Benjamin D Auerbach, Emily K Osterweil, Mark F Bear. Nature 2011
Times Cited: 419
Times Cited: 419
Times Cited
Times Co-cited
Similarity
Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis.
Dan Ehninger, Sangyeul Han, Carrie Shilyansky, Yu Zhou, Weidong Li, David J Kwiatkowski, Vijaya Ramesh, Alcino J Silva. Nat Med 2008
Dan Ehninger, Sangyeul Han, Carrie Shilyansky, Yu Zhou, Weidong Li, David J Kwiatkowski, Vijaya Ramesh, Alcino J Silva. Nat Med 2008
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Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits.
Guomei Tang, Kathryn Gudsnuk, Sheng-Han Kuo, Marisa L Cotrina, Gorazd Rosoklija, Alexander Sosunov, Mark S Sonders, Ellen Kanter, Candace Castagna, Ai Yamamoto,[...]. Neuron 2014
Guomei Tang, Kathryn Gudsnuk, Sheng-Han Kuo, Marisa L Cotrina, Gorazd Rosoklija, Alexander Sosunov, Mark S Sonders, Ellen Kanter, Candace Castagna, Ai Yamamoto,[...]. Neuron 2014
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Altered synaptic plasticity in a mouse model of fragile X mental retardation.
Kimberly M Huber, Sean M Gallagher, Stephen T Warren, Mark F Bear. Proc Natl Acad Sci U S A 2002
Kimberly M Huber, Sean M Gallagher, Stephen T Warren, Mark F Bear. Proc Natl Acad Sci U S A 2002
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Exaggerated translation causes synaptic and behavioural aberrations associated with autism.
Emanuela Santini, Thu N Huynh, Andrew F MacAskill, Adam G Carter, Philippe Pierre, Davide Ruggero, Hanoch Kaphzan, Eric Klann. Nature 2013
Emanuela Santini, Thu N Huynh, Andrew F MacAskill, Adam G Carter, Philippe Pierre, Davide Ruggero, Hanoch Kaphzan, Eric Klann. Nature 2013
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Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2.
Sohail F Tavazoie, Veronica A Alvarez, Dennis A Ridenour, David J Kwiatkowski, Bernardo L Sabatini. Nat Neurosci 2005
Sohail F Tavazoie, Veronica A Alvarez, Dennis A Ridenour, David J Kwiatkowski, Bernardo L Sabatini. Nat Neurosci 2005
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Synaptic, transcriptional and chromatin genes disrupted in autism.
Silvia De Rubeis, Xin He, Arthur P Goldberg, Christopher S Poultney, Kaitlin Samocha, A Erucment Cicek, Yan Kou, Li Liu, Menachem Fromer, Susan Walker,[...]. Nature 2014
Silvia De Rubeis, Xin He, Arthur P Goldberg, Christopher S Poultney, Kaitlin Samocha, A Erucment Cicek, Yan Kou, Li Liu, Menachem Fromer, Susan Walker,[...]. Nature 2014
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Dysregulation of mTOR signaling in fragile X syndrome.
Ali Sharma, Charles A Hoeffer, Yukihiro Takayasu, Takahiro Miyawaki, Sean M McBride, Eric Klann, R Suzanne Zukin. J Neurosci 2010
Ali Sharma, Charles A Hoeffer, Yukihiro Takayasu, Takahiro Miyawaki, Sean M McBride, Eric Klann, R Suzanne Zukin. J Neurosci 2010
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Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice.
Peter T Tsai, Court Hull, YunXiang Chu, Emily Greene-Colozzi, Abbey R Sadowski, Jarrett M Leech, Jason Steinberg, Jacqueline N Crawley, Wade G Regehr, Mustafa Sahin. Nature 2012
Peter T Tsai, Court Hull, YunXiang Chu, Emily Greene-Colozzi, Abbey R Sadowski, Jarrett M Leech, Jason Steinberg, Jacqueline N Crawley, Wade G Regehr, Mustafa Sahin. Nature 2012
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Shank3 mutant mice display autistic-like behaviours and striatal dysfunction.
