A citation-based method for searching scientific literature

Ffolliott M Fisher, Sandra Kleiner, Nicholas Douris, Elliott C Fox, Rina J Mepani, Francisco Verdeguer, Jun Wu, Alexei Kharitonenkov, Jeffrey S Flier, Eleftheria Maratos-Flier, Bruce M Spiegelman. Genes Dev 2012
Times Cited: 1003







List of co-cited articles
1061 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


FGF-21 as a novel metabolic regulator.
Alexei Kharitonenkov, Tatiyana L Shiyanova, Anja Koester, Amy M Ford, Radmila Micanovic, Elizabeth J Galbreath, George E Sandusky, Lisa J Hammond, Julie S Moyers, Rebecca A Owens,[...]. J Clin Invest 2005
25

Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states.
Michael K Badman, Pavlos Pissios, Adam R Kennedy, George Koukos, Jeffrey S Flier, Eleftheria Maratos-Flier. Cell Metab 2007
21

Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21.
Takeshi Inagaki, Paul Dutchak, Guixiang Zhao, Xunshan Ding, Laurent Gautron, Vinay Parameswara, Yong Li, Regina Goetz, Moosa Mohammadi, Victoria Esser,[...]. Cell Metab 2007
19

Thermogenic activation induces FGF21 expression and release in brown adipose tissue.
Elayne Hondares, Roser Iglesias, Albert Giralt, Frank J Gonzalez, Marta Giralt, Teresa Mampel, Francesc Villarroya. J Biol Chem 2011
406
19

Circulating FGF21 is liver derived and enhances glucose uptake during refeeding and overfeeding.
Kathleen R Markan, Meghan C Naber, Magdalene K Ameka, Maxwell D Anderegg, David J Mangelsdorf, Steven A Kliewer, Moosa Mohammadi, Matthew J Potthoff. Diabetes 2014
347
18

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis.
Pontus Boström, Jun Wu, Mark P Jedrychowski, Anisha Korde, Li Ye, James C Lo, Kyle A Rasbach, Elisabeth Almer Boström, Jang Hyun Choi, Jonathan Z Long,[...]. Nature 2012
18

Understanding the Physiology of FGF21.
Ffolliott Martin Fisher, Eleftheria Maratos-Flier. Annu Rev Physiol 2016
381
17

FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response.
Matthew J Potthoff, Takeshi Inagaki, Santhosh Satapati, Xunshan Ding, Tianteng He, Regina Goetz, Moosa Mohammadi, Brian N Finck, David J Mangelsdorf, Steven A Kliewer,[...]. Proc Natl Acad Sci U S A 2009
481
16

Brown adipose tissue: function and physiological significance.
Barbara Cannon, Jan Nedergaard. Physiol Rev 2004
16

Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human.
Jun Wu, Pontus Boström, Lauren M Sparks, Li Ye, Jang Hyun Choi, An-Hoa Giang, Melin Khandekar, Kirsi A Virtanen, Pirjo Nuutila, Gert Schaart,[...]. Cell 2012
16

FGF21 acts centrally to induce sympathetic nerve activity, energy expenditure, and weight loss.
Bryn M Owen, Xunshan Ding, Donald A Morgan, Katie Colbert Coate, Angie L Bookout, Kamal Rahmouni, Steven A Kliewer, David J Mangelsdorf. Cell Metab 2014
305
15

Fibroblast growth factor 21 corrects obesity in mice.
Tamer Coskun, Holly A Bina, Michael A Schneider, James D Dunbar, Charlie C Hu, Yanyun Chen, David E Moller, Alexei Kharitonenkov. Endocrinology 2008
729
14

Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice.
Jing Xu, David J Lloyd, Clarence Hale, Shanaka Stanislaus, Michelle Chen, Glenn Sivits, Steven Vonderfecht, Randy Hecht, Yue-Sheng Li, Richard A Lindberg,[...]. Diabetes 2009
797
14


Identification and importance of brown adipose tissue in adult humans.
Aaron M Cypess, Sanaz Lehman, Gethin Williams, Ilan Tal, Dean Rodman, Allison B Goldfine, Frank C Kuo, Edwin L Palmer, Yu-Hua Tseng, Alessandro Doria,[...]. N Engl J Med 2009
14

FGF21 is an endocrine signal of protein restriction.
Thomas Laeger, Tara M Henagan, Diana C Albarado, Leanne M Redman, George A Bray, Robert C Noland, Heike Münzberg, Susan M Hutson, Thomas W Gettys, Michael W Schwartz,[...]. J Clin Invest 2014
332
13

FGF21 Regulates Metabolism Through Adipose-Dependent and -Independent Mechanisms.
Lucas D BonDurant, Magdalene Ameka, Meghan C Naber, Kathleen R Markan, Sharon O Idiga, Michael R Acevedo, Susan A Walsh, David M Ornitz, Matthew J Potthoff. Cell Metab 2017
152
13

Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans.
Paul Lee, Joyce D Linderman, Sheila Smith, Robert J Brychta, Juan Wang, Christopher Idelson, Rachel M Perron, Charlotte D Werner, Giao Q Phan, Udai S Kammula,[...]. Cell Metab 2014
497
12

