Miao Yu, Gary C Hon, Keith E Szulwach, Chun-Xiao Song, Liang Zhang, Audrey Kim, Xuekun Li, Qing Dai, Yin Shen, Beomseok Park, Jung-Hyun Min, Peng Jin, Bing Ren, Chuan He. Cell 2012
Times Cited: 709
Times Cited: 709
Times Cited
Times Co-cited
Similarity
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.
Mamta Tahiliani, Kian Peng Koh, Yinghua Shen, William A Pastor, Hozefa Bandukwala, Yevgeny Brudno, Suneet Agarwal, Lakshminarayan M Iyer, David R Liu, L Aravind,[...]. Science 2009
Mamta Tahiliani, Kian Peng Koh, Yinghua Shen, William A Pastor, Hozefa Bandukwala, Yevgeny Brudno, Suneet Agarwal, Lakshminarayan M Iyer, David R Liu, L Aravind,[...]. Science 2009
49
Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution.
Michael J Booth, Miguel R Branco, Gabriella Ficz, David Oxley, Felix Krueger, Wolf Reik, Shankar Balasubramanian. Science 2012
Michael J Booth, Miguel R Branco, Gabriella Ficz, David Oxley, Felix Krueger, Wolf Reik, Shankar Balasubramanian. Science 2012
44
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.
Shinsuke Ito, Li Shen, Qing Dai, Susan C Wu, Leonard B Collins, James A Swenberg, Chuan He, Yi Zhang. Science 2011
Shinsuke Ito, Li Shen, Qing Dai, Susan C Wu, Leonard B Collins, James A Swenberg, Chuan He, Yi Zhang. Science 2011
40
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA.
Yu-Fei He, Bin-Zhong Li, Zheng Li, Peng Liu, Yang Wang, Qingyu Tang, Jianping Ding, Yingying Jia, Zhangcheng Chen, Lin Li,[...]. Science 2011
Yu-Fei He, Bin-Zhong Li, Zheng Li, Peng Liu, Yang Wang, Qingyu Tang, Jianping Ding, Yingying Jia, Zhangcheng Chen, Lin Li,[...]. Science 2011
31
Bisulfite-free direct detection of 5-methylcytosine and 5-hydroxymethylcytosine at base resolution.
Yibin Liu, Paulina Siejka-Zielińska, Gergana Velikova, Ying Bi, Fang Yuan, Marketa Tomkova, Chunsen Bai, Lei Chen, Benjamin Schuster-Böckler, Chun-Xiao Song. Nat Biotechnol 2019
Yibin Liu, Paulina Siejka-Zielińska, Gergana Velikova, Ying Bi, Fang Yuan, Marketa Tomkova, Chunsen Bai, Lei Chen, Benjamin Schuster-Böckler, Chun-Xiao Song. Nat Biotechnol 2019
28
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.
Chun-Xiao Song, Keith E Szulwach, Ye Fu, Qing Dai, Chengqi Yi, Xuekun Li, Yujing Li, Chih-Hsin Chen, Wen Zhang, Xing Jian,[...]. Nat Biotechnol 2011
Chun-Xiao Song, Keith E Szulwach, Ye Fu, Qing Dai, Chengqi Yi, Xuekun Li, Yujing Li, Chih-Hsin Chen, Wen Zhang, Xing Jian,[...]. Nat Biotechnol 2011
28
Nondestructive, base-resolution sequencing of 5-hydroxymethylcytosine using a DNA deaminase.
Emily K Schutsky, Jamie E DeNizio, Peng Hu, Monica Yun Liu, Christopher S Nabel, Emily B Fabyanic, Young Hwang, Frederic D Bushman, Hao Wu, Rahul M Kohli. Nat Biotechnol 2018
Emily K Schutsky, Jamie E DeNizio, Peng Hu, Monica Yun Liu, Christopher S Nabel, Emily B Fabyanic, Young Hwang, Frederic D Bushman, Hao Wu, Rahul M Kohli. Nat Biotechnol 2018
26
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain.
Skirmantas Kriaucionis, Nathaniel Heintz. Science 2009
Skirmantas Kriaucionis, Nathaniel Heintz. Science 2009
24
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification.
