Pedro M Quirós, Andrew J Ramsay, David Sala, Erika Fernández-Vizarra, Francisco Rodríguez, Juan R Peinado, Maria Soledad Fernández-García, José A Vega, José A Enríquez, Antonio Zorzano, Carlos López-Otín. EMBO J 2012
Times Cited: 172
Times Cited: 172
Times Cited
Times Co-cited
Similarity
The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission.
Ruchika Anand, Timothy Wai, Michael J Baker, Nikolay Kladt, Astrid C Schauss, Elena Rugarli, Thomas Langer. J Cell Biol 2014
Ruchika Anand, Timothy Wai, Michael J Baker, Nikolay Kladt, Astrid C Schauss, Elena Rugarli, Thomas Langer. J Cell Biol 2014
40
Stress-induced OMA1 activation and autocatalytic turnover regulate OPA1-dependent mitochondrial dynamics.
Michael J Baker, Philipp A Lampe, Diana Stojanovski, Anne Korwitz, Ruchika Anand, Takashi Tatsuta, Thomas Langer. EMBO J 2014
Michael J Baker, Philipp A Lampe, Diana Stojanovski, Anne Korwitz, Ruchika Anand, Takashi Tatsuta, Thomas Langer. EMBO J 2014
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Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1.
Sarah Ehses, Ines Raschke, Giuseppe Mancuso, Andrea Bernacchia, Stefan Geimer, Daniel Tondera, Jean-Claude Martinou, Benedikt Westermann, Elena I Rugarli, Thomas Langer. J Cell Biol 2009
Sarah Ehses, Ines Raschke, Giuseppe Mancuso, Andrea Bernacchia, Stefan Geimer, Daniel Tondera, Jean-Claude Martinou, Benedikt Westermann, Elena I Rugarli, Thomas Langer. J Cell Biol 2009
33
Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells.
Brian Head, Lorena Griparic, Mandana Amiri, Shilpa Gandre-Babbe, Alexander M van der Bliek. J Cell Biol 2009
Brian Head, Lorena Griparic, Mandana Amiri, Shilpa Gandre-Babbe, Alexander M van der Bliek. J Cell Biol 2009
31
OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L.
Zhiyin Song, Hsiuchen Chen, Maja Fiket, Christiane Alexander, David C Chan. J Cell Biol 2007
Zhiyin Song, Hsiuchen Chen, Maja Fiket, Christiane Alexander, David C Chan. J Cell Biol 2007
29
Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice.
Timothy Wai, Jaime García-Prieto, Michael J Baker, Carsten Merkwirth, Paule Benit, Pierre Rustin, Francisco Javier Rupérez, Coral Barbas, Borja Ibañez, Thomas Langer. Science 2015
Timothy Wai, Jaime García-Prieto, Michael J Baker, Carsten Merkwirth, Paule Benit, Pierre Rustin, Francisco Javier Rupérez, Coral Barbas, Borja Ibañez, Thomas Langer. Science 2015
28
OPA1 processing in cell death and disease - the long and short of it.
Thomas MacVicar, Thomas Langer. J Cell Sci 2016
Thomas MacVicar, Thomas Langer. J Cell Sci 2016
27
Membrane depolarization activates the mitochondrial protease OMA1 by stimulating self-cleavage.
Kuan Zhang, Huihui Li, Zhiyin Song. EMBO Rep 2014
Kuan Zhang, Huihui Li, Zhiyin Song. EMBO Rep 2014
25
Reciprocal Degradation of YME1L and OMA1 Adapts Mitochondrial Proteolytic Activity during Stress.
T Kelly Rainbolt, Justine Lebeau, Cristina Puchades, R Luke Wiseman. Cell Rep 2016
T Kelly Rainbolt, Justine Lebeau, Cristina Puchades, R Luke Wiseman. Cell Rep 2016
25
Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria.
Anne Korwitz, Carsten Merkwirth, Ricarda Richter-Dennerlein, Simon E Tröder, Hans-Georg Sprenger, Pedro M Quirós, Carlos López-Otín, Elena I Rugarli, Thomas Langer. J Cell Biol 2016
Anne Korwitz, Carsten Merkwirth, Ricarda Richter-Dennerlein, Simon E Tröder, Hans-Georg Sprenger, Pedro M Quirós, Carlos López-Otín, Elena I Rugarli, Thomas Langer. J Cell Biol 2016
25
Regulation of mitochondrial morphology through proteolytic cleavage of OPA1.
