Ori Bar-Nur, Inbal Caspi, Nissim Benvenisty. J Mol Cell Biol 2012
Times Cited: 58
Times Cited: 58
Times Cited
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Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells.
Achia Urbach, Ori Bar-Nur, George Q Daley, Nissim Benvenisty. Cell Stem Cell 2010
Achia Urbach, Ori Bar-Nur, George Q Daley, Nissim Benvenisty. Cell Stem Cell 2010
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Epigenetic characterization of the FMR1 gene and aberrant neurodevelopment in human induced pluripotent stem cell models of fragile X syndrome.
Steven D Sheridan, Kraig M Theriault, Surya A Reis, Fen Zhou, Jon M Madison, Laurence Daheron, Jeanne F Loring, Stephen J Haggarty. PLoS One 2011
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Developmental study of fragile X syndrome using human embryonic stem cells derived from preimplantation genetically diagnosed embryos.
Rachel Eiges, Achia Urbach, Mira Malcov, Tsvia Frumkin, Tamar Schwartz, Ami Amit, Yuval Yaron, Amir Eden, Ofra Yanuka, Nissim Benvenisty,[...]. Cell Stem Cell 2007
Rachel Eiges, Achia Urbach, Mira Malcov, Tsvia Frumkin, Tamar Schwartz, Ami Amit, Yuval Yaron, Amir Eden, Ofra Yanuka, Nissim Benvenisty,[...]. Cell Stem Cell 2007
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Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome.
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Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki, Megumi Narita, Tomoko Ichisaka, Kiichiro Tomoda, Shinya Yamanaka. Cell 2007
Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki, Megumi Narita, Tomoko Ichisaka, Kiichiro Tomoda, Shinya Yamanaka. Cell 2007
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Normal phenotype in two brothers with a full FMR1 mutation.
H J Smeets, A P Smits, C E Verheij, J P Theelen, R Willemsen, I van de Burgt, A T Hoogeveen, J C Oosterwijk, B A Oostra. Hum Mol Genet 1995
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A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells.
Maria C N Marchetto, Cassiano Carromeu, Allan Acab, Diana Yu, Gene W Yeo, Yangling Mu, Gong Chen, Fred H Gage, Alysson R Muotri. Cell 2010
Maria C N Marchetto, Cassiano Carromeu, Allan Acab, Diana Yu, Gene W Yeo, Yangling Mu, Gong Chen, Fred H Gage, Alysson R Muotri. Cell 2010
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Reversion of FMR1 Methylation and Silencing by Editing the Triplet Repeats in Fragile X iPSC-Derived Neurons.
Chul-Yong Park, Tomer Halevy, Dongjin R Lee, Jin Jea Sung, Jae Souk Lee, Ofra Yanuka, Nissim Benvenisty, Dong-Wook Kim. Cell Rep 2015
Chul-Yong Park, Tomer Halevy, Dongjin R Lee, Jin Jea Sung, Jae Souk Lee, Ofra Yanuka, Nissim Benvenisty, Dong-Wook Kim. Cell Rep 2015
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In vitro reactivation of the FMR1 gene involved in fragile X syndrome.
P Chiurazzi, M G Pomponi, R Willemsen, B A Oostra, G Neri. Hum Mol Genet 1998
P Chiurazzi, M G Pomponi, R Willemsen, B A Oostra, G Neri. Hum Mol Genet 1998
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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.
Kazutoshi Takahashi, Shinya Yamanaka. Cell 2006
Kazutoshi Takahashi, Shinya Yamanaka. Cell 2006
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Promoter-bound trinucleotide repeat mRNA drives epigenetic silencing in fragile X syndrome.
Dilek Colak, Nikica Zaninovic, Michael S Cohen, Zev Rosenwaks, Wang-Yong Yang, Jeannine Gerhardt, Matthew D Disney, Samie R Jaffrey. Science 2014
Dilek Colak, Nikica Zaninovic, Michael S Cohen, Zev Rosenwaks, Wang-Yong Yang, Jeannine Gerhardt, Matthew D Disney, Samie R Jaffrey. Science 2014
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Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells.
B Coffee, F Zhang, S T Warren, D Reines. Nat Genet 1999
B Coffee, F Zhang, S T Warren, D Reines. Nat Genet 1999
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Epigenetic characterization of the FMR1 promoter in induced pluripotent stem cells from human fibroblasts carrying an unmethylated full mutation.
Celine E F de Esch, Mehrnaz Ghazvini, Friedemann Loos, Nune Schelling-Kazaryan, W Widagdo, Shashini T Munshi, Erik van der Wal, Hannie Douben, Nilhan Gunhanlar, Steven A Kushner,[...]. Stem Cell Reports 2014
Celine E F de Esch, Mehrnaz Ghazvini, Friedemann Loos, Nune Schelling-Kazaryan, W Widagdo, Shashini T Munshi, Erik van der Wal, Hannie Douben, Nilhan Gunhanlar, Steven A Kushner,[...]. Stem Cell Reports 2014
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Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome.
