Christoph van Thriel, Remco H S Westerink, Christian Beste, Ambuja S Bale, Pamela J Lein, Marcel Leist. Neurotoxicology 2012
Times Cited: 69
Times Cited: 69
Times Cited
Times Co-cited
Similarity
Compound selection for in vitro modeling of developmental neurotoxicity.
Suzanne Kadereit, Bastian Zimmer, Christoph van Thriel, Jan G Hengstler, Marcel Leist. Front Biosci (Landmark Ed) 2012
Suzanne Kadereit, Bastian Zimmer, Christoph van Thriel, Jan G Hengstler, Marcel Leist. Front Biosci (Landmark Ed) 2012
50
Evaluation of developmental toxicants and signaling pathways in a functional test based on the migration of human neural crest cells.
Bastian Zimmer, Gabsang Lee, Nina V Balmer, Kesavan Meganathan, Agapios Sachinidis, Lorenz Studer, Marcel Leist. Environ Health Perspect 2012
Bastian Zimmer, Gabsang Lee, Nina V Balmer, Kesavan Meganathan, Agapios Sachinidis, Lorenz Studer, Marcel Leist. Environ Health Perspect 2012
39
Assessment of chemical-induced impairment of human neurite outgrowth by multiparametric live cell imaging in high-density cultures.
Nina V Stiegler, Anne K Krug, Florian Matt, Marcel Leist. Toxicol Sci 2011
Nina V Stiegler, Anne K Krug, Florian Matt, Marcel Leist. Toxicol Sci 2011
37
Evaluation of a human neurite growth assay as specific screen for developmental neurotoxicants.
Anne K Krug, Nina V Balmer, Florian Matt, Felix Schönenberger, Dorit Merhof, Marcel Leist. Arch Toxicol 2013
Anne K Krug, Nina V Balmer, Florian Matt, Felix Schönenberger, Dorit Merhof, Marcel Leist. Arch Toxicol 2013
34
Coordinated waves of gene expression during neuronal differentiation of embryonic stem cells as basis for novel approaches to developmental neurotoxicity testing.
B Zimmer, P B Kuegler, B Baudis, A Genewsky, V Tanavde, W Koh, B Tan, T Waldmann, S Kadereit, M Leist. Cell Death Differ 2011
B Zimmer, P B Kuegler, B Baudis, A Genewsky, V Tanavde, W Koh, B Tan, T Waldmann, S Kadereit, M Leist. Cell Death Differ 2011
33
The dawning of a new age of toxicology.
Marcel Leist, Thomas Hartung, Pierluigi Nicotera. ALTEX 2008
Marcel Leist, Thomas Hartung, Pierluigi Nicotera. ALTEX 2008
33
Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach.
Anne K Krug, Raivo Kolde, John A Gaspar, Eugen Rempel, Nina V Balmer, Kesavan Meganathan, Kinga Vojnits, Mathurin Baquié, Tanja Waldmann, Roberto Ensenat-Waser,[...]. Arch Toxicol 2013
Anne K Krug, Raivo Kolde, John A Gaspar, Eugen Rempel, Nina V Balmer, Kesavan Meganathan, Kinga Vojnits, Mathurin Baquié, Tanja Waldmann, Roberto Ensenat-Waser,[...]. Arch Toxicol 2013
33
Epigenetic changes and disturbed neural development in a human embryonic stem cell-based model relating to the fetal valproate syndrome.
Nina V Balmer, Matthias K Weng, Bastian Zimmer, Violeta N Ivanova, Stuart M Chambers, Elena Nikolaeva, Smita Jagtap, Agapios Sachinidis, Jürgen Hescheler, Tanja Waldmann,[...]. Hum Mol Genet 2012
Nina V Balmer, Matthias K Weng, Bastian Zimmer, Violeta N Ivanova, Stuart M Chambers, Elena Nikolaeva, Smita Jagtap, Agapios Sachinidis, Jürgen Hescheler, Tanja Waldmann,[...]. Hum Mol Genet 2012
31
Developmental neurotoxicity - challenges in the 21st century and in vitro opportunities.
Lena Smirnova, Helena T Hogberg, Marcel Leist, Thomas Hartung. ALTEX 2014
Lena Smirnova, Helena T Hogberg, Marcel Leist, Thomas Hartung. ALTEX 2014
31
Advancing the science of developmental neurotoxicity (DNT): testing for better safety evaluation.
