A citation-based method for searching scientific literature

David C Goldstone, Valerie Ennis-Adeniran, Joseph J Hedden, Harriet C T Groom, Gillian I Rice, Evangelos Christodoulou, Philip A Walker, Geoff Kelly, Lesley F Haire, Melvyn W Yap, Luiz Pedro S de Carvalho, Jonathan P Stoye, Yanick J Crow, Ian A Taylor, Michelle Webb. Nature 2011
Times Cited: 551







List of co-cited articles
1200 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx.
Nadine Laguette, Bijan Sobhian, Nicoletta Casartelli, Mathieu Ringeard, Christine Chable-Bessia, Emmanuel Ségéral, Ahmad Yatim, Stéphane Emiliani, Olivier Schwartz, Monsef Benkirane. Nature 2011
65

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates.
Hichem Lahouassa, Waaqo Daddacha, Henning Hofmann, Diana Ayinde, Eric C Logue, Loïc Dragin, Nicolin Bloch, Claire Maudet, Matthieu Bertrand, Thomas Gramberg,[...]. Nat Immunol 2012
562
60

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein.
Kasia Hrecka, Caili Hao, Magda Gierszewska, Selene K Swanson, Malgorzata Kesik-Brodacka, Smita Srivastava, Laurence Florens, Michael P Washburn, Jacek Skowronski. Nature 2011
830
53

SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells.
Hanna-Mari Baldauf, Xiaoyu Pan, Elina Erikson, Sarah Schmidt, Waaqo Daddacha, Manja Burggraf, Kristina Schenkova, Ina Ambiel, Guido Wabnitz, Thomas Gramberg,[...]. Nat Med 2012
413
39


Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response.
Gillian I Rice, Jacquelyn Bond, Aruna Asipu, Rebecca L Brunette, Iain W Manfield, Ian M Carr, Jonathan C Fuller, Richard M Jackson, Teresa Lamb, Tracy A Briggs,[...]. Nat Genet 2009
478
34

Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1.
Alexandra Cribier, Benjamin Descours, Ana Luiza Chaves Valadão, Nadine Laguette, Monsef Benkirane. Cell Rep 2013
265
33

SAMHD1 acts at stalled replication forks to prevent interferon induction.
Flavie Coquel, Maria-Joao Silva, Hervé Técher, Karina Zadorozhny, Sushma Sharma, Jadwiga Nieminuszczy, Clément Mettling, Elodie Dardillac, Antoine Barthe, Anne-Lyne Schmitz,[...]. Nature 2018
144
32

The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation.
Tommy E White, Alberto Brandariz-Nuñez, Jose Carlos Valle-Casuso, Sarah Amie, Laura Anh Nguyen, Baek Kim, Marina Tuzova, Felipe Diaz-Griffero. Cell Host Microbe 2013
221
31

The deoxynucleotide triphosphohydrolase SAMHD1 is a major regulator of DNA precursor pools in mammalian cells.
Elisa Franzolin, Giovanna Pontarin, Chiara Rampazzo, Cristina Miazzi, Paola Ferraro, Elisa Palumbo, Peter Reichard, Vera Bianchi. Proc Natl Acad Sci U S A 2013
154
27

Host factor SAMHD1 restricts DNA viruses in non-dividing myeloid cells.
Joseph A Hollenbaugh, Peter Gee, Jonathon Baker, Michele B Daly, Sarah M Amie, Jessica Tate, Natsumi Kasai, Yuka Kanemura, Dong-Hyun Kim, Brian M Ward,[...]. PLoS Pathog 2013
114
26

The ribonuclease activity of SAMHD1 is required for HIV-1 restriction.
Jeongmin Ryoo, Jongsu Choi, Changhoon Oh, Sungchul Kim, Minji Seo, Seok-Young Kim, Daekwan Seo, Jongkyu Kim, Tommy E White, Alberto Brandariz-Nuñez,[...]. Nat Med 2014
195
25

SAMHD1 restricts herpes simplex virus 1 in macrophages by limiting DNA replication.
Eui Tae Kim, Tommy E White, Alberto Brandariz-Núñez, Felipe Diaz-Griffero, Matthew D Weitzman. J Virol 2013
99
25

SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination.
Waaqo Daddacha, Allyson E Koyen, Amanda J Bastien, PamelaSara E Head, Vishal R Dhere, Geraldine N Nabeta, Erin C Connolly, Erica Werner, Matthew Z Madden, Michele B Daly,[...]. Cell Rep 2017
78
30

Mechanism of allosteric activation of SAMHD1 by dGTP.
Xiaoyun Ji, Ying Wu, Junpeng Yan, Jennifer Mehrens, Haitao Yang, Maria DeLucia, Caili Hao, Angela M Gronenborn, Jacek Skowronski, Jinwoo Ahn,[...]. Nat Struct Mol Biol 2013
97
22

SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells.
Benjamin Descours, Alexandra Cribier, Christine Chable-Bessia, Diana Ayinde, Gillian Rice, Yanick Crow, Ahmad Yatim, Olivier Schwartz, Nadine Laguette, Monsef Benkirane. Retrovirology 2012
245
22

