Tsuruo. EMBO J 2000
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Protein composition of catalytically active human telomerase from immortal cells.
Scott B Cohen, Mark E Graham, George O Lovrecz, Nicolai Bache, Phillip J Robinson, Roger R Reddel. Science 2007
Scott B Cohen, Mark E Graham, George O Lovrecz, Nicolai Bache, Phillip J Robinson, Roger R Reddel. Science 2007
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Separation of telomerase functions by reverse genetics.
Shibani Mukherjee, Eduardo J Firpo, Yang Wang, James M Roberts. Proc Natl Acad Sci U S A 2011
Shibani Mukherjee, Eduardo J Firpo, Yang Wang, James M Roberts. Proc Natl Acad Sci U S A 2011
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The catalytic subunit of telomerase is expressed in developing brain neurons and serves a cell survival-promoting function.
W Fu, M Killen, C Culmsee, S Dhar, T K Pandita, M P Mattson. J Mol Neurosci 2000
W Fu, M Killen, C Culmsee, S Dhar, T K Pandita, M P Mattson. J Mol Neurosci 2000
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Phenotypes in mTERT⁺/⁻ and mTERT⁻/⁻ mice are due to short telomeres, not telomere-independent functions of telomerase reverse transcriptase.
Margaret A Strong, Sofia L Vidal-Cardenas, Baktiar Karim, Huimin Yu, Nini Guo, Carol W Greider. Mol Cell Biol 2011
Margaret A Strong, Sofia L Vidal-Cardenas, Baktiar Karim, Huimin Yu, Nini Guo, Carol W Greider. Mol Cell Biol 2011
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Telomeres shorten during ageing of human fibroblasts.
C B Harley, A B Futcher, C W Greider. Nature 1990
C B Harley, A B Futcher, C W Greider. Nature 1990
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