A citation-based method for searching scientific literature

Vrajesh Karkhanis, Yu-Jie Hu, Robert A Baiocchi, Anthony N Imbalzano, Saïd Sif. Trends Biochem Sci 2011
Times Cited: 166







List of co-cited articles
617 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


The PRMT5 arginine methyltransferase: many roles in development, cancer and beyond.
Nicole Stopa, Jocelyn E Krebs, David Shechter. Cell Mol Life Sci 2015
218
45

A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models.
Elayne Chan-Penebre, Kristy G Kuplast, Christina R Majer, P Ann Boriack-Sjodin, Tim J Wigle, L Danielle Johnston, Nathalie Rioux, Michael J Munchhof, Lei Jin, Suzanne L Jacques,[...]. Nat Chem Biol 2015
286
44

Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes.
Sharmistha Pal, Sheethal N Vishwanath, Hediye Erdjument-Bromage, Paul Tempst, Saïd Sif. Mol Cell Biol 2004
430
42

Protein arginine methyltransferases and cancer.
Yanzhong Yang, Mark T Bedford. Nat Rev Cancer 2013
594
40

Protein arginine methylation in mammals: who, what, and why.
Mark T Bedford, Steven G Clarke. Mol Cell 2009
33

Arginine Methylation: The Coming of Age.
Roméo S Blanc, Stéphane Richard. Mol Cell 2017
389
31

Arginine methylation regulates the p53 response.
Martin Jansson, Stephen T Durant, Er-Chieh Cho, Sharon Sheahan, Mariola Edelmann, Benedikt Kessler, Nicholas B La Thangue. Nat Cell Biol 2008
310
30

Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency.
Wee-Wei Tee, Mercedes Pardo, Thorold W Theunissen, Lu Yu, Jyoti S Choudhary, Petra Hajkova, M Azim Surani. Genes Dev 2010
220
28

Low levels of miR-92b/96 induce PRMT5 translation and H3R8/H4R3 methylation in mantle cell lymphoma.
Sharmistha Pal, Robert A Baiocchi, John C Byrd, Michael R Grever, Samson T Jacob, Saïd Sif. EMBO J 2007
197
27


Crystal structure of the human PRMT5:MEP50 complex.
Stephen Antonysamy, Zahid Bonday, Robert M Campbell, Brandon Doyle, Zhanna Druzina, Tarun Gheyi, Bomie Han, Louis N Jungheim, Yuewei Qian, Charles Rauch,[...]. Proc Natl Acad Sci U S A 2012
186
26

PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing.
Quan Zhao, Gerhard Rank, Yuen T Tan, Haitao Li, Robert L Moritz, Richard J Simpson, Loretta Cerruti, David J Curtis, Dinshaw J Patel, C David Allis,[...]. Nat Struct Mol Biol 2009
364
25

Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5.
Konstantinos J Mavrakis, E Robert McDonald, Michael R Schlabach, Eric Billy, Gregory R Hoffman, Antoine deWeck, David A Ruddy, Kavitha Venkatesan, Jianjun Yu, Gregg McAllister,[...]. Science 2016
212
25

Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation.
Lapo Alinari, Kiran V Mahasenan, Fengting Yan, Vrajesh Karkhanis, Ji-Hyun Chung, Emily M Smith, Carl Quinion, Porsha L Smith, Lisa Kim, John T Patton,[...]. Blood 2015
85
28

Genetic validation of the protein arginine methyltransferase PRMT5 as a candidate therapeutic target in glioblastoma.
Fengting Yan, Lapo Alinari, Mark E Lustberg, Ludmila Katherine Martin, Hector M Cordero-Nieves, Yeshavanth Banasavadi-Siddegowda, Selene Virk, Jill Barnholtz-Sloan, Erica Hlavin Bell, Jeffrey Wojton,[...]. Cancer Res 2014
91
25

MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells.
Gregory V Kryukov, Frederick H Wilson, Jason R Ruth, Joshiawa Paulk, Aviad Tsherniak, Sara E Marlow, Francisca Vazquez, Barbara A Weir, Mark E Fitzgerald, Minoru Tanaka,[...]. Science 2016
213
23

Arginine methylation controls growth regulation by E2F-1.
Er-Chieh Cho, Shunsheng Zheng, Shonagh Munro, Geng Liu, Simon M Carr, Jutta Moehlenbrink, Yi-Chien Lu, Lindsay Stimson, Omar Khan, Rebecca Konietzny,[...]. EMBO J 2012
137
21

The dual epigenetic role of PRMT5 in acute myeloid leukemia: gene activation and repression via histone arginine methylation.
S S Tarighat, R Santhanam, D Frankhouser, H S Radomska, H Lai, M Anghelina, H Wang, X Huang, L Alinari, A Walker,[...]. Leukemia 2016
90
23

PRMT5 dimethylates R30 of the p65 subunit to activate NF-κB.
Han Wei, Benlian Wang, Masaru Miyagi, Yun She, Banu Gopalan, De-Bin Huang, Gourisankar Ghosh, George R Stark, Tao Lu. Proc Natl Acad Sci U S A 2013
132
19

MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis.
Cheryl M Koh, Marco Bezzi, Diana H P Low, Wei Xia Ang, Shun Xie Teo, Florence P H Gay, Muthafar Al-Haddawi, Soo Yong Tan, Motomi Osato, Arianna Sabò,[...]. Nature 2015
203
18

Protein arginine methyltransferase 5 (PRMT5) inhibition induces lymphoma cell death through reactivation of the retinoblastoma tumor suppressor pathway and polycomb repressor complex 2 (PRC2) silencing.
Jihyun Chung, Vrajesh Karkhanis, Sookil Tae, Fengting Yan, Porsha Smith, Leona W Ayers, Claudio Agostinelli, Stefano Pileri, Gerald V Denis, Robert A Baiocchi,[...]. J Biol Chem 2013
63
26

Arginine methyltransferase PRMT5 is essential for sustaining normal adult hematopoiesis.
Fan Liu, Guoyan Cheng, Pierre-Jacques Hamard, Sarah Greenblatt, Lan Wang, Na Man, Fabiana Perna, Haiming Xu, Madhavi Tadi, Luisa Luciani,[...]. J Clin Invest 2015
81
20

LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity.
Zahid Q Bonday, Guillermo S Cortez, Michael J Grogan, Stephen Antonysamy, Ken Weichert, Wayne P Bocchinfuso, Fengling Li, Steven Kennedy, Binghui Li, Mary M Mader,[...]. ACS Med Chem Lett 2018
66
25

Protein arginine methyltransferase 5 functions as an epigenetic activator of the androgen receptor to promote prostate cancer cell growth.
X Deng, G Shao, H-T Zhang, C Li, D Zhang, L Cheng, B D Elzey, R Pili, T L Ratliff, J Huang,[...]. Oncogene 2017
67
25

Protein arginine methyltransferase 5 accelerates tumor growth by arginine methylation of the tumor suppressor programmed cell death 4.
Matthew A Powers, Marta M Fay, Rachel E Factor, Alana L Welm, Katharine S Ullman. Cancer Res 2011
97
16

Protein arginine methyltransferase 5 is a potential oncoprotein that upregulates G1 cyclins/cyclin-dependent kinases and the phosphoinositide 3-kinase/AKT signaling cascade.
Tong-You W Wei, Chi-Chang Juan, Jiun-Yi Hisa, Li-Jen Su, Yuan-Chii G Lee, Hsiang-Yun Chou, Jo-Mei M Chen, Yu-Chung Wu, Shao-Chih Chiu, Chung-Ping Hsu,[...]. Cancer Sci 2012
126
16

Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666.
Kenneth W Duncan, Nathalie Rioux, P Ann Boriack-Sjodin, Michael J Munchhof, Lawrence A Reiter, Christina R Majer, Lei Jin, L Danielle Johnston, Elayne Chan-Penebre, Kristy G Kuplast,[...]. ACS Med Chem Lett 2015
67
23


Targeting methyltransferase PRMT5 eliminates leukemia stem cells in chronic myelogenous leukemia.
Yanli Jin, Jingfeng Zhou, Fang Xu, Bei Jin, Lijing Cui, Yun Wang, Xin Du, Juan Li, Peng Li, Ruibao Ren,[...]. J Clin Invest 2016
91
17

MTAP Deletions in Cancer Create Vulnerability to Targeting of the MAT2A/PRMT5/RIOK1 Axis.
Katya Marjon, Michael J Cameron, Phong Quang, Michelle F Clasquin, Everton Mandley, Kaiko Kunii, Michael McVay, Sung Choe, Andrew Kernytsky, Stefan Gross,[...]. Cell Rep 2016
147
16

Protein arginine methyltransferase 5 is essential for growth of lung cancer cells.
Zhongping Gu, Shen Gao, Fahao Zhang, Zhiqiang Wang, Wencai Ma, Richard E Davis, Zhengxin Wang. Biochem J 2012
93
16

The methylosome, a 20S complex containing JBP1 and pICln, produces dimethylarginine-modified Sm proteins.
W J Friesen, S Paushkin, A Wyce, S Massenet, G S Pesiridis, G Van Duyne, J Rappsilber, M Mann, G Dreyfuss. Mol Cell Biol 2001
305
15

Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery.
Marco Bezzi, Shun Xie Teo, Julius Muller, Wei Chuen Mok, Sanjeeb Kumar Sahu, Leah A Vardy, Zahid Q Bonday, Ernesto Guccione. Genes Dev 2013
152
15

PRMT5-PTEN molecular pathway regulates senescence and self-renewal of primary glioblastoma neurosphere cells.
Y K Banasavadi-Siddegowda, L Russell, E Frair, V A Karkhanis, T Relation, J Y Yoo, J Zhang, S Sif, J Imitola, R Baiocchi,[...]. Oncogene 2017
67
22

Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma.
Christian J Braun, Monica Stanciu, Paul L Boutz, Jesse C Patterson, David Calligaris, Fumi Higuchi, Rachit Neupane, Silvia Fenoglio, Daniel P Cahill, Hiroaki Wakimoto,[...]. Cancer Cell 2017
95
15

PRMT5 methylome profiling uncovers a direct link to splicing regulation in acute myeloid leukemia.
Aliaksandra Radzisheuskaya, Pavel V Shliaha, Vasily Grinev, Eugenia Lorenzini, Sergey Kovalchuk, Daria Shlyueva, Vladimir Gorshkov, Ronald C Hendrickson, Ole N Jensen, Kristian Helin. Nat Struct Mol Biol 2019
51
29

Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation.
Jung-Mao Hsu, Chun-Te Chen, Chao-Kai Chou, Hsu-Ping Kuo, Long-Yuan Li, Chun-Yi Lin, Hong-Jen Lee, Ying-Nai Wang, Mo Liu, Hsin-Wei Liao,[...]. Nat Cell Biol 2011
149
14


Overexpression of PRMT5 promotes tumor cell growth and is associated with poor disease prognosis in epithelial ovarian cancer.
Xiangxiang Bao, Shan Zhao, Ting Liu, Yang Liu, Yueyang Liu, Xingsheng Yang. J Histochem Cytochem 2013
81
16

PRMT5 is required for lymphomagenesis triggered by multiple oncogenic drivers.
Yan Li, Nilesh Chitnis, Hiroshi Nakagawa, Yoshiaki Kita, Shoji Natsugoe, Yi Yang, Zihai Li, Mariusz Wasik, Andres J P Klein-Szanto, Anil K Rustgi,[...]. Cancer Discov 2015
89
14

PRMT9 is a type II methyltransferase that methylates the splicing factor SAP145.
Yanzhong Yang, Andrea Hadjikyriacou, Zheng Xia, Sitaram Gayatri, Daehoon Kim, Cecilia Zurita-Lopez, Ryan Kelly, Ailan Guo, Wei Li, Steven G Clarke,[...]. Nat Commun 2015
124
13

Methylation of Sm proteins by a complex containing PRMT5 and the putative U snRNP assembly factor pICln.
G Meister, C Eggert, D Bühler, H Brahms, C Kambach, U Fischer. Curr Biol 2001
256
13

Protein arginine methyltransferase 5 (PRMT5) dysregulation in cancer.
Harshita Shailesh, Zain Z Zakaria, Robert Baiocchi, Saïd Sif. Oncotarget 2018
48
27

PRMT5 Is a Critical Regulator of Breast Cancer Stem Cell Function via Histone Methylation and FOXP1 Expression.
Kelly Chiang, Agnieszka E Zielinska, Abeer M Shaaban, Maria Pilar Sanchez-Bailon, James Jarrold, Thomas L Clarke, Jingxian Zhang, Adele Francis, Louise J Jones, Sally Smith,[...]. Cell Rep 2017
74
16

HOXA9 methylation by PRMT5 is essential for endothelial cell expression of leukocyte adhesion molecules.
Smarajit Bandyopadhyay, Daniel P Harris, Gregory N Adams, Gregory E Lause, Anne McHugh, Emily G Tillmaand, Angela Money, Belinda Willard, Paul L Fox, Paul E Dicorleto. Mol Cell Biol 2012
56
19

Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis.
Dong Hu, Mert Gur, Zhuan Zhou, Armin Gamper, Mien-Chie Hung, Naoya Fujita, Li Lan, Ivet Bahar, Yong Wan. Nat Commun 2015
75
14

PRMT5 (Janus kinase-binding protein 1) catalyzes the formation of symmetric dimethylarginine residues in proteins.
T L Branscombe, A Frankel, J H Lee, J R Cook, Z Yang , S Pestka, S Clarke. J Biol Chem 2001
281
11

Histone H2A and H4 N-terminal tails are positioned by the MEP50 WD repeat protein for efficient methylation by the PRMT5 arginine methyltransferase.
Emmanuel S Burgos, Carola Wilczek, Takashi Onikubo, Jeffrey B Bonanno, Janina Jansong, Ulf Reimer, David Shechter. J Biol Chem 2015
52
21

Targeting protein arginine methyltransferase 5 inhibits colorectal cancer growth by decreasing arginine methylation of eIF4E and FGFR3.
Baolai Zhang, Shuhong Dong, Ruiming Zhu, Chunyan Hu, Jing Hou, Yan Li, Qian Zhao, Xue Shao, Qian Bu, Hongyu Li,[...]. Oncotarget 2015
58
18

Potent, Selective, and Cell Active Protein Arginine Methyltransferase 5 (PRMT5) Inhibitor Developed by Structure-Based Virtual Screening and Hit Optimization.
Ruifeng Mao, Jingwei Shao, Kongkai Zhu, Yuanyuan Zhang, Hong Ding, Chenhua Zhang, Zhe Shi, Hualiang Jiang, Dequn Sun, Wenhu Duan,[...]. J Med Chem 2017
32
34


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.