A citation-based method for searching scientific literature

Konstantin I Piatkov, Christopher S Brower, Alexander Varshavsky. Proc Natl Acad Sci U S A 2012
Times Cited: 98







List of co-cited articles
817 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


The N-end rule pathway and regulation by proteolysis.
Alexander Varshavsky. Protein Sci 2011
436
68

The N-end rule pathway.
Takafumi Tasaki, Shashikanth M Sriram, Kyong Soo Park, Yong Tae Kwon. Annu Rev Biochem 2012
245
60


N-terminal acetylation of cellular proteins creates specific degradation signals.
Cheol-Sang Hwang, Anna Shemorry, Alexander Varshavsky. Science 2010
431
54

Neurodegeneration-associated protein fragments as short-lived substrates of the N-end rule pathway.
Christopher S Brower, Konstantin I Piatkov, Alexander Varshavsky. Mol Cell 2013
78
57

An essential role of N-terminal arginylation in cardiovascular development.
Yong Tae Kwon, Anna S Kashina, Ilia V Davydov, Rong-Gui Hu, Jee Young An, Jai Wha Seo, Fangyong Du, Alexander Varshavsky. Science 2002
243
44

The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators.
Rong-Gui Hu, Jun Sheng, Xin Qi, Zhenming Xu, Terry T Takahashi, Alexander Varshavsky. Nature 2005
222
39

Control of protein quality and stoichiometries by N-terminal acetylation and the N-end rule pathway.
Anna Shemorry, Cheol-Sang Hwang, Alexander Varshavsky. Mol Cell 2013
194
38


Calpain-generated natural protein fragments as short-lived substrates of the N-end rule pathway.
Konstantin I Piatkov, Jang-Hyun Oh, Yuan Liu, Alexander Varshavsky. Proc Natl Acad Sci U S A 2014
58
56

The N-terminal methionine of cellular proteins as a degradation signal.
Heon-Ki Kim, Ryu-Ryun Kim, Jang-Hyun Oh, Hanna Cho, Alexander Varshavsky, Cheol-Sang Hwang. Cell 2014
115
32

RGS4 and RGS5 are in vivo substrates of the N-end rule pathway.
Min Jae Lee, Takafumi Tasaki, Kayoko Moroi, Jee Young An, Sadao Kimura, Ilia V Davydov, Yong Tae Kwon. Proc Natl Acad Sci U S A 2005
181
31

The eukaryotic N-end rule pathway: conserved mechanisms and diverse functions.
Daniel J Gibbs, Jaume Bacardit, Andreas Bachmair, Michael J Holdsworth. Trends Cell Biol 2014
132
29

The N-end rule pathway: from recognition by N-recognins, to destruction by AAA+proteases.
D A Dougan, D Micevski, K N Truscott. Biochim Biophys Acta 2012
84
33

N-degron and C-degron pathways of protein degradation.
Alexander Varshavsky. Proc Natl Acad Sci U S A 2019
204
27

Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding.
Hyunjoo Cha-Molstad, Ki Sa Sung, Joonsung Hwang, Kyoung A Kim, Ji Eun Yu, Young Dong Yoo, Jun Min Jang, Dong Hoon Han, Michael Molstad, Jung Gi Kim,[...]. Nat Cell Biol 2015
138
26

The auto-generated fragment of the Usp1 deubiquitylase is a physiological substrate of the N-end rule pathway.
Konstantin I Piatkov, Luca Colnaghi, Miklos Békés, Alexander Varshavsky, Tony T Huang. Mol Cell 2012
50
50

Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases.
Woo Suk Choi, Byung-Cheon Jeong, Yoo Jin Joo, Myeong-Ryeol Lee, Joon Kim, Michael J Eck, Hyun Kyu Song. Nat Struct Mol Biol 2010
97
25

An N-end rule pathway that recognizes proline and destroys gluconeogenic enzymes.
Shun-Jia Chen, Xia Wu, Brandon Wadas, Jang-Hyun Oh, Alexander Varshavsky. Science 2017
105
25

The degradation signal in a short-lived protein.
A Bachmair, A Varshavsky. Cell 1989
355
22

Structural basis of substrate recognition and specificity in the N-end rule pathway.
Edna Matta-Camacho, Guennadi Kozlov, Flora F Li, Kalle Gehring. Nat Struct Mol Biol 2010
74
29

Glutamine-specific N-terminal amidase, a component of the N-end rule pathway.
Haiqing Wang, Konstantin I Piatkov, Christopher S Brower, Alexander Varshavsky. Mol Cell 2009
64
32


The N-end rule in bacteria.
J W Tobias, T E Shrader, G Rocap, A Varshavsky. Science 1991
420
21

Oxygen sensing in plants is mediated by an N-end rule pathway for protein destabilization.
Francesco Licausi, Monika Kosmacz, Daan A Weits, Beatrice Giuntoli, Federico M Giorgi, Laurentius A C J Voesenek, Pierdomenico Perata, Joost T van Dongen. Nature 2011
389
19

