Marco Gerlinger, Andrew J Rowan, Stuart Horswell, M Math, James Larkin, David Endesfelder, Eva Gronroos, Pierre Martinez, Nicholas Matthews, Aengus Stewart, Patrick Tarpey, Ignacio Varela, Benjamin Phillimore, Sharmin Begum, Neil Q McDonald, Adam Butler, David Jones, Keiran Raine, Calli Latimer, Claudio R Santos, Mahrokh Nohadani, Aron C Eklund, Bradley Spencer-Dene, Graham Clark, Lisa Pickering, Gordon Stamp, Martin Gore, Zoltan Szallasi, Julian Downward, P Andrew Futreal, Charles Swanton. N Engl J Med 2012
Times Cited: 5089
Times Cited: 5089
Times Cited
Times Co-cited
Similarity
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
11
Tracking the Evolution of Non-Small-Cell Lung Cancer.
Mariam Jamal-Hanjani, Gareth A Wilson, Nicholas McGranahan, Nicolai J Birkbak, Thomas B K Watkins, Selvaraju Veeriah, Seema Shafi, Diana H Johnson, Richard Mitter, Rachel Rosenthal,[...]. N Engl J Med 2017
Mariam Jamal-Hanjani, Gareth A Wilson, Nicholas McGranahan, Nicolai J Birkbak, Thomas B K Watkins, Selvaraju Veeriah, Seema Shafi, Diana H Johnson, Richard Mitter, Rachel Rosenthal,[...]. N Engl J Med 2017
11
Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal.
Samra Turajlic, Hang Xu, Kevin Litchfield, Andrew Rowan, Tim Chambers, Jose I Lopez, David Nicol, Tim O'Brien, James Larkin, Stuart Horswell,[...]. Cell 2018
Samra Turajlic, Hang Xu, Kevin Litchfield, Andrew Rowan, Tim Chambers, Jose I Lopez, David Nicol, Tim O'Brien, James Larkin, Stuart Horswell,[...]. Cell 2018
10
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future.
Nicholas McGranahan, Charles Swanton. Cell 2017
Nicholas McGranahan, Charles Swanton. Cell 2017
10
Distant metastasis occurs late during the genetic evolution of pancreatic cancer.
Shinichi Yachida, Siân Jones, Ivana Bozic, Tibor Antal, Rebecca Leary, Baojin Fu, Mihoko Kamiyama, Ralph H Hruban, James R Eshleman, Martin A Nowak,[...]. Nature 2010
Shinichi Yachida, Siân Jones, Ivana Bozic, Tibor Antal, Rebecca Leary, Baojin Fu, Mihoko Kamiyama, Ralph H Hruban, James R Eshleman, Martin A Nowak,[...]. Nature 2010
10
Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal.
Samra Turajlic, Hang Xu, Kevin Litchfield, Andrew Rowan, Stuart Horswell, Tim Chambers, Tim O'Brien, Jose I Lopez, Thomas B K Watkins, David Nicol,[...]. Cell 2018
Samra Turajlic, Hang Xu, Kevin Litchfield, Andrew Rowan, Stuart Horswell, Tim Chambers, Tim O'Brien, Jose I Lopez, Thomas B K Watkins, David Nicol,[...]. Cell 2018
9
Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing.
Marco Gerlinger, Stuart Horswell, James Larkin, Andrew J Rowan, Max P Salm, Ignacio Varela, Rosalie Fisher, Nicholas McGranahan, Nicholas Matthews, Claudio R Santos,[...]. Nat Genet 2014
Marco Gerlinger, Stuart Horswell, James Larkin, Andrew J Rowan, Max P Salm, Ignacio Varela, Rosalie Fisher, Nicholas McGranahan, Nicholas Matthews, Claudio R Santos,[...]. Nat Genet 2014
8
Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma.
Robert J Motzer, Nizar M Tannir, David F McDermott, Osvaldo Arén Frontera, Bohuslav Melichar, Toni K Choueiri, Elizabeth R Plimack, Philippe Barthélémy, Camillo Porta, Saby George,[...]. N Engl J Med 2018
Robert J Motzer, Nizar M Tannir, David F McDermott, Osvaldo Arén Frontera, Bohuslav Melichar, Toni K Choueiri, Elizabeth R Plimack, Philippe Barthélémy, Camillo Porta, Saby George,[...]. N Engl J Med 2018
7
Pembrolizumab plus Axitinib versus Sunitinib for Advanced Renal-Cell Carcinoma.
