A citation-based method for searching scientific literature

Benoit Viollet, Bruno Guigas, Nieves Sanz Garcia, Jocelyne Leclerc, Marc Foretz, Fabrizio Andreelli. Clin Sci (Lond) 2012
Times Cited: 1001







List of co-cited articles
665 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Role of AMP-activated protein kinase in mechanism of metformin action.
G Zhou, R Myers, Y Li, Y Chen, X Shen, J Fenyk-Melody, M Wu, J Ventre, T Doebber, N Fujii,[...]. J Clin Invest 2001
19

The mechanisms of action of metformin.
Graham Rena, D Grahame Hardie, Ewan R Pearson. Diabetologia 2017
751
18

Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase.
Anila K Madiraju, Derek M Erion, Yasmeen Rahimi, Xian-Man Zhang, Demetrios T Braddock, Ronald A Albright, Brett J Prigaro, John L Wood, Sanjay Bhanot, Michael J MacDonald,[...]. Nature 2014
708
9


Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.
M Y El-Mir, V Nogueira, E Fontaine, N Avéret, M Rigoulet, X Leverve. J Biol Chem 2000
955
9

Clinical pharmacokinetics of metformin.
Garry G Graham, Jeroen Punt, Manit Arora, Richard O Day, Matthew P Doogue, Janna K Duong, Timothy J Furlong, Jerry R Greenfield, Louise C Greenup, Carl M Kirkpatrick,[...]. Clin Pharmacokinet 2011
628
9

Metformin and reduced risk of cancer in diabetic patients.
Josie M M Evans, Louise A Donnelly, Alistair M Emslie-Smith, Dario R Alessi, Andrew D Morris. BMJ 2005
8

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.
Marc Foretz, Sophie Hébrard, Jocelyne Leclerc, Elham Zarrinpashneh, Maud Soty, Gilles Mithieux, Kei Sakamoto, Fabrizio Andreelli, Benoit Viollet. J Clin Invest 2010
835
8

Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria.
Hannah R Bridges, Andrew J Y Jones, Michael N Pollak, Judy Hirst. Biochem J 2014
384
8

Metformin: from mechanisms of action to therapies.
Marc Foretz, Bruno Guigas, Luc Bertrand, Michael Pollak, Benoit Viollet. Cell Metab 2014
661
8

Metformin action: concentrations matter.
Ling He, Fredric E Wondisford. Cell Metab 2015
239
8

Metformin: a review of its potential indications.
Yi-Wei Wang, Si-Jia He, Xiao Feng, Jin Cheng, Yun-Tao Luo, Ling Tian, Qian Huang. Drug Des Devel Ther 2017
108
7

AMPK: a nutrient and energy sensor that maintains energy homeostasis.
D Grahame Hardie, Fiona A Ross, Simon A Hawley. Nat Rev Mol Cell Biol 2012
7

Metformin and the gastrointestinal tract.
Laura J McCreight, Clifford J Bailey, Ewan R Pearson. Diabetologia 2016
293
6

Metformin, the aspirin of the 21st century: its role in gestational diabetes mellitus, prevention of preeclampsia and cancer, and the promotion of longevity.
Roberto Romero, Offer Erez, Maik Hüttemann, Eli Maymon, Bogdan Panaitescu, Agustin Conde-Agudelo, Percy Pacora, Bo Hyun Yoon, Lawrence I Grossman. Am J Obstet Gynecol 2017
114
6

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug.
Hao Wu, Eduardo Esteve, Valentina Tremaroli, Muhammad Tanweer Khan, Robert Caesar, Louise Mannerås-Holm, Marcus Ståhlman, Lisa M Olsson, Matteo Serino, Mercè Planas-Fèlix,[...]. Nat Med 2017
630
6

Metformin--mode of action and clinical implications for diabetes and cancer.
Ida Pernicova, Márta Korbonits. Nat Rev Endocrinol 2014
645
6

Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner.
Adem Kalender, Anand Selvaraj, So Young Kim, Pawan Gulati, Sophie Brûlé, Benoit Viollet, Bruce E Kemp, Nabeel Bardeesy, Patrick Dennis, John J Schlager,[...]. Cell Metab 2010
587
6

Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action.
Yan Shu, Steven A Sheardown, Chaline Brown, Ryan P Owen, Shuzhong Zhang, Richard A Castro, Alexandra G Ianculescu, Lin Yue, Joan C Lo, Esteban G Burchard,[...]. J Clin Invest 2007
613
6

Metformin: historical overview.
Clifford J Bailey. Diabetologia 2017
291
6

Cellular and Molecular Mechanisms of Metformin Action.
Traci E LaMoia, Gerald I Shulman. Endocr Rev 2021
52
11

Metformin in cancer prevention and therapy.
Jacek Kasznicki, Agnieszka Sliwinska, Józef Drzewoski. Ann Transl Med 2014
231
5

AMPK: guardian of metabolism and mitochondrial homeostasis.
Sébastien Herzig, Reuben J Shaw. Nat Rev Mol Cell Biol 2018
5

Role of Mitochondria in the Mechanism(s) of Action of Metformin.
Guillaume Vial, Dominique Detaille, Bruno Guigas. Front Endocrinol (Lausanne) 2019
100
5