Shinsuke Ito, Ana C D'Alessio, Olena V Taranova, Kwonho Hong, Lawrence C Sowers, Yi Zhang. Nature 2010
Shinsuke Ito, Ana C D'Alessio, Olena V Taranova, Kwonho Hong, Lawrence C Sowers, Yi Zhang. Nature 2010
20
DNA methylation: roles in mammalian development.
Zachary D Smith, Alexander Meissner. Nat Rev Genet 2013
Zachary D Smith, Alexander Meissner. Nat Rev Genet 2013
18
TET-mediated active DNA demethylation: mechanism, function and beyond.
Xiaoji Wu, Yi Zhang. Nat Rev Genet 2017
Xiaoji Wu, Yi Zhang. Nat Rev Genet 2017
18
Human DNA methylomes at base resolution show widespread epigenomic differences.
Ryan Lister, Mattia Pelizzola, Robert H Dowen, R David Hawkins, Gary Hon, Julian Tonti-Filippini, Joseph R Nery, Leonard Lee, Zhen Ye, Que-Minh Ngo,[...]. Nature 2009
Ryan Lister, Mattia Pelizzola, Robert H Dowen, R David Hawkins, Gary Hon, Julian Tonti-Filippini, Joseph R Nery, Leonard Lee, Zhen Ye, Que-Minh Ngo,[...]. Nature 2009
17
The diverse roles of DNA methylation in mammalian development and disease.
Maxim V C Greenberg, Deborah Bourc'his. Nat Rev Mol Cell Biol 2019
Maxim V C Greenberg, Deborah Bourc'his. Nat Rev Mol Cell Biol 2019
17
Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation.
Gabriella Ficz, Miguel R Branco, Stefanie Seisenberger, Fátima Santos, Felix Krueger, Timothy A Hore, C Joana Marques, Simon Andrews, Wolf Reik. Nature 2011
Gabriella Ficz, Miguel R Branco, Stefanie Seisenberger, Fátima Santos, Felix Krueger, Timothy A Hore, C Joana Marques, Simon Andrews, Wolf Reik. Nature 2011
16
5-Hydroxymethylcytosine is a predominantly stable DNA modification.
Martin Bachman, Santiago Uribe-Lewis, Xiaoping Yang, Michael Williams, Adele Murrell, Shankar Balasubramanian. Nat Chem 2014
Martin Bachman, Santiago Uribe-Lewis, Xiaoping Yang, Michael Williams, Adele Murrell, Shankar Balasubramanian. Nat Chem 2014
16
Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives.
Cornelia G Spruijt, Felix Gnerlich, Arne H Smits, Toni Pfaffeneder, Pascal W T C Jansen, Christina Bauer, Martin Münzel, Mirko Wagner, Markus Müller, Fariha Khan,[...]. Cell 2013
Cornelia G Spruijt, Felix Gnerlich, Arne H Smits, Toni Pfaffeneder, Pascal W T C Jansen, Christina Bauer, Martin Münzel, Mirko Wagner, Markus Müller, Fariha Khan,[...]. Cell 2013
16
Bisulfite-Free, Nanoscale Analysis of 5-Hydroxymethylcytosine at Single Base Resolution.
Hu Zeng, Bo He, Bo Xia, Dongsheng Bai, Xingyu Lu, Jiabin Cai, Lei Chen, Ankun Zhou, Chenxu Zhu, Haowei Meng,[...]. J Am Chem Soc 2018
Hu Zeng, Bo He, Bo Xia, Dongsheng Bai, Xingyu Lu, Jiabin Cai, Lei Chen, Ankun Zhou, Chenxu Zhu, Haowei Meng,[...]. J Am Chem Soc 2018
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Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells.
William A Pastor, Utz J Pape, Yun Huang, Hope R Henderson, Ryan Lister, Myunggon Ko, Erin M McLoughlin, Yevgeny Brudno, Sahasransu Mahapatra, Philipp Kapranov,[...]. Nature 2011
William A Pastor, Utz J Pape, Yun Huang, Hope R Henderson, Ryan Lister, Myunggon Ko, Erin M McLoughlin, Yevgeny Brudno, Sahasransu Mahapatra, Philipp Kapranov,[...]. Nature 2011
14
Oxidative bisulfite sequencing of 5-methylcytosine and 5-hydroxymethylcytosine.