Brian I Rini, Elizabeth R Plimack, Viktor Stus, Rustem Gafanov, Robert Hawkins, Dmitry Nosov, Frédéric Pouliot, Boris Alekseev, Denis Soulières, Bohuslav Melichar,[...]. N Engl J Med 2019
Brian I Rini, Elizabeth R Plimack, Viktor Stus, Rustem Gafanov, Robert Hawkins, Dmitry Nosov, Frédéric Pouliot, Boris Alekseev, Denis Soulières, Bohuslav Melichar,[...]. N Engl J Med 2019
7
7
Detection of circulating tumor DNA in early- and late-stage human malignancies.
Chetan Bettegowda, Mark Sausen, Rebecca J Leary, Isaac Kinde, Yuxuan Wang, Nishant Agrawal, Bjarne R Bartlett, Hao Wang, Brandon Luber, Rhoda M Alani,[...]. Sci Transl Med 2014
Chetan Bettegowda, Mark Sausen, Rebecca J Leary, Isaac Kinde, Yuxuan Wang, Nishant Agrawal, Bjarne R Bartlett, Hao Wang, Brandon Luber, Rhoda M Alani,[...]. Sci Transl Med 2014
7
Tumour evolution inferred by single-cell sequencing.
Nicholas Navin, Jude Kendall, Jennifer Troge, Peter Andrews, Linda Rodgers, Jeanne McIndoo, Kerry Cook, Asya Stepansky, Dan Levy, Diane Esposito,[...]. Nature 2011
Nicholas Navin, Jude Kendall, Jennifer Troge, Peter Andrews, Linda Rodgers, Jeanne McIndoo, Kerry Cook, Asya Stepansky, Dan Levy, Diane Esposito,[...]. Nature 2011
6
Cancer statistics, 2020.
Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal. CA Cancer J Clin 2020
Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal. CA Cancer J Clin 2020
6
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.
Christopher Abbosh, Nicolai J Birkbak, Gareth A Wilson, Mariam Jamal-Hanjani, Tudor Constantin, Raheleh Salari, John Le Quesne, David A Moore, Selvaraju Veeriah, Rachel Rosenthal,[...]. Nature 2017
Christopher Abbosh, Nicolai J Birkbak, Gareth A Wilson, Mariam Jamal-Hanjani, Tudor Constantin, Raheleh Salari, John Le Quesne, David A Moore, Selvaraju Veeriah, Rachel Rosenthal,[...]. Nature 2017
6
Subclonal diversification of primary breast cancer revealed by multiregion sequencing.
Lucy R Yates, Moritz Gerstung, Stian Knappskog, Christine Desmedt, Gunes Gundem, Peter Van Loo, Turid Aas, Ludmil B Alexandrov, Denis Larsimont, Helen Davies,[...]. Nat Med 2015
Lucy R Yates, Moritz Gerstung, Stian Knappskog, Christine Desmedt, Gunes Gundem, Peter Van Loo, Turid Aas, Ludmil B Alexandrov, Denis Larsimont, Helen Davies,[...]. Nat Med 2015
6
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.
Hyuna Sung, Jacques Ferlay, Rebecca L Siegel, Mathieu Laversanne, Isabelle Soerjomataram, Ahmedin Jemal, Freddie Bray. CA Cancer J Clin 2021
Hyuna Sung, Jacques Ferlay, Rebecca L Siegel, Mathieu Laversanne, Isabelle Soerjomataram, Ahmedin Jemal, Freddie Bray. CA Cancer J Clin 2021
6
Avelumab plus Axitinib versus Sunitinib for Advanced Renal-Cell Carcinoma.
Robert J Motzer, Konstantin Penkov, John Haanen, Brian Rini, Laurence Albiges, Matthew T Campbell, Balaji Venugopal, Christian Kollmannsberger, Sylvie Negrier, Motohide Uemura,[...]. N Engl J Med 2019
Robert J Motzer, Konstantin Penkov, John Haanen, Brian Rini, Laurence Albiges, Matthew T Campbell, Balaji Venugopal, Christian Kollmannsberger, Sylvie Negrier, Motohide Uemura,[...]. N Engl J Med 2019
5
Emerging Biological Principles of Metastasis.
Arthur W Lambert, Diwakar R Pattabiraman, Robert A Weinberg. Cell 2017
Arthur W Lambert, Diwakar R Pattabiraman, Robert A Weinberg. Cell 2017
5
Identification of neutral tumor evolution across cancer types.
