A citation-based method for searching scientific literature

Carolyn Algire, Olga Moiseeva, Xavier Deschênes-Simard, Lilian Amrein, Luca Petruccelli, Elena Birman, Benoit Viollet, Gerardo Ferbeyre, Michael N Pollak. Cancer Prev Res (Phila) 2012
Times Cited: 200







List of co-cited articles
978 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Metformin improves healthspan and lifespan in mice.
Alejandro Martin-Montalvo, Evi M Mercken, Sarah J Mitchell, Hector H Palacios, Patricia L Mote, Morten Scheibye-Knudsen, Ana P Gomes, Theresa M Ward, Robin K Minor, Marie-José Blouin,[...]. Nat Commun 2013
662
22

Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-κB activation.
Olga Moiseeva, Xavier Deschênes-Simard, Emmanuelle St-Germain, Sebastian Igelmann, Geneviève Huot, Alexandra E Cadar, Véronique Bourdeau, Michael N Pollak, Gerardo Ferbeyre. Aging Cell 2013
225
20

Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1.
Isaam Ben Sahra, Claire Regazzetti, Guillaume Robert, Kathiane Laurent, Yannick Le Marchand-Brustel, Patrick Auberger, Jean-François Tanti, Sophie Giorgetti-Peraldi, Frédéric Bost. Cancer Res 2011
423
17

Role of AMP-activated protein kinase in mechanism of metformin action.
G Zhou, R Myers, Y Li, Y Chen, X Shen, J Fenyk-Melody, M Wu, J Ventre, T Doebber, N Fujii,[...]. J Clin Invest 2001
17

Metformin as a Tool to Target Aging.
Nir Barzilai, Jill P Crandall, Stephen B Kritchevsky, Mark A Espeland. Cell Metab 2016
405
17

Metformin and reduced risk of cancer in diabetic patients.
Josie M M Evans, Louise A Donnelly, Alistair M Emslie-Smith, Dario R Alessi, Andrew D Morris. BMJ 2005
16

Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism.
Filipe Cabreiro, Catherine Au, Kit-Yi Leung, Nuria Vergara-Irigaray, Helena M Cochemé, Tahereh Noori, David Weinkove, Eugene Schuster, Nicholas D E Greene, David Gems. Cell 2013
494
16

Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis.
William W Wheaton, Samuel E Weinberg, Robert B Hamanaka, Saul Soberanes, Lucas B Sullivan, Elena Anso, Andrea Glasauer, Eric Dufour, Gokhan M Mutlu, Gr Scott Budigner,[...]. Elife 2014
557
15

Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria.
Hannah R Bridges, Andrew J Y Jones, Michael N Pollak, Judy Hirst. Biochem J 2014
350
13

Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner.
Adem Kalender, Anand Selvaraj, So Young Kim, Pawan Gulati, Sophie Brûlé, Benoit Viollet, Bruce E Kemp, Nabeel Bardeesy, Patrick Dennis, John J Schlager,[...]. Cell Metab 2010
566
12

Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.
M Y El-Mir, V Nogueira, E Fontaine, N Avéret, M Rigoulet, X Leverve. J Biol Chem 2000
922
11

The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin.
Reuben J Shaw, Katja A Lamia, Debbie Vasquez, Seung-Hoi Koo, Nabeel Bardeesy, Ronald A Depinho, Marc Montminy, Lewis C Cantley. Science 2005
11

Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase.
Anila K Madiraju, Derek M Erion, Yasmeen Rahimi, Xian-Man Zhang, Demetrios T Braddock, Ronald A Albright, Brett J Prigaro, John L Wood, Sanjay Bhanot, Michael J MacDonald,[...]. Nature 2014
662
11

Cellular and molecular mechanisms of metformin: an overview.
Benoit Viollet, Bruno Guigas, Nieves Sanz Garcia, Jocelyne Leclerc, Marc Foretz, Fabrizio Andreelli. Clin Sci (Lond) 2012
948
11

Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth.
Heather A Hirsch, Dimitrios Iliopoulos, Kevin Struhl. Proc Natl Acad Sci U S A 2013
294
11


Metformin--mode of action and clinical implications for diabetes and cancer.
Ida Pernicova, Márta Korbonits. Nat Rev Endocrinol 2014
596
10

Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP.
Russell A Miller, Qingwei Chu, Jianxin Xie, Marc Foretz, Benoit Viollet, Morris J Birnbaum. Nature 2013
492
10

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.
Marc Foretz, Sophie Hébrard, Jocelyne Leclerc, Elham Zarrinpashneh, Maud Soty, Gilles Mithieux, Kei Sakamoto, Fabrizio Andreelli, Benoit Viollet. J Clin Invest 2010
800
10

Metformin promotes lifespan through mitohormesis via the peroxiredoxin PRDX-2.
Wouter De Haes, Lotte Frooninckx, Roel Van Assche, Arne Smolders, Geert Depuydt, Johan Billen, Bart P Braeckman, Liliane Schoofs, Liesbet Temmerman. Proc Natl Acad Sci U S A 2014
181
10


Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission.
Heather A Hirsch, Dimitrios Iliopoulos, Philip N Tsichlis, Kevin Struhl. Cancer Res 2009
799
9

The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level.
I Ben Sahra, K Laurent, A Loubat, S Giorgetti-Peraldi, P Colosetti, P Auberger, J F Tanti, Y Le Marchand-Brustel, F Bost. Oncogene 2008
634
9

Metformin and cancer risk in diabetic patients: a systematic review and meta-analysis.
Andrea Decensi, Matteo Puntoni, Pamela Goodwin, Massimiliano Cazzaniga, Alessandra Gennari, Bernardo Bonanni, Sara Gandini. Cancer Prev Res (Phila) 2010
599
9

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
Yi Zhu, Tamara Tchkonia, Tamar Pirtskhalava, Adam C Gower, Husheng Ding, Nino Giorgadze, Allyson K Palmer, Yuji Ikeno, Gene B Hubbard, Marc Lenburg,[...]. Aging Cell 2015
733
9

The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
9

The ROS production induced by a reverse-electron flux at respiratory-chain complex 1 is hampered by metformin.
Cécile Batandier, Bruno Guigas, Dominique Detaille, M-Yehia El-Mir, Eric Fontaine, M Rigoulet, Xavier M Leverve. J Bioenerg Biomembr 2006
181
9

Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study.
Jamie N Justice, Anoop M Nambiar, Tamar Tchkonia, Nathan K LeBrasseur, Rodolfo Pascual, Shahrukh K Hashmi, Larissa Prata, Michal M Masternak, Stephen B Kritchevsky, Nicolas Musi,[...]. EBioMedicine 2019
296
9

Metformin alleviates hepatosteatosis by restoring SIRT1-mediated autophagy induction via an AMP-activated protein kinase-independent pathway.
Young Mi Song, Yong-ho Lee, Ji-Won Kim, Dong-Sik Ham, Eun-Seok Kang, Bong Soo Cha, Hyun Chul Lee, Byung-Wan Lee. Autophagy 2015
147
8

Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer.
Sao Jiralerspong, Shana L Palla, Sharon H Giordano, Funda Meric-Bernstam, Cornelia Liedtke, Chad M Barnett, Limin Hsu, Mien-Chie Hung, Gabriel N Hortobagyi, Ana M Gonzalez-Angulo. J Clin Oncol 2009
628
8

Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy.
W-Y Shi, D Xiao, L Wang, L-H Dong, Z-X Yan, Z-X Shen, S-J Chen, Y Chen, W-L Zhao. Cell Death Dis 2012
204
8

AMPK phosphorylation of raptor mediates a metabolic checkpoint.
Dana M Gwinn, David B Shackelford, Daniel F Egan, Maria M Mihaylova, Annabelle Mery, Debbie S Vasquez, Benjamin E Turk, Reuben J Shaw. Mol Cell 2008
8