João Peça, Cátia Feliciano, Jonathan T Ting, Wenting Wang, Michael F Wells, Talaignair N Venkatraman, Christopher D Lascola, Zhanyan Fu, Guoping Feng. Nature 2011
João Peça, Cátia Feliciano, Jonathan T Ting, Wenting Wang, Michael F Wells, Talaignair N Venkatraman, Christopher D Lascola, Zhanyan Fu, Guoping Feng. Nature 2011
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The mGluR theory of fragile X mental retardation.
Mark F Bear, Kimberly M Huber, Stephen T Warren. Trends Neurosci 2004
Mark F Bear, Kimberly M Huber, Stephen T Warren. Trends Neurosci 2004
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Excitatory/inhibitory synaptic imbalance leads to hippocampal hyperexcitability in mouse models of tuberous sclerosis.
Helen S Bateup, Caroline A Johnson, Cassandra L Denefrio, Jessica L Saulnier, Karl Kornacker, Bernardo L Sabatini. Neuron 2013
Helen S Bateup, Caroline A Johnson, Cassandra L Denefrio, Jessica L Saulnier, Karl Kornacker, Bernardo L Sabatini. Neuron 2013
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FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism.
Jennifer C Darnell, Sarah J Van Driesche, Chaolin Zhang, Ka Ying Sharon Hung, Aldo Mele, Claire E Fraser, Elizabeth F Stone, Cynthia Chen, John J Fak, Sung Wook Chi,[...]. Cell 2011
Jennifer C Darnell, Sarah J Van Driesche, Chaolin Zhang, Ka Ying Sharon Hung, Aldo Mele, Claire E Fraser, Elizabeth F Stone, Cynthia Chen, John J Fak, Sung Wook Chi,[...]. Cell 2011
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The contribution of de novo coding mutations to autism spectrum disorder.
Ivan Iossifov, Brian J O'Roak, Stephan J Sanders, Michael Ronemus, Niklas Krumm, Dan Levy, Holly A Stessman, Kali T Witherspoon, Laura Vives, Karynne E Patterson,[...]. Nature 2014
Ivan Iossifov, Brian J O'Roak, Stephan J Sanders, Michael Ronemus, Niklas Krumm, Dan Levy, Holly A Stessman, Kali T Witherspoon, Laura Vives, Karynne E Patterson,[...]. Nature 2014
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Loss of Tsc1 in vivo impairs hippocampal mGluR-LTD and increases excitatory synaptic function.
Helen S Bateup, Kevin T Takasaki, Jessica L Saulnier, Cassandra L Denefrio, Bernardo L Sabatini. J Neurosci 2011
Helen S Bateup, Kevin T Takasaki, Jessica L Saulnier, Cassandra L Denefrio, Bernardo L Sabatini. J Neurosci 2011
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Autism-related deficits via dysregulated eIF4E-dependent translational control.
Christos G Gkogkas, Arkady Khoutorsky, Israeli Ran, Emmanouil Rampakakis, Tatiana Nevarko, Daniel B Weatherill, Cristina Vasuta, Stephanie Yee, Morgan Truitt, Paul Dallaire,[...]. Nature 2013
Christos G Gkogkas, Arkady Khoutorsky, Israeli Ran, Emmanouil Rampakakis, Tatiana Nevarko, Daniel B Weatherill, Cristina Vasuta, Stephanie Yee, Morgan Truitt, Paul Dallaire,[...]. Nature 2013
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Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits.
Olga Peñagarikano, Brett S Abrahams, Edward I Herman, Kellen D Winden, Amos Gdalyahu, Hongmei Dong, Lisa I Sonnenblick, Robin Gruver, Joel Almajano, Anatol Bragin,[...]. Cell 2011
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From the genetic architecture to synaptic plasticity in autism spectrum disorder.
Thomas Bourgeron. Nat Rev Neurosci 2015
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Pten regulates neuronal arborization and social interaction in mice.
