A citation-based method for searching scientific literature

Diana C Blaydon, Paolo Biancheri, Wei-Li Di, Vincent Plagnol, Rita M Cabral, Matthew A Brooke, David A van Heel, Franz Ruschendorf, Mark Toynbee, Amanda Walne, Edel A O'Toole, Joanne E Martin, Keith Lindley, Tom Vulliamy, Dominic J Abrams, Thomas T MacDonald, John I Harper, David P Kelsell. N Engl J Med 2011
Times Cited: 219







List of co-cited articles
1226 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells.
R A Black, C T Rauch, C J Kozlosky, J J Peschon, J L Slack, M F Wolfson, B J Castner, K L Stocking, P Reddy, S Srinivasan,[...]. Nature 1997
34

An essential role for ectodomain shedding in mammalian development.
J J Peschon, J L Slack, P Reddy, K L Stocking, S W Sunnarborg, D C Lee, W E Russell, B J Castner, R S Johnson, J N Fitzner,[...]. Science 1998
33

Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice.
Athena Chalaris, Nina Adam, Christian Sina, Philip Rosenstiel, Judith Lehmann-Koch, Peter Schirmacher, Dieter Hartmann, Joanna Cichy, Olga Gavrilova, Stefan Schreiber,[...]. J Exp Med 2010
199
25

Inflammatory bowel disease and mutations affecting the interleukin-10 receptor.
Erik-Oliver Glocker, Daniel Kotlarz, Kaan Boztug, E Michael Gertz, Alejandro A Schäffer, Fatih Noyan, Mario Perro, Jana Diestelhorst, Anna Allroth, Dhaarini Murugan,[...]. N Engl J Med 2009
927
23

Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE.
Colin Adrain, Markus Zettl, Yonka Christova, Neil Taylor, Matthew Freeman. Science 2012
273
19

iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS.
David R McIlwain, Philipp A Lang, Thorsten Maretzky, Koichi Hamada, Kazuhito Ohishi, Sathish Kumar Maney, Thorsten Berger, Aditya Murthy, Gordon Duncan, Haifeng C Xu,[...]. Science 2012
228
19

The diagnostic approach to monogenic very early onset inflammatory bowel disease.
Holm H Uhlig, Tobias Schwerd, Sibylle Koletzko, Neil Shah, Jochen Kammermeier, Abdul Elkadri, Jodie Ouahed, David C Wilson, Simon P Travis, Dan Turner,[...]. Gastroenterology 2014
347
19

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha.
M L Moss, S L Jin, M E Milla, D M Bickett, W Burkhart, H L Carter, W J Chen, W C Clay, J R Didsbury, D Hassler,[...]. Nature 1997
19

Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands.
Umut Sahin, Gisela Weskamp, Kristine Kelly, Hong-Ming Zhou, Shigeki Higashiyama, Jacques Peschon, Dieter Hartmann, Paul Saftig, Carl P Blobel. J Cell Biol 2004
740
18

Cutting edge: TNF-alpha-converting enzyme (TACE/ADAM17) inactivation in mouse myeloid cells prevents lethality from endotoxin shock.
Keisuke Horiuchi, Tokuhiro Kimura, Takeshi Miyamoto, Hironari Takaishi, Yasunori Okada, Yoshiaki Toyama, Carl P Blobel. J Immunol 2007
243
18

ADAM17: a molecular switch to control inflammation and tissue regeneration.
Jürgen Scheller, Athena Chalaris, Christoph Garbers, Stefan Rose-John. Trends Immunol 2011
354
18

