A citation-based method for searching scientific literature

Atsuhiko Ichimura, Akira Hirasawa, Odile Poulain-Godefroy, Amélie Bonnefond, Takafumi Hara, Loïc Yengo, Ikuo Kimura, Audrey Leloire, Ning Liu, Keiko Iida, Hélène Choquet, Philippe Besnard, Cécile Lecoeur, Sidonie Vivequin, Kumiko Ayukawa, Masato Takeuchi, Kentaro Ozawa, Maithé Tauber, Claudio Maffeis, Anita Morandi, Raffaella Buzzetti, Paul Elliott, Anneli Pouta, Marjo-Riitta Jarvelin, Antje Körner, Wieland Kiess, Marie Pigeyre, Roberto Caiazzo, Wim Van Hul, Luc Van Gaal, Fritz Horber, Beverley Balkau, Claire Lévy-Marchal, Konstantinos Rouskas, Anastasia Kouvatsi, Johannes Hebebrand, Anke Hinney, Andre Scherag, François Pattou, David Meyre, Taka-aki Koshimizu, Isabelle Wolowczuk, Gozoh Tsujimoto, Philippe Froguel. Nature 2012
Times Cited: 445







List of co-cited articles
792 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects.
Da Young Oh, Saswata Talukdar, Eun Ju Bae, Takeshi Imamura, Hidetaka Morinaga, WuQiang Fan, Pingping Li, Wendell J Lu, Steven M Watkins, Jerrold M Olefsky. Cell 2010
58

Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120.
Akira Hirasawa, Keiko Tsumaya, Takeo Awaji, Susumu Katsuma, Tetsuya Adachi, Masateru Yamada, Yukihiko Sugimoto, Shunichi Miyazaki, Gozoh Tsujimoto. Nat Med 2005
48

A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice.
Da Young Oh, Evelyn Walenta, Taro E Akiyama, William S Lagakos, Denise Lackey, Ariane R Pessentheiner, Roman Sasik, Nasun Hah, Tyler J Chi, Jason M Cox,[...]. Nat Med 2014
240
33

The regulation of adipogenesis through GPR120.
Chizu Gotoh, Yeon-Hee Hong, Tomoyo Iga, Daisuke Hishikawa, Yasuki Suzuki, Sang-Houn Song, Ki-Choon Choi, Tetsuya Adachi, Akira Hirasawa, Gozoh Tsujimoto,[...]. Biochem Biophys Res Commun 2007
179
26

The lipid sensor GPR120 promotes brown fat activation and FGF21 release from adipocytes.
Tania Quesada-López, Rubén Cereijo, Jean-Valery Turatsinze, Anna Planavila, Montserrat Cairó, Aleix Gavaldà-Navarro, Marion Peyrou, Ricardo Moure, Roser Iglesias, Marta Giralt,[...]. Nat Commun 2016
121
21

The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat.
Maaike Schilperoort, Andrea D van Dam, Geerte Hoeke, Irina G Shabalina, Anthony Okolo, Aylin C Hanyaloglu, Lea H Dib, Isabel M Mol, Natarin Caengprasath, Yi-Wah Chan,[...]. EMBO Mol Med 2018
46
45

Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.
Yasuaki Itoh, Yuji Kawamata, Masataka Harada, Makoto Kobayashi, Ryo Fujii, Shoji Fukusumi, Kazuhiro Ogi, Masaki Hosoya, Yasuhiro Tanaka, Hiroshi Uejima,[...]. Nature 2003
20

The pharmacology of TUG-891, a potent and selective agonist of the free fatty acid receptor 4 (FFA4/GPR120), demonstrates both potential opportunity and possible challenges to therapeutic agonism.
Brian D Hudson, Bharat Shimpukade, Amanda E Mackenzie, Adrian J Butcher, John D Pediani, Elisabeth Christiansen, Helen Heathcote, Andrew B Tobin, Trond Ulven, Graeme Milligan. Mol Pharmacol 2013
140
17

GPR120 (FFAR4) is preferentially expressed in pancreatic delta cells and regulates somatostatin secretion from murine islets of Langerhans.
Virginia M Stone, Shalinee Dhayal, Katy J Brocklehurst, Carol Lenaghan, Maria Sörhede Winzell, Mårten Hammar, Xiufeng Xu, David M Smith, Noel G Morgan. Diabetologia 2014
90
17

Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells.
Maja S Engelstoft, Won-Mee Park, Ichiro Sakata, Line V Kristensen, Anna Sofie Husted, Sherri Osborne-Lawrence, Paul K Piper, Angela K Walker, Maria H Pedersen, Mark K Nøhr,[...]. Mol Metab 2013
212
15

Free Fatty Acid Receptors in Health and Disease.
Ikuo Kimura, Atsuhiko Ichimura, Ryuji Ohue-Kitano, Miki Igarashi. Physiol Rev 2020
171
15

The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids.
Celia P Briscoe, Mohammad Tadayyon, John L Andrews, William G Benson, Jon K Chambers, Michelle M Eilert, Catherine Ellis, Nabil A Elshourbagy, Aaron S Goetz, Dana T Minnick,[...]. J Biol Chem 2003
818
14