Chang-Hyuk Kwon, Bryan W Luikart, Craig M Powell, Jing Zhou, Sharon A Matheny, Wei Zhang, Yanjiao Li, Suzanne J Baker, Luis F Parada. Neuron 2006
Chang-Hyuk Kwon, Bryan W Luikart, Craig M Powell, Jing Zhou, Sharon A Matheny, Wei Zhang, Yanjiao Li, Suzanne J Baker, Luis F Parada. Neuron 2006
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Advancing the understanding of autism disease mechanisms through genetics.
Luis de la Torre-Ubieta, Hyejung Won, Jason L Stein, Daniel H Geschwind. Nat Med 2016
Luis de la Torre-Ubieta, Hyejung Won, Jason L Stein, Daniel H Geschwind. Nat Med 2016
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Model of autism: increased ratio of excitation/inhibition in key neural systems.
J L R Rubenstein, M M Merzenich. Genes Brain Behav 2003
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Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes.
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Hsiao-Tuan Chao, Hongmei Chen, Rodney C Samaco, Mingshan Xue, Maria Chahrour, Jong Yoo, Jeffrey L Neul, Shiaoching Gong, Hui-Chen Lu, Nathaniel Heintz,[...]. Nature 2010
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Neurological and neuropsychiatric aspects of tuberous sclerosis complex.
Paolo Curatolo, Romina Moavero, Petrus J de Vries. Lancet Neurol 2015
Paolo Curatolo, Romina Moavero, Petrus J de Vries. Lancet Neurol 2015
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Activity-dependent neuronal signalling and autism spectrum disorder.
Daniel H Ebert, Michael E Greenberg. Nature 2013
Daniel H Ebert, Michael E Greenberg. Nature 2013
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Rapamycin reverses impaired social interaction in mouse models of tuberous sclerosis complex.
Atsushi Sato, Shinya Kasai, Toshiyuki Kobayashi, Yukio Takamatsu, Okio Hino, Kazutaka Ikeda, Masashi Mizuguchi. Nat Commun 2012
Atsushi Sato, Shinya Kasai, Toshiyuki Kobayashi, Yukio Takamatsu, Okio Hino, Kazutaka Ikeda, Masashi Mizuguchi. Nat Commun 2012
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Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice.
Aubin Michalon, Michael Sidorov, Theresa M Ballard, Laurence Ozmen, Will Spooren, Joseph G Wettstein, Georg Jaeschke, Mark F Bear, Lothar Lindemann. Neuron 2012
Aubin Michalon, Michael Sidorov, Theresa M Ballard, Laurence Ozmen, Will Spooren, Joseph G Wettstein, Georg Jaeschke, Mark F Bear, Lothar Lindemann. Neuron 2012
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Synaptic dysfunction in neurodevelopmental disorders associated with autism and intellectual disabilities.
Huda Y Zoghbi, Mark F Bear. Cold Spring Harb Perspect Biol 2012
Huda Y Zoghbi, Mark F Bear. Cold Spring Harb Perspect Biol 2012
12
Cognitive deficits in Tsc1+/- mice in the absence of cerebral lesions and seizures.
Susanna M I Goorden, Geeske M van Woerden, Louise van der Weerd, Jeremy P Cheadle, Ype Elgersma. Ann Neurol 2007
Susanna M I Goorden, Geeske M van Woerden, Louise van der Weerd, Jeremy P Cheadle, Ype Elgersma. Ann Neurol 2007
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Excitatory/Inhibitory Balance and Circuit Homeostasis in Autism Spectrum Disorders.
Sacha B Nelson, Vera Valakh. Neuron 2015
Sacha B Nelson, Vera Valakh. Neuron 2015
12
Dendritic spine pathology in neuropsychiatric disorders.
Peter Penzes, Michael E Cahill, Kelly A Jones, Jon-Eric VanLeeuwen, Kevin M Woolfrey. Nat Neurosci 2011
Peter Penzes, Michael E Cahill, Kelly A Jones, Jon-Eric VanLeeuwen, Kevin M Woolfrey. Nat Neurosci 2011
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Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations.