Marc J Williams, Benjamin Werner, Chris P Barnes, Trevor A Graham, Andrea Sottoriva. Nat Genet 2016
Marc J Williams, Benjamin Werner, Chris P Barnes, Trevor A Graham, Andrea Sottoriva. Nat Genet 2016
5
A Big Bang model of human colorectal tumor growth.
Andrea Sottoriva, Haeyoun Kang, Zhicheng Ma, Trevor A Graham, Matthew P Salomon, Junsong Zhao, Paul Marjoram, Kimberly Siegmund, Michael F Press, Darryl Shibata,[...]. Nat Genet 2015
Andrea Sottoriva, Haeyoun Kang, Zhicheng Ma, Trevor A Graham, Matthew P Salomon, Junsong Zhao, Paul Marjoram, Kimberly Siegmund, Michael F Press, Darryl Shibata,[...]. Nat Genet 2015
5
Signatures of mutational processes in human cancer.
Ludmil B Alexandrov, Serena Nik-Zainal, David C Wedge, Samuel A J R Aparicio, Sam Behjati, Andrew V Biankin, Graham R Bignell, Niccolò Bolli, Ake Borg, Anne-Lise Børresen-Dale,[...]. Nature 2013
Ludmil B Alexandrov, Serena Nik-Zainal, David C Wedge, Samuel A J R Aparicio, Sam Behjati, Andrew V Biankin, Graham R Bignell, Niccolò Bolli, Ake Borg, Anne-Lise Børresen-Dale,[...]. Nature 2013
5
Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing.
Jianjun Zhang, Junya Fujimoto, Jianhua Zhang, David C Wedge, Xingzhi Song, Jiexin Zhang, Sahil Seth, Chi-Wan Chow, Yu Cao, Curtis Gumbs,[...]. Science 2014
Jianjun Zhang, Junya Fujimoto, Jianhua Zhang, David C Wedge, Xingzhi Song, Jiexin Zhang, Sahil Seth, Chi-Wan Chow, Yu Cao, Curtis Gumbs,[...]. Science 2014
5
Radiomics: Images Are More than Pictures, They Are Data.
Robert J Gillies, Paul E Kinahan, Hedvig Hricak. Radiology 2016
Robert J Gillies, Paul E Kinahan, Hedvig Hricak. Radiology 2016
5
The patterns and dynamics of genomic instability in metastatic pancreatic cancer.
Peter J Campbell, Shinichi Yachida, Laura J Mudie, Philip J Stephens, Erin D Pleasance, Lucy A Stebbings, Laura A Morsberger, Calli Latimer, Stuart McLaren, Meng-Lay Lin,[...]. Nature 2010
Peter J Campbell, Shinichi Yachida, Laura J Mudie, Philip J Stephens, Erin D Pleasance, Lucy A Stebbings, Laura A Morsberger, Calli Latimer, Stuart McLaren, Meng-Lay Lin,[...]. Nature 2010
5
Tumour heterogeneity and resistance to cancer therapies.
Ibiayi Dagogo-Jack, Alice T Shaw. Nat Rev Clin Oncol 2018
Ibiayi Dagogo-Jack, Alice T Shaw. Nat Rev Clin Oncol 2018
5
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes.
Stefan C Dentro, Ignaty Leshchiner, Kerstin Haase, Maxime Tarabichi, Jeff Wintersinger, Amit G Deshwar, Kaixian Yu, Yulia Rubanova, Geoff Macintyre, Jonas Demeulemeester,[...]. Cell 2021
Stefan C Dentro, Ignaty Leshchiner, Kerstin Haase, Maxime Tarabichi, Jeff Wintersinger, Amit G Deshwar, Kaixian Yu, Yulia Rubanova, Geoff Macintyre, Jonas Demeulemeester,[...]. Cell 2021
8
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma.
Robert J Motzer, Thomas E Hutson, Piotr Tomczak, M Dror Michaelson, Ronald M Bukowski, Olivier Rixe, Stéphane Oudard, Sylvie Negrier, Cezary Szczylik, Sindy T Kim,[...]. N Engl J Med 2007
Robert J Motzer, Thomas E Hutson, Piotr Tomczak, M Dror Michaelson, Ronald M Bukowski, Olivier Rixe, Stéphane Oudard, Sylvie Negrier, Cezary Szczylik, Sindy T Kim,[...]. N Engl J Med 2007
4
The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs-Part A: Renal, Penile, and Testicular Tumours.
Holger Moch, Antonio L Cubilla, Peter A Humphrey, Victor E Reuter, Thomas M Ulbright. Eur Urol 2016
Holger Moch, Antonio L Cubilla, Peter A Humphrey, Victor E Reuter, Thomas M Ulbright. Eur Urol 2016
4
Systemic Therapy for Metastatic Renal-Cell Carcinoma.
