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Times Cited: 285
Times Cited
Times Co-cited
Similarity
Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2.
Richard A Morgan, James C Yang, Mio Kitano, Mark E Dudley, Carolyn M Laurencot, Steven A Rosenberg. Mol Ther 2010
Richard A Morgan, James C Yang, Mio Kitano, Mark E Dudley, Carolyn M Laurencot, Steven A Rosenberg. Mol Ther 2010
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Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells.
Christopher C Kloss, Maud Condomines, Marc Cartellieri, Michael Bachmann, Michel Sadelain. Nat Biotechnol 2013
Christopher C Kloss, Maud Condomines, Marc Cartellieri, Michael Bachmann, Michel Sadelain. Nat Biotechnol 2013
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PD-1- and CTLA-4-based inhibitory chimeric antigen receptors (iCARs) divert off-target immunotherapy responses.
Victor D Fedorov, Maria Themeli, Michel Sadelain. Sci Transl Med 2013
Victor D Fedorov, Maria Themeli, Michel Sadelain. Sci Transl Med 2013
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Chimeric antigen receptor T Cells with dissociated signaling domains exhibit focused antitumor activity with reduced potential for toxicity in vivo.
Evripidis Lanitis, Mathilde Poussin, Alex W Klattenhoff, Degang Song, Raphael Sandaltzopoulos, Carl H June, Daniel J Powell. Cancer Immunol Res 2013
Evripidis Lanitis, Mathilde Poussin, Alex W Klattenhoff, Degang Song, Raphael Sandaltzopoulos, Carl H June, Daniel J Powell. Cancer Immunol Res 2013
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Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits.
Kole T Roybal, Levi J Rupp, Leonardo Morsut, Whitney J Walker, Krista A McNally, Jason S Park, Wendell A Lim. Cell 2016
Kole T Roybal, Levi J Rupp, Leonardo Morsut, Whitney J Walker, Krista A McNally, Jason S Park, Wendell A Lim. Cell 2016
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Chimeric antigen receptor T cells for sustained remissions in leukemia.
Shannon L Maude, Noelle Frey, Pamela A Shaw, Richard Aplenc, David M Barrett, Nancy J Bunin, Anne Chew, Vanessa E Gonzalez, Zhaohui Zheng, Simon F Lacey,[...]. N Engl J Med 2014
Shannon L Maude, Noelle Frey, Pamela A Shaw, Richard Aplenc, David M Barrett, Nancy J Bunin, Anne Chew, Vanessa E Gonzalez, Zhaohui Zheng, Simon F Lacey,[...]. N Engl J Med 2014
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Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape.
Meenakshi Hegde, Malini Mukherjee, Zakaria Grada, Antonella Pignata, Daniel Landi, Shoba A Navai, Amanda Wakefield, Kristen Fousek, Kevin Bielamowicz, Kevin K H Chow,[...]. J Clin Invest 2016
Meenakshi Hegde, Malini Mukherjee, Zakaria Grada, Antonella Pignata, Daniel Landi, Shoba A Navai, Amanda Wakefield, Kristen Fousek, Kevin Bielamowicz, Kevin K H Chow,[...]. J Clin Invest 2016
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A Chimeric Switch-Receptor Targeting PD1 Augments the Efficacy of Second-Generation CAR T Cells in Advanced Solid Tumors.
Xiaojun Liu, Raghuveer Ranganathan, Shuguang Jiang, Chongyun Fang, Jing Sun, Soyeon Kim, Kheng Newick, Albert Lo, Carl H June, Yangbing Zhao,[...]. Cancer Res 2016
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Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia.
Shannon L Maude, Theodore W Laetsch, Jochen Buechner, Susana Rives, Michael Boyer, Henrique Bittencourt, Peter Bader, Michael R Verneris, Heather E Stefanski, Gary D Myers,[...]. N Engl J Med 2018
Shannon L Maude, Theodore W Laetsch, Jochen Buechner, Susana Rives, Michael Boyer, Henrique Bittencourt, Peter Bader, Michael R Verneris, Heather E Stefanski, Gary D Myers,[...]. N Engl J Med 2018
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Universal Chimeric Antigen Receptors for Multiplexed and Logical Control of T Cell Responses.
