A citation-based method for searching scientific literature

Takafumi Tasaki, Shashikanth M Sriram, Kyong Soo Park, Yong Tae Kwon. Annu Rev Biochem 2012
Times Cited: 254







List of co-cited articles
679 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


The N-end rule pathway and regulation by proteolysis.
Alexander Varshavsky. Protein Sci 2011
456
44


N-degron and C-degron pathways of protein degradation.
Alexander Varshavsky. Proc Natl Acad Sci U S A 2019
221
39

An N-end rule pathway that recognizes proline and destroys gluconeogenic enzymes.
Shun-Jia Chen, Xia Wu, Brandon Wadas, Jang-Hyun Oh, Alexander Varshavsky. Science 2017
112
30

N-terminal acetylation of cellular proteins creates specific degradation signals.
Cheol-Sang Hwang, Anna Shemorry, Alexander Varshavsky. Science 2010
442
30

The eukaryotic N-end rule pathway: conserved mechanisms and diverse functions.
Daniel J Gibbs, Jaume Bacardit, Andreas Bachmair, Michael J Holdsworth. Trends Cell Biol 2014
134
27

The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments.
Konstantin I Piatkov, Christopher S Brower, Alexander Varshavsky. Proc Natl Acad Sci U S A 2012
102
23

Control of protein quality and stoichiometries by N-terminal acetylation and the N-end rule pathway.
Anna Shemorry, Cheol-Sang Hwang, Alexander Varshavsky. Mol Cell 2013
200
21

The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators.
Rong-Gui Hu, Jun Sheng, Xin Qi, Zhenming Xu, Terry T Takahashi, Alexander Varshavsky. Nature 2005
226
21

An essential role of N-terminal arginylation in cardiovascular development.
Yong Tae Kwon, Anna S Kashina, Ilia V Davydov, Rong-Gui Hu, Jee Young An, Jai Wha Seo, Fangyong Du, Alexander Varshavsky. Science 2002
248
21

Formyl-methionine as an N-degron of a eukaryotic N-end rule pathway.
Jeong-Mok Kim, Ok-Hee Seok, Shinyeong Ju, Ji-Eun Heo, Jeonghun Yeom, Da-Som Kim, Joo-Yeon Yoo, Alexander Varshavsky, Cheolju Lee, Cheol-Sang Hwang. Science 2018
48
41

The N-terminal methionine of cellular proteins as a degradation signal.
Heon-Ki Kim, Ryu-Ryun Kim, Jang-Hyun Oh, Hanna Cho, Alexander Varshavsky, Cheol-Sang Hwang. Cell 2014
121
19

Neurodegeneration-associated protein fragments as short-lived substrates of the N-end rule pathway.
Christopher S Brower, Konstantin I Piatkov, Alexander Varshavsky. Mol Cell 2013
79
24

A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons.
Takafumi Tasaki, Lubbertus C F Mulder, Akihiro Iwamatsu, Min Jae Lee, Ilia V Davydov, Alexander Varshavsky, Mark Muesing, Yong Tae Kwon. Mol Cell Biol 2005
232
17

Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding.
Hyunjoo Cha-Molstad, Ki Sa Sung, Joonsung Hwang, Kyoung A Kim, Ji Eun Yu, Young Dong Yoo, Jun Min Jang, Dong Hoon Han, Michael Molstad, Jung Gi Kim,[...]. Nat Cell Biol 2015
143
17

Plant cysteine oxidases are dioxygenases that directly enable arginyl transferase-catalysed arginylation of N-end rule targets.
Mark D White, Maria Klecker, Richard J Hopkinson, Daan A Weits, Carolin Mueller, Christin Naumann, Rebecca O'Neill, James Wickens, Jiayu Yang, Jonathan C Brooks-Bartlett,[...]. Nat Commun 2017
107
16


RGS4 and RGS5 are in vivo substrates of the N-end rule pathway.
Min Jae Lee, Takafumi Tasaki, Kayoko Moroi, Jee Young An, Sadao Kimura, Ilia V Davydov, Yong Tae Kwon. Proc Natl Acad Sci U S A 2005
186
16

A glycine-specific N-degron pathway mediates the quality control of protein N-myristoylation.
Richard T Timms, Zhiqian Zhang, David Y Rhee, J Wade Harper, Itay Koren, Stephen J Elledge. Science 2019
66
24

The degradation signal in a short-lived protein.
A Bachmair, A Varshavsky. Cell 1989
358
15

Homeostatic response to hypoxia is regulated by the N-end rule pathway in plants.
Daniel J Gibbs, Seung Cho Lee, Nurulhikma Md Isa, Silvia Gramuglia, Takeshi Fukao, George W Bassel, Cristina Sousa Correia, Françoise Corbineau, Frederica L Theodoulou, Julia Bailey-Serres,[...]. Nature 2011
384
15

The N-end rule pathway: emerging functions and molecular principles of substrate recognition.
Shashikanth M Sriram, Bo Yeon Kim, Yong Tae Kwon. Nat Rev Mol Cell Biol 2011
137
15


N-terminal arginylation generates a bimodal degron that modulates autophagic proteolysis.
Young Dong Yoo, Su Ran Mun, Chang Hoon Ji, Ki Woon Sung, Keum Young Kang, Ah Jung Heo, Su Hyun Lee, Jee Young An, Joonsung Hwang, Xiang-Qun Xie,[...]. Proc Natl Acad Sci U S A 2018
33
45

Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway.
Cheng Dong, Heng Zhang, Li Li, Wolfram Tempel, Peter Loppnau, Jinrong Min. Nat Chem Biol 2018
50
30