Free fatty acids induce cholecystokinin secretion through GPR120.
Toshiki Tanaka, Susumu Katsuma, Tetsuya Adachi, Taka-aki Koshimizu, Akira Hirasawa, Gozoh Tsujimoto. Naunyn Schmiedebergs Arch Pharmacol 2008
198
13


Alteration of the glucagon axis in GPR120 (FFAR4) knockout mice: a role for GPR120 in glucagon secretion.
Arthur T Suckow, David Polidori, Wen Yan, Suhyoun Chon, Jing Ying Ma, James Leonard, Celia P Briscoe. J Biol Chem 2014
59
20

Differential signaling by splice variants of the human free fatty acid receptor GPR120.
Sarah-Jane Watson, Alastair J H Brown, Nicholas D Holliday. Mol Pharmacol 2012
101
11

The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse.
Pär Steneberg, Nir Rubins, Reut Bartoov-Shifman, Michael D Walker, Helena Edlund. Cell Metab 2005
326
11

FFA4/GPR120: Pharmacology and Therapeutic Opportunities.
Graeme Milligan, Elisa Alvarez-Curto, Brian D Hudson, Rudi Prihandoko, Andrew B Tobin. Trends Pharmacol Sci 2017
53
20

Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis.
Keren I Hilgendorf, Carl T Johnson, Anja Mezger, Selena L Rice, Alessandra M Norris, Janos Demeter, William J Greenleaf, Jeremy F Reiter, Daniel Kopinke, Peter K Jackson. Cell 2019
73
15

Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2.
Gwen Tolhurst, Helen Heffron, Yu Shan Lam, Helen E Parker, Abdella M Habib, Eleftheria Diakogiannaki, Jennifer Cameron, Johannes Grosse, Frank Reimann, Fiona M Gribble. Diabetes 2012
10

Discovery of a potent and selective GPR120 agonist.
Bharat Shimpukade, Brian D Hudson, Christine Kiel Hovgaard, Graeme Milligan, Trond Ulven. J Med Chem 2012
119
10

The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43.
Ikuo Kimura, Kentaro Ozawa, Daisuke Inoue, Takeshi Imamura, Kumi Kimura, Takeshi Maeda, Kazuya Terasawa, Daiji Kashihara, Kanako Hirano, Taeko Tani,[...]. Nat Commun 2013
711
10


Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases.
Saswata Talukdar, Jerrold M Olefsky, Olivia Osborn. Trends Pharmacol Sci 2011
180
10

Complex Pharmacology of Free Fatty Acid Receptors.
Graeme Milligan, Bharat Shimpukade, Trond Ulven, Brian D Hudson. Chem Rev 2017
124
9

Central Agonism of GPR120 Acutely Inhibits Food Intake and Food Reward and Chronically Suppresses Anxiety-Like Behavior in Mice.
Stéphanie Auguste, Alexandre Fisette, Maria F Fernandes, Cécile Hryhorczuk, Vincent Poitout, Thierry Alquier, Stephanie Fulton. Int J Neuropsychopharmacol 2016
31
29

Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes.
Cong Tang, Kashan Ahmed, Andreas Gille, Shun Lu, Hermann-Josef Gröne, Sorin Tunaru, Stefan Offermanns. Nat Med 2015
181
9

Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules.
Celia P Briscoe, Andrew J Peat, Stephen C McKeown, David F Corbett, Aaron S Goetz, Thomas R Littleton, David C McCoy, Terry P Kenakin, John L Andrews, Carina Ammala,[...]. Br J Pharmacol 2006
324
9

GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo.
Martin G Latour, Thierry Alquier, Elizabeth Oseid, Caroline Tremblay, Thomas L Jetton, Jian Luo, Daniel C-H Lin, Vincent Poitout. Diabetes 2007
209
9

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.
Andrew J Brown, Susan M Goldsworthy, Ashley A Barnes, Michelle M Eilert, Lili Tcheang, Dion Daniels, Alison I Muir, Mark J Wigglesworth, Ian Kinghorn, Neil J Fraser,[...]. J Biol Chem 2003
9

Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120).
Steven M Sparks, Grace Chen, Jon L Collins, Dana Danger, Steven T Dock, Channa Jayawickreme, Stephen Jenkinson, Christopher Laudeman, M Anthony Leesnitzer, Xi Liang,[...]. Bioorg Med Chem Lett 2014
81
11

G protein-coupled receptor 120 signaling regulates ghrelin secretion in vivo and in vitro.
Zhi Gong, Makoto Yoshimura, Sayaka Aizawa, Reiko Kurotani, Jeffrey M Zigman, Takafumi Sakai, Ichiro Sakata. Am J Physiol Endocrinol Metab 2014
60
15


Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation.
Nathalia R V Dragano, Carina Solon, Albina F Ramalho, Rodrigo F de Moura, Daniela S Razolli, Elisabeth Christiansen, Carlos Azevedo, Trond Ulven, Licio A Velloso. J Neuroinflammation 2017
73
10

