A citation-based method for searching scientific literature

Jodi L McBride, Mark R Pitzer, Ryan L Boudreau, Brett Dufour, Theodore Hobbs, Sergio R Ojeda, Beverly L Davidson. Mol Ther 2011
Times Cited: 162







List of co-cited articles
1530 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis.
Holly B Kordasiewicz, Lisa M Stanek, Edward V Wancewicz, Curt Mazur, Melissa M McAlonis, Kimberly A Pytel, Jonathan W Artates, Andreas Weiss, Seng H Cheng, Lamya S Shihabuddin,[...]. Neuron 2012
479
58

Nonallele-specific silencing of mutant and wild-type huntingtin demonstrates therapeutic efficacy in Huntington's disease mice.
Ryan L Boudreau, Jodi L McBride, Inês Martins, Shihao Shen, Yi Xing, Barrie J Carter, Beverly L Davidson. Mol Ther 2009
244
55

Six-month partial suppression of Huntingtin is well tolerated in the adult rhesus striatum.
Richard Grondin, Michael D Kaytor, Yi Ai, Peter T Nelson, Deepak R Thakker, Jennifer Heisel, Marcy R Weatherspoon, Janelle L Blum, Eric N Burright, Zhiming Zhang,[...]. Brain 2012
101
45


Silencing mutant huntingtin by adeno-associated virus-mediated RNA interference ameliorates disease manifestations in the YAC128 mouse model of Huntington's disease.
Lisa M Stanek, Sergio P Sardi, Bryan Mastis, Amy R Richards, Christopher M Treleaven, Tatyana Taksir, Kuma Misra, Seng H Cheng, Lamya S Shihabuddin. Hum Gene Ther 2014
107
41

RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model.
Scott Q Harper, Patrick D Staber, Xiaohua He, Steven L Eliason, Inês H Martins, Qinwen Mao, Linda Yang, Robert M Kotin, Henry L Paulson, Beverly L Davidson. Proc Natl Acad Sci U S A 2005
504
40

Five siRNAs targeting three SNPs may provide therapy for three-quarters of Huntington's disease patients.
Edith L Pfister, Lori Kennington, Juerg Straubhaar, Sujata Wagh, Wanzhou Liu, Marian DiFiglia, Bernhard Landwehrmeyer, Jean-Paul Vonsattel, Phillip D Zamore, Neil Aronin. Curr Biol 2009
186
29

Ablation of huntingtin in adult neurons is nondeleterious but its depletion in young mice causes acute pancreatitis.
Guohao Wang, Xudong Liu, Marta A Gaertig, Shihua Li, Xiao-Jiang Li. Proc Natl Acad Sci U S A 2016
80
36

Targeting Huntingtin Expression in Patients with Huntington's Disease.
Sarah J Tabrizi, Blair R Leavitt, G Bernhard Landwehrmeyer, Edward J Wild, Carsten Saft, Roger A Barker, Nick F Blair, David Craufurd, Josef Priller, Hugh Rickards,[...]. N Engl J Med 2019
298
29

Huntington's disease: from molecular pathogenesis to clinical treatment.
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
933
28

Potent and selective antisense oligonucleotides targeting single-nucleotide polymorphisms in the Huntington disease gene / allele-specific silencing of mutant huntingtin.
Jeffrey B Carroll, Simon C Warby, Amber L Southwell, Crystal N Doty, Sarah Greenlee, Niels Skotte, Gene Hung, C Frank Bennett, Susan M Freier, Michael R Hayden. Mol Ther 2011
184
27

Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: implications for the therapeutic development of RNAi.
Jodi L McBride, Ryan L Boudreau, Scott Q Harper, Patrick D Staber, Alex Mas Monteys, Inâs Martins, Brian L Gilmore, Haim Burstein, Richard W Peluso, Barry Polisky,[...]. Proc Natl Acad Sci U S A 2008
427
27

Sustained effects of nonallele-specific Huntingtin silencing.
Valérie Drouet, Valérie Perrin, Raymonde Hassig, Noëlle Dufour, Gwennaelle Auregan, Sandro Alves, Gilles Bonvento, Emmanuel Brouillet, Ruth Luthi-Carter, Philippe Hantraye,[...]. Ann Neurol 2009
165
26

In vivo evaluation of candidate allele-specific mutant huntingtin gene silencing antisense oligonucleotides.
Amber L Southwell, Niels H Skotte, Holly B Kordasiewicz, Michael E Østergaard, Andrew T Watt, Jeffrey B Carroll, Crystal N Doty, Erika B Villanueva, Eugenia Petoukhov, Kuljeet Vaid,[...]. Mol Ther 2014
91
28