Michael J Booth, Tobias W B Ost, Dario Beraldi, Neil M Bell, Miguel R Branco, Wolf Reik, Shankar Balasubramanian. Nat Protoc 2013
Michael J Booth, Tobias W B Ost, Dario Beraldi, Neil M Bell, Miguel R Branco, Wolf Reik, Shankar Balasubramanian. Nat Protoc 2013
13
Degradation of DNA by bisulfite treatment.
Kazuo Tanaka, Akimitsu Okamoto. Bioorg Med Chem Lett 2007
Kazuo Tanaka, Akimitsu Okamoto. Bioorg Med Chem Lett 2007
13
MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system.
Marian Mellén, Pinar Ayata, Scott Dewell, Skirmantas Kriaucionis, Nathaniel Heintz. Cell 2012
Marian Mellén, Pinar Ayata, Scott Dewell, Skirmantas Kriaucionis, Nathaniel Heintz. Cell 2012
13
A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands.
M Frommer, L E McDonald, D S Millar, C M Collis, F Watt, G W Grigg, P L Molloy, C L Paul. Proc Natl Acad Sci U S A 1992
M Frommer, L E McDonald, D S Millar, C M Collis, F Watt, G W Grigg, P L Molloy, C L Paul. Proc Natl Acad Sci U S A 1992
13
5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging.
Keith E Szulwach, Xuekun Li, Yujing Li, Chun-Xiao Song, Hao Wu, Qing Dai, Hasan Irier, Anup K Upadhyay, Marla Gearing, Allan I Levey,[...]. Nat Neurosci 2011
Keith E Szulwach, Xuekun Li, Yujing Li, Chun-Xiao Song, Hao Wu, Qing Dai, Hasan Irier, Anup K Upadhyay, Marla Gearing, Allan I Levey,[...]. Nat Neurosci 2011
12
5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers.
Wenshuai Li, Xu Zhang, Xingyu Lu, Lei You, Yanqun Song, Zhongguang Luo, Jun Zhang, Ji Nie, Wanwei Zheng, Diannan Xu,[...]. Cell Res 2017
Wenshuai Li, Xu Zhang, Xingyu Lu, Lei You, Yanqun Song, Zhongguang Luo, Jun Zhang, Ji Nie, Wanwei Zheng, Diannan Xu,[...]. Cell Res 2017
12
5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages.
Chun-Xiao Song, Senlin Yin, Li Ma, Amanda Wheeler, Yu Chen, Yan Zhang, Bin Liu, Junjie Xiong, Weihan Zhang, Jiankun Hu,[...]. Cell Res 2017
Chun-Xiao Song, Senlin Yin, Li Ma, Amanda Wheeler, Yu Chen, Yan Zhang, Bin Liu, Junjie Xiong, Weihan Zhang, Jiankun Hu,[...]. Cell Res 2017
12
12
Bisulfite-free, base-resolution analysis of 5-formylcytosine at the genome scale.
Bo Xia, Dali Han, Xingyu Lu, Zhaozhu Sun, Ankun Zhou, Qiangzong Yin, Hu Zeng, Menghao Liu, Xiang Jiang, Wei Xie,[...]. Nat Methods 2015
Bo Xia, Dali Han, Xingyu Lu, Zhaozhu Sun, Ankun Zhou, Qiangzong Yin, Hu Zeng, Menghao Liu, Xiang Jiang, Wei Xie,[...]. Nat Methods 2015
12
Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites.
Atanu Maiti, Alexander C Drohat. J Biol Chem 2011
Atanu Maiti, Alexander C Drohat. J Biol Chem 2011
11
5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells.
Hume Stroud, Suhua Feng, Shannon Morey Kinney, Sriharsa Pradhan, Steven E Jacobsen. Genome Biol 2011
Hume Stroud, Suhua Feng, Shannon Morey Kinney, Sriharsa Pradhan, Steven E Jacobsen. Genome Biol 2011
11
Global epigenomic reconfiguration during mammalian brain development.