Jang Hwan Cho, James J Collins, Wilson W Wong. Cell 2018
Jang Hwan Cho, James J Collins, Wilson W Wong. Cell 2018
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A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma.
Donald M O'Rourke, MacLean P Nasrallah, Arati Desai, Jan J Melenhorst, Keith Mansfield, Jennifer J D Morrissette, Maria Martinez-Lage, Steven Brem, Eileen Maloney, Angela Shen,[...]. Sci Transl Med 2017
Donald M O'Rourke, MacLean P Nasrallah, Arati Desai, Jan J Melenhorst, Keith Mansfield, Jennifer J D Morrissette, Maria Martinez-Lage, Steven Brem, Eileen Maloney, Angela Shen,[...]. Sci Transl Med 2017
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Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes.
Ignazio Caruana, Barbara Savoldo, Valentina Hoyos, Gerrit Weber, Hao Liu, Eugene S Kim, Michael M Ittmann, Dario Marchetti, Gianpietro Dotti. Nat Med 2015
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Inducible apoptosis as a safety switch for adoptive cell therapy.
Antonio Di Stasi, Siok-Keen Tey, Gianpietro Dotti, Yuriko Fujita, Alana Kennedy-Nasser, Caridad Martinez, Karin Straathof, Enli Liu, April G Durett, Bambi Grilley,[...]. N Engl J Med 2011
Antonio Di Stasi, Siok-Keen Tey, Gianpietro Dotti, Yuriko Fujita, Alana Kennedy-Nasser, Caridad Martinez, Karin Straathof, Enli Liu, April G Durett, Bambi Grilley,[...]. N Engl J Med 2011
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Remote control of therapeutic T cells through a small molecule-gated chimeric receptor.
Chia-Yung Wu, Kole T Roybal, Elias M Puchner, James Onuffer, Wendell A Lim. Science 2015
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Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma.
Sattva S Neelapu, Frederick L Locke, Nancy L Bartlett, Lazaros J Lekakis, David B Miklos, Caron A Jacobson, Ira Braunschweig, Olalekan O Oluwole, Tanya Siddiqi, Yi Lin,[...]. N Engl J Med 2017
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Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors.
Z Eshhar, T Waks, G Gross, D G Schindler. Proc Natl Acad Sci U S A 1993
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Chimeric antigen receptor-modified T cells for acute lymphoid leukemia.
Stephan A Grupp, Michael Kalos, David Barrett, Richard Aplenc, David L Porter, Susan R Rheingold, David T Teachey, Anne Chew, Bernd Hauck, J Fraser Wright,[...]. N Engl J Med 2013
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25
Affinity-Tuned ErbB2 or EGFR Chimeric Antigen Receptor T Cells Exhibit an Increased Therapeutic Index against Tumors in Mice.
Xiaojun Liu, Shuguang Jiang, Chongyun Fang, Shiyu Yang, Devvora Olalere, Edward C Pequignot, Alexandria P Cogdill, Na Li, Melissa Ramones, Brian Granda,[...]. Cancer Res 2015
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Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies.
Marco Ruella, David M Barrett, Saad S Kenderian, Olga Shestova, Ted J Hofmann, Jessica Perazzelli, Michael Klichinsky, Vania Aikawa, Farzana Nazimuddin, Miroslaw Kozlowski,[...]. J Clin Invest 2016
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Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy.
Christine E Brown, Darya Alizadeh, Renate Starr, Lihong Weng, Jamie R Wagner, Araceli Naranjo, Julie R Ostberg, M Suzette Blanchard, Julie Kilpatrick, Jennifer Simpson,[...]. N Engl J Med 2016
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Switch-mediated activation and retargeting of CAR-T cells for B-cell malignancies.
