A citation-based method for searching scientific literature

Jeremy B Samon, Mireia Castillo-Martin, Michael Hadler, Alberto Ambesi-Impiobato, Elisabeth Paietta, Janis Racevskis, Peter H Wiernik, Jacob M Rowe, John Jakubczak, Sophia Randolph, Carlos Cordon-Cardo, Adolfo A Ferrando. Mol Cancer Ther 2012
Times Cited: 83







List of co-cited articles
1613 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster. Science 2004
54

Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia.
Pedro J Real, Valeria Tosello, Teresa Palomero, Mireia Castillo, Eva Hernando, Elisa de Stanchina, Maria Luisa Sulis, Kelly Barnes, Catherine Sawai, Irene Homminga,[...]. Nat Med 2009
323
37

Evaluation of selective gamma-secretase inhibitor PF-03084014 for its antitumor efficacy and gastrointestinal safety to guide optimal clinical trial design.
Ping Wei, Marlena Walls, Ming Qiu, Richard Ding, Robert H Denlinger, Anthony Wong, Kosta Tsaparikos, Jitesh P Jani, Natilie Hosea, Michelle Sands,[...]. Mol Cancer Ther 2010
143
37

Therapeutic antibody targeting of individual Notch receptors.
Yan Wu, Carol Cain-Hom, Lisa Choy, Thijs J Hagenbeek, Gladys P de Leon, Yongmei Chen, David Finkle, Rayna Venook, Xiumin Wu, John Ridgway,[...]. Nature 2010
516
34

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia.
Teresa Palomero, Maria Luisa Sulis, Maria Cortina, Pedro J Real, Kelly Barnes, Maria Ciofani, Esther Caparros, Jean Buteau, Kristy Brown, Sherrie L Perkins,[...]. Nat Med 2007
660
33

Direct inhibition of the NOTCH transcription factor complex.
Raymond E Moellering, Melanie Cornejo, Tina N Davis, Cristina Del Bianco, Jon C Aster, Stephen C Blacklow, Andrew L Kung, D Gary Gilliland, Gregory L Verdine, James E Bradner. Nature 2009
559
30

TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms.
L W Ellisen, J Bird, D C West, A L Soreng, T C Reynolds, S D Smith, J Sklar. Cell 1991
30

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
Jennifer O'Neil, Jonathan Grim, Peter Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James Hardwick, Markus Welcker, Jules P Meijerink, Rob Pieters,[...]. J Exp Med 2007
494
26

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma.
Andrew P Weng, John M Millholland, Yumi Yashiro-Ohtani, Marie Laure Arcangeli, Arthur Lau, Carol Wai, Cristina Del Bianco, Carlos G Rodriguez, Hong Sai, John Tobias,[...]. Genes Dev 2006
627
26

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth.
Teresa Palomero, Wei Keat Lim, Duncan T Odom, Maria Luisa Sulis, Pedro J Real, Adam Margolin, Kelly C Barnes, Jennifer O'Neil, Donna Neuberg, Andrew P Weng,[...]. Proc Natl Acad Sci U S A 2006
592
21

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells.
Johan H van Es, Marielle E van Gijn, Orbicia Riccio, Maaike van den Born, Marc Vooijs, Harry Begthel, Miranda Cozijnsen, Sylvie Robine, Doug J Winton, Freddy Radtke,[...]. Nature 2005
21

An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.
Birgit Knoechel, Justine E Roderick, Kaylyn E Williamson, Jiang Zhu, Jens G Lohr, Matthew J Cotton, Shawn M Gillespie, Daniel Fernandez, Manching Ku, Hongfang Wang,[...]. Nat Genet 2014
236
20

Phase I pharmacologic and pharmacodynamic study of the gamma secretase (Notch) inhibitor MK-0752 in adult patients with advanced solid tumors.
Ian Krop, Tim Demuth, Tina Guthrie, Patrick Y Wen, Warren P Mason, Prakash Chinnaiyan, Nicholas Butowski, Morris D Groves, Santosh Kesari, Steven J Freedman,[...]. J Clin Oncol 2012
214
19

A Phase 1 study of the novel gamma-secretase inhibitor PF-03084014 in patients with T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma.
C Papayannidis, D J DeAngelo, W Stock, B Huang, M N Shaik, R Cesari, X Zheng, J M Reynolds, P A English, M Ozeck,[...]. Blood Cancer J 2015
71
22

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.
Jinghui Zhang, Li Ding, Linda Holmfeldt, Gang Wu, Sue L Heatley, Debbie Payne-Turner, John Easton, Xiang Chen, Jianmin Wang, Michael Rusch,[...]. Nature 2012
18

Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation.
Joseph Milano, Jenny McKay, Claude Dagenais, Linda Foster-Brown, Francois Pognan, Reto Gadient, Robert T Jacobs, Anna Zacco, Barry Greenberg, Paul J Ciaccio. Toxicol Sci 2004
412
18

Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors.
Miguel Aste-Amézaga, Ningyan Zhang, Janet E Lineberger, Beth A Arnold, Timothy J Toner, Mingcheng Gu, Lingyi Huang, Salvatore Vitelli, Kim T Vo, Peter Haytko,[...]. PLoS One 2010
130
18


Targeting the Notch1 and mTOR pathways in a mouse T-ALL model.
Kathleen Cullion, Kyle M Draheim, Nicole Hermance, Jennifer Tammam, Vishva M Sharma, Christopher Ware, George Nikov, Veena Krishnamoorthy, Pradip K Majumder, Michelle A Kelliher. Blood 2009
106
16

Therapeutic antibody targeting of Notch1 in T-acute lymphoblastic leukemia xenografts.
V Agnusdei, S Minuzzo, C Frasson, A Grassi, F Axelrod, S Satyal, A Gurney, T Hoey, E Seganfreddo, G Basso,[...]. Leukemia 2014
82
17

Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc.
Vishva Mitra Sharma, Jennifer A Calvo, Kyle M Draheim, Leslie A Cunningham, Nicole Hermance, Levi Beverly, Veena Krishnamoorthy, Manoj Bhasin, Anthony J Capobianco, Michelle A Kelliher. Mol Cell Biol 2006
207
15

Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.
Tomas Vilimas, Joaquina Mascarenhas, Teresa Palomero, Malay Mandal, Silvia Buonamici, Fanyong Meng, Benjamín Thompson, Christina Spaulding, Sami Macaroun, Maria-Luisa Alegre,[...]. Nat Med 2007
249
15

Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia.
Adolfo A Ferrando, Donna S Neuberg, Jane Staunton, Mignon L Loh, Christine Huard, Susana C Raimondi, Fred G Behm, Ching Hon Pui, James R Downing, D Gary Gilliland,[...]. Cancer Cell 2002
782
15

High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia.
Alejandro Gutierrez, Takaomi Sanda, Ruta Grebliunaite, Arkaitz Carracedo, Leonardo Salmena, Yebin Ahn, Suzanne Dahlberg, Donna Neuberg, Lisa A Moreau, Stuart S Winter,[...]. Blood 2009
318
15

A Phase I, dose-finding study in patients with advanced solid malignancies of the oral γ-secretase inhibitor PF-03084014.
Wells A Messersmith, Geoffrey I Shapiro, James M Cleary, Antonio Jimeno, Arvind Dasari, Bo Huang, M Naveed Shaik, Rossano Cesari, Xianxian Zheng, Jennifer M Reynolds,[...]. Clin Cancer Res 2015
126
15

The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia.
Benjamin J Thompson, Silvia Buonamici, Maria Luisa Sulis, Teresa Palomero, Tomas Vilimas, Giuseppe Basso, Adolfo Ferrando, Iannis Aifantis. J Exp Med 2007
348
14


Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia.
Elaine Coustan-Smith, Charles G Mullighan, Mihaela Onciu, Frederick G Behm, Susana C Raimondi, Deqing Pei, Cheng Cheng, Xiaoping Su, Jeffrey E Rubnitz, Giuseppe Basso,[...]. Lancet Oncol 2009
558
13

Inhibition of NOTCH signaling by gamma secretase inhibitor engages the RB pathway and elicits cell cycle exit in T-cell acute lymphoblastic leukemia cells.
Sudhir S Rao, Jennifer O'Neil, Cole D Liberator, James S Hardwick, Xudong Dai, Theresa Zhang, Edyta Tyminski, Jing Yuan, Nancy E Kohl, Victoria M Richon,[...]. Cancer Res 2009
107
13

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain.
B De Strooper, W Annaert, P Cupers, P Saftig, K Craessaerts, J S Mumm, E H Schroeter, V Schrijvers, M S Wolfe, W J Ray,[...]. Nature 1999
13

Notch1 inhibition targets the leukemia-initiating cells in a Tal1/Lmo2 mouse model of T-ALL.
Jessica Tatarek, Kathleen Cullion, Todd Ashworth, Rachel Gerstein, Jon C Aster, Michelle A Kelliher. Blood 2011
70
15

Biomarker and pharmacologic evaluation of the γ-secretase inhibitor PF-03084014 in breast cancer models.
Cathy C Zhang, Adam Pavlicek, Qin Zhang, Maruja E Lira, Cory L Painter, Zhengming Yan, Xianxian Zheng, Nathan V Lee, Mark Ozeck, Ming Qiu,[...]. Clin Cancer Res 2012
56
19

The role of the PTEN/AKT Pathway in NOTCH1-induced leukemia.
Teresa Palomero, Maria Dominguez, Adolfo A Ferrando. Cell Cycle 2008
178
13

Phase I study of RO4929097, a gamma secretase inhibitor of Notch signaling, in patients with refractory metastatic or locally advanced solid tumors.
Anthony W Tolcher, Wells A Messersmith, Stanislaw M Mikulski, Kyriakos P Papadopoulos, Eunice L Kwak, Darlene G Gibbon, Amita Patnaik, Gerald S Falchook, Arvind Dasari, Geoffrey I Shapiro,[...]. J Clin Oncol 2012
175
13