Ryan Lister, Eran A Mukamel, Joseph R Nery, Mark Urich, Clare A Puddifoot, Nicholas D Johnson, Jacinta Lucero, Yun Huang, Andrew J Dwork, Matthew D Schultz,[...]. Science 2013
Ryan Lister, Eran A Mukamel, Joseph R Nery, Mark Urich, Clare A Puddifoot, Nicholas D Johnson, Jacinta Lucero, Yun Huang, Andrew J Dwork, Matthew D Schultz,[...]. Science 2013
11
Role of TET enzymes in DNA methylation, development, and cancer.
Kasper Dindler Rasmussen, Kristian Helin. Genes Dev 2016
Kasper Dindler Rasmussen, Kristian Helin. Genes Dev 2016
11
Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications.
Felix Krueger, Simon R Andrews. Bioinformatics 2011
Felix Krueger, Simon R Andrews. Bioinformatics 2011
11
The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing.
Yun Huang, William A Pastor, Yinghua Shen, Mamta Tahiliani, David R Liu, Anjana Rao. PLoS One 2010
Yun Huang, William A Pastor, Yinghua Shen, Mamta Tahiliani, David R Liu, Anjana Rao. PLoS One 2010
11
Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming.
Chun-Xiao Song, Keith E Szulwach, Qing Dai, Ye Fu, Shi-Qing Mao, Li Lin, Craig Street, Yujing Li, Mickael Poidevin, Hao Wu,[...]. Cell 2013
Chun-Xiao Song, Keith E Szulwach, Qing Dai, Ye Fu, Shi-Qing Mao, Li Lin, Craig Street, Yujing Li, Mickael Poidevin, Hao Wu,[...]. Cell 2013
10
Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells.
Yufei Xu, Feizhen Wu, Li Tan, Lingchun Kong, Lijun Xiong, Jie Deng, Andrew J Barbera, Lijuan Zheng, Haikuo Zhang, Stephen Huang,[...]. Mol Cell 2011
Yufei Xu, Feizhen Wu, Li Tan, Lingchun Kong, Lijun Xiong, Jie Deng, Andrew J Barbera, Lijuan Zheng, Haikuo Zhang, Stephen Huang,[...]. Mol Cell 2011
10
Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine.
Seung-Gi Jin, Swati Kadam, Gerd P Pfeifer. Nucleic Acids Res 2010
Seung-Gi Jin, Swati Kadam, Gerd P Pfeifer. Nucleic Acids Res 2010
10
Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates.
Daniel Globisch, Martin Münzel, Markus Müller, Stylianos Michalakis, Mirko Wagner, Susanne Koch, Tobias Brückl, Martin Biel, Thomas Carell. PLoS One 2010
Daniel Globisch, Martin Münzel, Markus Müller, Stylianos Michalakis, Mirko Wagner, Susanne Koch, Tobias Brückl, Martin Biel, Thomas Carell. PLoS One 2010
10
Crystal structure of TET2-DNA complex: insight into TET-mediated 5mC oxidation.
Lulu Hu, Ze Li, Jingdong Cheng, Qinhui Rao, Wei Gong, Mengjie Liu, Yujiang Geno Shi, Jiayu Zhu, Ping Wang, Yanhui Xu. Cell 2013
Lulu Hu, Ze Li, Jingdong Cheng, Qinhui Rao, Wei Gong, Mengjie Liu, Yujiang Geno Shi, Jiayu Zhu, Ping Wang, Yanhui Xu. Cell 2013
10
Integrative genomics viewer.
James T Robinson, Helga Thorvaldsdóttir, Wendy Winckler, Mitchell Guttman, Eric S Lander, Gad Getz, Jill P Mesirov. Nat Biotechnol 2011
James T Robinson, Helga Thorvaldsdóttir, Wendy Winckler, Mitchell Guttman, Eric S Lander, Gad Getz, Jill P Mesirov. Nat Biotechnol 2011
9
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma.
