A citation-based method for searching scientific literature

Mohammed Akli Ayoub, Dora Angelicheva, David Vile, David Chandler, Bharti Morar, Juleen A Cavanaugh, Peter M Visscher, Assen Jablensky, Kevin D G Pfleger, Luba Kalaydjieva. PLoS One 2012
Times Cited: 42







List of co-cited articles
579 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Clustered coding variants in the glutamate receptor complexes of individuals with schizophrenia and bipolar disorder.
René A W Frank, Allan F McRae, Andrew J Pocklington, Louie N van de Lagemaat, Pau Navarro, Mike D R Croning, Noboru H Komiyama, Sophie J Bradley, R A John Challiss, J Douglas Armstrong,[...]. PLoS One 2011
44
47

Chemical modulation of mutant mGlu1 receptors derived from deleterious GRM1 mutations found in schizophrenics.
Hyekyung P Cho, Pedro M Garcia-Barrantes, John T Brogan, Corey R Hopkins, Colleen M Niswender, Alice L Rodriguez, Daryl F Venable, Ryan D Morrison, Michael Bubser, J Scott Daniels,[...]. ACS Chem Biol 2014
35
54

Metabotropic glutamate receptors: physiology, pharmacology, and disease.
Colleen M Niswender, P Jeffrey Conn. Annu Rev Pharmacol Toxicol 2010
33

Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial.
Sandeep T Patil, Lu Zhang, Ferenc Martenyi, Stephen L Lowe, Kimberley A Jackson, Boris V Andreev, Alla S Avedisova, Leonid M Bardenstein, Issak Y Gurovich, Margarita A Morozova,[...]. Nat Med 2007
780
26

Biased mGlu5-Positive Allosteric Modulators Provide In Vivo Efficacy without Potentiating mGlu5 Modulation of NMDAR Currents.
Jerri M Rook, Zixiu Xiang, Xiaohui Lv, Ayan Ghoshal, Jonathan W Dickerson, Thomas M Bridges, Kari A Johnson, Daniel J Foster, Karen J Gregory, Paige N Vinson,[...]. Neuron 2015
81
26

Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator.
Huixian Wu, Chong Wang, Karen J Gregory, Gye Won Han, Hyekyung P Cho, Yan Xia, Colleen M Niswender, Vsevolod Katritch, Jens Meiler, Vadim Cherezov,[...]. Science 2014
350
23


Mechanism based neurotoxicity of mGlu5 positive allosteric modulators--development challenges for a promising novel antipsychotic target.
Sophie Parmentier-Batteur, Peter H Hutson, Karsten Menzel, Jason M Uslaner, Britta A Mattson, Julie A O'Brien, Brian C Magliaro, Thomas Forest, Craig A Stump, Robert M Tynebor,[...]. Neuropharmacology 2014
66
23

Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia.
P Jeffrey Conn, Craig W Lindsley, Carrie K Jones. Trends Pharmacol Sci 2009
264
21

"Molecular switches" on mGluR allosteric ligands that modulate modes of pharmacology.
Michael R Wood, Corey R Hopkins, John T Brogan, P Jeffrey Conn, Craig W Lindsley. Biochemistry 2011
126
21

Selective actions of novel allosteric modulators reveal functional heteromers of metabotropic glutamate receptors in the CNS.
Shen Yin, Meredith J Noetzel, Kari A Johnson, Rocio Zamorano, Nidhi Jalan-Sakrikar, Karen J Gregory, P Jeffrey Conn, Colleen M Niswender. J Neurosci 2014
80
21

Positive allosteric modulators of metabotropic glutamate 1 receptor: characterization, mechanism of action, and binding site.
F Knoflach, V Mutel, S Jolidon, J N Kew, P Malherbe, E Vieira, J Wichmann, J A Kemp. Proc Natl Acad Sci U S A 2001
196
19

Disruption of prepulse inhibition in mice lacking mGluR1.
S A Brody, F Conquet, M A Geyer. Eur J Neurosci 2003
68
19

Fluorinated 9H-xanthene-9-carboxylic acid oxazol-2-yl-amides as potent, orally available mGlu1 receptor enhancers.
Eric Vieira, Jörg Huwyler, Synèse Jolidon, Frédéric Knoflach, Vincent Mutel, Jürgen Wichmann. Bioorg Med Chem Lett 2009
26
30