Brian J O'Roak, Laura Vives, Santhosh Girirajan, Emre Karakoc, Niklas Krumm, Bradley P Coe, Roie Levy, Arthur Ko, Choli Lee, Joshua D Smith,[...]. Nature 2012
Brian J O'Roak, Laura Vives, Santhosh Girirajan, Emre Karakoc, Niklas Krumm, Bradley P Coe, Roie Levy, Arthur Ko, Choli Lee, Joshua D Smith,[...]. Nature 2012
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Dysregulation of Mammalian Target of Rapamycin Signaling in Mouse Models of Autism.
Kimberly M Huber, Eric Klann, Mauro Costa-Mattioli, R Suzanne Zukin. J Neurosci 2015
Kimberly M Huber, Eric Klann, Mauro Costa-Mattioli, R Suzanne Zukin. J Neurosci 2015
11
Shared synaptic pathophysiology in syndromic and nonsyndromic rodent models of autism.
Stéphane J Baudouin, Julien Gaudias, Stefan Gerharz, Laetitia Hatstatt, Kuikui Zhou, Pradeep Punnakkal, Kenji F Tanaka, Will Spooren, Rene Hen, Chris I De Zeeuw,[...]. Science 2012
Stéphane J Baudouin, Julien Gaudias, Stefan Gerharz, Laetitia Hatstatt, Kuikui Zhou, Pradeep Punnakkal, Kenji F Tanaka, Will Spooren, Rene Hen, Chris I De Zeeuw,[...]. Science 2012
11
11
A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival.
Lynsey Meikle, Delia M Talos, Hiroaki Onda, Kristen Pollizzi, Alexander Rotenberg, Mustafa Sahin, Frances E Jensen, David J Kwiatkowski. J Neurosci 2007
Lynsey Meikle, Delia M Talos, Hiroaki Onda, Kristen Pollizzi, Alexander Rotenberg, Mustafa Sahin, Frances E Jensen, David J Kwiatkowski. J Neurosci 2007
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De novo gene disruptions in children on the autistic spectrum.
Ivan Iossifov, Michael Ronemus, Dan Levy, Zihua Wang, Inessa Hakker, Julie Rosenbaum, Boris Yamrom, Yoon-Ha Lee, Giuseppe Narzisi, Anthony Leotta,[...]. Neuron 2012
Ivan Iossifov, Michael Ronemus, Dan Levy, Zihua Wang, Inessa Hakker, Julie Rosenbaum, Boris Yamrom, Yoon-Ha Lee, Giuseppe Narzisi, Anthony Leotta,[...]. Neuron 2012
11
Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism.
Xiaoming Wang, Alexandra L Bey, Brittany M Katz, Alexandra Badea, Namsoo Kim, Lisa K David, Lara J Duffney, Sunil Kumar, Stephen D Mague, Samuel W Hulbert,[...]. Nat Commun 2016
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11
Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism.
F Kyle Satterstrom, Jack A Kosmicki, Jiebiao Wang, Michael S Breen, Silvia De Rubeis, Joon-Yong An, Minshi Peng, Ryan Collins, Jakob Grove, Lambertus Klei,[...]. Cell 2020
F Kyle Satterstrom, Jack A Kosmicki, Jiebiao Wang, Michael S Breen, Silvia De Rubeis, Joon-Yong An, Minshi Peng, Ryan Collins, Jakob Grove, Lambertus Klei,[...]. Cell 2020
11
Translational control of long-lasting synaptic plasticity and memory.
Mauro Costa-Mattioli, Wayne S Sossin, Eric Klann, Nahum Sonenberg. Neuron 2009
Mauro Costa-Mattioli, Wayne S Sossin, Eric Klann, Nahum Sonenberg. Neuron 2009
10
Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome.
Jennifer A Ronesi, Katie A Collins, Seth A Hays, Nien-Pei Tsai, Weirui Guo, Shari G Birnbaum, Jia-Hua Hu, Paul F Worley, Jay R Gibson, Kimberly M Huber. Nat Neurosci 2012
Jennifer A Ronesi, Katie A Collins, Seth A Hays, Nien-Pei Tsai, Weirui Guo, Shari G Birnbaum, Jia-Hua Hu, Paul F Worley, Jay R Gibson, Kimberly M Huber. Nat Neurosci 2012
10
Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders.
