Pablo Díaz-Amarilla, Silvia Olivera-Bravo, Emiliano Trias, Andrea Cragnolini, Laura Martínez-Palma, Patricia Cassina, Joseph Beckman, Luis Barbeito. Proc Natl Acad Sci U S A 2011
Times Cited: 118
Times Cited: 118
Times Cited
Times Co-cited
Similarity
Astrocytes from familial and sporadic ALS patients are toxic to motor neurons.
Amanda M Haidet-Phillips, Mark E Hester, Carlos J Miranda, Kathrin Meyer, Lyndsey Braun, Ashley Frakes, SungWon Song, Shibi Likhite, Matthew J Murtha, Kevin D Foust,[...]. Nat Biotechnol 2011
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Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons.
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Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis.
Koji Yamanaka, Seung Joo Chun, Severine Boillee, Noriko Fujimori-Tonou, Hirofumi Yamashita, David H Gutmann, Ryosuke Takahashi, Hidemi Misawa, Don W Cleveland. Nat Neurosci 2008
Koji Yamanaka, Seung Joo Chun, Severine Boillee, Noriko Fujimori-Tonou, Hirofumi Yamashita, David H Gutmann, Ryosuke Takahashi, Hidemi Misawa, Don W Cleveland. Nat Neurosci 2008
38
Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS).
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Onset and progression in inherited ALS determined by motor neurons and microglia.
Séverine Boillée, Koji Yamanaka, Christian S Lobsiger, Neal G Copeland, Nancy A Jenkins, George Kassiotis, George Kollias, Don W Cleveland. Science 2006
Séverine Boillée, Koji Yamanaka, Christian S Lobsiger, Neal G Copeland, Nancy A Jenkins, George Kassiotis, George Kollias, Don W Cleveland. Science 2006
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Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice.
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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation.
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Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model.
Francesco Paolo Di Giorgio, Monica A Carrasco, Michelle C Siao, Tom Maniatis, Kevin Eggan. Nat Neurosci 2007
Francesco Paolo Di Giorgio, Monica A Carrasco, Michelle C Siao, Tom Maniatis, Kevin Eggan. Nat Neurosci 2007
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ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.
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Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond.
Hristelina Ilieva, Magdalini Polymenidou, Don W Cleveland. J Cell Biol 2009
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ALS: a disease of motor neurons and their nonneuronal neighbors.
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Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells.
Maria C N Marchetto, Alysson R Muotri, Yangling Mu, Alan M Smith, Gabriela G Cezar, Fred H Gage. Cell Stem Cell 2008
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Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo.
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Phenotypic transition of microglia into astrocyte-like cells associated with disease onset in a model of inherited ALS.
Emiliano Trias, Pablo Díaz-Amarilla, Silvia Olivera-Bravo, Eugenia Isasi, Derek A Drechsel, Nathan Lopez, C Samuel Bradford, Kyle E Ireton, Joseph S Beckman, Luis Barbeito. Front Cell Neurosci 2013
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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis.
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21
Necroptosis drives motor neuron death in models of both sporadic and familial ALS.
Diane B Re, Virginia Le Verche, Changhao Yu, Mackenzie W Amoroso, Kristin A Politi, Sudarshan Phani, Burcin Ikiz, Lucas Hoffmann, Martijn Koolen, Tetsuya Nagata,[...]. Neuron 2014
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21
Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS.
Kathrin Meyer, Laura Ferraiuolo, Carlos J Miranda, Shibi Likhite, Sohyun McElroy, Samantha Renusch, Dara Ditsworth, Clotilde Lagier-Tourenne, Richard A Smith, John Ravits,[...]. Proc Natl Acad Sci U S A 2014
Kathrin Meyer, Laura Ferraiuolo, Carlos J Miranda, Shibi Likhite, Sohyun McElroy, Samantha Renusch, Dara Ditsworth, Clotilde Lagier-Tourenne, Richard A Smith, John Ravits,[...]. Proc Natl Acad Sci U S A 2014
21
Neurotoxic reactive astrocytes are induced by activated microglia.