Toni K Choueiri, Robert J Motzer. N Engl J Med 2017
Toni K Choueiri, Robert J Motzer. N Engl J Med 2017
4
Cancer as an evolutionary and ecological process.
Lauren M F Merlo, John W Pepper, Brian J Reid, Carlo C Maley. Nat Rev Cancer 2006
Lauren M F Merlo, John W Pepper, Brian J Reid, Carlo C Maley. Nat Rev Cancer 2006
4
Resolving genetic heterogeneity in cancer.
Samra Turajlic, Andrea Sottoriva, Trevor Graham, Charles Swanton. Nat Rev Genet 2019
Samra Turajlic, Andrea Sottoriva, Trevor Graham, Charles Swanton. Nat Rev Genet 2019
4
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma.
Anoop P Patel, Itay Tirosh, John J Trombetta, Alex K Shalek, Shawn M Gillespie, Hiroaki Wakimoto, Daniel P Cahill, Brian V Nahed, William T Curry, Robert L Martuza,[...]. Science 2014
Anoop P Patel, Itay Tirosh, John J Trombetta, Alex K Shalek, Shawn M Gillespie, Hiroaki Wakimoto, Daniel P Cahill, Brian V Nahed, William T Curry, Robert L Martuza,[...]. Science 2014
4
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer.
Sidharth V Puram, Itay Tirosh, Anuraag S Parikh, Anoop P Patel, Keren Yizhak, Shawn Gillespie, Christopher Rodman, Christina L Luo, Edmund A Mroz, Kevin S Emerick,[...]. Cell 2017
Sidharth V Puram, Itay Tirosh, Anuraag S Parikh, Anoop P Patel, Keren Yizhak, Shawn Gillespie, Christopher Rodman, Christina L Luo, Edmund A Mroz, Kevin S Emerick,[...]. Cell 2017
4
4
Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics.
Andrea Sottoriva, Inmaculada Spiteri, Sara G M Piccirillo, Anestis Touloumis, V Peter Collins, John C Marioni, Christina Curtis, Colin Watts, Simon Tavaré. Proc Natl Acad Sci U S A 2013
Andrea Sottoriva, Inmaculada Spiteri, Sara G M Piccirillo, Anestis Touloumis, V Peter Collins, John C Marioni, Christina Curtis, Colin Watts, Simon Tavaré. Proc Natl Acad Sci U S A 2013
4
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1.
David A Barbie, Pablo Tamayo, Jesse S Boehm, So Young Kim, Susan E Moody, Ian F Dunn, Anna C Schinzel, Peter Sandy, Etienne Meylan, Claudia Scholl,[...]. Nature 2009
David A Barbie, Pablo Tamayo, Jesse S Boehm, So Young Kim, Susan E Moody, Ian F Dunn, Anna C Schinzel, Peter Sandy, Etienne Meylan, Claudia Scholl,[...]. Nature 2009
4
Cancer heterogeneity: implications for targeted therapeutics.
R Fisher, L Pusztai, C Swanton. Br J Cancer 2013
R Fisher, L Pusztai, C Swanton. Br J Cancer 2013
4
Cancer Statistics, 2021.
Rebecca L Siegel, Kimberly D Miller, Hannah E Fuchs, Ahmedin Jemal. CA Cancer J Clin 2021
Rebecca L Siegel, Kimberly D Miller, Hannah E Fuchs, Ahmedin Jemal. CA Cancer J Clin 2021
4
Current and future perspectives of liquid biopsies in genomics-driven oncology.
Ellen Heitzer, Imran S Haque, Charles E S Roberts, Michael R Speicher. Nat Rev Genet 2019
Ellen Heitzer, Imran S Haque, Charles E S Roberts, Michael R Speicher. Nat Rev Genet 2019
4
Liquid biopsy: monitoring cancer-genetics in the blood.
Emily Crowley, Federica Di Nicolantonio, Fotios Loupakis, Alberto Bardelli. Nat Rev Clin Oncol 2013
Emily Crowley, Federica Di Nicolantonio, Fotios Loupakis, Alberto Bardelli. Nat Rev Clin Oncol 2013
4
Tumor Heterogeneity and Lesion-Specific Response to Targeted Therapy in Colorectal Cancer.