Jeffrey J Hutsler, Hong Zhang. Brain Res 2010
Jeffrey J Hutsler, Hong Zhang. Brain Res 2010
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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.
Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan. Nat Cell Biol 2011
Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan. Nat Cell Biol 2011
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The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP.
Ilaria Napoli, Valentina Mercaldo, Pietro Pilo Boyl, Boris Eleuteri, Francesca Zalfa, Silvia De Rubeis, Daniele Di Marino, Evita Mohr, Marzia Massimi, Mattia Falconi,[...]. Cell 2008
Ilaria Napoli, Valentina Mercaldo, Pietro Pilo Boyl, Boris Eleuteri, Francesca Zalfa, Silvia De Rubeis, Daniele Di Marino, Evita Mohr, Marzia Massimi, Mattia Falconi,[...]. Cell 2008
10
Dysregulation and restoration of translational homeostasis in fragile X syndrome.
Joel D Richter, Gary J Bassell, Eric Klann. Nat Rev Neurosci 2015
Joel D Richter, Gary J Bassell, Eric Klann. Nat Rev Neurosci 2015
10
Convergence of Hippocampal Pathophysiology in Syngap+/- and Fmr1-/y Mice.
Stephanie A Barnes, Lasani S Wijetunge, Adam D Jackson, Danai Katsanevaki, Emily K Osterweil, Noboru H Komiyama, Seth G N Grant, Mark F Bear, U Valentin Nägerl, Peter C Kind,[...]. J Neurosci 2015
Stephanie A Barnes, Lasani S Wijetunge, Adam D Jackson, Danai Katsanevaki, Emily K Osterweil, Noboru H Komiyama, Seth G N Grant, Mark F Bear, U Valentin Nägerl, Peter C Kind,[...]. J Neurosci 2015
20
Deregulation of EIF4E: a novel mechanism for autism.
M Neves-Pereira, B Müller, D Massie, J H G Williams, P C M O'Brien, A Hughes, S-B Shen, David St Clair, Z Miedzybrodzka. J Med Genet 2009
M Neves-Pereira, B Müller, D Massie, J H G Williams, P C M O'Brien, A Hughes, S-B Shen, David St Clair, Z Miedzybrodzka. J Med Genet 2009
10
Most genetic risk for autism resides with common variation.
Trent Gaugler, Lambertus Klei, Stephan J Sanders, Corneliu A Bodea, Arthur P Goldberg, Ann B Lee, Milind Mahajan, Dina Manaa, Yudi Pawitan, Jennifer Reichert,[...]. Nat Genet 2014
Trent Gaugler, Lambertus Klei, Stephan J Sanders, Corneliu A Bodea, Arthur P Goldberg, Ann B Lee, Milind Mahajan, Dina Manaa, Yudi Pawitan, Jennifer Reichert,[...]. Nat Genet 2014
10
Correction of fragile X syndrome in mice.
Gül Dölen, Emily Osterweil, B S Shankaranarayana Rao, Gordon B Smith, Benjamin D Auerbach, Sumantra Chattarji, Mark F Bear. Neuron 2007
Gül Dölen, Emily Osterweil, B S Shankaranarayana Rao, Gordon B Smith, Benjamin D Auerbach, Sumantra Chattarji, Mark F Bear. Neuron 2007
10
CYFIP1 coordinates mRNA translation and cytoskeleton remodeling to ensure proper dendritic spine formation.
Silvia De Rubeis, Emanuela Pasciuto, Ka Wan Li, Esperanza Fernández, Daniele Di Marino, Andrea Buzzi, Linnaea E Ostroff, Eric Klann, Fried J T Zwartkruis, Noboru H Komiyama,[...]. Neuron 2013
Silvia De Rubeis, Emanuela Pasciuto, Ka Wan Li, Esperanza Fernández, Daniele Di Marino, Andrea Buzzi, Linnaea E Ostroff, Eric Klann, Fried J T Zwartkruis, Noboru H Komiyama,[...]. Neuron 2013
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.