Naotada Ishihara, Yuu Fujita, Toshihiko Oka, Katsuyoshi Mihara. EMBO J 2006
Naotada Ishihara, Yuu Fujita, Toshihiko Oka, Katsuyoshi Mihara. EMBO J 2006
21
OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion.
Christian Frezza, Sara Cipolat, Olga Martins de Brito, Massimo Micaroni, Galina V Beznoussenko, Tomasz Rudka, Davide Bartoli, Roman S Polishuck, Nika N Danial, Bart De Strooper,[...]. Cell 2006
Christian Frezza, Sara Cipolat, Olga Martins de Brito, Massimo Micaroni, Galina V Beznoussenko, Tomasz Rudka, Davide Bartoli, Roman S Polishuck, Nika N Danial, Bart De Strooper,[...]. Cell 2006
20
Mitochondrial Dynamics and Metabolic Regulation.
Timothy Wai, Thomas Langer. Trends Endocrinol Metab 2016
Timothy Wai, Thomas Langer. Trends Endocrinol Metab 2016
20
Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis.
David Sebastián, María Isabel Hernández-Alvarez, Jessica Segalés, Eleonora Sorianello, Juan Pablo Muñoz, David Sala, Aurélie Waget, Marc Liesa, José C Paz, Peddinti Gopalacharyulu,[...]. Proc Natl Acad Sci U S A 2012
David Sebastián, María Isabel Hernández-Alvarez, Jessica Segalés, Eleonora Sorianello, Juan Pablo Muñoz, David Sala, Aurélie Waget, Marc Liesa, José C Paz, Peddinti Gopalacharyulu,[...]. Proc Natl Acad Sci U S A 2012
18
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy.
Gilad Twig, Alvaro Elorza, Anthony J A Molina, Hibo Mohamed, Jakob D Wikstrom, Gil Walzer, Linsey Stiles, Sarah E Haigh, Steve Katz, Guy Las,[...]. EMBO J 2008
Gilad Twig, Alvaro Elorza, Anthony J A Molina, Hibo Mohamed, Jakob D Wikstrom, Gil Walzer, Linsey Stiles, Sarah E Haigh, Steve Katz, Guy Las,[...]. EMBO J 2008
17
Mitochondrial cristae shape determines respiratory chain supercomplexes assembly and respiratory efficiency.
Sara Cogliati, Christian Frezza, Maria Eugenia Soriano, Tatiana Varanita, Ruben Quintana-Cabrera, Mauro Corrado, Sara Cipolat, Veronica Costa, Alberto Casarin, Ligia C Gomes,[...]. Cell 2013
Sara Cogliati, Christian Frezza, Maria Eugenia Soriano, Tatiana Varanita, Ruben Quintana-Cabrera, Mauro Corrado, Sara Cipolat, Veronica Costa, Alberto Casarin, Ligia C Gomes,[...]. Cell 2013
17
The OPA1-dependent mitochondrial cristae remodeling pathway controls atrophic, apoptotic, and ischemic tissue damage.
Tatiana Varanita, Maria Eugenia Soriano, Vanina Romanello, Tania Zaglia, Rubén Quintana-Cabrera, Martina Semenzato, Roberta Menabò, Veronica Costa, Gabriele Civiletto, Paola Pesce,[...]. Cell Metab 2015
Tatiana Varanita, Maria Eugenia Soriano, Vanina Romanello, Tania Zaglia, Rubén Quintana-Cabrera, Martina Semenzato, Roberta Menabò, Veronica Costa, Gabriele Civiletto, Paola Pesce,[...]. Cell Metab 2015
17
Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission.
Oliver C Losón, Zhiyin Song, Hsiuchen Chen, David C Chan. Mol Biol Cell 2013
Oliver C Losón, Zhiyin Song, Hsiuchen Chen, David C Chan. Mol Biol Cell 2013
16
Proteolytic cleavage of Opa1 stimulates mitochondrial inner membrane fusion and couples fusion to oxidative phosphorylation.