The auto-generated fragment of the Usp1 deubiquitylase is a physiological substrate of the N-end rule pathway.
Konstantin I Piatkov, Luca Colnaghi, Miklos Békés, Alexander Varshavsky, Tony T Huang. Mol Cell 2012
51
25

The N-end rule pathway: from recognition by N-recognins, to destruction by AAA+proteases.
D A Dougan, D Micevski, K N Truscott. Biochim Biophys Acta 2012
85
15

Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases.
Woo Suk Choi, Byung-Cheon Jeong, Yoo Jin Joo, Myeong-Ryeol Lee, Joon Kim, Michael J Eck, Hyun Kyu Song. Nat Struct Mol Biol 2010
101
13

Plant cysteine oxidases control the oxygen-dependent branch of the N-end-rule pathway.
Daan A Weits, Beatrice Giuntoli, Monika Kosmacz, Sandro Parlanti, Hans-Michael Hubberten, Heike Riegler, Rainer Hoefgen, Pierdomenico Perata, Joost T van Dongen, Francesco Licausi. Nat Commun 2014
190
12

Oxygen sensing in plants is mediated by an N-end rule pathway for protein destabilization.
Francesco Licausi, Monika Kosmacz, Daan A Weits, Beatrice Giuntoli, Federico M Giorgi, Laurentius A C J Voesenek, Pierdomenico Perata, Joost T van Dongen. Nature 2011
404
12

N-Terminal Acetylation-Targeted N-End Rule Proteolytic System: The Ac/N-End Rule Pathway.
Kang-Eun Lee, Ji-Eun Heo, Jeong-Mok Kim, Cheol-Sang Hwang. Mol Cells 2016
40
30

First Things First: Vital Protein Marks by N-Terminal Acetyltransferases.
Henriette Aksnes, Adrian Drazic, Michaël Marie, Thomas Arnesen. Trends Biochem Sci 2016
142
12

Calpain-generated natural protein fragments as short-lived substrates of the N-end rule pathway.
Konstantin I Piatkov, Jang-Hyun Oh, Yuan Liu, Alexander Varshavsky. Proc Natl Acad Sci U S A 2014
61
19

Control of mammalian G protein signaling by N-terminal acetylation and the N-end rule pathway.
Sang-Eun Park, Jeong-Mok Kim, Ok-Hee Seok, Hanna Cho, Brandon Wadas, Seon-Young Kim, Alexander Varshavsky, Cheol-Sang Hwang. Science 2015
95
12

The substrate recognition domains of the N-end rule pathway.
Takafumi Tasaki, Adriana Zakrzewska, Drew D Dudgeon, Yonghua Jiang, John S Lazo, Yong Tae Kwon. J Biol Chem 2009
93
12

Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants.
Norma Masson, Thomas P Keeley, Beatrice Giuntoli, Mark D White, Mikel Lavilla Puerta, Pierdomenico Perata, Richard J Hopkinson, Emily Flashman, Francesco Licausi, Peter J Ratcliffe. Science 2019
86
13

Degradation of DIAP1 by the N-end rule pathway is essential for regulating apoptosis.
Mark Ditzel, Rebecca Wilson, Tencho Tenev, Anna Zachariou, Angela Paul, Emma Deas, Pascal Meier. Nat Cell Biol 2003
200
11

Basic Medical Research Award. The ubiquitin system.
A Hershko, A Ciechanover, A Varshavsky. Nat Med 2000
537
11

The Eukaryotic Proteome Is Shaped by E3 Ubiquitin Ligases Targeting C-Terminal Degrons.
Itay Koren, Richard T Timms, Tomasz Kula, Qikai Xu, Mamie Z Li, Stephen J Elledge. Cell 2018
102
11

Understanding the Pro/N-end rule pathway.
David A Dougan, Alexander Varshavsky. Nat Chem Biol 2018
14
78

Nitric oxide sensing in plants is mediated by proteolytic control of group VII ERF transcription factors.
Daniel J Gibbs, Nurulhikma Md Isa, Mahsa Movahedi, Jorge Lozano-Juste, Guillermina M Mendiondo, Sophie Berckhan, Nora Marín-de la Rosa, Jorge Vicente Conde, Cristina Sousa Correia, Simon P Pearce,[...]. Mol Cell 2014
217
10

Discovery of cellular regulation by protein degradation.
Alexander Varshavsky. J Biol Chem 2008
74
13

Ubiquitin Ligases: Structure, Function, and Regulation.
Ning Zheng, Nitzan Shabek. Annu Rev Biochem 2017
569
10

Structural basis for dual specificity of yeast N-terminal amidase in the N-end rule pathway.
Min Kyung Kim, Sun Joo Oh, Byung-Gil Lee, Hyun Kyu Song. Proc Natl Acad Sci U S A 2016
21
47


C-Terminal End-Directed Protein Elimination by CRL2 Ubiquitin Ligases.
Hsiu-Chuan Lin, Chi-Wei Yeh, Yen-Fu Chen, Ting-Ting Lee, Pei-Yun Hsieh, Domnita V Rusnac, Sung-Ya Lin, Stephen J Elledge, Ning Zheng, Hsueh-Chi S Yen. Mol Cell 2018
67
14

The N-end rule in bacteria.
J W Tobias, T E Shrader, G Rocap, A Varshavsky. Science 1991
422
10

Aminoacyl-transferases and the N-end rule pathway of prokaryotic/eukaryotic specificity in a human pathogen.
Emmanuelle Graciet, Rong-Gui Hu, Konstantin Piatkov, Joon Haeng Rhee, Erich M Schwarz, Alexander Varshavsky. Proc Natl Acad Sci U S A 2006
72
13



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.