Obesity is a fibroblast growth factor 21 (FGF21)-resistant state.
Ffolliott M Fisher, Patricia C Chui, Patrick J Antonellis, Holly A Bina, Alexei Kharitonenkov, Jeffrey S Flier, Eleftheria Maratos-Flier. Diabetes 2010
512
12

Fibroblast growth factor-21 regulates PPARγ activity and the antidiabetic actions of thiazolidinediones.
Paul A Dutchak, Takeshi Katafuchi, Angie L Bookout, Jang Hyun Choi, Ruth T Yu, David J Mangelsdorf, Steven A Kliewer. Cell 2012
391
11

FGF21 Mediates Endocrine Control of Simple Sugar Intake and Sweet Taste Preference by the Liver.
Stephanie von Holstein-Rathlou, Lucas D BonDurant, Lila Peltekian, Meghan C Naber, Terry C Yin, Kristin E Claflin, Adriana Ibarra Urizar, Andreas N Madsen, Cecilia Ratner, Birgitte Holst,[...]. Cell Metab 2016
200
11

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice.
Patrick Seale, Heather M Conroe, Jennifer Estall, Shingo Kajimura, Andrea Frontini, Jeff Ishibashi, Paul Cohen, Saverio Cinti, Bruce M Spiegelman. J Clin Invest 2011
835
11

FGF21 maintains glucose homeostasis by mediating the cross talk between liver and brain during prolonged fasting.
Qingning Liang, Ling Zhong, Jialiang Zhang, Yu Wang, Stefan R Bornstein, Chris R Triggle, Hong Ding, Karen S L Lam, Aimin Xu. Diabetes 2014
163
10

Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans.
Xinmei Zhang, Dennis C Y Yeung, Michal Karpisek, David Stejskal, Zhi-Guang Zhou, Feng Liu, Rachel L C Wong, Wing-Sun Chow, Annette W K Tso, Karen S L Lam,[...]. Diabetes 2008
624
10

FGF21 regulates metabolism and circadian behavior by acting on the nervous system.
Angie L Bookout, Marleen H M de Groot, Bryn M Owen, Syann Lee, Laurent Gautron, Heather L Lawrence, Xunshan Ding, Joel K Elmquist, Joseph S Takahashi, David J Mangelsdorf,[...]. Nat Med 2013
334
10

BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions.
Andrew J Whittle, Stefania Carobbio, Luís Martins, Marc Slawik, Elayne Hondares, María Jesús Vázquez, Donald Morgan, Robert I Csikasz, Rosalía Gallego, Sergio Rodriguez-Cuenca,[...]. Cell 2012
402
10

Brown adipose tissue responds to cold and adrenergic stimulation by induction of FGF21.
Dionysios V Chartoumpekis, Ioannis G Habeos, Panos G Ziros, Agathoklis I Psyrogiannis, Venetsana E Kyriazopoulou, Athanasios G Papavassiliou. Mol Med 2011
168
10

Brown adipose tissue regulates glucose homeostasis and insulin sensitivity.
Kristin I Stanford, Roeland J W Middelbeek, Kristy L Townsend, Ding An, Eva B Nygaard, Kristen M Hitchcox, Kathleen R Markan, Kazuhiro Nakano, Michael F Hirshman, Yu-Hua Tseng,[...]. J Clin Invest 2013
703
10



Recruited brown adipose tissue as an antiobesity agent in humans.
Takeshi Yoneshiro, Sayuri Aita, Mami Matsushita, Takashi Kayahara, Toshimitsu Kameya, Yuko Kawai, Toshihiko Iwanaga, Masayuki Saito. J Clin Invest 2013
596
10

PRDM16 controls a brown fat/skeletal muscle switch.
Patrick Seale, Bryan Bjork, Wenli Yang, Shingo Kajimura, Sherry Chin, Shihuan Kuang, Anthony Scimè, Srikripa Devarakonda, Heather M Conroe, Hediye Erdjument-Bromage,[...]. Nature 2008
10

A Long-Acting FGF21 Molecule, PF-05231023, Decreases Body Weight and Improves Lipid Profile in Non-human Primates and Type 2 Diabetic Subjects.
Saswata Talukdar, Yingjiang Zhou, Dongmei Li, Michelle Rossulek, Jennifer Dong, Veena Somayaji, Yan Weng, Ronald Clark, Adhiraj Lanba, Bryn M Owen,[...]. Cell Metab 2016
266
10

Research resource: Comprehensive expression atlas of the fibroblast growth factor system in adult mouse.
Klementina Fon Tacer, Angie L Bookout, Xunshan Ding, Hiroshi Kurosu, George B John, Lei Wang, Regina Goetz, Moosa Mohammadi, Makoto Kuro-o, David J Mangelsdorf,[...]. Mol Endocrinol 2010
450
10