Prashant Mishra, Valerio Carelli, Giovanni Manfredi, David C Chan. Cell Metab 2014
Prashant Mishra, Valerio Carelli, Giovanni Manfredi, David C Chan. Cell Metab 2014
16
Mitochondrial dynamics in the regulation of nutrient utilization and energy expenditure.
Marc Liesa, Orian S Shirihai. Cell Metab 2013
Marc Liesa, Orian S Shirihai. Cell Metab 2013
15
Mitochondrial fusion and fission in cell life and death.
Benedikt Westermann. Nat Rev Mol Cell Biol 2010
Benedikt Westermann. Nat Rev Mol Cell Biol 2010
15
During autophagy mitochondria elongate, are spared from degradation and sustain cell viability.
Ligia C Gomes, Giulietta Di Benedetto, Luca Scorrano. Nat Cell Biol 2011
Ligia C Gomes, Giulietta Di Benedetto, Luca Scorrano. Nat Cell Biol 2011
15
New roles for mitochondrial proteases in health, ageing and disease.
Pedro M Quirós, Thomas Langer, Carlos López-Otín. Nat Rev Mol Cell Biol 2015
Pedro M Quirós, Thomas Langer, Carlos López-Otín. Nat Rev Mol Cell Biol 2015
15
Activation of mitochondrial protease OMA1 by Bax and Bak promotes cytochrome c release during apoptosis.
Xian Jiang, Hui Jiang, Zhirong Shen, Xiaodong Wang. Proc Natl Acad Sci U S A 2014
Xian Jiang, Hui Jiang, Zhirong Shen, Xiaodong Wang. Proc Natl Acad Sci U S A 2014
15
Mitochondrial fission contributes to mitochondrial dysfunction and insulin resistance in skeletal muscle.
Huei-Fen Jheng, Pei-Jane Tsai, Syue-Maio Guo, Li-Hua Kuo, Cherng-Shyang Chang, Ih-Jen Su, Chuang-Rung Chang, Yau-Sheng Tsai. Mol Cell Biol 2012
Huei-Fen Jheng, Pei-Jane Tsai, Syue-Maio Guo, Li-Hua Kuo, Cherng-Shyang Chang, Ih-Jen Su, Chuang-Rung Chang, Yau-Sheng Tsai. Mol Cell Biol 2012
14
OPA1 requires mitofusin 1 to promote mitochondrial fusion.
Sara Cipolat, Olga Martins de Brito, Barbara Dal Zilio, Luca Scorrano. Proc Natl Acad Sci U S A 2004
Sara Cipolat, Olga Martins de Brito, Barbara Dal Zilio, Luca Scorrano. Proc Natl Acad Sci U S A 2004
14
14
OPA1 Isoforms in the Hierarchical Organization of Mitochondrial Functions.
Valentina Del Dotto, Prashant Mishra, Sara Vidoni, Mario Fogazza, Alessandra Maresca, Leonardo Caporali, J Michael McCaffery, Martina Cappelletti, Enrico Baruffini, Guy Lenaers,[...]. Cell Rep 2017
Valentina Del Dotto, Prashant Mishra, Sara Vidoni, Mario Fogazza, Alessandra Maresca, Leonardo Caporali, J Michael McCaffery, Martina Cappelletti, Enrico Baruffini, Guy Lenaers,[...]. Cell Rep 2017
14
Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage.
Lorena Griparic, Takayuki Kanazawa, Alexander M van der Bliek. J Cell Biol 2007
Lorena Griparic, Takayuki Kanazawa, Alexander M van der Bliek. J Cell Biol 2007
13
Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis.
Aurélien Olichon, Laurent Baricault, Nicole Gas, Emmanuelle Guillou, Annie Valette, Pascale Belenguer, Guy Lenaers. J Biol Chem 2003
Aurélien Olichon, Laurent Baricault, Nicole Gas, Emmanuelle Guillou, Annie Valette, Pascale Belenguer, Guy Lenaers. J Biol Chem 2003
13
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development.
