LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins.
Brian A Sosa, Andrea Rothballer, Ulrike Kutay, Thomas U Schwartz. Cell 2012
Times Cited: 251
Times Cited: 251
Times Cited
Times Co-cited
Similarity
Coupling of the nucleus and cytoplasm: role of the LINC complex.
Melissa Crisp, Qian Liu, Kyle Roux, J B Rattner, Catherine Shanahan, Brian Burke, Phillip D Stahl, Didier Hodzic. J Cell Biol 2006
Melissa Crisp, Qian Liu, Kyle Roux, J B Rattner, Catherine Shanahan, Brian Burke, Phillip D Stahl, Didier Hodzic. J Cell Biol 2006
67
The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.
V C Padmakumar, Thorsten Libotte, Wenshu Lu, Hafida Zaim, Sabu Abraham, Angelika A Noegel, Josef Gotzmann, Roland Foisner, Iakowos Karakesisoglou. J Cell Sci 2005
V C Padmakumar, Thorsten Libotte, Wenshu Lu, Hafida Zaim, Sabu Abraham, Angelika A Noegel, Josef Gotzmann, Roland Foisner, Iakowos Karakesisoglou. J Cell Sci 2005
29
SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.
Farhana Haque, David J Lloyd, Dawn T Smallwood, Carolyn L Dent, Catherine M Shanahan, Andrew M Fry, Richard C Trembath, Sue Shackleton. Mol Cell Biol 2006
Farhana Haque, David J Lloyd, Dawn T Smallwood, Carolyn L Dent, Catherine M Shanahan, Andrew M Fry, Richard C Trembath, Sue Shackleton. Mol Cell Biol 2006
28
Interactions between nuclei and the cytoskeleton are mediated by SUN-KASH nuclear-envelope bridges.
Daniel A Starr, Heidi N Fridolfsson. Annu Rev Cell Dev Biol 2010
Daniel A Starr, Heidi N Fridolfsson. Annu Rev Cell Dev Biol 2010
28
Structure of Sad1-UNC84 homology (SUN) domain defines features of molecular bridge in nuclear envelope.
Zhaocai Zhou, Xiulian Du, Zheng Cai, Xiaomin Song, Hongtao Zhang, Takako Mizuno, Emi Suzuki, Marla Rosanne Yee, Alan Berezov, Ramachandran Murali,[...]. J Biol Chem 2012
Zhaocai Zhou, Xiulian Du, Zheng Cai, Xiaomin Song, Hongtao Zhang, Takako Mizuno, Emi Suzuki, Marla Rosanne Yee, Alan Berezov, Ramachandran Murali,[...]. J Biol Chem 2012
27
SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.
Xiaochang Zhang, Kai Lei, Xiaobing Yuan, Xiaohui Wu, Yuan Zhuang, Tian Xu, Rener Xu, Min Han. Neuron 2009
Xiaochang Zhang, Kai Lei, Xiaobing Yuan, Xiaohui Wu, Yuan Zhuang, Tian Xu, Rener Xu, Min Han. Neuron 2009
26
Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes.
Farhana Haque, Daniela Mazzeo, Jennifer T Patel, Dawn T Smallwood, Juliet A Ellis, Catherine M Shanahan, Sue Shackleton. J Biol Chem 2010
Farhana Haque, Daniela Mazzeo, Jennifer T Patel, Dawn T Smallwood, Juliet A Ellis, Catherine M Shanahan, Sue Shackleton. J Biol Chem 2010
26
The interaction between nesprins and sun proteins at the nuclear envelope is critical for force transmission between the nucleus and cytoskeleton.
Maria L Lombardi, Diana E Jaalouk, Catherine M Shanahan, Brian Burke, Kyle J Roux, Jan Lammerding. J Biol Chem 2011
Maria L Lombardi, Diana E Jaalouk, Catherine M Shanahan, Brian Burke, Kyle J Roux, Jan Lammerding. J Biol Chem 2011
24
SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice.
Kai Lei, Xiaochang Zhang, Xu Ding, Xue Guo, Muyun Chen, Binggen Zhu, Tian Xu, Yuan Zhuang, Rener Xu, Min Han. Proc Natl Acad Sci U S A 2009
Kai Lei, Xiaochang Zhang, Xu Ding, Xue Guo, Muyun Chen, Binggen Zhu, Tian Xu, Yuan Zhuang, Rener Xu, Min Han. Proc Natl Acad Sci U S A 2009
24
A mammalian KASH domain protein coupling meiotic chromosomes to the cytoskeleton.