Christine Guo Lian, Yufei Xu, Craig Ceol, Feizhen Wu, Allison Larson, Karen Dresser, Wenqi Xu, Li Tan, Yeguang Hu, Qian Zhan,[...]. Cell 2012
Christine Guo Lian, Yufei Xu, Craig Ceol, Feizhen Wu, Allison Larson, Karen Dresser, Wenqi Xu, Li Tan, Yeguang Hu, Qian Zhan,[...]. Cell 2012
9
9
The Sequence Alignment/Map format and SAMtools.
Heng Li, Bob Handsaker, Alec Wysoker, Tim Fennell, Jue Ruan, Nils Homer, Gabor Marth, Goncalo Abecasis, Richard Durbin. Bioinformatics 2009
Heng Li, Bob Handsaker, Alec Wysoker, Tim Fennell, Jue Ruan, Nils Homer, Gabor Marth, Goncalo Abecasis, Richard Durbin. Bioinformatics 2009
9
5mC oxidation by Tet2 modulates enhancer activity and timing of transcriptome reprogramming during differentiation.
Gary C Hon, Chun-Xiao Song, Tingting Du, Fulai Jin, Siddarth Selvaraj, Ah Young Lee, Chia-An Yen, Zhen Ye, Shi-Qing Mao, Bang-An Wang,[...]. Mol Cell 2014
Gary C Hon, Chun-Xiao Song, Tingting Du, Fulai Jin, Siddarth Selvaraj, Ah Young Lee, Chia-An Yen, Zhen Ye, Shi-Qing Mao, Bang-An Wang,[...]. Mol Cell 2014
9
Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics.
Li Shen, Hao Wu, Dinh Diep, Shinpei Yamaguchi, Ana C D'Alessio, Ho-Lim Fung, Kun Zhang, Yi Zhang. Cell 2013
Li Shen, Hao Wu, Dinh Diep, Shinpei Yamaguchi, Ana C D'Alessio, Ho-Lim Fung, Kun Zhang, Yi Zhang. Cell 2013
9
TETonic shift: biological roles of TET proteins in DNA demethylation and transcription.
William A Pastor, L Aravind, Anjana Rao. Nat Rev Mol Cell Biol 2013
William A Pastor, L Aravind, Anjana Rao. Nat Rev Mol Cell Biol 2013
9
Detecting DNA cytosine methylation using nanopore sequencing.
Jared T Simpson, Rachael E Workman, P C Zuzarte, Matei David, L J Dursi, Winston Timp. Nat Methods 2017
Jared T Simpson, Rachael E Workman, P C Zuzarte, Matei David, L J Dursi, Winston Timp. Nat Methods 2017
8
Direct detection of DNA methylation during single-molecule, real-time sequencing.
Benjamin A Flusberg, Dale R Webster, Jessica H Lee, Kevin J Travers, Eric C Olivares, Tyson A Clark, Jonas Korlach, Stephen W Turner. Nat Methods 2010
Benjamin A Flusberg, Dale R Webster, Jessica H Lee, Kevin J Travers, Eric C Olivares, Tyson A Clark, Jonas Korlach, Stephen W Turner. Nat Methods 2010
8
Sensitive and simultaneous determination of 5-methylcytosine and its oxidation products in genomic DNA by chemical derivatization coupled with liquid chromatography-tandem mass spectrometry analysis.
Yang Tang, Shu-Jian Zheng, Chu-Bo Qi, Yu-Qi Feng, Bi-Feng Yuan. Anal Chem 2015
Yang Tang, Shu-Jian Zheng, Chu-Bo Qi, Yu-Qi Feng, Bi-Feng Yuan. Anal Chem 2015
9
The discovery of 5-formylcytosine in embryonic stem cell DNA.
Toni Pfaffeneder, Benjamin Hackner, Matthias Truss, Martin Münzel, Markus Müller, Christian A Deiml, Christian Hagemeier, Thomas Carell. Angew Chem Int Ed Engl 2011
Toni Pfaffeneder, Benjamin Hackner, Matthias Truss, Martin Münzel, Markus Müller, Christian A Deiml, Christian Hagemeier, Thomas Carell. Angew Chem Int Ed Engl 2011
8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.