Hsiuchen Chen, Scott A Detmer, Andrew J Ewald, Erik E Griffin, Scott E Fraser, David C Chan. J Cell Biol 2003
Hsiuchen Chen, Scott A Detmer, Andrew J Ewald, Erik E Griffin, Scott E Fraser, David C Chan. J Cell Biol 2003
13
SLP-2 is required for stress-induced mitochondrial hyperfusion.
Daniel Tondera, Stéphanie Grandemange, Alexis Jourdain, Mariusz Karbowski, Yves Mattenberger, Sébastien Herzig, Sandrine Da Cruz, Pascaline Clerc, Ines Raschke, Carsten Merkwirth,[...]. EMBO J 2009
Daniel Tondera, Stéphanie Grandemange, Alexis Jourdain, Mariusz Karbowski, Yves Mattenberger, Sébastien Herzig, Sandrine Da Cruz, Pascaline Clerc, Ines Raschke, Carsten Merkwirth,[...]. EMBO J 2009
13
The short variant of the mitochondrial dynamin OPA1 maintains mitochondrial energetics and cristae structure.
Hakjoo Lee, Sylvia B Smith, Yisang Yoon. J Biol Chem 2017
Hakjoo Lee, Sylvia B Smith, Yisang Yoon. J Biol Chem 2017
13
Oma1, a novel membrane-bound metallopeptidase in mitochondria with activities overlapping with the m-AAA protease.
Michael Kaser, Melanie Kambacheld, Brigitte Kisters-Woike, Thomas Langer. J Biol Chem 2003
Michael Kaser, Melanie Kambacheld, Brigitte Kisters-Woike, Thomas Langer. J Biol Chem 2003
13
Ablation of the stress protease OMA1 protects against heart failure in mice.
Rebeca Acin-Perez, Ana Victoria Lechuga-Vieco, Maria Del Mar Muñoz, Rocío Nieto-Arellano, Carlos Torroja, Fátima Sánchez-Cabo, Concepción Jiménez, Andrés González-Guerra, Isabel Carrascoso, Cristiane Benincá,[...]. Sci Transl Med 2018
Rebeca Acin-Perez, Ana Victoria Lechuga-Vieco, Maria Del Mar Muñoz, Rocío Nieto-Arellano, Carlos Torroja, Fátima Sánchez-Cabo, Concepción Jiménez, Andrés González-Guerra, Isabel Carrascoso, Cristiane Benincá,[...]. Sci Transl Med 2018
31
Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria.
Carsten Merkwirth, Sascha Dargazanli, Takashi Tatsuta, Stefan Geimer, Beatrix Löwer, F Thomas Wunderlich, Jürgen-Christoph von Kleist-Retzow, Ari Waisman, Benedikt Westermann, Thomas Langer. Genes Dev 2008
Carsten Merkwirth, Sascha Dargazanli, Takashi Tatsuta, Stefan Geimer, Beatrix Löwer, F Thomas Wunderlich, Jürgen-Christoph von Kleist-Retzow, Ari Waisman, Benedikt Westermann, Thomas Langer. Genes Dev 2008
12
Fusion and fission: interlinked processes critical for mitochondrial health.
David C Chan. Annu Rev Genet 2012
David C Chan. Annu Rev Genet 2012
12
Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization.
Ann Cassidy-Stone, Jerry E Chipuk, Elena Ingerman, Cheng Song, Choong Yoo, Tomomi Kuwana, Mark J Kurth, Jared T Shaw, Jenny E Hinshaw, Douglas R Green,[...]. Dev Cell 2008
Ann Cassidy-Stone, Jerry E Chipuk, Elena Ingerman, Cheng Song, Choong Yoo, Tomomi Kuwana, Mark J Kurth, Jared T Shaw, Jenny E Hinshaw, Douglas R Green,[...]. Dev Cell 2008
12
Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation.
Angelika S Rambold, Brenda Kostelecky, Natalie Elia, Jennifer Lippincott-Schwartz. Proc Natl Acad Sci U S A 2011
Angelika S Rambold, Brenda Kostelecky, Natalie Elia, Jennifer Lippincott-Schwartz. Proc Natl Acad Sci U S A 2011
12
Metabolism. AMP-activated protein kinase mediates mitochondrial fission in response to energy stress.