Sergiu P Paşca, Thomas Portmann, Irina Voineagu, Masayuki Yazawa, Aleksandr Shcheglovitov, Anca M Paşca, Branden Cord, Theo D Palmer, Sachiko Chikahisa, Seiji Nishino,[...]. Nat Med 2011
Sergiu P Paşca, Thomas Portmann, Irina Voineagu, Masayuki Yazawa, Aleksandr Shcheglovitov, Anca M Paşca, Branden Cord, Theo D Palmer, Sachiko Chikahisa, Seiji Nishino,[...]. Nat Med 2011
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Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling.
Stuart M Chambers, Christopher A Fasano, Eirini P Papapetrou, Mark Tomishima, Michel Sadelain, Lorenz Studer. Nat Biotechnol 2009
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Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation.
Aaron Y L Cheung, Lindsay M Horvath, Daria Grafodatskaya, Peter Pasceri, Rosanna Weksberg, Akitsu Hotta, Laura Carrel, James Ellis. Hum Mol Genet 2011
Aaron Y L Cheung, Lindsay M Horvath, Daria Grafodatskaya, Peter Pasceri, Rosanna Weksberg, Akitsu Hotta, Laura Carrel, James Ellis. Hum Mol Genet 2011
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Cerebral organoids model human brain development and microcephaly.
Madeline A Lancaster, Magdalena Renner, Carol-Anne Martin, Daniel Wenzel, Louise S Bicknell, Matthew E Hurles, Tessa Homfray, Josef M Penninger, Andrew P Jackson, Juergen A Knoblich. Nature 2013
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Molecular mechanisms regulating the defects in fragile X syndrome neurons derived from human pluripotent stem cells.
Tomer Halevy, Christian Czech, Nissim Benvenisty. Stem Cell Reports 2015
Tomer Halevy, Christian Czech, Nissim Benvenisty. Stem Cell Reports 2015
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iPSC-derived forebrain neurons from FXS individuals show defects in initial neurite outgrowth.
Matthew E Doers, Michael T Musser, Robert Nichol, Erich R Berndt, Mei Baker, Timothy M Gomez, Su-Chun Zhang, Leonard Abbeduto, Anita Bhattacharyya. Stem Cells Dev 2014
Matthew E Doers, Michael T Musser, Robert Nichol, Erich R Berndt, Mei Baker, Timothy M Gomez, Su-Chun Zhang, Leonard Abbeduto, Anita Bhattacharyya. Stem Cells Dev 2014
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High-Throughput Screening Using iPSC-Derived Neuronal Progenitors to Identify Compounds Counteracting Epigenetic Gene Silencing in Fragile X Syndrome.
Markus Kaufmann, Ansgar Schuffenhauer, Isabelle Fruh, Jessica Klein, Anke Thiemeyer, Pierre Rigo, Baltazar Gomez-Mancilla, Valerie Heidinger-Millot, Tewis Bouwmeester, Ulrich Schopfer,[...]. J Biomol Screen 2015
Markus Kaufmann, Ansgar Schuffenhauer, Isabelle Fruh, Jessica Klein, Anke Thiemeyer, Pierre Rigo, Baltazar Gomez-Mancilla, Valerie Heidinger-Millot, Tewis Bouwmeester, Ulrich Schopfer,[...]. J Biomol Screen 2015
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Timing of the absence of FMR1 expression in full mutation chorionic villi.
Rob Willemsen, Carola J M Bontekoe, Lies-Anne Severijnen, Ben A Oostra. Hum Genet 2002
Rob Willemsen, Carola J M Bontekoe, Lies-Anne Severijnen, Ben A Oostra. Hum Genet 2002
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SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients.
Aleksandr Shcheglovitov, Olesya Shcheglovitova, Masayuki Yazawa, Thomas Portmann, Rui Shu, Vittorio Sebastiano, Anna Krawisz, Wendy Froehlich, Jonathan A Bernstein, Joachim F Hallmayer,[...]. Nature 2013
Aleksandr Shcheglovitov, Olesya Shcheglovitova, Masayuki Yazawa, Thomas Portmann, Rui Shu, Vittorio Sebastiano, Anna Krawisz, Wendy Froehlich, Jonathan A Bernstein, Joachim F Hallmayer,[...]. Nature 2013
22
FMR1 epigenetic silencing commonly occurs in undifferentiated fragile X-affected embryonic stem cells.