Anna K Bal-Price, Sandra Coecke, Lucio Costa, Kevin M Crofton, Ellen Fritsche, Alan Goldberg, Philippe Grandjean, Pamela J Lein, Abby Li, Roberto Lucchini,[...]. ALTEX 2012
Anna K Bal-Price, Sandra Coecke, Lucio Costa, Kevin M Crofton, Ellen Fritsche, Alan Goldberg, Philippe Grandjean, Pamela J Lein, Abby Li, Roberto Lucchini,[...]. ALTEX 2012
30
Markers of murine embryonic and neural stem cells, neurons and astrocytes: reference points for developmental neurotoxicity testing.
Philipp B Kuegler, Bastian Zimmer, Tanja Waldmann, Birte Baudis, Sten Ilmjärv, Jürgen Hescheler, Phil Gaughwin, Patrik Brundin, William Mundy, Anna K Bal-Price,[...]. ALTEX 2010
Philipp B Kuegler, Bastian Zimmer, Tanja Waldmann, Birte Baudis, Sten Ilmjärv, Jürgen Hescheler, Phil Gaughwin, Patrik Brundin, William Mundy, Anna K Bal-Price,[...]. ALTEX 2010
28
Food for thought ... considerations and guidelines for basic test method descriptions in toxicology.
Marcel Leist, Liudmila Efremova, Christiaan Karreman. ALTEX 2010
Marcel Leist, Liudmila Efremova, Christiaan Karreman. ALTEX 2010
40
International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes.
Anna Bal-Price, Kevin M Crofton, Marcel Leist, Sandra Allen, Michael Arand, Timo Buetler, Nathalie Delrue, Rex E FitzGerald, Thomas Hartung, Tuula Heinonen,[...]. Arch Toxicol 2015
Anna Bal-Price, Kevin M Crofton, Marcel Leist, Sandra Allen, Michael Arand, Timo Buetler, Nathalie Delrue, Rex E FitzGerald, Thomas Hartung, Tuula Heinonen,[...]. Arch Toxicol 2015
26
24
Developmental neurotoxicity testing: a path forward.
Kevin M Crofton, William R Mundy, Timothy J Shafer. Congenit Anom (Kyoto) 2012
Kevin M Crofton, William R Mundy, Timothy J Shafer. Congenit Anom (Kyoto) 2012
23
Consensus report on the future of animal-free systemic toxicity testing.
Marcel Leist, Nina Hasiwa, Costanza Rovida, Mardas Daneshian, David Basketter, Ian Kimber, Harvey Clewell, Tilman Gocht, Alan Goldberg, Francois Busquet,[...]. ALTEX 2014
Marcel Leist, Nina Hasiwa, Costanza Rovida, Mardas Daneshian, David Basketter, Ian Kimber, Harvey Clewell, Tilman Gocht, Alan Goldberg, Francois Busquet,[...]. ALTEX 2014
21
Sensitivity of dopaminergic neuron differentiation from stem cells to chronic low-dose methylmercury exposure.
Bastian Zimmer, Stefan Schildknecht, Philipp B Kuegler, Vivek Tanavde, Suzanne Kadereit, Marcel Leist. Toxicol Sci 2011
Bastian Zimmer, Stefan Schildknecht, Philipp B Kuegler, Vivek Tanavde, Suzanne Kadereit, Marcel Leist. Toxicol Sci 2011
26
The biological and ethical basis of the use of human embryonic stem cells for in vitro test systems or cell therapy.
Marcel Leist, Susanne Bremer, Patrik Brundin, Juergen Hescheler, Agnete Kirkeby, Karl-Heinz Krause, Peter Poerzgen, Michel Puceat, Mathias Schmidt, Andre Schrattenholz,[...]. ALTEX 2008
Marcel Leist, Susanne Bremer, Patrik Brundin, Juergen Hescheler, Agnete Kirkeby, Karl-Heinz Krause, Peter Poerzgen, Michel Puceat, Mathias Schmidt, Andre Schrattenholz,[...]. ALTEX 2008
25
A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing.
David A Basketter, Harvey Clewell, Ian Kimber, Annamaria Rossi, Bas Blaauboer, Robert Burrier, Mardas Daneshian, Chantra Eskes, Alan Goldberg, Nina Hasiwa,[...]. ALTEX 2012
David A Basketter, Harvey Clewell, Ian Kimber, Annamaria Rossi, Bas Blaauboer, Robert Burrier, Mardas Daneshian, Chantra Eskes, Alan Goldberg, Nina Hasiwa,[...]. ALTEX 2012
20
In vitro developmental neurotoxicity (DNT) testing: relevant models and endpoints.
