Valentin Gorboulev, Annette Schürmann, Volker Vallon, Helmut Kipp, Alexander Jaschke, Dirk Klessen, Alexandra Friedrich, Stephan Scherneck, Timo Rieg, Robyn Cunard, Maike Veyhl-Wichmann, Aruna Srinivasan, Daniela Balen, Davorka Breljak, Rexhep Rexhepaj, Helen E Parker, Fiona M Gribble, Frank Reimann, Florian Lang, Stefan Wiese, Ivan Sabolic, Michael Sendtner, Hermann Koepsell. Diabetes 2012
Times Cited: 396
Times Cited: 396
Times Cited
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Biology of human sodium glucose transporters.
Ernest M Wright, Donald D F Loo, Bruce A Hirayama. Physiol Rev 2011
Ernest M Wright, Donald D F Loo, Bruce A Hirayama. Physiol Rev 2011
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The role of SGLT1 and GLUT2 in intestinal glucose transport and sensing.
Pia V Röder, Kerstin E Geillinger, Tamara S Zietek, Bernard Thorens, Hermann Koepsell, Hannelore Daniel. PLoS One 2014
Pia V Röder, Kerstin E Geillinger, Tamara S Zietek, Bernard Thorens, Hermann Koepsell, Hannelore Daniel. PLoS One 2014
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Localizations of Na(+)-D-glucose cotransporters SGLT1 and SGLT2 in human kidney and of SGLT1 in human small intestine, liver, lung, and heart.
Ivana Vrhovac, Daniela Balen Eror, Dirk Klessen, Christa Burger, Davorka Breljak, Ognjen Kraus, Nikola Radović, Stipe Jadrijević, Ivan Aleksic, Thorsten Walles,[...]. Pflugers Arch 2015
Ivana Vrhovac, Daniela Balen Eror, Dirk Klessen, Christa Burger, Davorka Breljak, Ognjen Kraus, Nikola Radović, Stipe Jadrijević, Ivan Aleksic, Thorsten Walles,[...]. Pflugers Arch 2015
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Predominant role of active versus facilitative glucose transport for glucagon-like peptide-1 secretion.
H E Parker, A Adriaenssens, G Rogers, P Richards, H Koepsell, F Reimann, F M Gribble. Diabetologia 2012
H E Parker, A Adriaenssens, G Rogers, P Richards, H Koepsell, F Reimann, F M Gribble. Diabetologia 2012
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Glucose sensing in L cells: a primary cell study.
Frank Reimann, Abdella M Habib, Gwen Tolhurst, Helen E Parker, Gareth J Rogers, Fiona M Gribble. Cell Metab 2008
Frank Reimann, Abdella M Habib, Gwen Tolhurst, Helen E Parker, Gareth J Rogers, Fiona M Gribble. Cell Metab 2008
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Molecular mechanisms of glucose-stimulated GLP-1 secretion from perfused rat small intestine.
Rune E Kuhre, Charlotte R Frost, Berit Svendsen, Jens J Holst. Diabetes 2015
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Sugar absorption in the intestine: the role of GLUT2.
George L Kellett, Edith Brot-Laroche, Oliver J Mace, Armelle Leturque. Annu Rev Nutr 2008
George L Kellett, Edith Brot-Laroche, Oliver J Mace, Armelle Leturque. Annu Rev Nutr 2008
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LX4211 increases serum glucagon-like peptide 1 and peptide YY levels by reducing sodium/glucose cotransporter 1 (SGLT1)-mediated absorption of intestinal glucose.
David R Powell, Melinda Smith, Jennifer Greer, Angela Harris, Sharon Zhao, Christopher DaCosta, Faika Mseeh, Melanie K Shadoan, Arthur Sands, Brian Zambrowicz,[...]. J Pharmacol Exp Ther 2013
David R Powell, Melinda Smith, Jennifer Greer, Angela Harris, Sharon Zhao, Christopher DaCosta, Faika Mseeh, Melanie K Shadoan, Arthur Sands, Brian Zambrowicz,[...]. J Pharmacol Exp Ther 2013
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A novel glucose-sensing mechanism contributing to glucagon-like peptide-1 secretion from the GLUTag cell line.
Fiona M Gribble, Leanne Williams, Anna K Simpson, Frank Reimann. Diabetes 2003
Fiona M Gribble, Leanne Williams, Anna K Simpson, Frank Reimann. Diabetes 2003
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Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2.