Michal Avitzour, Hagar Mor-Shaked, Shira Yanovsky-Dagan, Shira Aharoni, Gheona Altarescu, Paul Renbaum, Talia Eldar-Geva, Oshrat Schonberger, Ephrat Levy-Lahad, Silvina Epsztejn-Litman,[...]. Stem Cell Reports 2014
Michal Avitzour, Hagar Mor-Shaked, Shira Yanovsky-Dagan, Shira Aharoni, Gheona Altarescu, Paul Renbaum, Talia Eldar-Geva, Oshrat Schonberger, Ephrat Levy-Lahad, Silvina Epsztejn-Litman,[...]. Stem Cell Reports 2014
28
High-Throughput Screening to Identify Compounds That Increase Fragile X Mental Retardation Protein Expression in Neural Stem Cells Differentiated From Fragile X Syndrome Patient-Derived Induced Pluripotent Stem Cells.
Daman Kumari, Manju Swaroop, Noel Southall, Wenwei Huang, Wei Zheng, Karen Usdin. Stem Cells Transl Med 2015
Daman Kumari, Manju Swaroop, Noel Southall, Wenwei Huang, Wei Zheng, Karen Usdin. Stem Cells Transl Med 2015
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Neuronal maturation defect in induced pluripotent stem cells from patients with Rett syndrome.
Kun-Yong Kim, Eriona Hysolli, In-Hyun Park. Proc Natl Acad Sci U S A 2011
Kun-Yong Kim, Eriona Hysolli, In-Hyun Park. Proc Natl Acad Sci U S A 2011
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Synergistic effect of histone hyperacetylation and DNA demethylation in the reactivation of the FMR1 gene.
P Chiurazzi, M G Pomponi, R Pietrobono, C E Bakker, G Neri, B A Oostra. Hum Mol Genet 1999
P Chiurazzi, M G Pomponi, R Pietrobono, C E Bakker, G Neri, B A Oostra. Hum Mol Genet 1999
20
Molecular dissection of the events leading to inactivation of the FMR1 gene.
Roberta Pietrobono, Elisabetta Tabolacci, Francesca Zalfa, Ilaria Zito, Alessandra Terracciano, Umberto Moscato, Claudia Bagni, Ben Oostra, Pietro Chiurazzi, Giovanni Neri. Hum Mol Genet 2005
Roberta Pietrobono, Elisabetta Tabolacci, Francesca Zalfa, Ilaria Zito, Alessandra Terracciano, Umberto Moscato, Claudia Bagni, Ben Oostra, Pietro Chiurazzi, Giovanni Neri. Hum Mol Genet 2005
20
Signaling defects in iPSC-derived fragile X premutation neurons.
Jing Liu, Katarzyna A Koscielska, Zhengyu Cao, Susan Hulsizer, Natalie Grace, Gaela Mitchell, Catherine Nacey, Jackline Githinji, Jeannine McGee, Dolores Garcia-Arocena,[...]. Hum Mol Genet 2012
Jing Liu, Katarzyna A Koscielska, Zhengyu Cao, Susan Hulsizer, Natalie Grace, Gaela Mitchell, Catherine Nacey, Jackline Githinji, Jeannine McGee, Dolores Garcia-Arocena,[...]. Hum Mol Genet 2012
20
Neural differentiation of Fragile X human Embryonic Stem Cells reveals abnormal patterns of development despite successful neurogenesis.
Michael Telias, Menahem Segal, Dalit Ben-Yosef. Dev Biol 2013
Michael Telias, Menahem Segal, Dalit Ben-Yosef. Dev Biol 2013
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Isogenic pairs of wild type and mutant induced pluripotent stem cell (iPSC) lines from Rett syndrome patients as in vitro disease model.
Gene Ananiev, Emily Cunningham Williams, Hongda Li, Qiang Chang. PLoS One 2011
Gene Ananiev, Emily Cunningham Williams, Hongda Li, Qiang Chang. PLoS One 2011
18
Quantitative analysis of DNA demethylation and transcriptional reactivation of the FMR1 gene in fragile X cells treated with 5-azadeoxycytidine.
Roberta Pietrobono, Maria Grazia Pomponi, Elisabetta Tabolacci, Ben Oostra, Pietro Chiurazzi, Giovanni Neri. Nucleic Acids Res 2002
Roberta Pietrobono, Maria Grazia Pomponi, Elisabetta Tabolacci, Ben Oostra, Pietro Chiurazzi, Giovanni Neri. Nucleic Acids Res 2002
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Histone modifications depict an aberrantly heterochromatinized FMR1 gene in fragile x syndrome.
Bradford Coffee, Fuping Zhang, Stephanie Ceman, Stephen T Warren, Daniel Reines. Am J Hum Genet 2002
Bradford Coffee, Fuping Zhang, Stephanie Ceman, Stephen T Warren, Daniel Reines. Am J Hum Genet 2002
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Induced pluripotent stem cell models of the genomic imprinting disorders Angelman and Prader-Willi syndromes.