Henning F Horn, Dae In Kim, Graham D Wright, Esther Sook Miin Wong, Colin L Stewart, Brian Burke, Kyle J Roux. J Cell Biol 2013
Henning F Horn, Dae In Kim, Graham D Wright, Esther Sook Miin Wong, Colin L Stewart, Brian Burke, Kyle J Roux. J Cell Biol 2013
23
22
Linear arrays of nuclear envelope proteins harness retrograde actin flow for nuclear movement.
G W Gant Luxton, Edgar R Gomes, Eric S Folker, Erin Vintinner, Gregg G Gundersen. Science 2010
G W Gant Luxton, Edgar R Gomes, Eric S Folker, Erin Vintinner, Gregg G Gundersen. Science 2010
22
Nesprin-3, a novel outer nuclear membrane protein, associates with the cytoskeletal linker protein plectin.
Kevin Wilhelmsen, Sandy H M Litjens, Ingrid Kuikman, Ntambua Tshimbalanga, Hans Janssen, Iman van den Bout, Karine Raymond, Arnoud Sonnenberg. J Cell Biol 2005
Kevin Wilhelmsen, Sandy H M Litjens, Ingrid Kuikman, Ntambua Tshimbalanga, Hans Janssen, Iman van den Bout, Karine Raymond, Arnoud Sonnenberg. J Cell Biol 2005
22
Coiled-Coil Domains of SUN Proteins as Intrinsic Dynamic Regulators.
Si Nie, Huimin Ke, Feng Gao, Jinqi Ren, Mingzhu Wang, Lin Huo, Weimin Gong, Wei Feng. Structure 2016
Si Nie, Huimin Ke, Feng Gao, Jinqi Ren, Mingzhu Wang, Lin Huo, Weimin Gong, Wei Feng. Structure 2016
70
Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization.
Kyle J Roux, Melissa L Crisp, Qian Liu, Daein Kim, Serguei Kozlov, Colin L Stewart, Brian Burke. Proc Natl Acad Sci U S A 2009
Kyle J Roux, Melissa L Crisp, Qian Liu, Daein Kim, Serguei Kozlov, Colin L Stewart, Brian Burke. Proc Natl Acad Sci U S A 2009
20
SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice.
Xu Ding, Rener Xu, Juehua Yu, Tian Xu, Yuan Zhuang, Min Han. Dev Cell 2007
Xu Ding, Rener Xu, Juehua Yu, Tian Xu, Yuan Zhuang, Min Han. Dev Cell 2007
20
A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis.
Akihiro Morimoto, Hiroki Shibuya, Xiaoqiang Zhu, Jihye Kim, Kei-ichiro Ishiguro, Min Han, Yoshinori Watanabe. J Cell Biol 2012
Akihiro Morimoto, Hiroki Shibuya, Xiaoqiang Zhu, Jihye Kim, Kei-ichiro Ishiguro, Min Han, Yoshinori Watanabe. J Cell Biol 2012
20
Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.
Qiuping Zhang, Cornelia Bethmann, Nathalie F Worth, John D Davies, Christina Wasner, Anja Feuer, Cassandra D Ragnauth, Qijian Yi, Jason A Mellad, Derek T Warren,[...]. Hum Mol Genet 2007
Qiuping Zhang, Cornelia Bethmann, Nathalie F Worth, John D Davies, Christina Wasner, Anja Feuer, Cassandra D Ragnauth, Qijian Yi, Jason A Mellad, Derek T Warren,[...]. Hum Mol Genet 2007
19
Structural insights into SUN-KASH complexes across the nuclear envelope.
Wenjia Wang, Zhubing Shi, Shi Jiao, Cuicui Chen, Huizhen Wang, Guoguang Liu, Qiang Wang, Yun Zhao, Mark I Greene, Zhaocai Zhou. Cell Res 2012
Wenjia Wang, Zhubing Shi, Shi Jiao, Cuicui Chen, Huizhen Wang, Guoguang Liu, Qiang Wang, Yun Zhao, Mark I Greene, Zhaocai Zhou. Cell Res 2012
26
Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation.