Unique signaling profiles of positive allosteric modulators of metabotropic glutamate receptor subtype 5 determine differences in in vivo activity.
Jerri M Rook, Meredith J Noetzel, Wendy A Pouliot, Thomas M Bridges, Paige N Vinson, Hyekyung P Cho, Ya Zhou, Rocco D Gogliotti, Jason T Manka, Karen J Gregory,[...]. Biol Psychiatry 2013
76
19



An mGlu5-Positive Allosteric Modulator Rescues the Neuroplasticity Deficits in a Genetic Model of NMDA Receptor Hypofunction in Schizophrenia.
Darrick T Balu, Yan Li, Shunsuke Takagi, Kendall Taylor Presti, Teniel S Ramikie, Jerri M Rook, Carrie K Jones, Craig W Lindsley, P Jeffrey Conn, Vadim Y Bolshakov,[...]. Neuropsychopharmacology 2016
40
20


A multicenter, inpatient, phase 2, double-blind, placebo-controlled dose-ranging study of LY2140023 monohydrate in patients with DSM-IV schizophrenia.
Bruce J Kinon, Lu Zhang, Brian A Millen, Olawale O Osuntokun, Judy E Williams, Sara Kollack-Walker, Kimberley Jackson, Ludmila Kryzhanovskaya, Natalia Jarkova. J Clin Psychopharmacol 2011
172
16


Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders.
P Jeffrey Conn, Arthur Christopoulos, Craig W Lindsley. Nat Rev Drug Discov 2009
746
16



mGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learning.
Jennifer E Ayala, Yelin Chen, Jessica L Banko, Douglas J Sheffler, Richard Williams, Alexandra N Telk, Noreen L Watson, Zixiu Xiang, Yongqin Zhang, Paulianda J Jones,[...]. Neuropsychopharmacology 2009
167
16

Unique antipsychotic activities of the selective metabotropic glutamate receptor 1 allosteric antagonist 2-cyclopropyl-5-[1-(2-fluoro-3-pyridinyl)-5-methyl-1H-1,2,3-triazol-4-yl]-2,3-dihydro-1H-isoindol-1-one.
Akio Satow, Gentaroh Suzuki, Shunsuke Maehara, Hirohiko Hikichi, Takeshi Murai, Takashi Murai, Hiroko Kawagoe-Takaki, Mikiko Hata, Satoru Ito, Satoshi Ozaki,[...]. J Pharmacol Exp Ther 2009
41
17

A new approach to analyze cell surface protein complexes reveals specific heterodimeric metabotropic glutamate receptors.
Etienne Doumazane, Pauline Scholler, Jurriaan M Zwier, Eric Trinquet, Philippe Rondard, Jean-Philippe Pin. FASEB J 2011
195
16

Characterization of the novel positive allosteric modulator of the metabotropic glutamate receptor 4 ADX88178 in rodent models of neuropsychiatric disorders.
Mikhail Kalinichev, Emmanuel Le Poul, Christelle Boléa, Françoise Girard, Brice Campo, Massimiliano Fonsi, Isabelle Royer-Urios, Susan E Browne, Jason M Uslaner, Matthew J Davis,[...]. J Pharmacol Exp Ther 2014
47
16

AZD8529, a positive allosteric modulator at the mGluR2 receptor, does not improve symptoms in schizophrenia: A proof of principle study.
Robert E Litman, Mark A Smith, James J Doherty, Alan Cross, Shane Raines, Lev Gertsik, Stephen R Zukin. Schizophr Res 2016
44
16

Metabotropic glutamate receptors: from the workbench to the bedside.
F Nicoletti, J Bockaert, G L Collingridge, P J Conn, F Ferraguti, D D Schoepp, J T Wroblewski, J P Pin. Neuropharmacology 2011
399
14



Discovery of novel allosteric modulators of metabotropic glutamate receptor subtype 5 reveals chemical and functional diversity and in vivo activity in rat behavioral models of anxiolytic and antipsychotic activity.
Alice L Rodriguez, Mark D Grier, Carrie K Jones, Elizabeth J Herman, Alexander S Kane, Randy L Smith, Richard Williams, Ya Zhou, Joy E Marlo, Emily L Days,[...]. Mol Pharmacol 2010
141
14