Mariangela Russo, Giulia Siravegna, Lawrence S Blaszkowsky, Giorgio Corti, Giovanni Crisafulli, Leanne G Ahronian, Benedetta Mussolin, Eunice L Kwak, Michela Buscarino, Luca Lazzari,[...]. Cancer Discov 2016
Mariangela Russo, Giulia Siravegna, Lawrence S Blaszkowsky, Giorgio Corti, Giovanni Crisafulli, Leanne G Ahronian, Benedetta Mussolin, Eunice L Kwak, Michela Buscarino, Luca Lazzari,[...]. Cancer Discov 2016
4
The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers.
Luis A Diaz, Richard T Williams, Jian Wu, Isaac Kinde, J Randolph Hecht, Jordan Berlin, Benjamin Allen, Ivana Bozic, Johannes G Reiter, Martin A Nowak,[...]. Nature 2012
Luis A Diaz, Richard T Williams, Jian Wu, Isaac Kinde, J Randolph Hecht, Jordan Berlin, Benjamin Allen, Ivana Bozic, Johannes G Reiter, Martin A Nowak,[...]. Nature 2012
4
Detection and localization of surgically resectable cancers with a multi-analyte blood test.
Joshua D Cohen, Lu Li, Yuxuan Wang, Christopher Thoburn, Bahman Afsari, Ludmila Danilova, Christopher Douville, Ammar A Javed, Fay Wong, Austin Mattox,[...]. Science 2018
Joshua D Cohen, Lu Li, Yuxuan Wang, Christopher Thoburn, Bahman Afsari, Ludmila Danilova, Christopher Douville, Ammar A Javed, Fay Wong, Austin Mattox,[...]. Science 2018
4
Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis.
Nicola Aceto, Aditya Bardia, David T Miyamoto, Maria C Donaldson, Ben S Wittner, Joel A Spencer, Min Yu, Adam Pely, Amanda Engstrom, Huili Zhu,[...]. Cell 2014
Nicola Aceto, Aditya Bardia, David T Miyamoto, Maria C Donaldson, Ben S Wittner, Joel A Spencer, Min Yu, Adam Pely, Amanda Engstrom, Huili Zhu,[...]. Cell 2014
4
The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers.
Pedram Razavi, Matthew T Chang, Guotai Xu, Chaitanya Bandlamudi, Dara S Ross, Neil Vasan, Yanyan Cai, Craig M Bielski, Mark T A Donoghue, Philip Jonsson,[...]. Cancer Cell 2018
Pedram Razavi, Matthew T Chang, Guotai Xu, Chaitanya Bandlamudi, Dara S Ross, Neil Vasan, Yanyan Cai, Craig M Bielski, Mark T A Donoghue, Philip Jonsson,[...]. Cancer Cell 2018
4
Circulating tumor cells, disease progression, and survival in metastatic breast cancer.
Massimo Cristofanilli, G Thomas Budd, Matthew J Ellis, Alison Stopeck, Jeri Matera, M Craig Miller, James M Reuben, Gerald V Doyle, W Jeffrey Allard, Leon W M M Terstappen,[...]. N Engl J Med 2004
Massimo Cristofanilli, G Thomas Budd, Matthew J Ellis, Alison Stopeck, Jeri Matera, M Craig Miller, James M Reuben, Gerald V Doyle, W Jeffrey Allard, Leon W M M Terstappen,[...]. N Engl J Med 2004
4
Genome remodelling in a basal-like breast cancer metastasis and xenograft.
Li Ding, Matthew J Ellis, Shunqiang Li, David E Larson, Ken Chen, John W Wallis, Christopher C Harris, Michael D McLellan, Robert S Fulton, Lucinda L Fulton,[...]. Nature 2010
Li Ding, Matthew J Ellis, Shunqiang Li, David E Larson, Ken Chen, John W Wallis, Christopher C Harris, Michael D McLellan, Robert S Fulton, Lucinda L Fulton,[...]. Nature 2010
4
Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer.
Andrew McPherson, Andrew Roth, Emma Laks, Tehmina Masud, Ali Bashashati, Allen W Zhang, Gavin Ha, Justina Biele, Damian Yap, Adrian Wan,[...]. Nat Genet 2016
Andrew McPherson, Andrew Roth, Emma Laks, Tehmina Masud, Ali Bashashati, Allen W Zhang, Gavin Ha, Justina Biele, Damian Yap, Adrian Wan,[...]. Nat Genet 2016
4
Tumor evolution: Linear, branching, neutral or punctuated?
Alexander Davis, Ruli Gao, Nicholas Navin. Biochim Biophys Acta Rev Cancer 2017
Alexander Davis, Ruli Gao, Nicholas Navin. Biochim Biophys Acta Rev Cancer 2017
4
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.