Adiponectin mediates the metabolic effects of FGF21 on glucose homeostasis and insulin sensitivity in mice.
Zhuofeng Lin, Haishan Tian, Karen S L Lam, Shaoqiang Lin, Ruby C L Hoo, Morichika Konishi, Nobuyuki Itoh, Yu Wang, Stefan R Bornstein, Aimin Xu,[...]. Cell Metab 2013
394
9

The breadth of FGF21's metabolic actions are governed by FGFR1 in adipose tissue.
Andrew C Adams, Chaofeng Yang, Tamer Coskun, Christine C Cheng, Ruth E Gimeno, Yongde Luo, Alexei Kharitonenkov. Mol Metab 2012
196
9

Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine.
Kook Hwan Kim, Yeon Taek Jeong, Hyunhee Oh, Seong Hun Kim, Jae Min Cho, Yo-Na Kim, Su Sung Kim, Do Hoon Kim, Kyu Yeon Hur, Hyoung Kyu Kim,[...]. Nat Med 2013
529
9

Glucose induces FGF21 mRNA expression through ChREBP activation in rat hepatocytes.
Katsumi Iizuka, Jun Takeda, Yukio Horikawa. FEBS Lett 2009
134
9

FGF21 Regulates Sweet and Alcohol Preference.
Saswata Talukdar, Bryn M Owen, Parkyong Song, Genaro Hernandez, Yuan Zhang, Yingjiang Zhou, William T Scott, Bhavna Paratala, Tod Turner, Andrew Smith,[...]. Cell Metab 2016
180
9

FGF21 Signals Protein Status to the Brain and Adaptively Regulates Food Choice and Metabolism.
Cristal M Hill, Thomas Laeger, Madeleine Dehner, Diana C Albarado, Blaise Clarke, Desiree Wanders, Susan J Burke, J Jason Collier, Emily Qualls-Creekmore, Samantha M Solon-Biet,[...]. Cell Rep 2019
76
11

A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis.
P Puigserver, Z Wu, C W Park, R Graves, M Wright, B M Spiegelman. Cell 1998
9

Increased fibroblast growth factor 21 in obesity and nonalcoholic fatty liver disease.
Jody Dushay, Patricia C Chui, Gosala S Gopalakrishnan, Marta Varela-Rey, Meghan Crawley, Ffolliott M Fisher, Michael K Badman, Maria L Martinez-Chantar, Eleftheria Maratos-Flier. Gastroenterology 2010
408
9

The effects of LY2405319, an FGF21 analog, in obese human subjects with type 2 diabetes.
Gregory Gaich, Jenny Y Chien, Haoda Fu, Leonard C Glass, Mark A Deeg, William L Holland, Alexei Kharitonenkov, Thomas Bumol, Holger K Schilske, David E Moller. Cell Metab 2013
571
9

Liver Derived FGF21 Maintains Core Body Temperature During Acute Cold Exposure.
Magdalene Ameka, Kathleen R Markan, Donald A Morgan, Lucas D BonDurant, Sharon O Idiga, Meghan C Naber, Zhiyong Zhu, Leonid V Zingman, Justin L Grobe, Kamal Rahmouni,[...]. Sci Rep 2019
40
22

Identification of a novel FGF, FGF-21, preferentially expressed in the liver.
T Nishimura, Y Nakatake, M Konishi, N Itoh. Biochim Biophys Acta 2000
571
8

An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice.
William L Holland, Andrew C Adams, Joseph T Brozinick, Hai H Bui, Yukiko Miyauchi, Christine M Kusminski, Steven M Bauer, Mark Wade, Esha Singhal, Christine C Cheng,[...]. Cell Metab 2013
355
8

The circulating metabolic regulator FGF21 is induced by prolonged fasting and PPARalpha activation in man.
Cecilia Gälman, Tomas Lundåsen, Alexei Kharitonenkov, Holly A Bina, Mats Eriksson, Ingiäld Hafström, Maria Dahlin, Per Amark, Bo Angelin, Mats Rudling. Cell Metab 2008
376
8

FGF21 Is a Sugar-Induced Hormone Associated with Sweet Intake and Preference in Humans.
Susanna Søberg, Camilla H Sandholt, Naja Z Jespersen, Ulla Toft, Anja L Madsen, Stephanie von Holstein-Rathlou, Trisha J Grevengoed, Karl B Christensen, Wender L P Bredie, Matthew J Potthoff,[...]. Cell Metab 2017
113
8

FGF21 Is an Exocrine Pancreas Secretagogue.
Katie C Coate, Genaro Hernandez, Curtis A Thorne, Shengyi Sun, Thao D V Le, Kevin Vale, Steven A Kliewer, David J Mangelsdorf. Cell Metab 2017
59
13

Metabolic Responses to Dietary Protein Restriction Require an Increase in FGF21 that Is Delayed by the Absence of GCN2.
Thomas Laeger, Diana C Albarado, Susan J Burke, Lexus Trosclair, John W Hedgepeth, Hans-Rudolf Berthoud, Thomas W Gettys, J Jason Collier, Heike Münzberg, Christopher D Morrison. Cell Rep 2016
112
8


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.