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Luke Jostins, Stephan Ripke, Rinse K Weersma, Richard H Duerr, Dermot P McGovern, Ken Y Hui, James C Lee, L Philip Schumm, Yashoda Sharma, Carl A Anderson,[...]. Nature 2012
18

iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling.
Xue Li, Thorsten Maretzky, Gisela Weskamp, Sébastien Monette, Xiaoping Qing, Priya Darshinee A Issuree, Howard C Crawford, David R McIlwain, Tak W Mak, Jane E Salmon,[...]. Proc Natl Acad Sci U S A 2015
94
18

iRHOM2 is a critical pathogenic mediator of inflammatory arthritis.
Priya Darshinee A Issuree, Thorsten Maretzky, David R McIlwain, Sébastien Monette, Xiaoping Qing, Philipp A Lang, Steven L Swendeman, Kyung-Hyun Park-Min, Nikolaus Binder, George D Kalliolias,[...]. J Clin Invest 2013
114
17

Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation.
Claus-Werner Franzke, Cristina Cobzaru, Antigoni Triantafyllopoulou, Stefanie Löffek, Keisuke Horiuchi, David W Threadgill, Thomas Kurz, Nico van Rooijen, Leena Bruckner-Tuderman, Carl P Blobel. J Exp Med 2012
117
17

Mutations in tetratricopeptide repeat domain 7A result in a severe form of very early onset inflammatory bowel disease.
Yaron Avitzur, Conghui Guo, Lucas A Mastropaolo, Ehsan Bahrami, Hannah Chen, Zhen Zhao, Abdul Elkadri, Sandeep Dhillon, Ryan Murchie, Ramzi Fattouh,[...]. Gastroenterology 2014
118
17

iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding.
Thorsten Maretzky, David R McIlwain, Priya Darshinee A Issuree, Xue Li, Jordi Malapeira, Sadaf Amin, Philipp A Lang, Tak W Mak, Carl P Blobel. Proc Natl Acad Sci U S A 2013
114
16

Making a definitive diagnosis: successful clinical application of whole exome sequencing in a child with intractable inflammatory bowel disease.
Elizabeth A Worthey, Alan N Mayer, Grant D Syverson, Daniel Helbling, Benedetta B Bonacci, Brennan Decker, Jaime M Serpe, Trivikram Dasu, Michael R Tschannen, Regan L Veith,[...]. Genet Med 2011
481
16

Loss of ADAM17 is associated with severe multiorgan dysfunction.
Robert H J Bandsma, Harry van Goor, Michael Yourshaw, Rudolf K Horlings, Marcel F Jonkman, Elisabeth H Schölvinck, Arend Karrenbeld, Rene Scheenstra, Martin Kömhoff, Patrick Rump,[...]. Hum Pathol 2015
24
66

ADAMs: key components in EGFR signalling and development.
Carl P Blobel. Nat Rev Mol Cell Biol 2005
846
14

ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site.
Sylvain M Le Gall, Thorsten Maretzky, Priya D A Issuree, Xiao-Da Niu, Karina Reiss, Paul Saftig, Rama Khokha, Daniel Lundell, Carl P Blobel. J Cell Sci 2010
144
13

Infant colitis--it's in the genes.
Erik-Oliver Glocker, Natalie Frede, Mario Perro, Neil Sebire, Mamoun Elawad, Neil Shah, Bodo Grimbacher. Lancet 2010
184
13

Loss of interleukin-10 signaling and infantile inflammatory bowel disease: implications for diagnosis and therapy.
Daniel Kotlarz, Rita Beier, Dhaarini Murugan, Jana Diestelhorst, Ole Jensen, Kaan Boztug, Dietmar Pfeifer, Hans Kreipe, Eva-Doreen Pfister, Ulrich Baumann,[...]. Gastroenterology 2012
281
13

Phosphatidylserine exposure is required for ADAM17 sheddase function.
Anselm Sommer, Felix Kordowski, Joscha Büch, Thorsten Maretzky, Astrid Evers, Jörg Andrä, Stefan Düsterhöft, Matthias Michalek, Inken Lorenzen, Prasath Somasundaram,[...]. Nat Commun 2016
100
13

