A citation-based method for searching scientific literature

C A Hoeffer, E Sanchez, R J Hagerman, Y Mu, D V Nguyen, H Wong, A M Whelan, R S Zukin, E Klann, F Tassone. Genes Brain Behav 2012
Times Cited: 133







List of co-cited articles
1594 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Dysregulation of mTOR signaling in fragile X syndrome.
Ali Sharma, Charles A Hoeffer, Yukihiro Takayasu, Takahiro Miyawaki, Sean M McBride, Eric Klann, R Suzanne Zukin. J Neurosci 2010
407
61

FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism.
Jennifer C Darnell, Sarah J Van Driesche, Chaolin Zhang, Ka Ying Sharon Hung, Aldo Mele, Claire E Fraser, Elizabeth F Stone, Cynthia Chen, John J Fak, Sung Wook Chi,[...]. Cell 2011
37

Genetic removal of p70 S6 kinase 1 corrects molecular, synaptic, and behavioral phenotypes in fragile X syndrome mice.
Aditi Bhattacharya, Hanoch Kaphzan, Amanda C Alvarez-Dieppa, Jaclyn P Murphy, Philippe Pierre, Eric Klann. Neuron 2012
216
33

Altered synaptic plasticity in a mouse model of fragile X mental retardation.
Kimberly M Huber, Sean M Gallagher, Stephen T Warren, Mark F Bear. Proc Natl Acad Sci U S A 2002
973
27

Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice.
Aubin Michalon, Michael Sidorov, Theresa M Ballard, Laurence Ozmen, Will Spooren, Joseph G Wettstein, Georg Jaeschke, Mark F Bear, Lothar Lindemann. Neuron 2012
352
25

The mGluR theory of fragile X mental retardation.
Mark F Bear, Kimberly M Huber, Stephen T Warren. Trends Neurosci 2004
25

Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile X syndrome.
Christina Gross, Mika Nakamoto, Xiaodi Yao, Chi-Bun Chan, So Y Yim, Keqiang Ye, Stephen T Warren, Gary J Bassell. J Neurosci 2010
188
25

Correction of fragile X syndrome in mice.
Gül Dölen, Emily Osterweil, B S Shankaranarayana Rao, Gordon B Smith, Benjamin D Auerbach, Sumantra Chattarji, Mark F Bear. Neuron 2007
700
24



Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome.
A J Verkerk, M Pieretti, J S Sutcliffe, Y H Fu, D P Kuhl, A Pizzuti, O Reiner, S Richards, M F Victoria, F P Zhang. Cell 1991
23

Autism-related deficits via dysregulated eIF4E-dependent translational control.
Christos G Gkogkas, Arkady Khoutorsky, Israeli Ran, Emmanouil Rampakakis, Tatiana Nevarko, Daniel B Weatherill, Cristina Vasuta, Stephanie Yee, Morgan Truitt, Paul Dallaire,[...]. Nature 2013
352
20

Mutations causing syndromic autism define an axis of synaptic pathophysiology.
Benjamin D Auerbach, Emily K Osterweil, Mark F Bear. Nature 2011
431
19

The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP.
Ilaria Napoli, Valentina Mercaldo, Pietro Pilo Boyl, Boris Eleuteri, Francesca Zalfa, Silvia De Rubeis, Daniele Di Marino, Evita Mohr, Marzia Massimi, Mattia Falconi,[...]. Cell 2008
412
18


Minocycline promotes dendritic spine maturation and improves behavioural performance in the fragile X mouse model.
T V Bilousova, L Dansie, M Ngo, J Aye, J R Charles, D W Ethell, I M Ethell. J Med Genet 2009
318
17

FMRP targets distinct mRNA sequence elements to regulate protein expression.
Manuel Ascano, Neelanjan Mukherjee, Pradeep Bandaru, Jason B Miller, Jeffrey D Nusbaum, David L Corcoran, Christine Langlois, Mathias Munschauer, Scott Dewell, Markus Hafner,[...]. Nature 2012
456
17

Lovastatin corrects excess protein synthesis and prevents epileptogenesis in a mouse model of fragile X syndrome.
Emily K Osterweil, Shih-Chieh Chuang, Alexander A Chubykin, Michael Sidorov, Riccardo Bianchi, Robert K S Wong, Mark F Bear. Neuron 2013
156
17