Gwen Tolhurst, Helen Heffron, Yu Shan Lam, Helen E Parker, Abdella M Habib, Eleftheria Diakogiannaki, Jennifer Cameron, Johannes Grosse, Frank Reimann, Fiona M Gribble. Diabetes 2012
Gwen Tolhurst, Helen Heffron, Yu Shan Lam, Helen E Parker, Abdella M Habib, Eleftheria Diakogiannaki, Jennifer Cameron, Johannes Grosse, Frank Reimann, Fiona M Gribble. Diabetes 2012
14
Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1.
Hyeung-Jin Jang, Zaza Kokrashvili, Michael J Theodorakis, Olga D Carlson, Byung-Joon Kim, Jie Zhou, Hyeon Ho Kim, Xiangru Xu, Sic L Chan, Magdalena Juhaszova,[...]. Proc Natl Acad Sci U S A 2007
Hyeung-Jin Jang, Zaza Kokrashvili, Michael J Theodorakis, Olga D Carlson, Byung-Joon Kim, Jie Zhou, Hyeon Ho Kim, Xiangru Xu, Sic L Chan, Magdalena Juhaszova,[...]. Proc Natl Acad Sci U S A 2007
14
T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1.
Robert F Margolskee, Jane Dyer, Zaza Kokrashvili, Kieron S H Salmon, Erwin Ilegems, Kristian Daly, Emeline L Maillet, Yuzo Ninomiya, Bedrich Mosinger, Soraya P Shirazi-Beechey. Proc Natl Acad Sci U S A 2007
Robert F Margolskee, Jane Dyer, Zaza Kokrashvili, Kieron S H Salmon, Erwin Ilegems, Kristian Daly, Emeline L Maillet, Yuzo Ninomiya, Bedrich Mosinger, Soraya P Shirazi-Beechey. Proc Natl Acad Sci U S A 2007
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Expression of monosaccharide transporters in intestine of diabetic humans.
J Dyer, I S Wood, A Palejwala, A Ellis, S P Shirazi-Beechey. Am J Physiol Gastrointest Liver Physiol 2002
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SGLT2 mediates glucose reabsorption in the early proximal tubule.
Volker Vallon, Kenneth A Platt, Robyn Cunard, Jana Schroth, Jean Whaley, Scott C Thomson, Hermann Koepsell, Timo Rieg. J Am Soc Nephrol 2011
Volker Vallon, Kenneth A Platt, Robyn Cunard, Jana Schroth, Jean Whaley, Scott C Thomson, Hermann Koepsell, Timo Rieg. J Am Soc Nephrol 2011
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Mechanisms Controlling Glucose-Induced GLP-1 Secretion in Human Small Intestine.
Emily W Sun, Dayan de Fontgalland, Philippa Rabbitt, Paul Hollington, Luigi Sposato, Steven L Due, David A Wattchow, Christopher K Rayner, Adam M Deane, Richard L Young,[...]. Diabetes 2017
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Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia.
Timo Rieg, Takahiro Masuda, Maria Gerasimova, Eric Mayoux, Kenneth Platt, David R Powell, Scott C Thomson, Hermann Koepsell, Volker Vallon. Am J Physiol Renal Physiol 2014
Timo Rieg, Takahiro Masuda, Maria Gerasimova, Eric Mayoux, Kenneth Platt, David R Powell, Scott C Thomson, Hermann Koepsell, Volker Vallon. Am J Physiol Renal Physiol 2014
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Enteroendocrine Cells: Chemosensors in the Intestinal Epithelium.
Fiona M Gribble, Frank Reimann. Annu Rev Physiol 2016
Fiona M Gribble, Frank Reimann. Annu Rev Physiol 2016
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The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose.
Y Kanai, W S Lee, G You, D Brown, M A Hediger. J Clin Invest 1994
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Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients.
Ele Ferrannini, Elza Muscelli, Silvia Frascerra, Simona Baldi, Andrea Mari, Tim Heise, Uli C Broedl, Hans-Juergen Woerle. J Clin Invest 2014
Ele Ferrannini, Elza Muscelli, Silvia Frascerra, Simona Baldi, Andrea Mari, Tim Heise, Uli C Broedl, Hans-Juergen Woerle. J Clin Invest 2014
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Sodium glucose cotransporter SGLT1 as a therapeutic target in diabetes mellitus.
Panai Song, Akira Onishi, Hermann Koepsell, Volker Vallon. Expert Opin Ther Targets 2016
Panai Song, Akira Onishi, Hermann Koepsell, Volker Vallon. Expert Opin Ther Targets 2016
13
Expression cloning and cDNA sequencing of the Na+/glucose co-transporter.
M A Hediger, M J Coady, T S Ikeda, E M Wright. Nature 1987
M A Hediger, M J Coady, T S Ikeda, E M Wright. Nature 1987
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SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice.