Anna K Bal-Price, Helena T Hogberg, Leonora Buzanska, Petros Lenas, Erwin van Vliet, Thomas Hartung. Neurotoxicology 2010
Anna K Bal-Price, Helena T Hogberg, Leonora Buzanska, Petros Lenas, Erwin van Vliet, Thomas Hartung. Neurotoxicology 2010
19
Design principles of concentration-dependent transcriptome deviations in drug-exposed differentiating stem cells.
Tanja Waldmann, Eugen Rempel, Nina V Balmer, André König, Raivo Kolde, John Antonydas Gaspar, Margit Henry, Jürgen Hescheler, Agapios Sachinidis, Jörg Rahnenführer,[...]. Chem Res Toxicol 2014
Tanja Waldmann, Eugen Rempel, Nina V Balmer, André König, Raivo Kolde, John Antonydas Gaspar, Margit Henry, Jürgen Hescheler, Agapios Sachinidis, Jörg Rahnenführer,[...]. Chem Res Toxicol 2014
18
Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test battery.
B Zimmer, G Pallocca, N Dreser, S Foerster, T Waldmann, J Westerhout, S Julien, K H Krause, C van Thriel, J G Hengstler,[...]. Arch Toxicol 2014
B Zimmer, G Pallocca, N Dreser, S Foerster, T Waldmann, J Westerhout, S Julien, K H Krause, C van Thriel, J G Hengstler,[...]. Arch Toxicol 2014
23
Putative adverse outcome pathways relevant to neurotoxicity.
Anna Bal-Price, Kevin M Crofton, Magdalini Sachana, Timothy J Shafer, Mamta Behl, Anna Forsby, Alan Hargreaves, Brigitte Landesmann, Pamela J Lein, Jochem Louisse,[...]. Crit Rev Toxicol 2015
Anna Bal-Price, Kevin M Crofton, Magdalini Sachana, Timothy J Shafer, Mamta Behl, Anna Forsby, Alan Hargreaves, Brigitte Landesmann, Pamela J Lein, Jochem Louisse,[...]. Crit Rev Toxicol 2015
18
Workgroup report: incorporating in vitro alternative methods for developmental neurotoxicity into international hazard and risk assessment strategies.
Sandra Coecke, Alan M Goldberg, Sandra Allen, Leonora Buzanska, Gemma Calamandrei, Kevin Crofton, Lars Hareng, Thomas Hartung, Holger Knaut, Paul Honegger,[...]. Environ Health Perspect 2007
Sandra Coecke, Alan M Goldberg, Sandra Allen, Leonora Buzanska, Gemma Calamandrei, Kevin Crofton, Lars Hareng, Thomas Hartung, Holger Knaut, Paul Honegger,[...]. Environ Health Perspect 2007
17
Developmental neurotoxicity testing: recommendations for developing alternative methods for the screening and prioritization of chemicals.
Kevin M Crofton, William R Mundy, Pamela J Lein, Anna Bal-Price, Sandra Coecke, Andrea E M Seiler, Holger Knaut, Leonora Buzanska, Alan Goldberg. ALTEX 2011
Kevin M Crofton, William R Mundy, Pamela J Lein, Anna Bal-Price, Sandra Coecke, Andrea E M Seiler, Holger Knaut, Leonora Buzanska, Alan Goldberg. ALTEX 2011
17
Additive effects of caspase inhibitor and lazaroid on the survival of transplanted rat and human embryonic dopamine neurons.
O Hansson, R F Castilho, G S Kaminski Schierle, J Karlsson, P Nicotera, M Leist, P Brundin. Exp Neurol 2000
O Hansson, R F Castilho, G S Kaminski Schierle, J Karlsson, P Nicotera, M Leist, P Brundin. Exp Neurol 2000
17
Metabolomics in toxicology and preclinical research.
Tzutzuy Ramirez, Mardas Daneshian, Hennicke Kamp, Frederic Y Bois, Malcolm R Clench, Muireann Coen, Beth Donley, Steven M Fischer, Drew R Ekman, Eric Fabian,[...]. ALTEX 2013
Tzutzuy Ramirez, Mardas Daneshian, Hennicke Kamp, Frederic Y Bois, Malcolm R Clench, Muireann Coen, Beth Donley, Steven M Fischer, Drew R Ekman, Eric Fabian,[...]. ALTEX 2013
17
Adverse outcome pathways: a conceptual framework to support ecotoxicology research and risk assessment.