Joe Swift, Irena L Ivanovska, Amnon Buxboim, Takamasa Harada, P C Dave P Dingal, Joel Pinter, J David Pajerowski, Kyle R Spinler, Jae-Won Shin, Manorama Tewari,[...]. Science 2013
Joe Swift, Irena L Ivanovska, Amnon Buxboim, Takamasa Harada, P C Dave P Dingal, Joel Pinter, J David Pajerowski, Kyle R Spinler, Jae-Won Shin, Manorama Tewari,[...]. Science 2013
18
Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus.
Christophe Guilluy, Lukas D Osborne, Laurianne Van Landeghem, Lisa Sharek, Richard Superfine, Rafael Garcia-Mata, Keith Burridge. Nat Cell Biol 2014
Christophe Guilluy, Lukas D Osborne, Laurianne Van Landeghem, Lisa Sharek, Richard Superfine, Rafael Garcia-Mata, Keith Burridge. Nat Cell Biol 2014
18
Accessorizing and anchoring the LINC complex for multifunctionality.
Wakam Chang, Howard J Worman, Gregg G Gundersen. J Cell Biol 2015
Wakam Chang, Howard J Worman, Gregg G Gundersen. J Cell Biol 2015
17
Structural insights into LINC complexes.
Brian A Sosa, Ulrike Kutay, Thomas U Schwartz. Curr Opin Struct Biol 2013
Brian A Sosa, Ulrike Kutay, Thomas U Schwartz. Curr Opin Struct Biol 2013
19
Lamin A/C and emerin regulate MKL1-SRF activity by modulating actin dynamics.
Chin Yee Ho, Diana E Jaalouk, Maria K Vartiainen, Jan Lammerding. Nature 2013
Chin Yee Ho, Diana E Jaalouk, Maria K Vartiainen, Jan Lammerding. Nature 2013
16
The LINC complex is essential for hearing.
Henning F Horn, Zippora Brownstein, Danielle R Lenz, Shaked Shivatzki, Amiel A Dror, Orit Dagan-Rosenfeld, Lilach M Friedman, Kyle J Roux, Serguei Kozlov, Kuan-Teh Jeang,[...]. J Clin Invest 2013
Henning F Horn, Zippora Brownstein, Danielle R Lenz, Shaked Shivatzki, Amiel A Dror, Orit Dagan-Rosenfeld, Lilach M Friedman, Kyle J Roux, Serguei Kozlov, Kuan-Teh Jeang,[...]. J Clin Invest 2013
16
Muscular dystrophy-associated SUN1 and SUN2 variants disrupt nuclear-cytoskeletal connections and myonuclear organization.
Peter Meinke, Elisabetta Mattioli, Farhana Haque, Susumu Antoku, Marta Columbaro, Kees R Straatman, Howard J Worman, Gregg G Gundersen, Giovanna Lattanzi, Manfred Wehnert,[...]. PLoS Genet 2014
Peter Meinke, Elisabetta Mattioli, Farhana Haque, Susumu Antoku, Marta Columbaro, Kees R Straatman, Howard J Worman, Gregg G Gundersen, Giovanna Lattanzi, Manfred Wehnert,[...]. PLoS Genet 2014
16
Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.
Q Zhang, J N Skepper, F Yang, J D Davies, L Hegyi, R G Roberts, P L Weissberg, J A Ellis, C M Shanahan. J Cell Sci 2001
Q Zhang, J N Skepper, F Yang, J D Davies, L Hegyi, R G Roberts, P L Weissberg, J A Ellis, C M Shanahan. J Cell Sci 2001
15
Nesprins: from the nuclear envelope and beyond.
Dipen Rajgor, Catherine M Shanahan. Expert Rev Mol Med 2013
Dipen Rajgor, Catherine M Shanahan. Expert Rev Mol Med 2013
15
Nesprin-2G, a Component of the Nuclear LINC Complex, Is Subject to Myosin-Dependent Tension.