Immune-mediated antitumor effect by type 2 diabetes drug, metformin.
Shingo Eikawa, Mikako Nishida, Shusaku Mizukami, Chihiro Yamazaki, Eiichi Nakayama, Heiichiro Udono. Proc Natl Acad Sci U S A 2015
281
8

Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth.
Monica Buzzai, Russell G Jones, Ravi K Amaravadi, Julian J Lum, Ralph J DeBerardinis, Fangping Zhao, Benoit Viollet, Craig B Thompson. Cancer Res 2007
715
8

Metformin: historical overview.
Clifford J Bailey. Diabetologia 2017
228
8

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.
Darren J Baker, Tobias Wijshake, Tamar Tchkonia, Nathan K LeBrasseur, Bennett G Childs, Bart van de Sluis, James L Kirkland, Jan M van Deursen. Nature 2011
8


Metformin reduces intracellular reactive oxygen species levels by upregulating expression of the antioxidant thioredoxin via the AMPK-FOXO3 pathway.
Xinguo Hou, Jun Song, Xiao-Nan Li, Lin Zhang, XingLi Wang, Li Chen, Ying H Shen. Biochem Biophys Res Commun 2010
141
7

Metformin slows down aging and extends life span of female SHR mice.
Vladimir N Anisimov, Lev M Berstein, Peter A Egormin, Tatiana S Piskunova, Irina G Popovich, Mark A Zabezhinski, Margarita L Tyndyk, Maria V Yurova, Irina G Kovalenko, Tatiana E Poroshina,[...]. Cell Cycle 2008
214
7

Metformin action: concentrations matter.
Ling He, Fredric E Wondisford. Cell Metab 2015
210
7

AMP-activated protein kinase induces a p53-dependent metabolic checkpoint.
Russell G Jones, David R Plas, Sara Kubek, Monica Buzzai, James Mu, Yang Xu, Morris J Birnbaum, Craig B Thompson. Mol Cell 2005
7

An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA.
Marco Demaria, Naoko Ohtani, Sameh A Youssef, Francis Rodier, Wendy Toussaint, James R Mitchell, Remi-Martin Laberge, Jan Vijg, Harry Van Steeg, Martijn E T Dollé,[...]. Dev Cell 2014
739
7

Metformin in cancer: translational challenges.
Ryan J O Dowling, Saroj Niraula, Vuk Stambolic, Pamela J Goodwin. J Mol Endocrinol 2012
227
7

Effect of metformin on life span and on the development of spontaneous mammary tumors in HER-2/neu transgenic mice.
Vladimir N Anisimov, Lev M Berstein, Peter A Egormin, Tatiana S Piskunova, Irina G Popovich, Mark A Zabezhinski, Irina G Kovalenko, Tatiana E Poroshina, Anna V Semenchenko, Mauro Provinciali,[...]. Exp Gerontol 2005
293
7

The radioprotective effect of metformin against cytotoxicity and genotoxicity induced by ionizing radiation in cultured human blood lymphocytes.
Mohsen Cheki, Alireza Shirazi, Aziz Mahmoudzadeh, Javad Tavakkoly Bazzaz, Seyed Jalal Hosseinimehr. Mutat Res Genet Toxicol Environ Mutagen 2016
29
24

The mechanisms of action of metformin.
Graham Rena, D Grahame Hardie, Ewan R Pearson. Diabetologia 2017
632
7

Metformin Activates AMPK through the Lysosomal Pathway.
Chen-Song Zhang, Mengqi Li, Teng Ma, Yue Zong, Jiwen Cui, Jin-Wei Feng, Yu-Qing Wu, Shu-Yong Lin, Sheng-Cai Lin. Cell Metab 2016
106
7


The senescence-associated secretory phenotype: the dark side of tumor suppression.
Jean-Philippe Coppé, Pierre-Yves Desprez, Ana Krtolica, Judith Campisi. Annu Rev Pathol 2010
7



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.