Volker Vallon, Maria Gerasimova, Michael A Rose, Takahiro Masuda, Joseph Satriano, Eric Mayoux, Hermann Koepsell, Scott C Thomson, Timo Rieg. Am J Physiol Renal Physiol 2014
Volker Vallon, Maria Gerasimova, Michael A Rose, Takahiro Masuda, Joseph Satriano, Eric Mayoux, Hermann Koepsell, Scott C Thomson, Timo Rieg. Am J Physiol Renal Physiol 2014
9
Canagliflozin lowers postprandial glucose and insulin by delaying intestinal glucose absorption in addition to increasing urinary glucose excretion: results of a randomized, placebo-controlled study.
David Polidori, Sue Sha, Sunder Mudaliar, Theodore P Ciaraldi, Atalanta Ghosh, Nicole Vaccaro, Kristin Farrell, Paul Rothenberg, Robert R Henry. Diabetes Care 2013
David Polidori, Sue Sha, Sunder Mudaliar, Theodore P Ciaraldi, Atalanta Ghosh, Nicole Vaccaro, Kristin Farrell, Paul Rothenberg, Robert R Henry. Diabetes Care 2013
9
Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes.
Bernard Zinman, Christoph Wanner, John M Lachin, David Fitchett, Erich Bluhmki, Stefan Hantel, Michaela Mattheus, Theresa Devins, Odd Erik Johansen, Hans J Woerle,[...]. N Engl J Med 2015
Bernard Zinman, Christoph Wanner, John M Lachin, David Fitchett, Erich Bluhmki, Stefan Hantel, Michaela Mattheus, Theresa Devins, Odd Erik Johansen, Hans J Woerle,[...]. N Engl J Med 2015
9
Selective sodium-dependent glucose transporter 1 inhibitors block glucose absorption and impair glucose-dependent insulinotropic peptide release.
Robert L Dobbins, Frank L Greenway, Lihong Chen, Yaping Liu, Sharon L Breed, Susan M Andrews, Jeffrey A Wald, Ann Walker, Chari D Smith. Am J Physiol Gastrointest Liver Physiol 2015
Robert L Dobbins, Frank L Greenway, Lihong Chen, Yaping Liu, Sharon L Breed, Susan M Andrews, Jeffrey A Wald, Ann Walker, Chari D Smith. Am J Physiol Gastrointest Liver Physiol 2015
13
Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion.
Sara Edfalk, Pär Steneberg, Helena Edlund. Diabetes 2008
Sara Edfalk, Pär Steneberg, Helena Edlund. Diabetes 2008
9
The regulation of K- and L-cell activity by GLUT2 and the calcium-sensing receptor CasR in rat small intestine.
Oliver J Mace, Marcus Schindler, Sonal Patel. J Physiol 2012
Oliver J Mace, Marcus Schindler, Sonal Patel. J Physiol 2012
9
A gut-brain neural circuit for nutrient sensory transduction.
Melanie Maya Kaelberer, Kelly L Buchanan, Marguerita E Klein, Bradley B Barth, Marcia M Montoya, Xiling Shen, Diego V Bohórquez. Science 2018
Melanie Maya Kaelberer, Kelly L Buchanan, Marguerita E Klein, Bradley B Barth, Marcia M Montoya, Xiling Shen, Diego V Bohórquez. Science 2018
9
Activation of sodium-glucose cotransporter 1 ameliorates hyperglycemia by mediating incretin secretion in mice.
Ryuichi Moriya, Takashi Shirakura, Junko Ito, Satoshi Mashiko, Toru Seo. Am J Physiol Endocrinol Metab 2009
Ryuichi Moriya, Takashi Shirakura, Junko Ito, Satoshi Mashiko, Toru Seo. Am J Physiol Endocrinol Metab 2009
9
KGA-2727, a novel selective inhibitor of a high-affinity sodium glucose cotransporter (SGLT1), exhibits antidiabetic efficacy in rodent models.
Toshihide Shibazaki, Masaki Tomae, Yukiko Ishikawa-Takemura, Nobuhiko Fushimi, Fumiaki Itoh, Mitsuhiko Yamada, Masayuki Isaji. J Pharmacol Exp Ther 2012
Toshihide Shibazaki, Masaki Tomae, Yukiko Ishikawa-Takemura, Nobuhiko Fushimi, Fumiaki Itoh, Mitsuhiko Yamada, Masayuki Isaji. J Pharmacol Exp Ther 2012
15
Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes.