Gerald T Ankley, Richard S Bennett, Russell J Erickson, Dale J Hoff, Michael W Hornung, Rodney D Johnson, David R Mount, John W Nichols, Christine L Russom, Patricia K Schmieder,[...]. Environ Toxicol Chem 2010
Gerald T Ankley, Richard S Bennett, Russell J Erickson, Dale J Hoff, Michael W Hornung, Rodney D Johnson, David R Mount, John W Nichols, Christine L Russom, Patricia K Schmieder,[...]. Environ Toxicol Chem 2010
15
Rapid, complete and large-scale generation of post-mitotic neurons from the human LUHMES cell line.
Diana Scholz, Dominik Pöltl, Andreas Genewsky, Matthias Weng, Tanja Waldmann, Stefan Schildknecht, Marcel Leist. J Neurochem 2011
Diana Scholz, Dominik Pöltl, Andreas Genewsky, Matthias Weng, Tanja Waldmann, Stefan Schildknecht, Marcel Leist. J Neurochem 2011
15
The use of biomarkers of toxicity for integrating in vitro hazard estimates into risk assessment for humans.
Bas J Blaauboer, Kim Boekelheide, Harvey J Clewell, Mardas Daneshian, Milou M L Dingemans, Alan M Goldberg, Marjoke Heneweer, Joanna Jaworska, Nynke I Kramer, Marcel Leist,[...]. ALTEX 2012
Bas J Blaauboer, Kim Boekelheide, Harvey J Clewell, Mardas Daneshian, Milou M L Dingemans, Alan M Goldberg, Marjoke Heneweer, Joanna Jaworska, Nynke I Kramer, Marcel Leist,[...]. ALTEX 2012
15
ATP controls neuronal apoptosis triggered by microtubule breakdown or potassium deprivation.
C Volbracht, M Leist, P Nicotera. Mol Med 1999
C Volbracht, M Leist, P Nicotera. Mol Med 1999
15
Epigenetics and transcriptomics to detect adverse drug effects in model systems of human development.
Nina V Balmer, Marcel Leist. Basic Clin Pharmacol Toxicol 2014
Nina V Balmer, Marcel Leist. Basic Clin Pharmacol Toxicol 2014
40
From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects.
Nina V Balmer, Stefanie Klima, Eugen Rempel, Violeta N Ivanova, Raivo Kolde, Matthias K Weng, Kesavan Meganathan, Margit Henry, Agapios Sachinidis, Michael R Berthold,[...]. Arch Toxicol 2014
Nina V Balmer, Stefanie Klima, Eugen Rempel, Violeta N Ivanova, Raivo Kolde, Matthias K Weng, Kesavan Meganathan, Margit Henry, Agapios Sachinidis, Michael R Berthold,[...]. Arch Toxicol 2014
18
A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors.
Eugen Rempel, Lisa Hoelting, Tanja Waldmann, Nina V Balmer, Stefan Schildknecht, Marianna Grinberg, John Antony Das Gaspar, Vaibhav Shinde, Regina Stöber, Rosemarie Marchan,[...]. Arch Toxicol 2015
Eugen Rempel, Lisa Hoelting, Tanja Waldmann, Nina V Balmer, Stefan Schildknecht, Marianna Grinberg, John Antony Das Gaspar, Vaibhav Shinde, Regina Stöber, Rosemarie Marchan,[...]. Arch Toxicol 2015
16
Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use.
Michael Aschner, Sandra Ceccatelli, Mardas Daneshian, Ellen Fritsche, Nina Hasiwa, Thomas Hartung, Helena T Hogberg, Marcel Leist, Abby Li, William R Mundi,[...]. ALTEX 2017
Michael Aschner, Sandra Ceccatelli, Mardas Daneshian, Ellen Fritsche, Nina Hasiwa, Thomas Hartung, Helena T Hogberg, Marcel Leist, Abby Li, William R Mundi,[...]. ALTEX 2017
15
OECD/EFSA workshop on developmental neurotoxicity (DNT): The use of non-animal test methods for regulatory purposes.
Ellen Fritsche, Kevin M Crofton, Antonio F Hernandez, Susanne Hougaard Bennekou, Marcel Leist, Anna Bal-Price, Elissa Reaves, Martin F Wilks, Andrea Terron, Roland Solecki,[...]. ALTEX 2017
Ellen Fritsche, Kevin M Crofton, Antonio F Hernandez, Susanne Hougaard Bennekou, Marcel Leist, Anna Bal-Price, Elissa Reaves, Martin F Wilks, Andrea Terron, Roland Solecki,[...]. ALTEX 2017
19
Human neurospheres as three-dimensional cellular systems for developmental neurotoxicity testing.