Molecular mechanisms of fragile X syndrome: a twenty-year perspective.
Michael R Santoro, Steven M Bray, Stephen T Warren. Annu Rev Pathol 2012
357
17

Dynamic translational and proteasomal regulation of fragile X mental retardation protein controls mGluR-dependent long-term depression.
Lingfei Hou, Marcia D Antion, Daoying Hu, Corinne M Spencer, Richard Paylor, Eric Klann. Neuron 2006
350
16

Genetic removal of matrix metalloproteinase 9 rescues the symptoms of fragile X syndrome in a mouse model.
Harpreet Sidhu, Lorraine E Dansie, Peter W Hickmott, Douglas W Ethell, Iryna M Ethell. J Neurosci 2014
111
16

Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP.
Q J Yan, M Rammal, M Tranfaglia, R P Bauchwitz. Neuropharmacology 2005
393
15


Identification of fragile X syndrome specific molecular markers in human fibroblasts: a useful model to test the efficacy of therapeutic drugs.
Daman Kumari, Aditi Bhattacharya, Jeffrey Nadel, Kristen Moulton, Nicole M Zeak, Anne Glicksman, Carl Dobkin, David J Brick, Philip H Schwartz, Carolyn B Smith,[...]. Hum Mutat 2014
43
34

Increased expression of the PI3K enhancer PIKE mediates deficits in synaptic plasticity and behavior in fragile X syndrome.
Christina Gross, Chia-Wei Chang, Seth M Kelly, Aditi Bhattacharya, Sean M J McBride, Scott W Danielson, Michael Q Jiang, Chi Bun Chan, Keqiang Ye, Jay R Gibson,[...]. Cell Rep 2015
74
20

Pharmacogenetic inhibition of eIF4E-dependent Mmp9 mRNA translation reverses fragile X syndrome-like phenotypes.
Christos G Gkogkas, Arkady Khoutorsky, Ruifeng Cao, Seyed Mehdi Jafarnejad, Masha Prager-Khoutorsky, Nikolaos Giannakas, Archontia Kaminari, Apostolia Fragkouli, Karim Nader, Theodore J Price,[...]. Cell Rep 2014
124
15

Exaggerated translation causes synaptic and behavioural aberrations associated with autism.
Emanuela Santini, Thu N Huynh, Andrew F MacAskill, Adam G Carter, Philippe Pierre, Davide Ruggero, Hanoch Kaphzan, Eric Klann. Nature 2013
252
14

High MMP-9 activity levels in fragile X syndrome are lowered by minocycline.
Magdalena Dziembowska, Dalyir I Pretto, Aleksandra Janusz, Leszek Kaczmarek, Mary Jacena Leigh, Nielsen Gabriel, Blythe Durbin-Johnson, Randi J Hagerman, Flora Tassone. Am J Med Genet A 2013
110
14

Early-phase ERK activation as a biomarker for metabolic status in fragile X syndrome.
Ning Weng, Ivan Jeanne Weiler, Allison Sumis, Elizabeth Berry-Kravis, William T Greenough. Am J Med Genet B Neuropsychiatr Genet 2008
47
29

Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits.
Guomei Tang, Kathryn Gudsnuk, Sheng-Han Kuo, Marisa L Cotrina, Gorazd Rosoklija, Alexander Sosunov, Mark S Sonders, Ellen Kanter, Candace Castagna, Ai Yamamoto,[...]. Neuron 2014
588
14

Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: a quantitative examination.
S A Irwin, B Patel, M Idupulapati, J B Harris, R A Crisostomo, B P Larsen, F Kooy, P J Willems, P Cras, P B Kozlowski,[...]. Am J Med Genet 2001
519
13

A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome.
Jason B Dictenberg, Sharon A Swanger, Laura N Antar, Robert H Singer, Gary J Bassell. Dev Cell 2008
353
13

Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome.
V Brown, P Jin, S Ceman, J C Darnell, W T O'Donnell, S A Tenenbaum, X Jin, Y Feng, K D Wilkinson, J D Keene,[...]. Cell 2001
861
13

A randomized double-blind, placebo-controlled trial of minocycline in children and adolescents with fragile x syndrome.
Mary Jacena S Leigh, Danh V Nguyen, Yi Mu, Tri I Winarni, Andrea Schneider, Tasleem Chechi, Jonathan Polussa, Paul Doucet, Flora Tassone, Susan M Rivera,[...]. J Dev Behav Pediatr 2013
157
13