Free fatty acid receptors as therapeutic targets for the treatment of diabetes.
Atsuhiko Ichimura, Sae Hasegawa, Mayu Kasubuchi, Ikuo Kimura. Front Pharmacol 2014
96
8

Eicosapentaenoic acid shows anti-inflammatory effect via GPR120 in 3T3-L1 adipocytes and attenuates adipose tissue inflammation in diet-induced obese mice.
Hodaka Yamada, Tomio Umemoto, Masafumi Kakei, Shin-Ichi Momomura, Masanobu Kawakami, San-E Ishikawa, Kazuo Hara. Nutr Metab (Lond) 2017
35
22

A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.
Jalal Taneera, Stefan Lang, Amitabh Sharma, Joao Fadista, Yuedan Zhou, Emma Ahlqvist, Anna Jonsson, Valeriya Lyssenko, Petter Vikman, Ola Hansson,[...]. Cell Metab 2012
248
8

The acute glucose lowering effect of specific GPR120 activation in mice is mainly driven by glucagon-like peptide 1.
Linda Sundström, Susanna Myhre, Monika Sundqvist, Andrea Ahnmark, William McCoull, Piotr Raubo, Sam D Groombridge, Magnus Polla, Ann-Christin Nyström, Lisbeth Kristensson,[...]. PLoS One 2017
25
32

Improved glucose control and reduced body fat mass in free fatty acid receptor 2-deficient mice fed a high-fat diet.
Mikael Bjursell, Therése Admyre, Melker Göransson, Anna E Marley, David M Smith, Jan Oscarsson, Mohammad Bohlooly-Y. Am J Physiol Endocrinol Metab 2011
195
8

The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding.
Melkam Kebede, Thierry Alquier, Martin G Latour, Meriem Semache, Caroline Tremblay, Vincent Poitout. Diabetes 2008
133
8

Structure-activity relationships of GPR120 agonists based on a docking simulation.
Qi Sun, Akira Hirasawa, Takafumi Hara, Ikuo Kimura, Tetsuya Adachi, Takeo Awaji, Masaji Ishiguro, Takayoshi Suzuki, Naoki Miyata, Gozoh Tsujimoto. Mol Pharmacol 2010
76
10

Non-Acidic Free Fatty Acid Receptor 4 Agonists with Antidiabetic Activity.
Carlos M G Azevedo, Kenneth R Watterson, Ed T Wargent, Steffen V F Hansen, Brian D Hudson, Małgorzata A Kępczyńska, Julia Dunlop, Bharat Shimpukade, Elisabeth Christiansen, Graeme Milligan,[...]. J Med Chem 2016
52
15

GPR120 promotes adipogenesis through intracellular calcium and extracellular signal-regulated kinase 1/2 signal pathway.
Tongxing Song, Yuanfei Zhou, Jian Peng, Ya-Xiong Tao, Yang Yang, Tao Xu, Jie Peng, Jiao Ren, Quanhang Xiang, Hongkui Wei. Mol Cell Endocrinol 2016
30
26

Evaluation of the insulin-releasing and glucose-lowering effects of GPR120 activation in pancreatic β-cells.
B M Moran, Y H A Abdel-Wahab, P R Flatt, A M McKillop. Diabetes Obes Metab 2014
38
21

Activity of dietary fatty acids on FFA1 and FFA4 and characterisation of pinolenic acid as a dual FFA1/FFA4 agonist with potential effect against metabolic diseases.
Elisabeth Christiansen, Kenneth R Watterson, Claire J Stocker, Elena Sokol, Laura Jenkins, Katharina Simon, Manuel Grundmann, Rasmus K Petersen, Edward T Wargent, Brian D Hudson,[...]. Br J Nutr 2015
65
12

GPR120 on Kupffer cells mediates hepatoprotective effects of ω3-fatty acids.
Dimitri Aristotle Raptis, Perparim Limani, Jae Hwi Jang, Udo Ungethüm, Christoph Tschuor, Rolf Graf, Bostjan Humar, Pierre-Alain Clavien. J Hepatol 2014
75
10

Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects.
Mark M Yore, Ismail Syed, Pedro M Moraes-Vieira, Tejia Zhang, Mark A Herman, Edwin A Homan, Rajesh T Patel, Jennifer Lee, Shili Chen, Odile D Peroni,[...]. Cell 2014
423
8

Long-Chain Free Fatty Acid Receptor GPR120 Mediates Oil-Induced GIP Secretion Through CCK in Male Mice.
Akiko Sankoda, Norio Harada, Kanako Iwasaki, Shunsuke Yamane, Yuki Murata, Kimitaka Shibue, Yotsapon Thewjitcharoen, Kazuyo Suzuki, Takanari Harada, Yoshinori Kanemaru,[...]. Endocrinology 2017
31
22


Taste preference for fatty acids is mediated by GPR40 and GPR120.
Cristina Cartoni, Keiko Yasumatsu, Tadahiro Ohkuri, Noriatsu Shigemura, Ryusuke Yoshida, Nicolas Godinot, Johannes le Coutre, Yuzo Ninomiya, Sami Damak. J Neurosci 2010
261
7


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.