Yasmin M Ramdzan, Saskia Polling, Cheryl P Z Chia, Ivan H W Ng, Angelique R Ormsby, Nathan P Croft, Anthony W Purcell, Marie A Bogoyevitch, Dominic C H Ng, Paul A Gleeson, Danny M Hatters. Nat Methods 2012
Times Cited: 76
Times Cited: 76
Times Cited
Times Co-cited
Similarity
Misfolded proteins partition between two distinct quality control compartments.
Daniel Kaganovich, Ron Kopito, Judith Frydman. Nature 2008
Daniel Kaganovich, Ron Kopito, Judith Frydman. Nature 2008
26
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
23
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
18
Firefly luciferase mutants as sensors of proteome stress.
Rajat Gupta, Prasad Kasturi, Andreas Bracher, Christian Loew, Min Zheng, Adriana Villella, Dan Garza, F Ulrich Hartl, Swasti Raychaudhuri. Nat Methods 2011
Rajat Gupta, Prasad Kasturi, Andreas Bracher, Christian Loew, Min Zheng, Adriana Villella, Dan Garza, F Ulrich Hartl, Swasti Raychaudhuri. Nat Methods 2011
18
Tracking mutant huntingtin aggregation kinetics in cells reveals three major populations that include an invariant oligomer pool.
Maya A Olshina, Lauren M Angley, Yasmin M Ramdzan, Jinwei Tang, Michael F Bailey, Andrew F Hill, Danny M Hatters. J Biol Chem 2010
Maya A Olshina, Lauren M Angley, Yasmin M Ramdzan, Jinwei Tang, Michael F Bailey, Andrew F Hill, Danny M Hatters. J Biol Chem 2010
15
Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology.
E Scherzinger, A Sittler, K Schweiger, V Heiser, R Lurz, R Hasenbank, G P Bates, H Lehrach, E E Wanker. Proc Natl Acad Sci U S A 1999
E Scherzinger, A Sittler, K Schweiger, V Heiser, R Lurz, R Hasenbank, G P Bates, H Lehrach, E E Wanker. Proc Natl Acad Sci U S A 1999
15
Aggresomes: a cellular response to misfolded proteins.
J A Johnston, C L Ward, R R Kopito. J Cell Biol 1998
J A Johnston, C L Ward, R R Kopito. J Cell Biol 1998
14
Progressive disruption of cellular protein folding in models of polyglutamine diseases.
Tali Gidalevitz, Anat Ben-Zvi, Kim H Ho, Heather R Brignull, Richard I Morimoto. Science 2006
Tali Gidalevitz, Anat Ben-Zvi, Kim H Ho, Heather R Brignull, Richard I Morimoto. Science 2006
13
Adapting proteostasis for disease intervention.
William E Balch, Richard I Morimoto, Andrew Dillin, Jeffery W Kelly. Science 2008
William E Balch, Richard I Morimoto, Andrew Dillin, Jeffery W Kelly. Science 2008
13
Conformation sensors that distinguish monomeric proteins from oligomers in live cells.
Yasmin M Ramdzan, Rebecca M Nisbet, Jason Miller, Steven Finkbeiner, Andrew F Hill, Danny M Hatters. Chem Biol 2010
Yasmin M Ramdzan, Rebecca M Nisbet, Jason Miller, Steven Finkbeiner, Andrew F Hill, Danny M Hatters. Chem Biol 2010
32
Protein misfolding, functional amyloid, and human disease.
Fabrizio Chiti, Christopher M Dobson. Annu Rev Biochem 2006
Fabrizio Chiti, Christopher M Dobson. Annu Rev Biochem 2006
11
11
Huntingtin and mutant SOD1 form aggregate structures with distinct molecular properties in human cells.
Gen Matsumoto, Soojin Kim, Richard I Morimoto. J Biol Chem 2006
Gen Matsumoto, Soojin Kim, Richard I Morimoto. J Biol Chem 2006
10
Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo.
E Scherzinger, R Lurz, M Turmaine, L Mangiarini, B Hollenbach, R Hasenbank, G P Bates, S W Davies, H Lehrach, E E Wanker. Cell 1997
E Scherzinger, R Lurz, M Turmaine, L Mangiarini, B Hollenbach, R Hasenbank, G P Bates, S W Davies, H Lehrach, E E Wanker. Cell 1997
10
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
10
Monitoring protein stability and aggregation in vivo by real-time fluorescent labeling.
Zoya Ignatova, Lila M Gierasch. Proc Natl Acad Sci U S A 2004
Zoya Ignatova, Lila M Gierasch. Proc Natl Acad Sci U S A 2004
10
Biological and chemical approaches to diseases of proteostasis deficiency.