David T Rodgers, Magdalena Mazagova, Eric N Hampton, Yu Cao, Nitya S Ramadoss, Ian R Hardy, Andrew Schulman, Juanjuan Du, Feng Wang, Oded Singer,[...]. Proc Natl Acad Sci U S A 2016
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Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity.
G Gross, T Waks, Z Eshhar. Proc Natl Acad Sci U S A 1989
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CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia.
Renier J Brentjens, Marco L Davila, Isabelle Riviere, Jae Park, Xiuyan Wang, Lindsay G Cowell, Shirley Bartido, Jolanta Stefanski, Clare Taylor, Malgorzata Olszewska,[...]. Sci Transl Med 2013
Renier J Brentjens, Marco L Davila, Isabelle Riviere, Jae Park, Xiuyan Wang, Lindsay G Cowell, Shirley Bartido, Jolanta Stefanski, Clare Taylor, Malgorzata Olszewska,[...]. Sci Transl Med 2013
23
T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial.
Daniel W Lee, James N Kochenderfer, Maryalice Stetler-Stevenson, Yongzhi K Cui, Cindy Delbrook, Steven A Feldman, Terry J Fry, Rimas Orentas, Marianna Sabatino, Nirali N Shah,[...]. Lancet 2015
Daniel W Lee, James N Kochenderfer, Maryalice Stetler-Stevenson, Yongzhi K Cui, Cindy Delbrook, Steven A Feldman, Terry J Fry, Rimas Orentas, Marianna Sabatino, Nirali N Shah,[...]. Lancet 2015
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Augmentation of Antitumor Immunity by Human and Mouse CAR T Cells Secreting IL-18.
Biliang Hu, Jiangtao Ren, Yanping Luo, Brian Keith, Regina M Young, John Scholler, Yangbing Zhao, Carl H June. Cell Rep 2017
Biliang Hu, Jiangtao Ren, Yanping Luo, Brian Keith, Regina M Young, John Scholler, Yangbing Zhao, Carl H June. Cell Rep 2017
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Mesothelin-specific chimeric antigen receptor mRNA-engineered T cells induce anti-tumor activity in solid malignancies.
Gregory L Beatty, Andrew R Haas, Marcela V Maus, Drew A Torigian, Michael C Soulen, Gabriela Plesa, Anne Chew, Yangbing Zhao, Bruce L Levine, Steven M Albelda,[...]. Cancer Immunol Res 2014
Gregory L Beatty, Andrew R Haas, Marcela V Maus, Drew A Torigian, Michael C Soulen, Gabriela Plesa, Anne Chew, Yangbing Zhao, Bruce L Levine, Steven M Albelda,[...]. Cancer Immunol Res 2014
23
CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B cell ALL patients.
Cameron J Turtle, Laïla-Aïcha Hanafi, Carolina Berger, Theodore A Gooley, Sindhu Cherian, Michael Hudecek, Daniel Sommermeyer, Katherine Melville, Barbara Pender, Tanya M Budiarto,[...]. J Clin Invest 2016
Cameron J Turtle, Laïla-Aïcha Hanafi, Carolina Berger, Theodore A Gooley, Sindhu Cherian, Michael Hudecek, Daniel Sommermeyer, Katherine Melville, Barbara Pender, Tanya M Budiarto,[...]. J Clin Invest 2016
22
CAR T Cells Releasing IL-18 Convert to T-Bethigh FoxO1low Effectors that Exhibit Augmented Activity against Advanced Solid Tumors.
Markus Chmielewski, Hinrich Abken. Cell Rep 2017
Markus Chmielewski, Hinrich Abken. Cell Rep 2017
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Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition.
Leonid Cherkassky, Aurore Morello, Jonathan Villena-Vargas, Yang Feng, Dimiter S Dimitrov, David R Jones, Michel Sadelain, Prasad S Adusumilli. J Clin Invest 2016
Leonid Cherkassky, Aurore Morello, Jonathan Villena-Vargas, Yang Feng, Dimiter S Dimitrov, David R Jones, Michel Sadelain, Prasad S Adusumilli. J Clin Invest 2016
22
4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors.