Variants in TRIM22 That Affect NOD2 Signaling Are Associated With Very-Early-Onset Inflammatory Bowel Disease.
Qi Li, Cheng Hiang Lee, Lauren A Peters, Lucas A Mastropaolo, Cornelia Thoeni, Abdul Elkadri, Tobias Schwerd, Jun Zhu, Bin Zhang, Yongzhong Zhao,[...]. Gastroenterology 2016
64
20

Functional analysis of the domain structure of tumor necrosis factor-alpha converting enzyme.
P Reddy, J L Slack, R Davis, D P Cerretti, C J Kozlosky, R A Blanton, D Shows, J J Peschon, R A Black. J Biol Chem 2000
414
12

iRhom2 is required for the secretion of mouse TNFα.
Owen M Siggs, Nengming Xiao, Ying Wang, Hexin Shi, Wataru Tomisato, Xiaohong Li, Yu Xia, Bruce Beutler. Blood 2012
65
18


The shedding protease ADAM17: Physiology and pathophysiology.
Friederike Zunke, Stefan Rose-John. Biochim Biophys Acta Mol Cell Res 2017
138
12

Phosphorylation of iRhom2 Controls Stimulated Proteolytic Shedding by the Metalloprotease ADAM17/TACE.
Miguel Cavadas, Ioanna Oikonomidi, Catarina J Gaspar, Emma Burbridge, Marina Badenes, Inês Félix, Alfonso Bolado, Tianyi Hu, Andrea Bileck, Christopher Gerner,[...]. Cell Rep 2017
55
21

TACE activation by MAPK-mediated regulation of cell surface dimerization and TIMP3 association.
Pinglong Xu, Jianming Liu, Masayo Sakaki-Yumoto, Rik Derynck. Sci Signal 2012
105
11

XIAP variants in male Crohn's disease.
Yvonne Zeissig, Britt-Sabina Petersen, Snezana Milutinovic, Esther Bosse, Gabriele Mayr, Kenneth Peuker, Jelka Hartwig, Andreas Keller, Martina Kohl, Martin W Laass,[...]. Gut 2015
109
11

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
Jimmy Z Liu, Suzanne van Sommeren, Hailiang Huang, Siew C Ng, Rudi Alberts, Atsushi Takahashi, Stephan Ripke, James C Lee, Luke Jostins, Tejas Shah,[...]. Nat Genet 2015
11

Familial diarrhea syndrome caused by an activating GUCY2C mutation.
Torunn Fiskerstrand, Najla Arshad, Bjørn Ivar Haukanes, Rune Rose Tronstad, Khanh Do-Cong Pham, Stefan Johansson, Bjarte Håvik, Siv L Tønder, Shawn E Levy, Damien Brackman,[...]. N Engl J Med 2012
126
11

Phosphorylation of iRhom2 at the plasma membrane controls mammalian TACE-dependent inflammatory and growth factor signalling.
Adam Graham Grieve, Hongmei Xu, Ulrike Künzel, Paul Bambrough, Boris Sieber, Matthew Freeman. Elife 2017
66
16

Mammalian iRhoms have distinct physiological functions including an essential role in TACE regulation.
Yonka Christova, Colin Adrain, Paul Bambrough, Ashraf Ibrahim, Matthew Freeman. EMBO Rep 2013
92
10

Membrane-proximal domain of a disintegrin and metalloprotease-17 represents the putative molecular switch of its shedding activity operated by protein-disulfide isomerase.
Stefan Düsterhöft, Sascha Jung, Chien-Wen Hung, Andreas Tholey, Frank D Sönnichsen, Joachim Grötzinger, Inken Lorenzen. J Am Chem Soc 2013
59
16

Thiol isomerases negatively regulate the cellular shedding activity of ADAM17.
Sofie H Willems, Christopher J Tape, Peter L Stanley, Neil A Taylor, Ian G Mills, David E Neal, John McCafferty, Gillian Murphy. Biochem J 2010
134
10