Hassan Rahmoune, Paul W Thompson, Joanna M Ward, Chari D Smith, Guizhu Hong, John Brown. Diabetes 2005
Hassan Rahmoune, Paul W Thompson, Joanna M Ward, Chari D Smith, Guizhu Hong, John Brown. Diabetes 2005
8
A glucose sensor hiding in a family of transporters.
Ana Diez-Sampedro, Bruce A Hirayama, Christina Osswald, Valentin Gorboulev, Katharina Baumgarten, Christopher Volk, Ernest M Wright, Hermann Koepsell. Proc Natl Acad Sci U S A 2003
Ana Diez-Sampedro, Bruce A Hirayama, Christina Osswald, Valentin Gorboulev, Katharina Baumgarten, Christopher Volk, Ernest M Wright, Hermann Koepsell. Proc Natl Acad Sci U S A 2003
8
Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion.
Caroline Bonner, Julie Kerr-Conte, Valéry Gmyr, Gurvan Queniat, Ericka Moerman, Julien Thévenet, Cédric Beaucamps, Nathalie Delalleau, Iuliana Popescu, Willy J Malaisse,[...]. Nat Med 2015
Caroline Bonner, Julie Kerr-Conte, Valéry Gmyr, Gurvan Queniat, Ericka Moerman, Julien Thévenet, Cédric Beaucamps, Nathalie Delalleau, Iuliana Popescu, Willy J Malaisse,[...]. Nat Med 2015
8
Expression profiling and immunolocalization of Na+-D-glucose-cotransporter 1 in mice employing knockout mice as specificity control indicate novel locations and differences between mice and rats.
Ivana Vrhovac Madunić, Davorka Breljak, Dean Karaica, Hermann Koepsell, Ivan Sabolić. Pflugers Arch 2017
Ivana Vrhovac Madunić, Davorka Breljak, Dean Karaica, Hermann Koepsell, Ivan Sabolić. Pflugers Arch 2017
38
Revised immunolocalization of the Na+-D-glucose cotransporter SGLT1 in rat organs with an improved antibody.
Daniela Balen, Marija Ljubojevic, Davorka Breljak, Hrvoje Brzica, Vilim Zlender, Hermann Koepsell, Ivan Sabolic. Am J Physiol Cell Physiol 2008
Daniela Balen, Marija Ljubojevic, Davorka Breljak, Hrvoje Brzica, Vilim Zlender, Hermann Koepsell, Ivan Sabolic. Am J Physiol Cell Physiol 2008
8
Vascular, but not luminal, activation of FFAR1 (GPR40) stimulates GLP-1 secretion from isolated perfused rat small intestine.
Louise W Christensen, Rune E Kuhre, Charlotte Janus, Berit Svendsen, Jens J Holst. Physiol Rep 2015
Louise W Christensen, Rune E Kuhre, Charlotte Janus, Berit Svendsen, Jens J Holst. Physiol Rep 2015
14
The impact of short-chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon.
Charlotte Bayer Christiansen, Maria Buur Nordskov Gabe, Berit Svendsen, Lars Ove Dragsted, Mette Marie Rosenkilde, Jens Juul Holst. Am J Physiol Gastrointest Liver Physiol 2018
Charlotte Bayer Christiansen, Maria Buur Nordskov Gabe, Berit Svendsen, Lars Ove Dragsted, Mette Marie Rosenkilde, Jens Juul Holst. Am J Physiol Gastrointest Liver Physiol 2018
9
Oligopeptides stimulate glucagon-like peptide-1 secretion in mice through proton-coupled uptake and the calcium-sensing receptor.
Eleftheria Diakogiannaki, Ramona Pais, Gwen Tolhurst, Helen E Parker, James Horscroft, Beate Rauscher, Tamara Zietek, Hannelore Daniel, Fiona M Gribble, Frank Reimann. Diabetologia 2013
Eleftheria Diakogiannaki, Ramona Pais, Gwen Tolhurst, Helen E Parker, James Horscroft, Beate Rauscher, Tamara Zietek, Hannelore Daniel, Fiona M Gribble, Frank Reimann. Diabetologia 2013
8
Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry.
Abdella M Habib, Paul Richards, Lynne S Cairns, Gareth J Rogers, Christopher A M Bannon, Helen E Parker, Tom C E Morley, Giles S H Yeo, Frank Reimann, Fiona M Gribble. Endocrinology 2012
Abdella M Habib, Paul Richards, Lynne S Cairns, Gareth J Rogers, Christopher A M Bannon, Helen E Parker, Tom C E Morley, Giles S H Yeo, Frank Reimann, Fiona M Gribble. Endocrinology 2012
8
A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin.