Synthetic zinc finger repressors reduce mutant huntingtin expression in the brain of R6/2 mice.
Mireia Garriga-Canut, Carmen Agustín-Pavón, Frank Herrmann, Aurora Sánchez, Mara Dierssen, Cristina Fillat, Mark Isalan. Proc Natl Acad Sci U S A 2012
101
25

Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes.
J Nasir, S B Floresco, J R O'Kusky, V M Diewert, J M Richman, J Zeisler, A Borowski, J D Marth, A G Phillips, M R Hayden. Cell 1995
595
24


Widespread suppression of huntingtin with convection-enhanced delivery of siRNA.
David K Stiles, Zhiming Zhang, Pei Ge, Brian Nelson, Richard Grondin, Yi Ai, Peter Hardy, Peter T Nelson, Andrei P Guzaev, Mark T Butt,[...]. Exp Neurol 2012
63
36

Design, Characterization, and Lead Selection of Therapeutic miRNAs Targeting Huntingtin for Development of Gene Therapy for Huntington's Disease.
Jana Miniarikova, Ilaria Zanella, Angelina Huseinovic, Tom van der Zon, Evelyn Hanemaaijer, Raygene Martier, Annemart Koornneef, Amber L Southwell, Michael R Hayden, Sander J van Deventer,[...]. Mol Ther Nucleic Acids 2016
64
35

Huntington disease: natural history, biomarkers and prospects for therapeutics.
Christopher A Ross, Elizabeth H Aylward, Edward J Wild, Douglas R Langbehn, Jeffrey D Long, John H Warner, Rachael I Scahill, Blair R Leavitt, Julie C Stout, Jane S Paulsen,[...]. Nat Rev Neurol 2014
554
22

Permanent inactivation of Huntington's disease mutation by personalized allele-specific CRISPR/Cas9.
Jun Wan Shin, Kyung-Hee Kim, Michael J Chao, Ranjit S Atwal, Tammy Gillis, Marcy E MacDonald, James F Gusella, Jong-Min Lee. Hum Mol Genet 2016
134
22

Intrastriatal rAAV-mediated delivery of anti-huntingtin shRNAs induces partial reversal of disease progression in R6/1 Huntington's disease transgenic mice.
Edgardo Rodriguez-Lebron, Eileen M Denovan-Wright, Kevin Nash, Alfred S Lewin, Ronald J Mandel. Mol Ther 2005
212
21

Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits.
M DiFiglia, M Sena-Esteves, K Chase, E Sapp, E Pfister, M Sass, J Yoder, P Reeves, R K Pandey, K G Rajeev,[...]. Proc Natl Acad Sci U S A 2007
298
21

AAV5-miHTT gene therapy demonstrates suppression of mutant huntingtin aggregation and neuronal dysfunction in a rat model of Huntington's disease.
J Miniarikova, V Zimmer, R Martier, C C Brouwers, C Pythoud, K Richetin, M Rey, J Lubelski, M M Evers, S J van Deventer,[...]. Gene Ther 2017
46
45

AAV vector-mediated RNAi of mutant huntingtin expression is neuroprotective in a novel genetic rat model of Huntington's disease.
Nicholas R Franich, Helen L Fitzsimons, Dahna M Fong, Matthias Klugmann, Matthew J During, Deborah Young. Mol Ther 2008
111
20

Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease.
Kirupa Sathasivam, Andreas Neueder, Theresa A Gipson, Christian Landles, Agnesska C Benjamin, Marie K Bondulich, Donna L Smith, Richard L M Faull, Raymund A C Roos, David Howland,[...]. Proc Natl Acad Sci U S A 2013
275
20

AAV5-miHTT Gene Therapy Demonstrates Broad Distribution and Strong Human Mutant Huntingtin Lowering in a Huntington's Disease Minipig Model.
Melvin M Evers, Jana Miniarikova, Stefan Juhas, Astrid Vallès, Bozena Bohuslavova, Jana Juhasova, Helena Kupcova Skalnikova, Petr Vodicka, Ivona Valekova, Cynthia Brouwers,[...]. Mol Ther 2018
74
27

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
19

Single-stranded RNAs use RNAi to potently and allele-selectively inhibit mutant huntingtin expression.
Dongbo Yu, Hannah Pendergraff, Jing Liu, Holly B Kordasiewicz, Don W Cleveland, Eric E Swayze, Walt F Lima, Stanley T Crooke, Thazha P Prakash, David R Corey. Cell 2012
191
19