Selective role of the catalytic PI3K subunit p110β in impaired higher order cognition in fragile X syndrome.
Christina Gross, Nisha Raj, Gemma Molinaro, Amanda G Allen, Alonzo J Whyte, Jay R Gibson, Kimberly M Huber, Shannon L Gourley, Gary J Bassell. Cell Rep 2015
58
22

Metformin ameliorates core deficits in a mouse model of fragile X syndrome.
Ilse Gantois, Arkady Khoutorsky, Jelena Popic, Argel Aguilar-Valles, Erika Freemantle, Ruifeng Cao, Vijendra Sharma, Tine Pooters, Anmol Nagpal, Agnieszka Skalecka,[...]. Nat Med 2017
112
13


The autistic neuron: troubled translation?
Raymond J Kelleher, Mark F Bear. Cell 2008
414
12

Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function.
J C Darnell, K B Jensen, P Jin, V Brown, S T Warren, R B Darnell. Cell 2001
738
12

Reversal of fragile X phenotypes by manipulation of AβPP/Aβ levels in Fmr1KO mice.
Cara J Westmark, Pamela R Westmark, Kenneth J O'Riordan, Brian C Ray, Crystal M Hervey, M Shahriar Salamat, Sara H Abozeid, Kelsey M Stein, Levi A Stodola, Michael Tranfaglia,[...]. PLoS One 2011
84
14

Pten regulates neuronal arborization and social interaction in mice.
Chang-Hyuk Kwon, Bryan W Luikart, Craig M Powell, Jing Zhou, Sharon A Matheny, Wei Zhang, Yanjiao Li, Suzanne J Baker, Luis F Parada. Neuron 2006
692
12

Open-label treatment trial of lithium to target the underlying defect in fragile X syndrome.
Elizabeth Berry-Kravis, Allison Sumis, Crystal Hervey, Michael Nelson, Stephen W Porges, Ning Weng, Ivan Jeanne Weiler, William T Greenough. J Dev Behav Pediatr 2008
164
12

Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486.
Bridget M Dolan, Sergio G Duron, David A Campbell, Benedikt Vollrath, B S Shankaranarayana Rao, Hui-Yeon Ko, Gregory G Lin, Arvind Govindarajan, Se-Young Choi, Susumu Tonegawa. Proc Natl Acad Sci U S A 2013
146
12

Epigenetic modification of the FMR1 gene in fragile X syndrome is associated with differential response to the mGluR5 antagonist AFQ056.
Sébastien Jacquemont, Aurore Curie, Vincent des Portes, Maria Giulia Torrioli, Elizabeth Berry-Kravis, Randi J Hagerman, Feliciano J Ramos, Kim Cornish, Yunsheng He, Charles Paulding,[...]. Sci Transl Med 2011
257
12

Targeting the endocannabinoid system in the treatment of fragile X syndrome.
Arnau Busquets-Garcia, Maria Gomis-González, Thomas Guegan, Carmen Agustín-Pavón, Antoni Pastor, Susana Mato, Alberto Pérez-Samartín, Carlos Matute, Rafael de la Torre, Mara Dierssen,[...]. Nat Med 2013
144
12

Dysregulation and restoration of translational homeostasis in fragile X syndrome.
Joel D Richter, Gary J Bassell, Eric Klann. Nat Rev Neurosci 2015
164
12

Elevated ERK/p90 ribosomal S6 kinase activity underlies audiogenic seizure susceptibility in fragile X mice.
Kirsty Sawicka, Alexander Pyronneau, Miranda Chao, Michael V L Bennett, R Suzanne Zukin. Proc Natl Acad Sci U S A 2016
44
27


A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability.
Francesca Zalfa, Boris Eleuteri, Kirsten S Dickson, Valentina Mercaldo, Silvia De Rubeis, Alessandra di Penta, Elisabetta Tabolacci, Pietro Chiurazzi, Giovanni Neri, Seth G N Grant,[...]. Nat Neurosci 2007
277
11

Elevated glycogen synthase kinase-3 activity in Fragile X mice: key metabolic regulator with evidence for treatment potential.
Wenzhong William Min, Christopher J Yuskaitis, Qijiang Yan, Christopher Sikorski, Shengqiang Chen, Richard S Jope, Robert P Bauchwitz. Neuropharmacology 2009
102
11


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.