Michaela Moors, Thomas Dino Rockel, Josef Abel, Jason E Cline, Kathrin Gassmann, Timm Schreiber, Janette Schuwald, Nicole Weinmann, Ellen Fritsche. Environ Health Perspect 2009
Michaela Moors, Thomas Dino Rockel, Josef Abel, Jason E Cline, Kathrin Gassmann, Timm Schreiber, Janette Schuwald, Nicole Weinmann, Ellen Fritsche. Environ Health Perspect 2009
14
Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models.
D Rice, S Barone. Environ Health Perspect 2000
D Rice, S Barone. Environ Health Perspect 2000
14
Use of high content image analysis to detect chemical-induced changes in synaptogenesis in vitro.
Joshua A Harrill, Brian L Robinette, William R Mundy. Toxicol In Vitro 2011
Joshua A Harrill, Brian L Robinette, William R Mundy. Toxicol In Vitro 2011
14
Metabolic depletion of ATP by fructose inversely controls CD95- and tumor necrosis factor receptor 1-mediated hepatic apoptosis.
M Latta, G Künstle, M Leist, A Wendel. J Exp Med 2000
M Latta, G Künstle, M Leist, A Wendel. J Exp Med 2000
14
Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.
Sarah Adler, David Basketter, Stuart Creton, Olavi Pelkonen, Jan van Benthem, Valérie Zuang, Klaus Ejner Andersen, Alexandre Angers-Loustau, Aynur Aptula, Anna Bal-Price,[...]. Arch Toxicol 2011
Sarah Adler, David Basketter, Stuart Creton, Olavi Pelkonen, Jan van Benthem, Valérie Zuang, Klaus Ejner Andersen, Alexandre Angers-Loustau, Aynur Aptula, Anna Bal-Price,[...]. Arch Toxicol 2011
14
Food for thought ... on the evolution of toxicology and the phasing out of animal testing.
Thomas Hartung, Marcel Leist. ALTEX 2008
Thomas Hartung, Marcel Leist. ALTEX 2008
14
A retrospective performance assessment of the developmental neurotoxicity study in support of OECD test guideline 426.
Susan L Makris, Kathleen Raffaele, Sandra Allen, Wayne J Bowers, Ulla Hass, Enrico Alleva, Gemma Calamandrei, Larry Sheets, Patric Amcoff, Nathalie Delrue,[...]. Environ Health Perspect 2009
Susan L Makris, Kathleen Raffaele, Sandra Allen, Wayne J Bowers, Ulla Hass, Enrico Alleva, Gemma Calamandrei, Larry Sheets, Patric Amcoff, Nathalie Delrue,[...]. Environ Health Perspect 2009
14
Hazard assessment of methylmercury toxicity to neuronal induction in embryogenesis using human embryonic stem cells.
Tina C Stummann, Lars Hareng, Susanne Bremer. Toxicology 2009
Tina C Stummann, Lars Hareng, Susanne Bremer. Toxicology 2009
14
Quantitative assessment of neurite outgrowth in human embryonic stem cell-derived hN2 cells using automated high-content image analysis.
Joshua A Harrill, Theresa M Freudenrich, Dave W Machacek, Steven L Stice, William R Mundy. Neurotoxicology 2010
Joshua A Harrill, Theresa M Freudenrich, Dave W Machacek, Steven L Stice, William R Mundy. Neurotoxicology 2010
14
Novel technologies and an overall strategy to allow hazard assessment and risk prediction of chemicals, cosmetics, and drugs with animal-free methods.
Marcel Leist, Brett A Lidbury, Chihae Yang, Patrick J Hayden, Jens M Kelm, Stephanie Ringeissen, Ann Detroyer, Jean R Meunier, James F Rathman, George R Jackson,[...]. ALTEX 2012
Marcel Leist, Brett A Lidbury, Chihae Yang, Patrick J Hayden, Jens M Kelm, Stephanie Ringeissen, Ann Detroyer, Jean R Meunier, James F Rathman, George R Jackson,[...]. ALTEX 2012
28
Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP(+).
A K Krug, S Gutbier, L Zhao, D Pöltl, C Kullmann, V Ivanova, S Förster, S Jagtap, J Meiser, G Leparc,[...]. Cell Death Dis 2014
A K Krug, S Gutbier, L Zhao, D Pöltl, C Kullmann, V Ivanova, S Förster, S Jagtap, J Meiser, G Leparc,[...]. Cell Death Dis 2014
14
Neurobehavioural effects of developmental toxicity.
Philippe Grandjean, Philip J Landrigan. Lancet Neurol 2014
Philippe Grandjean, Philip J Landrigan. Lancet Neurol 2014
14
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.