Paul T Arsenovic, Iswarya Ramachandran, Kranthidhar Bathula, Ruijun Zhu, Jiten D Narang, Natalie A Noll, Christopher A Lemmon, Gregg G Gundersen, Daniel E Conway. Biophys J 2016
Paul T Arsenovic, Iswarya Ramachandran, Kranthidhar Bathula, Ruijun Zhu, Jiten D Narang, Natalie A Noll, Christopher A Lemmon, Gregg G Gundersen, Daniel E Conway. Biophys J 2016
15
Nuclear envelope rupture and repair during cancer cell migration.
Celine M Denais, Rachel M Gilbert, Philipp Isermann, Alexandra L McGregor, Mariska te Lindert, Bettina Weigelin, Patricia M Davidson, Peter Friedl, Katarina Wolf, Jan Lammerding. Science 2016
Celine M Denais, Rachel M Gilbert, Philipp Isermann, Alexandra L McGregor, Mariska te Lindert, Bettina Weigelin, Patricia M Davidson, Peter Friedl, Katarina Wolf, Jan Lammerding. Science 2016
14
KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development.
Juehua Yu, Kai Lei, Min Zhou, Cheryl M Craft, Gezhi Xu, Tian Xu, Yuan Zhuang, Rener Xu, Min Han. Hum Mol Genet 2011
Juehua Yu, Kai Lei, Min Zhou, Cheryl M Craft, Gezhi Xu, Tian Xu, Yuan Zhuang, Rener Xu, Min Han. Hum Mol Genet 2011
14
The mammalian LINC complex regulates genome transcriptional responses to substrate rigidity.
Samer G Alam, Qiao Zhang, Nripesh Prasad, Yuan Li, Srikar Chamala, Ram Kuchibhotla, Birendra Kc, Varun Aggarwal, Shristi Shrestha, Angela L Jones,[...]. Sci Rep 2016
Samer G Alam, Qiao Zhang, Nripesh Prasad, Yuan Li, Srikar Chamala, Ram Kuchibhotla, Birendra Kc, Varun Aggarwal, Shristi Shrestha, Angela L Jones,[...]. Sci Rep 2016
20
UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C. elegans development.
C J Malone, W D Fixsen, H R Horvitz, M Han. Development 1999
C J Malone, W D Fixsen, H R Horvitz, M Han. Development 1999
14
Functional association of Sun1 with nuclear pore complexes.
Qian Liu, Nelly Pante, Tom Misteli, Mohamed Elsagga, Melissa Crisp, Didier Hodzic, Brian Burke, Kyle J Roux. J Cell Biol 2007
Qian Liu, Nelly Pante, Tom Misteli, Mohamed Elsagga, Melissa Crisp, Didier Hodzic, Brian Burke, Kyle J Roux. J Cell Biol 2007
14
Nesprin-1 mutations in human and murine cardiomyopathy.
Megan J Puckelwartz, Eric J Kessler, Gene Kim, Megan M Dewitt, Yuan Zhang, Judy U Earley, Frederic F S Depreux, James Holaska, Stephanie K Mewborn, Peter Pytel,[...]. J Mol Cell Cardiol 2010
Megan J Puckelwartz, Eric J Kessler, Gene Kim, Megan M Dewitt, Yuan Zhang, Judy U Earley, Frederic F S Depreux, James Holaska, Stephanie K Mewborn, Peter Pytel,[...]. J Mol Cell Cardiol 2010
13
Lamin A/C deficiency causes defective nuclear mechanics and mechanotransduction.
Jan Lammerding, P Christian Schulze, Tomosaburo Takahashi, Serguei Kozlov, Teresa Sullivan, Roger D Kamm, Colin L Stewart, Richard T Lee. J Clin Invest 2004
Jan Lammerding, P Christian Schulze, Tomosaburo Takahashi, Serguei Kozlov, Teresa Sullivan, Roger D Kamm, Colin L Stewart, Richard T Lee. J Clin Invest 2004
13
Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells.
Meredith H Wilson, Erika L F Holzbaur. Development 2015
Meredith H Wilson, Erika L F Holzbaur. Development 2015
13
Bringing KASH under the SUN: the many faces of nucleo-cytoskeletal connections.
David Razafsky, Didier Hodzic. J Cell Biol 2009
David Razafsky, Didier Hodzic. J Cell Biol 2009
13
Novel nesprin-1 mutations associated with dilated cardiomyopathy cause nuclear envelope disruption and defects in myogenesis.