Evan T Powers, Richard I Morimoto, Andrew Dillin, Jeffery W Kelly, William E Balch. Annu Rev Biochem 2009
Evan T Powers, Richard I Morimoto, Andrew Dillin, Jeffery W Kelly, William E Balch. Annu Rev Biochem 2009
10
A biosensor-based framework to measure latent proteostasis capacity.
Rebecca J Wood, Angelique R Ormsby, Mona Radwan, Dezerae Cox, Abhishek Sharma, Tobias Vöpel, Simon Ebbinghaus, Mikael Oliveberg, Gavin E Reid, Alex Dickson,[...]. Nat Commun 2018
Rebecca J Wood, Angelique R Ormsby, Mona Radwan, Dezerae Cox, Abhishek Sharma, Tobias Vöpel, Simon Ebbinghaus, Mikael Oliveberg, Gavin E Reid, Alex Dickson,[...]. Nat Commun 2018
38
Detection of polyglutamine protein oligomers in cells by fluorescence correlation spectroscopy.
Yasuo Takahashi, Yuma Okamoto, H Akiko Popiel, Nobuhiro Fujikake, Tatsushi Toda, Masataka Kinjo, Yoshitaka Nagai. J Biol Chem 2007
Yasuo Takahashi, Yuma Okamoto, H Akiko Popiel, Nobuhiro Fujikake, Tatsushi Toda, Masataka Kinjo, Yoshitaka Nagai. J Biol Chem 2007
9
Proteostasis of polyglutamine varies among neurons and predicts neurodegeneration.
Andrey S Tsvetkov, Montserrat Arrasate, Sami Barmada, D Michael Ando, Punita Sharma, Benjamin A Shaby, Steven Finkbeiner. Nat Chem Biol 2013
Andrey S Tsvetkov, Montserrat Arrasate, Sami Barmada, D Michael Ando, Punita Sharma, Benjamin A Shaby, Steven Finkbeiner. Nat Chem Biol 2013
9
A platform to view huntingtin exon 1 aggregation flux in the cell reveals divergent influences from chaperones hsp40 and hsp70.
Angelique R Ormsby, Yasmin M Ramdzan, Yee-Foong Mok, Kristijan D Jovanoski, Danny M Hatters. J Biol Chem 2013
Angelique R Ormsby, Yasmin M Ramdzan, Yee-Foong Mok, Kristijan D Jovanoski, Danny M Hatters. J Biol Chem 2013
35
Quantitative and spatio-temporal features of protein aggregation in Escherichia coli and consequences on protein quality control and cellular ageing.
Juliane Winkler, Anja Seybert, Lars König, Sabine Pruggnaller, Uta Haselmann, Victor Sourjik, Matthias Weiss, Achilleas S Frangakis, Axel Mogk, Bernd Bukau. EMBO J 2010
Juliane Winkler, Anja Seybert, Lars König, Sabine Pruggnaller, Uta Haselmann, Victor Sourjik, Matthias Weiss, Achilleas S Frangakis, Axel Mogk, Bernd Bukau. EMBO J 2010
9
Conformational analysis of misfolded protein aggregation by FRET and live-cell imaging techniques.
Akira Kitamura, Kazuhiro Nagata, Masataka Kinjo. Int J Mol Sci 2015
Akira Kitamura, Kazuhiro Nagata, Masataka Kinjo. Int J Mol Sci 2015
41
Rapid flow cytometric measurement of protein inclusions and nuclear trafficking.
D R Whiten, R San Gil, L McAlary, J J Yerbury, H Ecroyd, M R Wilson. Sci Rep 2016
D R Whiten, R San Gil, L McAlary, J J Yerbury, H Ecroyd, M R Wilson. Sci Rep 2016
30
Soluble polyglutamine oligomers formed prior to inclusion body formation are cytotoxic.
Toshiaki Takahashi, Shinya Kikuchi, Shinichi Katada, Yoshitaka Nagai, Masatoyo Nishizawa, Osamu Onodera. Hum Mol Genet 2008
Toshiaki Takahashi, Shinya Kikuchi, Shinichi Katada, Yoshitaka Nagai, Masatoyo Nishizawa, Osamu Onodera. Hum Mol Genet 2008
7
Cellular strategies for controlling protein aggregation.
Jens Tyedmers, Axel Mogk, Bernd Bukau. Nat Rev Mol Cell Biol 2010
Jens Tyedmers, Axel Mogk, Bernd Bukau. Nat Rev Mol Cell Biol 2010
7
Protein aggregation and neurodegenerative disease.