Shane A Liddelow, Kevin A Guttenplan, Laura E Clarke, Frederick C Bennett, Christopher J Bohlen, Lucas Schirmer, Mariko L Bennett, Alexandra E Münch, Won-Suk Chung, Todd C Peterson,[...]. Nature 2017
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21
Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation.
Francesco Paolo Di Giorgio, Gabriella L Boulting, Samuel Bobrowicz, Kevin C Eggan. Cell Stem Cell 2008
Francesco Paolo Di Giorgio, Gabriella L Boulting, Samuel Bobrowicz, Kevin C Eggan. Cell Stem Cell 2008
20
Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants.
Patricia Cassina, Adriana Cassina, Mariana Pehar, Raquel Castellanos, Mandi Gandelman, Andrés de León, Kristine M Robinson, Ronald P Mason, Joseph S Beckman, Luis Barbeito,[...]. J Neurosci 2008
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19
Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis.
Ashley E Frakes, Laura Ferraiuolo, Amanda M Haidet-Phillips, Leah Schmelzer, Lyndsey Braun, Carlos J Miranda, Katherine J Ladner, Adam K Bevan, Kevin D Foust, Jonathan P Godbout,[...]. Neuron 2014
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19
Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy.
Andrea Serio, Bilada Bilican, Sami J Barmada, Dale Michael Ando, Chen Zhao, Rick Siller, Karen Burr, Ghazal Haghi, David Story, Agnes Lumi Nishimura,[...]. Proc Natl Acad Sci U S A 2013
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Focal degeneration of astrocytes in amyotrophic lateral sclerosis.
D Rossi, L Brambilla, C F Valori, C Roncoroni, A Crugnola, T Yokota, D E Bredesen, A Volterra. Cell Death Differ 2008
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17
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Post-paralysis tyrosine kinase inhibition with masitinib abrogates neuroinflammation and slows disease progression in inherited amyotrophic lateral sclerosis.
Emiliano Trias, Sofía Ibarburu, Romina Barreto-Núñez, Joël Babdor, Thiago T Maciel, Matthias Guillo, Laurent Gros, Patrice Dubreuil, Pablo Díaz-Amarilla, Patricia Cassina,[...]. J Neuroinflammation 2016
Emiliano Trias, Sofía Ibarburu, Romina Barreto-Núñez, Joël Babdor, Thiago T Maciel, Matthias Guillo, Laurent Gros, Patrice Dubreuil, Pablo Díaz-Amarilla, Patricia Cassina,[...]. J Neuroinflammation 2016
20
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS.
Mariely DeJesus-Hernandez, Ian R Mackenzie, Bradley F Boeve, Adam L Boxer, Matt Baker, Nicola J Rutherford, Alexandra M Nicholson, NiCole A Finch, Heather Flynn, Jennifer Adamson,[...]. Neuron 2011
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16
Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis.
Shin H Kang, Ying Li, Masahiro Fukaya, Ileana Lorenzini, Don W Cleveland, Lyle W Ostrow, Jeffrey D Rothstein, Dwight E Bergles. Nat Neurosci 2013
Shin H Kang, Ying Li, Masahiro Fukaya, Ileana Lorenzini, Don W Cleveland, Lyle W Ostrow, Jeffrey D Rothstein, Dwight E Bergles. Nat Neurosci 2013
16
Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease.
Thomas Philips, Wim Robberecht. Lancet Neurol 2011
Thomas Philips, Wim Robberecht. Lancet Neurol 2011
15
Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis.
David R Beers, Jenny S Henkel, Qin Xiao, Weihua Zhao, Jinghong Wang, Albert A Yen, Laszlo Siklos, Scott R McKercher, Stanley H Appel. Proc Natl Acad Sci U S A 2006
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15
Dysregulation of astrocyte-motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis.
Laura Ferraiuolo, Adrian Higginbottom, Paul R Heath, Sian Barber, David Greenald, Janine Kirby, Pamela J Shaw. Brain 2011
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15
Intricate interplay between astrocytes and motor neurons in ALS.