Adrienne H Long, Waleed M Haso, Jack F Shern, Kelsey M Wanhainen, Meera Murgai, Maria Ingaramo, Jillian P Smith, Alec J Walker, M Eric Kohler, Vikas R Venkateshwara,[...]. Nat Med 2015
Adrienne H Long, Waleed M Haso, Jack F Shern, Kelsey M Wanhainen, Meera Murgai, Maria Ingaramo, Jillian P Smith, Alec J Walker, M Eric Kohler, Vikas R Venkateshwara,[...]. Nat Med 2015
22
TanCAR: A Novel Bispecific Chimeric Antigen Receptor for Cancer Immunotherapy.
Zakaria Grada, Meenakshi Hegde, Tiara Byrd, Donald R Shaffer, Alexia Ghazi, Vita S Brawley, Amanda Corder, Kurt Schönfeld, Joachim Koch, Gianpietro Dotti,[...]. Mol Ther Nucleic Acids 2013
Zakaria Grada, Meenakshi Hegde, Tiara Byrd, Donald R Shaffer, Alexia Ghazi, Vita S Brawley, Amanda Corder, Kurt Schönfeld, Joachim Koch, Gianpietro Dotti,[...]. Mol Ther Nucleic Acids 2013
22
Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting.
Shivani Srivastava, Alexander I Salter, Denny Liggitt, Sushma Yechan-Gunja, Megha Sarvothama, Kirsten Cooper, Kimberly S Smythe, Jarrod A Dudakov, Robert H Pierce, Christoph Rader,[...]. Cancer Cell 2019
Shivani Srivastava, Alexander I Salter, Denny Liggitt, Sushma Yechan-Gunja, Megha Sarvothama, Kirsten Cooper, Kimberly S Smythe, Jarrod A Dudakov, Robert H Pierce, Christoph Rader,[...]. Cancer Cell 2019
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Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b.
John A Craddock, An Lu, Adham Bear, Martin Pule, Malcolm K Brenner, Cliona M Rooney, Aaron E Foster. J Immunother 2010
John A Craddock, An Lu, Adham Bear, Martin Pule, Malcolm K Brenner, Cliona M Rooney, Aaron E Foster. J Immunother 2010
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Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection.
Justin Eyquem, Jorge Mansilla-Soto, Theodoros Giavridis, Sjoukje J C van der Stegen, Mohamad Hamieh, Kristen M Cunanan, Ashlesha Odak, Mithat Gönen, Michel Sadelain. Nature 2017
Justin Eyquem, Jorge Mansilla-Soto, Theodoros Giavridis, Sjoukje J C van der Stegen, Mohamad Hamieh, Kristen M Cunanan, Ashlesha Odak, Mithat Gönen, Michel Sadelain. Nature 2017
21
Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia.
Marco L Davila, Isabelle Riviere, Xiuyan Wang, Shirley Bartido, Jae Park, Kevin Curran, Stephen S Chung, Jolanta Stefanski, Oriana Borquez-Ojeda, Malgorzata Olszewska,[...]. Sci Transl Med 2014
Marco L Davila, Isabelle Riviere, Xiuyan Wang, Shirley Bartido, Jae Park, Kevin Curran, Stephen S Chung, Jolanta Stefanski, Oriana Borquez-Ojeda, Malgorzata Olszewska,[...]. Sci Transl Med 2014
20
Treatment of metastatic renal cell carcinoma with CAIX CAR-engineered T cells: clinical evaluation and management of on-target toxicity.
Cor Hj Lamers, Stefan Sleijfer, Sabine van Steenbergen, Pascal van Elzakker, Brigitte van Krimpen, Corrien Groot, Arnold Vulto, Michael den Bakker, Egbert Oosterwijk, Reno Debets,[...]. Mol Ther 2013
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Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning.