Nuclease activity of the human SAMHD1 protein implicated in the Aicardi-Goutieres syndrome and HIV-1 restriction.
Natalia Beloglazova, Robert Flick, Anatoli Tchigvintsev, Greg Brown, Ana Popovic, Boguslaw Nocek, Alexander F Yakunin. J Biol Chem 2013
159
22

SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage.
Ruth Clifford, Tania Louis, Pauline Robbe, Sam Ackroyd, Adam Burns, Adele T Timbs, Glen Wright Colopy, Helene Dreau, Francois Sigaux, Jean Gabriel Judde,[...]. Blood 2014
140
20

Restriction of diverse retroviruses by SAMHD1.
Thomas Gramberg, Tanja Kahle, Nicolin Bloch, Sabine Wittmann, Erik Müllers, Waaqo Daddacha, Henning Hofmann, Baek Kim, Dirk Lindemann, Nathaniel R Landau. Retrovirology 2013
107
19

Heterozygous colon cancer-associated mutations of SAMHD1 have functional significance.
Matilda Rentoft, Kristoffer Lindell, Phong Tran, Anna Lena Chabes, Robert J Buckland, Danielle L Watt, Lisette Marjavaara, Anna Karin Nilsson, Beatrice Melin, Johan Trygg,[...]. Proc Natl Acad Sci U S A 2016
63
30

SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity.
Jenna M Antonucci, Corine St Gelais, Suresh de Silva, Jacob S Yount, Chenxiang Tang, Xiaoyun Ji, Caitlin Shepard, Yong Xiong, Baek Kim, Li Wu. Nat Med 2016
55
34

Structural basis of cellular dNTP regulation by SAMHD1.
Xiaoyun Ji, Chenxiang Tang, Qi Zhao, Wei Wang, Yong Xiong. Proc Natl Acad Sci U S A 2014
79
24

Inhibition of Hepatitis B virus replication by SAMHD1.
Zhangming Chen, Mengying Zhu, Xiang Pan, Yongji Zhu, Hai Yan, Tongcui Jiang, Yujun Shen, Xiaowan Dong, Nan Zheng, Jinsen Lu,[...]. Biochem Biophys Res Commun 2014
58
32

Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac.
Alberto Brandariz-Nuñez, Jose Carlos Valle-Casuso, Tommy E White, Nadine Laguette, Monsef Benkirane, Jurgen Brojatsch, Felipe Diaz-Griffero. Retrovirology 2012
114
19

Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response.
Rayk Behrendt, Tina Schumann, Alexander Gerbaulet, Laura A Nguyen, Nadja Schubert, Dimitra Alexopoulou, Ursula Berka, Stefan Lienenklaus, Katrin Peschke, Kathrin Gibbert,[...]. Cell Rep 2013
114
17

Contribution of SAM and HD domains to retroviral restriction mediated by human SAMHD1.
Tommy E White, Alberto Brandariz-Nuñez, Jose Carlos Valle-Casuso, Sarah Amie, Laura Nguyen, Baek Kim, Jurgen Brojatsch, Felipe Diaz-Griffero. Virology 2013
104
17

HIV/simian immunodeficiency virus (SIV) accessory virulence factor Vpx loads the host cell restriction factor SAMHD1 onto the E3 ubiquitin ligase complex CRL4DCAF1.
Jinwoo Ahn, Caili Hao, Junpeng Yan, Maria DeLucia, Jennifer Mehrens, Chuanping Wang, Angela M Gronenborn, Jacek Skowronski. J Biol Chem 2012
133
17

SAMHD1-deficient CD14+ cells from individuals with Aicardi-Goutières syndrome are highly susceptible to HIV-1 infection.
André Berger, Andreas F R Sommer, Jenny Zwarg, Matthias Hamdorf, Karin Welzel, Nicole Esly, Sylvia Panitz, Andreas Reuter, Irene Ramos, Asavari Jatiani,[...]. PLoS Pathog 2011
191
16

The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx.
Efrem S Lim, Oliver I Fregoso, Connor O McCoy, Frederick A Matsen, Harmit S Malik, Michael Emerman. Cell Host Microbe 2012
197
16

Restrictive influence of SAMHD1 on Hepatitis B Virus life cycle.
Andreas F R Sommer, Lise Rivière, Bingqian Qu, Kerstin Schott, Maximilian Riess, Yi Ni, Caitlin Shepard, Esther Schnellbächer, Malin Finkernagel, Kiyoshi Himmelsbach,[...]. Sci Rep 2016
42
38

Host restriction factor SAMHD1 limits human T cell leukemia virus type 1 infection of monocytes via STING-mediated apoptosis.
Alexandre Sze, S Mehdi Belgnaoui, David Olagnier, Rongtuan Lin, John Hiscott, Julien van Grevenynghe. Cell Host Microbe 2013
115
15

SAMHD1-dependent retroviral control and escape in mice.
Jan Rehwinkel, Jonathan Maelfait, Anne Bridgeman, Rachel Rigby, Bruce Hayward, Rachel A Liberatore, Paul D Bieniasz, Greg J Towers, Luis F Moita, Yanick J Crow,[...]. EMBO J 2013
115
15