Hemali P Phatnani, Paolo Guarnieri, Brad A Friedman, Monica A Carrasco, Michael Muratet, Sean O'Keeffe, Chiamaka Nwakeze, Florencia Pauli-Behn, Kimberly M Newberry, Sarah K Meadows,[...]. Proc Natl Acad Sci U S A 2013
Hemali P Phatnani, Paolo Guarnieri, Brad A Friedman, Monica A Carrasco, Michael Muratet, Sean O'Keeffe, Chiamaka Nwakeze, Florencia Pauli-Behn, Kimberly M Newberry, Sarah K Meadows,[...]. Proc Natl Acad Sci U S A 2013
16
Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis.
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15
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD.
Alan E Renton, Elisa Majounie, Adrian Waite, Javier Simón-Sánchez, Sara Rollinson, J Raphael Gibbs, Jennifer C Schymick, Hannu Laaksovirta, John C van Swieten, Liisa Myllykangas,[...]. Neuron 2011
Alan E Renton, Elisa Majounie, Adrian Waite, Javier Simón-Sánchez, Sara Rollinson, J Raphael Gibbs, Jennifer C Schymick, Hannu Laaksovirta, John C van Swieten, Liisa Myllykangas,[...]. Neuron 2011
15
Genomic analysis of reactive astrogliosis.
Jennifer L Zamanian, Lijun Xu, Lynette C Foo, Navid Nouri, Lu Zhou, Rona G Giffard, Ben A Barres. J Neurosci 2012
Jennifer L Zamanian, Lijun Xu, Lynette C Foo, Navid Nouri, Lu Zhou, Rona G Giffard, Ben A Barres. J Neurosci 2012
15
A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis.
Luis H Barbeito, Mariana Pehar, Patricia Cassina, Marcelo R Vargas, Hugo Peluffo, Liliana Viera, Alvaro G Estévez, Joseph S Beckman. Brain Res Brain Res Rev 2004
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14
Connexin 43 in astrocytes contributes to motor neuron toxicity in amyotrophic lateral sclerosis.
Akshata A Almad, Arpitha Doreswamy, Sarah K Gross, Jean-Philippe Richard, Yuqing Huo, Norman Haughey, Nicholas J Maragakis. Glia 2016
Akshata A Almad, Arpitha Doreswamy, Sarah K Gross, Jean-Philippe Richard, Yuqing Huo, Norman Haughey, Nicholas J Maragakis. Glia 2016
17
Expression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in rats.
Jianbin Tong, Cao Huang, Fangfang Bi, Qinxue Wu, Bo Huang, Xionghao Liu, Fang Li, Hongxia Zhou, Xu-Gang Xia. EMBO J 2013
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13
Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS.
Oleg Butovsky, Shafiuddin Siddiqui, Galina Gabriely, Amanda J Lanser, Ben Dake, Gopal Murugaiyan, Camille E Doykan, Pauline M Wu, Reddy R Gali, Lakshmanan K Iyer,[...]. J Clin Invest 2012
Oleg Butovsky, Shafiuddin Siddiqui, Galina Gabriely, Amanda J Lanser, Ben Dake, Gopal Murugaiyan, Camille E Doykan, Pauline M Wu, Reddy R Gali, Lakshmanan K Iyer,[...]. J Clin Invest 2012
13
Mutant SOD1-expressing astrocytes release toxic factors that trigger motoneuron death by inducing hyperexcitability.
Elsa Fritz, Pamela Izaurieta, Alexandra Weiss, Franco R Mir, Patricio Rojas, David Gonzalez, Fabiola Rojas, Robert H Brown, Rodolfo Madrid, Brigitte van Zundert. J Neurophysiol 2013
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18
Increased glutathione biosynthesis by Nrf2 activation in astrocytes prevents p75NTR-dependent motor neuron apoptosis.