Hollie J Pegram, James C Lee, Erik G Hayman, Gavin H Imperato, Thomas F Tedder, Michel Sadelain, Renier J Brentjens. Blood 2012
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Expression of a functional CCR2 receptor enhances tumor localization and tumor eradication by retargeted human T cells expressing a mesothelin-specific chimeric antibody receptor.
Edmund K Moon, Carmine Carpenito, Jing Sun, Liang-Chuan S Wang, Veena Kapoor, Jarrod Predina, Daniel J Powell, James L Riley, Carl H June, Steven M Albelda. Clin Cancer Res 2011
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Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors.
Kole T Roybal, Jasper Z Williams, Leonardo Morsut, Levi J Rupp, Isabel Kolinko, Joseph H Choe, Whitney J Walker, Krista A McNally, Wendell A Lim. Cell 2016
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Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation.
Sonia Guedan, Avery D Posey, Carolyn Shaw, Anna Wing, Tong Da, Prachi R Patel, Shannon E McGettigan, Victoria Casado-Medrano, Omkar U Kawalekar, Mireia Uribe-Herranz,[...]. JCI Insight 2018
Sonia Guedan, Avery D Posey, Carolyn Shaw, Anna Wing, Tong Da, Prachi R Patel, Shannon E McGettigan, Victoria Casado-Medrano, Omkar U Kawalekar, Mireia Uribe-Herranz,[...]. JCI Insight 2018
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Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo.
Sarwish Rafiq, Oladapo O Yeku, Hollie J Jackson, Terence J Purdon, Dayenne G van Leeuwen, Dylan J Drakes, Mei Song, Matthew M Miele, Zhuoning Li, Pei Wang,[...]. Nat Biotechnol 2018
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Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia.
Jae H Park, Isabelle Rivière, Mithat Gonen, Xiuyan Wang, Brigitte Sénéchal, Kevin J Curran, Craig Sauter, Yongzeng Wang, Bianca Santomasso, Elena Mead,[...]. N Engl J Med 2018
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Dominant-Negative TGF-β Receptor Enhances PSMA-Targeted Human CAR T Cell Proliferation And Augments Prostate Cancer Eradication.
Christopher C Kloss, Jihyun Lee, Aaron Zhang, Fang Chen, Jan Joseph Melenhorst, Simon F Lacey, Marcela V Maus, Joseph A Fraietta, Yangbing Zhao, Carl H June. Mol Ther 2018
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T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model.
Antonio Di Stasi, Biagio De Angelis, Cliona M Rooney, Lan Zhang, Aruna Mahendravada, Aaron E Foster, Helen E Heslop, Malcolm K Brenner, Gianpietro Dotti, Barbara Savoldo. Blood 2009
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A versatile system for rapid multiplex genome-edited CAR T cell generation.
Jiangtao Ren, Xuhua Zhang, Xiaojun Liu, Chongyun Fang, Shuguang Jiang, Carl H June, Yangbing Zhao. Oncotarget 2017
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IL-12 secreting tumor-targeted chimeric antigen receptor T cells eradicate ovarian tumors in vivo.
Mythili Koneru, Terence J Purdon, David Spriggs, Susmith Koneru, Renier J Brentjens. Oncoimmunology 2015
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Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia.
David L Porter, Bruce L Levine, Michael Kalos, Adam Bagg, Carl H June. N Engl J Med 2011
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TRUCKs: the fourth generation of CARs.
Markus Chmielewski, Hinrich Abken. Expert Opin Biol Ther 2015
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T Cells Expressing CD19/CD20 Bispecific Chimeric Antigen Receptors Prevent Antigen Escape by Malignant B Cells.
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Switching CAR T cells on and off: a novel modular platform for retargeting of T cells to AML blasts.
M Cartellieri, A Feldmann, S Koristka, C Arndt, S Loff, A Ehninger, M von Bonin, E P Bejestani, G Ehninger, M P Bachmann. Blood Cancer J 2016
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.