Jiri Lukas, Claudia Lukas, Jiri Bartek. Nat Cell Biol 2011
Times Cited: 463
Times Cited: 463
Times Cited
Times Co-cited
Similarity
The DNA-damage response in human biology and disease.
Stephen P Jackson, Jiri Bartek. Nature 2009
Stephen P Jackson, Jiri Bartek. Nature 2009
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The DNA damage response: making it safe to play with knives.
Alberto Ciccia, Stephen J Elledge. Mol Cell 2010
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Double-strand break repair: 53BP1 comes into focus.
Stephanie Panier, Simon J Boulton. Nat Rev Mol Cell Biol 2014
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RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins.
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RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling.
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53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks.
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Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications.
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Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks.
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ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks.
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53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark.
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Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination.
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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139.
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Regulation of DNA double-strand break repair by ubiquitin and ubiquitin-like modifiers.
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The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage.
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Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair.
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Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining.
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The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1 through Direct H4K20me Binding and H2AK15 Acetylation.
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RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly.
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10
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks.
Manuel Stucki, Julie A Clapperton, Duaa Mohammad, Michael B Yaffe, Stephen J Smerdon, Stephen P Jackson. Cell 2005
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SETD2-dependent histone H3K36 trimethylation is required for homologous recombination repair and genome stability.
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Regulation of DNA damage responses by ubiquitin and SUMO.
Stephen P Jackson, Daniel Durocher. Mol Cell 2013
Stephen P Jackson, Daniel Durocher. Mol Cell 2013
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A macrohistone variant links dynamic chromatin compaction to BRCA1-dependent genome maintenance.
Simran Khurana, Michael J Kruhlak, Jeongkyu Kim, Andy D Tran, Jinping Liu, Katherine Nyswaner, Lei Shi, Parthav Jailwala, Myong-Hee Sung, Ofir Hakim,[...]. Cell Rep 2014
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8
MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites.
Huadong Pei, Lindsey Zhang, Kuntian Luo, Yuxin Qin, Marta Chesi, Frances Fei, P Leif Bergsagel, Liewei Wang, Zhongsheng You, Zhenkun Lou. Nature 2011
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Histone H4 deacetylation facilitates 53BP1 DNA damage signaling and double-strand break repair.
Kuei-Yang Hsiao, Craig A Mizzen. J Mol Cell Biol 2013
Kuei-Yang Hsiao, Craig A Mizzen. J Mol Cell Biol 2013
8
A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice.
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Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase.
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RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins.
Niels Mailand, Simon Bekker-Jensen, Helene Faustrup, Fredrik Melander, Jiri Bartek, Claudia Lukas, Jiri Lukas. Cell 2007
Niels Mailand, Simon Bekker-Jensen, Helene Faustrup, Fredrik Melander, Jiri Bartek, Claudia Lukas, Jiri Lukas. Cell 2007
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BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair.
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53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers.
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Prime, repair, restore: the active role of chromatin in the DNA damage response.
Gaston Soria, Sophie E Polo, Geneviève Almouzni. Mol Cell 2012
Gaston Soria, Sophie E Polo, Geneviève Almouzni. Mol Cell 2012
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High-resolution profiling of gammaH2AX around DNA double strand breaks in the mammalian genome.
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Histone H2A.Z controls a critical chromatin remodeling step required for DNA double-strand break repair.
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Histone demethylase KDM5A regulates the ZMYND8-NuRD chromatin remodeler to promote DNA repair.
Fade Gong, Thomas Clouaire, Marion Aguirrebengoa, Gaëlle Legube, Kyle M Miller. J Cell Biol 2017
Fade Gong, Thomas Clouaire, Marion Aguirrebengoa, Gaëlle Legube, Kyle M Miller. J Cell Biol 2017
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ATR: an essential regulator of genome integrity.
Karlene A Cimprich, David Cortez. Nat Rev Mol Cell Biol 2008
Karlene A Cimprich, David Cortez. Nat Rev Mol Cell Biol 2008
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p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks.
L B Schultz, N H Chehab, A Malikzay, T D Halazonetis. J Cell Biol 2000
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Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks.
Arkady Celeste, Oscar Fernandez-Capetillo, Michael J Kruhlak, Duane R Pilch, David W Staudt, Alicia Lee, Robert F Bonner, William M Bonner, André Nussenzweig. Nat Cell Biol 2003
Arkady Celeste, Oscar Fernandez-Capetillo, Michael J Kruhlak, Duane R Pilch, David W Staudt, Alicia Lee, Robert F Bonner, William M Bonner, André Nussenzweig. Nat Cell Biol 2003
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RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.
J Ross Chapman, Patricia Barral, Jean-Baptiste Vannier, Valérie Borel, Martin Steger, Antonia Tomas-Loba, Alessandro A Sartori, Ian R Adams, Facundo D Batista, Simon J Boulton. Mol Cell 2013
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Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1.
Simon Bekker-Jensen, Claudia Lukas, Fredrik Melander, Jiri Bartek, Jiri Lukas. J Cell Biol 2005
Simon Bekker-Jensen, Claudia Lukas, Fredrik Melander, Jiri Bartek, Jiri Lukas. J Cell Biol 2005
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ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response.
Andrew N Blackford, Stephen P Jackson. Mol Cell 2017
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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.
Helen E Bryant, Niklas Schultz, Huw D Thomas, Kayan M Parker, Dan Flower, Elena Lopez, Suzanne Kyle, Mark Meuth, Nicola J Curtin, Thomas Helleday. Nature 2005
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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
Hannah Farmer, Nuala McCabe, Christopher J Lord, Andrew N J Tutt, Damian A Johnson, Tobias B Richardson, Manuela Santarosa, Krystyna J Dillon, Ian Hickson, Charlotte Knights,[...]. Nature 2005
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