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Times Cited: 198
Times Cited: 198
Times Cited
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A mouse model of the most aggressive subgroup of human medulloblastoma.
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Molecular subgroups of medulloblastoma: the current consensus.
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Michael D Taylor, Paul A Northcott, Andrey Korshunov, Marc Remke, Yoon-Jae Cho, Steven C Clifford, Charles G Eberhart, D Williams Parsons, Stefan Rutkowski, Amar Gajjar,[...]. Acta Neuropathol 2012
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Intertumoral Heterogeneity within Medulloblastoma Subgroups.
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Medulloblastoma comprises four distinct molecular variants.
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Subtypes of medulloblastoma have distinct developmental origins.
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Subgroup-specific structural variation across 1,000 medulloblastoma genomes.
Paul A Northcott, David J H Shih, John Peacock, Livia Garzia, A Sorana Morrissy, Thomas Zichner, Adrian M Stütz, Andrey Korshunov, Jüri Reimand, Steven E Schumacher,[...]. Nature 2012
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Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome.
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Novel mutations target distinct subgroups of medulloblastoma.
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The whole-genome landscape of medulloblastoma subtypes.
Paul A Northcott, Ivo Buchhalter, A Sorana Morrissy, Volker Hovestadt, Joachim Weischenfeldt, Tobias Ehrenberger, Susanne Gröbner, Maia Segura-Wang, Thomas Zichner, Vasilisa A Rudneva,[...]. Nature 2017
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Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma.
Paul A Northcott, Catherine Lee, Thomas Zichner, Adrian M Stütz, Serap Erkek, Daisuke Kawauchi, David J H Shih, Volker Hovestadt, Marc Zapatka, Dominik Sturm,[...]. Nature 2014
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Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas.
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Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma.
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Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells.
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Dissecting the genomic complexity underlying medulloblastoma.
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HDAC and PI3K Antagonists Cooperate to Inhibit Growth of MYC-Driven Medulloblastoma.
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Yanxin Pei, Kun-Wei Liu, Jun Wang, Alexandra Garancher, Ran Tao, Lourdes A Esparza, Donna L Maier, Yoko T Udaka, Najiba Murad, Sorana Morrissy,[...]. Cancer Cell 2016
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Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition.
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Combined MYC and P53 defects emerge at medulloblastoma relapse and define rapidly progressive, therapeutically targetable disease.
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Medulloblastomics: the end of the beginning.
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Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features.
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Active medulloblastoma enhancers reveal subgroup-specific cellular origins.
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Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma.
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Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations.
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Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study.
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Pleiotropic role for MYCN in medulloblastoma.
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Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations.
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Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells.
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Cytogenetic prognostication within medulloblastoma subgroups.
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Divergent clonal selection dominates medulloblastoma at recurrence.
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Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC.
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Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis.
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Medulloblastoma Genotype Dictates Blood Brain Barrier Phenotype.
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HD-MB03 is a novel Group 3 medulloblastoma model demonstrating sensitivity to histone deacetylase inhibitor treatment.
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Aberrant ERBB4-SRC Signaling as a Hallmark of Group 4 Medulloblastoma Revealed by Integrative Phosphoproteomic Profiling.
Antoine Forget, Loredana Martignetti, Stéphanie Puget, Laurence Calzone, Sebastian Brabetz, Daniel Picard, Arnau Montagud, Stéphane Liva, Alexandre Sta, Florent Dingli,[...]. Cancer Cell 2018
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Inactivation of Ezh2 Upregulates Gfi1 and Drives Aggressive Myc-Driven Group 3 Medulloblastoma.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.