Toward a NOTCH1/FBXW7/RAS/PTEN-based oncogenetic risk classification of adult T-cell acute lymphoblastic leukemia: a Group for Research in Adult Acute Lymphoblastic Leukemia study.
Amélie Trinquand, Aline Tanguy-Schmidt, Raouf Ben Abdelali, Jérôme Lambert, Kheira Beldjord, Etienne Lengliné, Noémie De Gunzburg, Dominique Payet-Bornet, Ludovic Lhermitte, Hossein Mossafa,[...]. J Clin Oncol 2013
150
13

Targeting Notch signaling with a Notch2/Notch3 antagonist (tarextumab) inhibits tumor growth and decreases tumor-initiating cell frequency.
Wan-Ching Yen, Marcus M Fischer, Fumiko Axelrod, Christopher Bond, Jennifer Cain, Belinda Cancilla, William R Henner, Rene Meisner, Aaron Sato, Jalpa Shah,[...]. Clin Cancer Res 2015
162
13

Synergistic antileukemic therapies in NOTCH1-induced T-ALL.
Marta Sanchez-Martin, Alberto Ambesi-Impiombato, Yue Qin, Daniel Herranz, Mukesh Bansal, Tiziana Girardi, Elisabeth Paietta, Martin S Tallman, Jacob M Rowe, Kim De Keersmaecker,[...]. Proc Natl Acad Sci U S A 2017
41
26

The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia.
Lluis Espinosa, Severine Cathelin, Teresa D'Altri, Thomas Trimarchi, Alexander Statnikov, Jordi Guiu, Veronica Rodilla, Julia Inglés-Esteve, Josep Nomdedeu, Beatriz Bellosillo,[...]. Cancer Cell 2010
201
12

Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia.
C Graux, J Cools, C Melotte, H Quentmeier, A Ferrando, R Levine, J R Vermeesch, M Stul, B Dutta, N Boeckx,[...]. Nat Genet 2004
287
12

Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis.
John Ridgway, Gu Zhang, Yan Wu, Scott Stawicki, Wei-Ching Liang, Yvan Chanthery, Joe Kowalski, Ryan J Watts, Christopher Callahan, Ian Kasman,[...]. Nature 2006
735
12

Deficient T cell fate specification in mice with an induced inactivation of Notch1.
F Radtke, A Wilson, G Stark, M Bauer, J van Meerwijk, H R MacDonald, M Aguet. Immunity 1999
12

High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling.
Hind Medyouf, Samuel Gusscott, Hongfang Wang, Jen-Chieh Tseng, Carol Wai, Oksana Nemirovsky, Andreas Trumpp, Francoise Pflumio, Joan Carboni, Marco Gottardis,[...]. J Exp Med 2011
121
12

Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2.
Orbicia Riccio, Marielle E van Gijn, April C Bezdek, Luca Pellegrinet, Johan H van Es, Ursula Zimber-Strobl, Lothar J Strobl, Tasuku Honjo, Hans Clevers, Freddy Radtke. EMBO Rep 2008
289
12

Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition.
Roger A Habets, Charles E de Bock, Lutgarde Serneels, Inge Lodewijckx, Delphine Verbeke, David Nittner, Rajeshwar Narlawar, Sofie Demeyer, James Dooley, Adrian Liston,[...]. Sci Transl Med 2019
47
21

NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols.
L Zuurbier, I Homminga, V Calvert, M L te Winkel, J G C A M Buijs-Gladdines, C Kooi, W K Smits, E Sonneveld, A J P Veerman, W A Kamps,[...]. Leukemia 2010
99
10


Preclinical profile of a potent gamma-secretase inhibitor targeting notch signaling with in vivo efficacy and pharmacodynamic properties.
Leopoldo Luistro, Wei He, Melissa Smith, Kathryn Packman, Maria Vilenchik, Daisy Carvajal, John Roberts, James Cai, Windy Berkofsky-Fessler, Holly Hilton,[...]. Cancer Res 2009
146
10

Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors.
Anne F Schott, Melissa D Landis, Gabriela Dontu, Kent A Griffith, Rachel M Layman, Ian Krop, Lacey A Paskett, Helen Wong, Lacey E Dobrolecki, Michael T Lewis,[...]. Clin Cancer Res 2013
156
10

CSL-MAML-dependent Notch1 signaling controls T lineage-specific IL-7R{alpha} gene expression in early human thymopoiesis and leukemia.
Sara González-García, Marina García-Peydró, Enrique Martín-Gayo, Esteban Ballestar, Manel Esteller, Rafael Bornstein, José Luis de la Pompa, Adolfo A Ferrando, María L Toribio. J Exp Med 2009
106
10

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia.
Xose S Puente, Magda Pinyol, Víctor Quesada, Laura Conde, Gonzalo R Ordóñez, Neus Villamor, Georgia Escaramis, Pedro Jares, Sílvia Beà, Marcos González-Díaz,[...]. Nature 2011
10


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.