Christopher A Ross, Michelle A Poirier. Nat Med 2004
Christopher A Ross, Michelle A Poirier. Nat Med 2004
7
Putting huntingtin "aggregation" in view with windows into the cellular milieu.
Danny M Hatters. Curr Top Med Chem 2012
Danny M Hatters. Curr Top Med Chem 2012
50
Molecular chaperones in protein folding and proteostasis.
F Ulrich Hartl, Andreas Bracher, Manajit Hayer-Hartl. Nature 2011
F Ulrich Hartl, Andreas Bracher, Manajit Hayer-Hartl. Nature 2011
7
PolyQ proteins interfere with nuclear degradation of cytosolic proteins by sequestering the Sis1p chaperone.
Sae-Hun Park, Yury Kukushkin, Rajat Gupta, Taotao Chen, Ayano Konagai, Mark S Hipp, Manajit Hayer-Hartl, F Ulrich Hartl. Cell 2013
Sae-Hun Park, Yury Kukushkin, Rajat Gupta, Taotao Chen, Ayano Konagai, Mark S Hipp, Manajit Hayer-Hartl, F Ulrich Hartl. Cell 2013
7
Misfolded polyglutamine, polyalanine, and superoxide dismutase 1 aggregate via distinct pathways in the cell.
Saskia Polling, Yee-Foong Mok, Yasmin M Ramdzan, Bradley J Turner, Justin J Yerbury, Andrew F Hill, Danny M Hatters. J Biol Chem 2014
Saskia Polling, Yee-Foong Mok, Yasmin M Ramdzan, Bradley J Turner, Justin J Yerbury, Andrew F Hill, Danny M Hatters. J Biol Chem 2014
22
Proteostasis impairment in protein-misfolding and -aggregation diseases.
Mark S Hipp, Sae-Hun Park, F Ulrich Hartl. Trends Cell Biol 2014
Mark S Hipp, Sae-Hun Park, F Ulrich Hartl. Trends Cell Biol 2014
7
The amyloid state and its association with protein misfolding diseases.
Tuomas P J Knowles, Michele Vendruscolo, Christopher M Dobson. Nat Rev Mol Cell Biol 2014
Tuomas P J Knowles, Michele Vendruscolo, Christopher M Dobson. Nat Rev Mol Cell Biol 2014
7
Fluorescence Turn-On Folding Sensor To Monitor Proteome Stress in Live Cells.
Yu Liu, Xin Zhang, Wentao Chen, Yun Lei Tan, Jeffery W Kelly. J Am Chem Soc 2015
Yu Liu, Xin Zhang, Wentao Chen, Yun Lei Tan, Jeffery W Kelly. J Am Chem Soc 2015
24
HaloTag: a novel protein labeling technology for cell imaging and protein analysis.
Georgyi V Los, Lance P Encell, Mark G McDougall, Danette D Hartzell, Natasha Karassina, Chad Zimprich, Monika G Wood, Randy Learish, Rachel Friedman Ohana, Marjeta Urh,[...]. ACS Chem Biol 2008
Georgyi V Los, Lance P Encell, Mark G McDougall, Danette D Hartzell, Natasha Karassina, Chad Zimprich, Monika G Wood, Randy Learish, Rachel Friedman Ohana, Marjeta Urh,[...]. ACS Chem Biol 2008
7
AgHalo: A Facile Fluorogenic Sensor to Detect Drug-Induced Proteome Stress.
Yu Liu, Matthew Fares, Noah P Dunham, Zi Gao, Kun Miao, Xueyuan Jiang, Samuel S Bollinger, Amie K Boal, Xin Zhang. Angew Chem Int Ed Engl 2017
Yu Liu, Matthew Fares, Noah P Dunham, Zi Gao, Kun Miao, Xueyuan Jiang, Samuel S Bollinger, Amie K Boal, Xin Zhang. Angew Chem Int Ed Engl 2017
13
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases.
Monica Bucciantini, Elisa Giannoni, Fabrizio Chiti, Fabiana Baroni, Lucia Formigli, Jesús Zurdo, Niccolò Taddei, Giampietro Ramponi, Christopher M Dobson, Massimo Stefani. Nature 2002
Monica Bucciantini, Elisa Giannoni, Fabrizio Chiti, Fabiana Baroni, Lucia Formigli, Jesús Zurdo, Niccolò Taddei, Giampietro Ramponi, Christopher M Dobson, Massimo Stefani. Nature 2002
6
6
Doublet discrimination in DNA cell-cycle analysis.
R P Wersto, F J Chrest, J F Leary, C Morris, M A Stetler-Stevenson, E Gabrielson. Cytometry 2001
R P Wersto, F J Chrest, J F Leary, C Morris, M A Stetler-Stevenson, E Gabrielson. Cytometry 2001
6
Compartmentalization of superoxide dismutase 1 (SOD1G93A) aggregates determines their toxicity.