The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level.
I Ben Sahra, K Laurent, A Loubat, S Giorgetti-Peraldi, P Colosetti, P Auberger, J F Tanti, Y Le Marchand-Brustel, F Bost. Oncogene 2008
652
5

Metformin: an old but still the best treatment for type 2 diabetes.
Lilian Beatriz Aguayo Rojas, Marilia Brito Gomes. Diabetol Metab Syndr 2013
273
5

Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP.
Russell A Miller, Qingwei Chu, Jianxin Xie, Marc Foretz, Benoit Viollet, Morris J Birnbaum. Nature 2013
526
5


Metformin: Mechanisms in Human Obesity and Weight Loss.
Armen Yerevanian, Alexander A Soukas. Curr Obes Rep 2019
65
7

An increase in the Akkermansia spp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice.
Na-Ri Shin, June-Chul Lee, Hae-Youn Lee, Min-Soo Kim, Tae Woong Whon, Myung-Shik Lee, Jin-Woo Bae. Gut 2014
835
5

Metformin activates AMP kinase through inhibition of AMP deaminase.
Jiangyong Ouyang, Rahulkumar A Parakhia, Raymond S Ochs. J Biol Chem 2011
164
5

Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo.
Anila K Madiraju, Yang Qiu, Rachel J Perry, Yasmeen Rahimi, Xian-Man Zhang, Dongyan Zhang, João-Paulo G Camporez, Gary W Cline, Gina M Butrico, Bruce E Kemp,[...]. Nat Med 2018
111
5

Benefits of Metformin in Attenuating the Hallmarks of Aging.
Ameya S Kulkarni, Sriram Gubbi, Nir Barzilai. Cell Metab 2020
120
5

Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1.
Isaam Ben Sahra, Claire Regazzetti, Guillaume Robert, Kathiane Laurent, Yannick Le Marchand-Brustel, Patrick Auberger, Jean-François Tanti, Sophie Giorgetti-Peraldi, Frédéric Bost. Cancer Res 2011
444
5


Metformin Is a Direct SIRT1-Activating Compound: Computational Modeling and Experimental Validation.
Elisabet Cuyàs, Sara Verdura, Laura Llorach-Parés, Salvador Fernández-Arroyo, Jorge Joven, Begoña Martin-Castillo, Joaquim Bosch-Barrera, Joan Brunet, Alfons Nonell-Canals, Melchor Sanchez-Martinez,[...]. Front Endocrinol (Lausanne) 2018
62
8

An intracellular modulation of free radical production could contribute to the beneficial effects of metformin towards oxidative stress.
D Bonnefont-Rousselot, B Raji, S Walrand, M Gardès-Albert, D Jore, A Legrand, J Peynet, M P Vasson. Metabolism 2003
131
4

Metformin reduces endogenous reactive oxygen species and associated DNA damage.
Carolyn Algire, Olga Moiseeva, Xavier Deschênes-Simard, Lilian Amrein, Luca Petruccelli, Elena Birman, Benoit Viollet, Gerardo Ferbeyre, Michael N Pollak. Cancer Prev Res (Phila) 2012
213
4

Immune-mediated antitumor effect by type 2 diabetes drug, metformin.
Shingo Eikawa, Mikako Nishida, Shusaku Mizukami, Chihiro Yamazaki, Eiichi Nakayama, Heiichiro Udono. Proc Natl Acad Sci U S A 2015
303
4

Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1.
Jong-Ho Cha, Wen-Hao Yang, Weiya Xia, Yongkun Wei, Li-Chuan Chan, Seung-Oe Lim, Chia-Wei Li, Taewan Kim, Shih-Shin Chang, Heng-Huan Lee,[...]. Mol Cell 2018
237
4

Metformin in colorectal cancer: molecular mechanism, preclinical and clinical aspects.
Muhamad Noor Alfarizal Kamarudin, Md Moklesur Rahman Sarker, Jin-Rong Zhou, Ishwar Parhar. J Exp Clin Cancer Res 2019
53
7

Metformin and gut microbiota: their interactions and their impact on diabetes.
Natalia G Vallianou, Theodora Stratigou, Stylianos Tsagarakis. Hormones (Athens) 2019
36
11

Reduced risk of colorectal cancer with metformin therapy in patients with type 2 diabetes: a meta-analysis.
Zhi-Jiang Zhang, Zhi-Jie Zheng, Haidong Kan, Yiqing Song, Wei Cui, Genming Zhao, Kevin E Kip. Diabetes Care 2011
204
4


Metformin Is Associated With Higher Relative Abundance of Mucin-Degrading Akkermansia muciniphila and Several Short-Chain Fatty Acid-Producing Microbiota in the Gut.
Jacobo de la Cuesta-Zuluaga, Noel T Mueller, Vanessa Corrales-Agudelo, Eliana P Velásquez-Mejía, Jenny A Carmona, José M Abad, Juan S Escobar. Diabetes Care 2017
284
4

Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission.
Heather A Hirsch, Dimitrios Iliopoulos, Philip N Tsichlis, Kevin Struhl. Cancer Res 2009
815
4

Anticancer activity of metformin: a systematic review of the literature.
Mohamad Aljofan, Dieter Riethmacher. Future Sci OA 2019
48
8

Metformin.
C J Bailey, R C Turner. N Engl J Med 1996
4

Metformin and the intestine.
C J Bailey, C Wilcock, J H B Scarpello. Diabetologia 2008
141
4


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.