CyclinA2-Cyclin-dependent Kinase Regulates SAMHD1 Protein Phosphohydrolase Domain.
Junpeng Yan, Caili Hao, Maria DeLucia, Selene Swanson, Laurence Florens, Michael P Washburn, Jinwoo Ahn, Jacek Skowronski. J Biol Chem 2015
63
23

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu.
Stuart J D Neil, Trinity Zang, Paul D Bieniasz. Nature 2008
15

Tetramerization of SAMHD1 is required for biological activity and inhibition of HIV infection.
Junpeng Yan, Sarabpreet Kaur, Maria DeLucia, Caili Hao, Jennifer Mehrens, Chuanping Wang, Marcin Golczak, Krzysztof Palczewski, Angela M Gronenborn, Jinwoo Ahn,[...]. J Biol Chem 2013
108
15


Modulation of LINE-1 and Alu/SVA retrotransposition by Aicardi-Goutières syndrome-related SAMHD1.
Ke Zhao, Juan Du, Xue Han, John L Goodier, Peng Li, Xiaohong Zhou, Wei Wei, Sean L Evans, Linzhang Li, Wenyan Zhang,[...]. Cell Rep 2013
136
14


SAMHD1 restricts HIV-1 infection in dendritic cells (DCs) by dNTP depletion, but its expression in DCs and primary CD4+ T-lymphocytes cannot be upregulated by interferons.
Corine St Gelais, Suresh de Silva, Sarah M Amie, Christopher M Coleman, Heather Hoy, Joseph A Hollenbaugh, Baek Kim, Li Wu. Retrovirology 2012
140
14

The Vpx lentiviral accessory protein targets SAMHD1 for degradation in the nucleus.
Henning Hofmann, Eric C Logue, Nicolin Bloch, Waaqo Daddacha, Sylvie B Polsky, Megan L Schultz, Baek Kim, Nathaniel R Landau. J Virol 2012
93
15

Dephosphorylation of the HIV-1 restriction factor SAMHD1 is mediated by PP2A-B55α holoenzymes during mitotic exit.
Kerstin Schott, Nina V Fuchs, Rita Derua, Bijan Mahboubi, Esther Schnellbächer, Janna Seifried, Christiane Tondera, Heike Schmitz, Caitlin Shepard, Alberto Brandariz-Nuñez,[...]. Nat Commun 2018
26
53

Restriction of virus infection but not catalytic dNTPase activity is regulated by phosphorylation of SAMHD1.
Sarah Welbourn, Sucharita M Dutta, O John Semmes, Klaus Strebel. J Virol 2013
117
14

Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction.
Laurence H Arnold, Harriet C T Groom, Simone Kunzelmann, David Schwefel, Sarah J Caswell, Paula Ordonez, Melanie C Mann, Sabrina Rueschenbaum, David C Goldstone, Simon Pennell,[...]. PLoS Pathog 2015
68
20

Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies.
Nikolas Herold, Sean G Rudd, Linda Ljungblad, Kumar Sanjiv, Ida Hed Myrberg, Cynthia B J Paulin, Yaser Heshmati, Anna Hagenkort, Juliane Kutzner, Brent D G Page,[...]. Nat Med 2017
65
20

SAMHD1 is a nucleic-acid binding protein that is mislocalized due to aicardi-goutières syndrome-associated mutations.
Adriana Goncalves, Evren Karayel, Gillian I Rice, Keiryn L Bennett, Yanick J Crow, Giulio Superti-Furga, Tilmann Bürckstümmer. Hum Mutat 2012
104
13

SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways.
Shuliang Chen, Serena Bonifati, Zhihua Qin, Corine St Gelais, Karthik M Kodigepalli, Bradley S Barrett, Sun Hee Kim, Jenna M Antonucci, Katherine J Ladner, Olga Buzovetsky,[...]. Proc Natl Acad Sci U S A 2018
44
29

Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses.
Daxing Gao, Jiaxi Wu, You-Tong Wu, Fenghe Du, Chukwuemika Aroh, Nan Yan, Lijun Sun, Zhijian J Chen. Science 2013
595
13

SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia.
Constanze Schneider, Thomas Oellerich, Hanna-Mari Baldauf, Sarah-Marie Schwarz, Dominique Thomas, Robert Flick, Hanibal Bohnenberger, Lars Kaderali, Lena Stegmann, Anjali Cremer,[...]. Nat Med 2017
61
21

SAMHD1 is a single-stranded nucleic acid binding protein with no active site-associated nuclease activity.
Kyle J Seamon, Zhiqiang Sun, Luda S Shlyakhtenko, Yuri L Lyubchenko, James T Stivers. Nucleic Acids Res 2015
82
15

Effects of T592 phosphomimetic mutations on tetramer stability and dNTPase activity of SAMHD1 can not explain the retroviral restriction defect.
Akash Bhattacharya, Zhonghua Wang, Tommy White, Cindy Buffone, Laura A Nguyen, Caitlin N Shepard, Baek Kim, Borries Demeler, Felipe Diaz-Griffero, Dmitri N Ivanov. Sci Rep 2016
38
34


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.