Intrajugular vein delivery of AAV9-RNAi prevents neuropathological changes and weight loss in Huntington's disease mice.
Brett D Dufour, Catherine A Smith, Randall L Clark, Timothy R Walker, Jodi L McBride. Mol Ther 2014
52
36

CRISPR/Cas9-mediated gene editing ameliorates neurotoxicity in mouse model of Huntington's disease.
Su Yang, Renbao Chang, Huiming Yang, Ting Zhao, Yan Hong, Ha Eun Kong, Xiaobo Sun, Zhaohui Qin, Peng Jin, Shihua Li,[...]. J Clin Invest 2017
170
19


Inactivation of the mouse Huntington's disease gene homolog Hdh.
M P Duyao, A B Auerbach, A Ryan, F Persichetti, G T Barnes, S M McNeil, P Ge, J P Vonsattel, J F Gusella, A L Joyner. Science 1995
500
18

Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS.
Michael E Østergaard, Amber L Southwell, Holly Kordasiewicz, Andrew T Watt, Niels H Skotte, Crystal N Doty, Kuljeet Vaid, Erika B Villanueva, Eric E Swayze, C Frank Bennett,[...]. Nucleic Acids Res 2013
108
18

Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue.
S Zeitlin, J P Liu, D L Chapman, V E Papaioannou, A Efstratiadis. Nat Genet 1995
566
18

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
18

Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients.
Edward J Wild, Roberto Boggio, Douglas Langbehn, Nicola Robertson, Salman Haider, James R C Miller, Henrik Zetterberg, Blair R Leavitt, Rainer Kuhn, Sarah J Tabrizi,[...]. J Clin Invest 2015
128
18

The Biology of Huntingtin.
Frédéric Saudou, Sandrine Humbert. Neuron 2016
388
18

Huntington disease.
Gillian P Bates, Ray Dorsey, James F Gusella, Michael R Hayden, Chris Kay, Blair R Leavitt, Martha Nance, Christopher A Ross, Rachael I Scahill, Ronald Wetzel,[...]. Nat Rev Dis Primers 2015
615
18

An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study.
Timothy M Miller, Alan Pestronk, William David, Jeffrey Rothstein, Ericka Simpson, Stanley H Appel, Patricia L Andres, Katy Mahoney, Peggy Allred, Katie Alexander,[...]. Lancet Neurol 2013
412
17

Allele-specific suppression of mutant huntingtin using antisense oligonucleotides: providing a therapeutic option for all Huntington disease patients.
Niels H Skotte, Amber L Southwell, Michael E Østergaard, Jeffrey B Carroll, Simon C Warby, Crystal N Doty, Eugenia Petoukhov, Kuljeet Vaid, Holly Kordasiewicz, Andrew T Watt,[...]. PLoS One 2014
74
22


Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways.
Dirk Grimm, Konrad L Streetz, Catherine L Jopling, Theresa A Storm, Kusum Pandey, Corrine R Davis, Patricia Marion, Felix Salazar, Mark A Kay. Nature 2006
16

Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease.
Nan Wang, Michelle Gray, Xiao-Hong Lu, Jeffrey P Cantle, Sandra M Holley, Erin Greiner, Xiaofeng Gu, Dyna Shirasaki, Carlos Cepeda, Yuqing Li,[...]. Nat Med 2014
136
16


CRISPR/Cas9 Editing of the Mutant Huntingtin Allele In Vitro and In Vivo.
Alex Mas Monteys, Shauna A Ebanks, Megan S Keiser, Beverly L Davidson. Mol Ther 2017
155
16

The expanded CAG repeat in the huntingtin gene as target for therapeutic RNA modulation throughout the HD mouse brain.
Nicole A Datson, Anchel González-Barriga, Eleni Kourkouta, Rudie Weij, Jeroen van de Giessen, Susan Mulders, Outi Kontkanen, Taneli Heikkinen, Kimmo Lehtimäki, Judith C T van Deutekom. PLoS One 2017
35
45

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease.
Elizabeth J Slow, Jeremy van Raamsdonk, Daniel Rogers, Sarah H Coleman, Rona K Graham, Yu Deng, Rosemary Oh, Nagat Bissada, Sazzad M Hossain, Yu-Zhou Yang,[...]. Hum Mol Genet 2003
587
15

Neuropathological classification of Huntington's disease.
J P Vonsattel, R H Myers, T J Stevens, R J Ferrante, E D Bird, E P Richardson. J Neuropathol Exp Neurol 1985
15

Therapies targeting DNA and RNA in Huntington's disease.
Edward J Wild, Sarah J Tabrizi. Lancet Neurol 2017
142
15


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.