Erin Quan Toyama, Sébastien Herzig, Julien Courchet, Tommy L Lewis, Oliver C Losón, Kristina Hellberg, Nathan P Young, Hsiuchen Chen, Franck Polleux, David C Chan,[...]. Science 2016
Erin Quan Toyama, Sébastien Herzig, Julien Courchet, Tommy L Lewis, Oliver C Losón, Kristina Hellberg, Nathan P Young, Hsiuchen Chen, Franck Polleux, David C Chan,[...]. Science 2016
11
The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells.
Shilpa Gandre-Babbe, Alexander M van der Bliek. Mol Biol Cell 2008
Shilpa Gandre-Babbe, Alexander M van der Bliek. Mol Biol Cell 2008
11
Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells.
E Smirnova, L Griparic, D L Shurland, A M van der Bliek. Mol Biol Cell 2001
E Smirnova, L Griparic, D L Shurland, A M van der Bliek. Mol Biol Cell 2001
11
Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death.
J Thomas Cribbs, Stefan Strack. EMBO Rep 2007
J Thomas Cribbs, Stefan Strack. EMBO Rep 2007
11
Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling.
Sara Cipolat, Tomasz Rudka, Dieter Hartmann, Veronica Costa, Lutgarde Serneels, Katleen Craessaerts, Kristine Metzger, Christian Frezza, Wim Annaert, Luciano D'Adamio,[...]. Cell 2006
Sara Cipolat, Tomasz Rudka, Dieter Hartmann, Veronica Costa, Lutgarde Serneels, Katleen Craessaerts, Kristine Metzger, Christian Frezza, Wim Annaert, Luciano D'Adamio,[...]. Cell 2006
11
Mito-Morphosis: Mitochondrial Fusion, Fission, and Cristae Remodeling as Key Mediators of Cellular Function.
Lena Pernas, Luca Scorrano. Annu Rev Physiol 2016
Lena Pernas, Luca Scorrano. Annu Rev Physiol 2016
11
ClpP mediates activation of a mitochondrial unfolded protein response in C. elegans.
Cole M Haynes, Kseniya Petrova, Cristina Benedetti, Yun Yang, David Ron. Dev Cell 2007
Cole M Haynes, Kseniya Petrova, Cristina Benedetti, Yun Yang, David Ron. Dev Cell 2007
11
Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy.
C Delettre, G Lenaers, J M Griffoin, N Gigarel, C Lorenzo, P Belenguer, L Pelloquin, J Grosgeorge, C Turc-Carel, E Perret,[...]. Nat Genet 2000
C Delettre, G Lenaers, J M Griffoin, N Gigarel, C Lorenzo, P Belenguer, L Pelloquin, J Grosgeorge, C Turc-Carel, E Perret,[...]. Nat Genet 2000
11
OMA1 mediates OPA1 proteolysis and mitochondrial fragmentation in experimental models of ischemic kidney injury.
Xiao Xiao, Yanzhong Hu, Pedro M Quirós, Qingqing Wei, Carlos López-Otín, Zheng Dong. Am J Physiol Renal Physiol 2014
Xiao Xiao, Yanzhong Hu, Pedro M Quirós, Qingqing Wei, Carlos López-Otín, Zheng Dong. Am J Physiol Renal Physiol 2014
16
Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability.
Iryna Bohovych, Mario R Fernandez, Jennifer J Rahn, Krista D Stackley, Jennifer E Bestman, Annadurai Anandhan, Rodrigo Franco, Steven M Claypool, Robert E Lewis, Sherine S L Chan,[...]. Sci Rep 2015
Iryna Bohovych, Mario R Fernandez, Jennifer J Rahn, Krista D Stackley, Jennifer E Bestman, Annadurai Anandhan, Rodrigo Franco, Steven M Claypool, Robert E Lewis, Sherine S L Chan,[...]. Sci Rep 2015
30
A mitochondrial specific stress response in mammalian cells.
Quan Zhao, Jianghui Wang, Ilya V Levichkin, Stan Stasinopoulos, Michael T Ryan, Nicholas J Hoogenraad. EMBO J 2002
Quan Zhao, Jianghui Wang, Ilya V Levichkin, Stan Stasinopoulos, Michael T Ryan, Nicholas J Hoogenraad. EMBO J 2002
10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.