Marcelo R Vargas, Mariana Pehar, Patricia Cassina, Joseph S Beckman, Luis Barbeito. J Neurochem 2006
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13
Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease.
Angelo C Lepore, Britta Rauck, Christine Dejea, Andrea C Pardo, Mahendra S Rao, Jeffrey D Rothstein, Nicholas J Maragakis. Nat Neurosci 2008
Angelo C Lepore, Britta Rauck, Christine Dejea, Andrea C Pardo, Mahendra S Rao, Jeffrey D Rothstein, Nicholas J Maragakis. Nat Neurosci 2008
12
Astrocyte loss of mutant SOD1 delays ALS disease onset and progression in G85R transgenic mice.
Lijun Wang, David H Gutmann, Raymond P Roos. Hum Mol Genet 2011
Lijun Wang, David H Gutmann, Raymond P Roos. Hum Mol Genet 2011
12
Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS.
Bing Liao, Weihua Zhao, David R Beers, Jenny S Henkel, Stanley H Appel. Exp Neurol 2012
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12
A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model.
Isaac M Chiu, Emiko T A Morimoto, Hani Goodarzi, Jennifer T Liao, Sean O'Keeffe, Hemali P Phatnani, Michael Muratet, Michael C Carroll, Shawn Levy, Saeed Tavazoie,[...]. Cell Rep 2013
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12
12
Oligodendrocyte dysfunction in the pathogenesis of amyotrophic lateral sclerosis.
Thomas Philips, Andre Bento-Abreu, Annelies Nonneman, Wanda Haeck, Kim Staats, Veerle Geelen, Nicole Hersmus, Benno Küsters, Ludo Van Den Bosch, Philip Van Damme,[...]. Brain 2013
Thomas Philips, Andre Bento-Abreu, Annelies Nonneman, Wanda Haeck, Kim Staats, Veerle Geelen, Nicole Hersmus, Benno Küsters, Ludo Van Den Bosch, Philip Van Damme,[...]. Brain 2013
11
Mechanisms of Disease: astrocytes in neurodegenerative disease.
Nicholas J Maragakis, Jeffrey D Rothstein. Nat Clin Pract Neurol 2006
Nicholas J Maragakis, Jeffrey D Rothstein. Nat Clin Pract Neurol 2006
11
Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice.
Koji Yamanaka, Severine Boillee, Elizabeth A Roberts, Michael L Garcia, Melissa McAlonis-Downes, Oliver R Mikse, Don W Cleveland, Lawrence S B Goldstein. Proc Natl Acad Sci U S A 2008
Koji Yamanaka, Severine Boillee, Elizabeth A Roberts, Michael L Garcia, Melissa McAlonis-Downes, Oliver R Mikse, Don W Cleveland, Lawrence S B Goldstein. Proc Natl Acad Sci U S A 2008
11
Reactive Astrocytes Promote ALS-like Degeneration and Intracellular Protein Aggregation in Human Motor Neurons by Disrupting Autophagy through TGF-β1.
Pratibha Tripathi, Natalia Rodriguez-Muela, Joseph R Klim, A Sophie de Boer, Sahil Agrawal, Jackson Sandoe, Claudia S Lopes, Karolyn Sassi Ogliari, Luis A Williams, Matthew Shear,[...]. Stem Cell Reports 2017
Pratibha Tripathi, Natalia Rodriguez-Muela, Joseph R Klim, A Sophie de Boer, Sahil Agrawal, Jackson Sandoe, Claudia S Lopes, Karolyn Sassi Ogliari, Luis A Williams, Matthew Shear,[...]. Stem Cell Reports 2017
17
Extracellular mutant SOD1 induces microglial-mediated motoneuron injury.
Weihua Zhao, David R Beers, Jenny S Henkel, Wei Zhang, Makoto Urushitani, Jean-Pierre Julien, Stanley H Appel. Glia 2010
Weihua Zhao, David R Beers, Jenny S Henkel, Wei Zhang, Makoto Urushitani, Jean-Pierre Julien, Stanley H Appel. Glia 2010
10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.