Sarah J Weisberg, Roman Lyakhovetsky, Ayelet-chen Werdiger, Aaron D Gitler, Yoav Soen, Daniel Kaganovich. Proc Natl Acad Sci U S A 2012
Sarah J Weisberg, Roman Lyakhovetsky, Ayelet-chen Werdiger, Aaron D Gitler, Yoav Soen, Daniel Kaganovich. Proc Natl Acad Sci U S A 2012
6
Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1.
L I Bruijn, M K Houseweart, S Kato, K L Anderson, S D Anderson, E Ohama, A G Reaume, R W Scott, D W Cleveland. Science 1998
L I Bruijn, M K Houseweart, S Kato, K L Anderson, S D Anderson, E Ohama, A G Reaume, R W Scott, D W Cleveland. Science 1998
6
Opinion: What is the role of protein aggregation in neurodegeneration?
Christopher A Ross, Michelle A Poirier. Nat Rev Mol Cell Biol 2005
Christopher A Ross, Michelle A Poirier. Nat Rev Mol Cell Biol 2005
6
Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions.
Heidi Olzscha, Sonya M Schermann, Andreas C Woerner, Stefan Pinkert, Michael H Hecht, Gian G Tartaglia, Michele Vendruscolo, Manajit Hayer-Hartl, F Ulrich Hartl, R Martin Vabulas. Cell 2011
Heidi Olzscha, Sonya M Schermann, Andreas C Woerner, Stefan Pinkert, Michael H Hecht, Gian G Tartaglia, Michele Vendruscolo, Manajit Hayer-Hartl, F Ulrich Hartl, R Martin Vabulas. Cell 2011
6
The Cation-π Interaction Enables a Halo-Tag Fluorogenic Probe for Fast No-Wash Live Cell Imaging and Gel-Free Protein Quantification.
Yu Liu, Kun Miao, Noah P Dunham, Hongbin Liu, Matthew Fares, Amie K Boal, Xiaosong Li, Xin Zhang. Biochemistry 2017
Yu Liu, Kun Miao, Noah P Dunham, Hongbin Liu, Matthew Fares, Amie K Boal, Xiaosong Li, Xin Zhang. Biochemistry 2017
14
Self-Assembling NanoLuc Luciferase Fragments as Probes for Protein Aggregation in Living Cells.
Jia Zhao, Travis J Nelson, Quyen Vu, Tiffany Truong, Cliff I Stains. ACS Chem Biol 2016
Jia Zhao, Travis J Nelson, Quyen Vu, Tiffany Truong, Cliff I Stains. ACS Chem Biol 2016
16
Rapid protein-folding assay using green fluorescent protein.
G S Waldo, B M Standish, J Berendzen, T C Terwilliger. Nat Biotechnol 1999
G S Waldo, B M Standish, J Berendzen, T C Terwilliger. Nat Biotechnol 1999
6
Monitoring protein misfolding by site-specific labeling of proteins in vivo.
Tzung-yang Hsieh, Nadinath B Nillegoda, Jens Tyedmers, Bernd Bukau, Axel Mogk, Günter Kramer. PLoS One 2014
Tzung-yang Hsieh, Nadinath B Nillegoda, Jens Tyedmers, Bernd Bukau, Axel Mogk, Günter Kramer. PLoS One 2014
33
Highly sensitive amyloid detection enabled by thioflavin T dimers.
Luoheng Qin, Julian Vastl, Jianmin Gao. Mol Biosyst 2010
Luoheng Qin, Julian Vastl, Jianmin Gao. Mol Biosyst 2010
17
Huntingtin Inclusions Trigger Cellular Quiescence, Deactivate Apoptosis, and Lead to Delayed Necrosis.
Yasmin M Ramdzan, Mikhail M Trubetskov, Angelique R Ormsby, Estella A Newcombe, Xiaojing Sui, Mark J Tobin, Marie N Bongiovanni, Sally L Gras, Grant Dewson, Jason M L Miller,[...]. Cell Rep 2017
Yasmin M Ramdzan, Mikhail M Trubetskov, Angelique R Ormsby, Estella A Newcombe, Xiaojing Sui, Mark J Tobin, Marie N Bongiovanni, Sally L Gras, Grant Dewson, Jason M L Miller,[...]. Cell Rep 2017
7
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade.
Fabrizio Chiti, Christopher M Dobson. Annu Rev Biochem 2017
Fabrizio Chiti, Christopher M Dobson. Annu Rev Biochem 2017
6
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