Short-term TNFα shedding is independent of cytoplasmic phosphorylation or furin cleavage of ADAM17.
Jeanette Schwarz, Claudia Broder, Ansgard Helmstetter, Stefanie Schmidt, Isabell Yan, Miryam Müller, Dirk Schmidt-Arras, Christoph Becker-Pauly, Friedrich Koch-Nolte, Hans-Willi Mittrücker,[...]. Biochim Biophys Acta 2013
39
25

Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation.
Neil Romberg, Khatoun Al Moussawi, Carol Nelson-Williams, Amy L Stiegler, Erin Loring, Murim Choi, John Overton, Eric Meffre, Mustafa K Khokha, Anita J Huttner,[...]. Nat Genet 2014
285
10

A hypermorphic missense mutation in PLCG2, encoding phospholipase Cγ2, causes a dominantly inherited autoinflammatory disease with immunodeficiency.
Qing Zhou, Geun-Shik Lee, Jillian Brady, Shrimati Datta, Matilda Katan, Afzal Sheikh, Marta S Martins, Tom D Bunney, Brian H Santich, Susan Moir,[...]. Am J Hum Genet 2012
195
10

A disintegrin and metalloprotease 17 dynamic interaction sequence, the sweet tooth for the human interleukin 6 receptor.
Stefan Düsterhöft, Katharina Höbel, Mirja Oldefest, Juliane Lokau, Georg H Waetzig, Athena Chalaris, Christoph Garbers, Jürgen Scheller, Stefan Rose-John, Inken Lorenzen,[...]. J Biol Chem 2014
54
18

Whole-exome sequencing identifies tetratricopeptide repeat domain 7A (TTC7A) mutations for combined immunodeficiency with intestinal atresias.
Rui Chen, Silvia Giliani, Gaetana Lanzi, George I Mias, Silvia Lonardi, Kerry Dobbs, John Manis, Hogune Im, Jennifer E Gallagher, Douglas H Phanstiel,[...]. J Allergy Clin Immunol 2013
81
11


Clinical outcome in IL-10- and IL-10 receptor-deficient patients with or without hematopoietic stem cell transplantation.
Karin R Engelhardt, Neil Shah, Intan Faizura-Yeop, Dilara F Kocacik Uygun, Natalie Frede, Aleixo M Muise, Eyal Shteyer, Serkan Filiz, Ronnie Chee, Mamoun Elawad,[...]. J Allergy Clin Immunol 2013
163
9

NADPH oxidase complex and IBD candidate gene studies: identification of a rare variant in NCF2 that results in reduced binding to RAC2.
Aleixo M Muise, Wei Xu, Cong-Hui Guo, Thomas D Walters, Victorien M Wolters, Ramzi Fattouh, Grace Y Lam, Pingzhao Hu, Ryan Murchie, Mary Sherlock,[...]. Gut 2012
122
9

AUTOIMMUNE DISEASE. Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy.
Bernice Lo, Kejian Zhang, Wei Lu, Lixin Zheng, Qian Zhang, Chrysi Kanellopoulou, Yu Zhang, Zhiduo Liu, Jill M Fritz, Rebecca Marsh,[...]. Science 2015
346
9

ADAM-17: the enzyme that does it all.
Monika Gooz. Crit Rev Biochem Mol Biol 2010
267
9

Chronic colitis due to an epithelial barrier defect: the role of kindlin-1 isoforms.
J S Kern, C Herz, E Haan, D Moore, S Nottelmann, T von Lilien, P Greiner, A Schmitt-Graeff, O G Opitz, L Bruckner-Tuderman,[...]. J Pathol 2007
53
16

iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling.
Xiaoping Qing, Yurii Chinenov, Patricia Redecha, Michael Madaio, Joris Jth Roelofs, Gregory Farber, Priya D Issuree, Laura Donlin, David R Mcllwain, Tak W Mak,[...]. J Clin Invest 2018
45
20


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.