Homeostatic response to hypoxia is regulated by the N-end rule pathway in plants.
Daniel J Gibbs, Seung Cho Lee, Nurulhikma Md Isa, Silvia Gramuglia, Takeshi Fukao, George W Bassel, Cristina Sousa Correia, Françoise Corbineau, Frederica L Theodoulou, Julia Bailey-Serres,[...]. Nature 2011
372
19

Control of mammalian G protein signaling by N-terminal acetylation and the N-end rule pathway.
Sang-Eun Park, Jeong-Mok Kim, Ok-Hee Seok, Hanna Cho, Brandon Wadas, Seon-Young Kim, Alexander Varshavsky, Cheol-Sang Hwang. Science 2015
88
21

The N-end rule pathway for regulated proteolysis: prokaryotic and eukaryotic strategies.
Axel Mogk, Ronny Schmidt, Bernd Bukau. Trends Cell Biol 2007
189
18

The N-end rule pathway is a sensor of heme.
Rong-Gui Hu, Haiqing Wang, Zanxian Xia, Alexander Varshavsky. Proc Natl Acad Sci U S A 2008
87
20


The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases.
Cheol-Sang Hwang, Anna Shemorry, Daniel Auerbach, Alexander Varshavsky. Nat Cell Biol 2010
101
17


Degradation of DIAP1 by the N-end rule pathway is essential for regulating apoptosis.
Mark Ditzel, Rebecca Wilson, Tencho Tenev, Anna Zachariou, Angela Paul, Emma Deas, Pascal Meier. Nat Cell Biol 2003
199
17

Analyzing N-terminal Arginylation through the Use of Peptide Arrays and Degradation Assays.
Brandon Wadas, Konstantin I Piatkov, Christopher S Brower, Alexander Varshavsky. J Biol Chem 2016
20
85

Discovery of cellular regulation by protein degradation.
Alexander Varshavsky. J Biol Chem 2008
73
21

The plant N-end rule pathway: structure and functions.
Emmanuelle Graciet, Frank Wellmer. Trends Plant Sci 2010
67
23

Ubiquitin fusion technique and related methods.
Alexander Varshavsky. Methods Enzymol 2005
83
19

The ubiquitin-proteasome system of Saccharomyces cerevisiae.
Daniel Finley, Helle D Ulrich, Thomas Sommer, Peter Kaiser. Genetics 2012
256
16

A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons.
Takafumi Tasaki, Lubbertus C F Mulder, Akihiro Iwamatsu, Min Jae Lee, Ilia V Davydov, Alexander Varshavsky, Mark Muesing, Yong Tae Kwon. Mol Cell Biol 2005
229
16


Protein N-terminal acetyltransferases: when the start matters.
Kristian K Starheim, Kris Gevaert, Thomas Arnesen. Trends Biochem Sci 2012
194
15

Aminoacyl-transferases and the N-end rule pathway of prokaryotic/eukaryotic specificity in a human pathogen.
Emmanuelle Graciet, Rong-Gui Hu, Konstantin Piatkov, Joon Haeng Rhee, Erich M Schwarz, Alexander Varshavsky. Proc Natl Acad Sci U S A 2006
71
21

Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome).
Martin Zenker, Julia Mayerle, Markus M Lerch, Andreas Tagariello, Klaus Zerres, Peter R Durie, Matthias Beier, Georg Hülskamp, Celina Guzman, Helga Rehder,[...]. Nat Genet 2005
172
15

PINK1 is degraded through the N-end rule pathway.
Koji Yamano, Richard J Youle. Autophagy 2013
365
15

Global analysis of posttranslational protein arginylation.
Catherine C L Wong, Tao Xu, Reena Rai, Aaron O Bailey, John R Yates, Yuri I Wolf, Henry Zebroski, Anna Kashina. PLoS Biol 2007
99
15


Universality and structure of the N-end rule.
D K Gonda, A Bachmair, I Wünning, J W Tobias, W S Lane, A Varshavsky. J Biol Chem 1989
363
14

Protein N-terminal processing: substrate specificity of Escherichia coli and human methionine aminopeptidases.
Qing Xiao, Feiran Zhang, Benjamin A Nacev, Jun O Liu, Dehua Pei. Biochemistry 2010
107
14

Characterization of arginylation branch of N-end rule pathway in G-protein-mediated proliferation and signaling of cardiomyocytes.
Min Jae Lee, Dong Eun Kim, Adriana Zakrzewska, Young Dong Yoo, Su-Hyeon Kim, Sung Tae Kim, Jai Wha Seo, Young Sook Lee, Gerald W Dorn, Uhtaek Oh,[...]. J Biol Chem 2012
37
37

The N-end rule pathway: emerging functions and molecular principles of substrate recognition.
Shashikanth M Sriram, Bo Yeon Kim, Yong Tae Kwon. Nat Rev Mol Cell Biol 2011
130
14


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.