Kristoffer L Egerod, Maja S Engelstoft, Kaare V Grunddal, Mark K Nøhr, Anna Secher, Ichiro Sakata, Jens Pedersen, Johanne A Windeløv, Ernst-Martin Füchtbauer, Jørgen Olsen,[...]. Endocrinology 2012
Kristoffer L Egerod, Maja S Engelstoft, Kaare V Grunddal, Mark K Nøhr, Anna Secher, Ichiro Sakata, Jens Pedersen, Johanne A Windeløv, Ernst-Martin Füchtbauer, Jørgen Olsen,[...]. Endocrinology 2012
8
8
Accelerated intestinal glucose absorption in morbidly obese humans: relationship to glucose transporters, incretin hormones, and glycemia.
Nam Q Nguyen, Tamara L Debreceni, Jenna E Bambrick, Bridgette Chia, Judith Wishart, Adam M Deane, Chris K Rayner, Michael Horowitz, Richard L Young. J Clin Endocrinol Metab 2015
Nam Q Nguyen, Tamara L Debreceni, Jenna E Bambrick, Bridgette Chia, Judith Wishart, Adam M Deane, Chris K Rayner, Michael Horowitz, Richard L Young. J Clin Endocrinol Metab 2015
15
The SLC2 (GLUT) family of membrane transporters.
Mike Mueckler, Bernard Thorens. Mol Aspects Med 2013
Mike Mueckler, Bernard Thorens. Mol Aspects Med 2013
8
Glucagon-like peptide 1 (GLP-1).
T D Müller, B Finan, S R Bloom, D D'Alessio, D J Drucker, P R Flatt, A Fritsche, F Gribble, H J Grill, J F Habener,[...]. Mol Metab 2019
T D Müller, B Finan, S R Bloom, D D'Alessio, D J Drucker, P R Flatt, A Fritsche, F Gribble, H J Grill, J F Habener,[...]. Mol Metab 2019
8
Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production.
Aurora Merovci, Carolina Solis-Herrera, Giuseppe Daniele, Roy Eldor, Teresa Vanessa Fiorentino, Devjit Tripathy, Juan Xiong, Zandra Perez, Luke Norton, Muhammad A Abdul-Ghani,[...]. J Clin Invest 2014
Aurora Merovci, Carolina Solis-Herrera, Giuseppe Daniele, Roy Eldor, Teresa Vanessa Fiorentino, Devjit Tripathy, Juan Xiong, Zandra Perez, Luke Norton, Muhammad A Abdul-Ghani,[...]. J Clin Invest 2014
7
Simple-sugar meals target GLUT2 at enterocyte apical membranes to improve sugar absorption: a study in GLUT2-null mice.
F Gouyon, L Caillaud, V Carriere, C Klein, V Dalet, D Citadelle, G L Kellett, B Thorens, A Leturque, E Brot-Laroche. J Physiol 2003
F Gouyon, L Caillaud, V Carriere, C Klein, V Dalet, D Citadelle, G L Kellett, B Thorens, A Leturque, E Brot-Laroche. J Physiol 2003
7
LX4211, a dual SGLT1/SGLT2 inhibitor, improved glycemic control in patients with type 2 diabetes in a randomized, placebo-controlled trial.
B Zambrowicz, J Freiman, P M Brown, K S Frazier, A Turnage, J Bronner, D Ruff, M Shadoan, P Banks, F Mseeh,[...]. Clin Pharmacol Ther 2012
B Zambrowicz, J Freiman, P M Brown, K S Frazier, A Turnage, J Bronner, D Ruff, M Shadoan, P Banks, F Mseeh,[...]. Clin Pharmacol Ther 2012
7
The Na+-D-glucose cotransporters SGLT1 and SGLT2 are targets for the treatment of diabetes and cancer.
Hermann Koepsell. Pharmacol Ther 2017
Hermann Koepsell. Pharmacol Ther 2017
14
Improved glycemic control in mice lacking Sglt1 and Sglt2.
David R Powell, Christopher M DaCosta, Jason Gay, Zhi-Ming Ding, Melinda Smith, Jennifer Greer, Deon Doree, Sabrina Jeter-Jones, Faika Mseeh, Lawrence A Rodriguez,[...]. Am J Physiol Endocrinol Metab 2013
David R Powell, Christopher M DaCosta, Jason Gay, Zhi-Ming Ding, Melinda Smith, Jennifer Greer, Deon Doree, Sabrina Jeter-Jones, Faika Mseeh, Lawrence A Rodriguez,[...]. Am J Physiol Endocrinol Metab 2013
7
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.