A novel class of positive allosteric modulators of metabotropic glutamate receptor subtype 1 interact with a site distinct from that of negative allosteric modulators.
Kamondanai Hemstapat, Tomas de Paulis, Yelin Chen, Ashley E Brady, Vandana K Grover, David Alagille, Gilles D Tamagnan, P Jeffrey Conn. Mol Pharmacol 2006
52
14

A novel class of succinimide-derived negative allosteric modulators of metabotropic glutamate receptor subtype 1 provides insight into a disconnect in activity between the rat and human receptors.
Hyekyung P Cho, Darren W Engers, Daryl F Venable, Colleen M Niswender, Craig W Lindsley, P Jeffrey Conn, Kyle A Emmitte, Alice L Rodriguez. ACS Chem Neurosci 2014
26
23

A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models.
Gene G Kinney, Julie A O'Brien, Wei Lemaire, Maryann Burno, Denise J Bickel, Michelle K Clements, Tsing-Bau Chen, David D Wisnoski, Craig W Lindsley, Philip R Tiller,[...]. J Pharmacol Exp Ther 2005
244
14

Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice.
Ruggero Galici, Carrie K Jones, Kamondanai Hemstapat, Yi Nong, Nicholas G Echemendia, Lilly C Williams, Tomas de Paulis, P Jeffrey Conn. J Pharmacol Exp Ther 2006
128
14


Metabotropic glutamate subtype 5 receptors modulate locomotor activity and sensorimotor gating in rodents.
Gene G Kinney, Maryann Burno, Una C Campbell, Lisa M Hernandez, Dana Rodriguez, Linda J Bristow, P Jeffrey Conn. J Pharmacol Exp Ther 2003
181
14


Assessment of a prepulse inhibition deficit in a mutant mouse lacking mGlu5 receptors.
S A Brody, S C Dulawa, F Conquet, M A Geyer. Mol Psychiatry 2004
113
14

Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain.
Andrew S Doré, Krzysztof Okrasa, Jayesh C Patel, Maria Serrano-Vega, Kirstie Bennett, Robert M Cooke, James C Errey, Ali Jazayeri, Samir Khan, Ben Tehan,[...]. Nature 2014
279
14


Discovery of VU0409551/JNJ-46778212: An mGlu5 Positive Allosteric Modulator Clinical Candidate Targeting Schizophrenia.
Susana Conde-Ceide, Carlos M Martínez-Viturro, Jesús Alcázar, Pedro M Garcia-Barrantes, Hilde Lavreysen, Claire Mackie, Paige N Vinson, Jerri M Rook, Thomas M Bridges, J Scott Daniels,[...]. ACS Med Chem Lett 2015
33
18

Lead optimization of the VU0486321 series of mGlu1 PAMs. Part 1: SAR of modifications to the central aryl core.
Pedro M Garcia-Barrantes, Hyekyung P Cho, Anna L Blobaum, Colleen M Niswender, P Jeffrey Conn, Craig W Lindsley. Bioorg Med Chem Lett 2015
8
75

Metabotropic glutamate receptor 3 activation is required for long-term depression in medial prefrontal cortex and fear extinction.
Adam G Walker, Cody J Wenthur, Zixiu Xiang, Jerri M Rook, Kyle A Emmitte, Colleen M Niswender, Craig W Lindsley, P Jeffrey Conn. Proc Natl Acad Sci U S A 2015
61
14

The antipsychotic-like effects of positive allosteric modulators of metabotropic glutamate mGlu4 receptors in rodents.
Anna Sławińska, Joanna M Wierońska, Katarzyna Stachowicz, Marcin Marciniak, Magdalena Lasoń-Tyburkiewicz, Piotr Gruca, Mariusz Papp, Magdalena Kusek, Krzysztof Tokarski, Darío Doller,[...]. Br J Pharmacol 2013
36
16

Targeting metabotropic glutamate receptors for novel treatments of schizophrenia.
James Maksymetz, Sean P Moran, P Jeffrey Conn. Mol Brain 2017
65
14


Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
J H Krystal, L P Karper, J P Seibyl, G K Freeman, R Delaney, J D Bremner, G R Heninger, M B Bowers, D S Charney. Arch Gen Psychiatry 1994
11


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.