Stormy J Chamberlain, Pin-Fang Chen, Khong Y Ng, Fany Bourgois-Rocha, Fouad Lemtiri-Chlieh, Eric S Levine, Marc Lalande. Proc Natl Acad Sci U S A 2010
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18
Human embryonic stem cell lines with genetic disorders.
Y Verlinsky, N Strelchenko, V Kukharenko, S Rechitsky, O Verlinsky, V Galat, A Kuliev. Reprod Biomed Online 2005
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Modelling schizophrenia using human induced pluripotent stem cells.
Kristen J Brennand, Anthony Simone, Jessica Jou, Chelsea Gelboin-Burkhart, Ngoc Tran, Sarah Sangar, Yan Li, Yangling Mu, Gong Chen, Diana Yu,[...]. Nature 2011
Kristen J Brennand, Anthony Simone, Jessica Jou, Chelsea Gelboin-Burkhart, Ngoc Tran, Sarah Sangar, Yan Li, Yangling Mu, Gong Chen, Diana Yu,[...]. Nature 2011
17
Epigenetic analysis reveals a euchromatic configuration in the FMR1 unmethylated full mutations.
Elisabetta Tabolacci, Umberto Moscato, Francesca Zalfa, Claudia Bagni, Pietro Chiurazzi, Giovanni Neri. Eur J Hum Genet 2008
Elisabetta Tabolacci, Umberto Moscato, Francesca Zalfa, Claudia Bagni, Pietro Chiurazzi, Giovanni Neri. Eur J Hum Genet 2008
17
Differential epigenetic modifications in the FMR1 gene of the fragile X syndrome after reactivating pharmacological treatments.
Elisabetta Tabolacci, Roberta Pietrobono, Umberto Moscato, Ben A Oostra, Pietro Chiurazzi, Giovanni Neri. Eur J Hum Genet 2005
Elisabetta Tabolacci, Roberta Pietrobono, Umberto Moscato, Ben A Oostra, Pietro Chiurazzi, Giovanni Neri. Eur J Hum Genet 2005
17
Modest reactivation of the mutant FMR1 gene by valproic acid is accompanied by histone modifications but not DNA demethylation.
Elisabetta Tabolacci, Ivana De Pascalis, Maria Accadia, Alessandra Terracciano, Umberto Moscato, Pietro Chiurazzi, Giovanni Neri. Pharmacogenet Genomics 2008
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Genome-wide analysis validates aberrant methylation in fragile X syndrome is specific to the FMR1 locus.
Reid S Alisch, Tao Wang, Pankaj Chopra, Jeannie Visootsak, Karen N Conneely, Stephen T Warren. BMC Med Genet 2013
Reid S Alisch, Tao Wang, Pankaj Chopra, Jeannie Visootsak, Karen N Conneely, Stephen T Warren. BMC Med Genet 2013
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Timothy syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons.
Jocelyn F Krey, Sergiu P Paşca, Aleksandr Shcheglovitov, Masayuki Yazawa, Rachel Schwemberger, Randall Rasmusson, Ricardo E Dolmetsch. Nat Neurosci 2013
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Embryonic stem cell lines derived from human blastocysts.
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Establishment of Reporter Lines for Detecting Fragile X Mental Retardation (FMR1) Gene Reactivation in Human Neural Cells.
Meng Li, Huashan Zhao, Gene E Ananiev, Michael T Musser, Kathryn H Ness, Dianne L Maglaque, Krishanu Saha, Anita Bhattacharyya, Xinyu Zhao. Stem Cells 2017
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Modeling human cortical development in vitro using induced pluripotent stem cells.
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15
An antisense transcript spanning the CGG repeat region of FMR1 is upregulated in premutation carriers but silenced in full mutation individuals.
Paula D Ladd, Leslie E Smith, Natalia A Rabaia, James M Moore, Sara A Georges, R Scott Hansen, Randi J Hagerman, Flora Tassone, Stephen J Tapscott, Galina N Filippova. Hum Mol Genet 2007
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Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2.
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Correction of fragile X syndrome in mice.
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Incidence of fragile X syndrome by newborn screening for methylated FMR1 DNA.
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DNA methylation represses FMR-1 transcription in fragile X syndrome.
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The DNA replication program is altered at the FMR1 locus in fragile X embryonic stem cells.
Jeannine Gerhardt, Mark J Tomishima, Nikica Zaninovic, Dilek Colak, Zi Yan, Qiansheng Zhan, Zev Rosenwaks, Samie R Jaffrey, Carl L Schildkraut. Mol Cell 2014
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Absence of expression of the FMR-1 gene in fragile X syndrome.
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15
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.