Can Zhou, Chen Li, Bin Zhou, Huaqin Sun, Victoria Koullourou, Ian Holt, Megan J Puckelwartz, Derek T Warren, Robert Hayward, Ziyuan Lin,[...]. Hum Mol Genet 2017
Can Zhou, Chen Li, Bin Zhou, Huaqin Sun, Victoria Koullourou, Ian Holt, Megan J Puckelwartz, Derek T Warren, Robert Hayward, Ziyuan Lin,[...]. Hum Mol Genet 2017
22
Accumulation of the inner nuclear envelope protein Sun1 is pathogenic in progeric and dystrophic laminopathies.
Chia-Yen Chen, Ya-Hui Chi, Rafidah Abdul Mutalif, Matthew F Starost, Timothy G Myers, Stasia A Anderson, Colin L Stewart, Kuan-Teh Jeang. Cell 2012
Chia-Yen Chen, Ya-Hui Chi, Rafidah Abdul Mutalif, Matthew F Starost, Timothy G Myers, Stasia A Anderson, Colin L Stewart, Kuan-Teh Jeang. Cell 2012
13
Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.
Xiaochang Zhang, Rener Xu, Binggen Zhu, Xiujuan Yang, Xu Ding, Shumin Duan, Tian Xu, Yuan Zhuang, Min Han. Development 2007
Xiaochang Zhang, Rener Xu, Binggen Zhu, Xiujuan Yang, Xu Ding, Shumin Duan, Tian Xu, Yuan Zhuang, Min Han. Development 2007
12
Matrix elasticity directs stem cell lineage specification.
Adam J Engler, Shamik Sen, H Lee Sweeney, Dennis E Discher. Cell 2006
Adam J Engler, Shamik Sen, H Lee Sweeney, Dennis E Discher. Cell 2006
12
Sun2 is a novel mammalian inner nuclear membrane protein.
Didier M Hodzic, David B Yeater, Luiza Bengtsson, Henning Otto, Philip D Stahl. J Biol Chem 2004
Didier M Hodzic, David B Yeater, Luiza Bengtsson, Henning Otto, Philip D Stahl. J Biol Chem 2004
12
Dynamics and molecular interactions of linker of nucleoskeleton and cytoskeleton (LINC) complex proteins.
Cecilia Ostlund, Eric S Folker, Jason C Choi, Edgar R Gomes, Gregg G Gundersen, Howard J Worman. J Cell Sci 2009
Cecilia Ostlund, Eric S Folker, Jason C Choi, Edgar R Gomes, Gregg G Gundersen, Howard J Worman. J Cell Sci 2009
12
Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.
P J Stewart-Hutchinson, Christopher M Hale, Denis Wirtz, Didier Hodzic. Exp Cell Res 2008
P J Stewart-Hutchinson, Christopher M Hale, Denis Wirtz, Didier Hodzic. Exp Cell Res 2008
12
KASHing up with the nucleus: novel functional roles of KASH proteins at the cytoplasmic surface of the nucleus.
G W Gant Luxton, Daniel A Starr. Curr Opin Cell Biol 2014
G W Gant Luxton, Daniel A Starr. Curr Opin Cell Biol 2014
15
Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores.
Alberto Elosegui-Artola, Ion Andreu, Amy E M Beedle, Ainhoa Lezamiz, Marina Uroz, Anita J Kosmalska, Roger Oria, Jenny Z Kechagia, Palma Rico-Lastres, Anabel-Lise Le Roux,[...]. Cell 2017
Alberto Elosegui-Artola, Ion Andreu, Amy E M Beedle, Ainhoa Lezamiz, Marina Uroz, Anita J Kosmalska, Roger Oria, Jenny Z Kechagia, Palma Rico-Lastres, Anabel-Lise Le Roux,[...]. Cell 2017
12
Emerging views of the nucleus as a cellular mechanosensor.
Tyler J Kirby, Jan Lammerding. Nat Cell Biol 2018
Tyler J Kirby, Jan Lammerding. Nat Cell Biol 2018
12
Linker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease.
Matthew J Stroud, Indroneal Banerjee, Jennifer Veevers, Ju Chen. Circ Res 2014
Matthew J Stroud, Indroneal Banerjee, Jennifer Veevers, Ju Chen. Circ Res 2014
18
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.