Susan M E Smith, Jaeki Min, Thota Ganesh, Becky Diebold, Tsukasa Kawahara, Yerun Zhu, James McCoy, Aiming Sun, James P Snyder, Haian Fu, Yuhong Du, Iestyn Lewis, J David Lambeth. Chem Biol 2012
Times Cited: 67
Times Cited: 67
Times Cited
Times Co-cited
Similarity
The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology.
Karen Bedard, Karl-Heinz Krause. Physiol Rev 2007
Karen Bedard, Karl-Heinz Krause. Physiol Rev 2007
52
Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant.
Sabine Heumüller, Sven Wind, Eduardo Barbosa-Sicard, Harald H H W Schmidt, Rudi Busse, Katrin Schröder, Ralf P Brandes. Hypertension 2008
Sabine Heumüller, Sven Wind, Eduardo Barbosa-Sicard, Harald H H W Schmidt, Rudi Busse, Katrin Schröder, Ralf P Brandes. Hypertension 2008
34
NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action.
Vincent Jaquet, Julien Marcoux, Eric Forest, Kevin G Leidal, Sally McCormick, Yvonne Westermaier, Remo Perozzo, Olivier Plastre, Laetitia Fioraso-Cartier, Becky Diebold,[...]. Br J Pharmacol 2011
Vincent Jaquet, Julien Marcoux, Eric Forest, Kevin G Leidal, Sally McCormick, Yvonne Westermaier, Remo Perozzo, Olivier Plastre, Laetitia Fioraso-Cartier, Becky Diebold,[...]. Br J Pharmacol 2011
34
Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O(2)(-) and systolic blood pressure in mice.
F E Rey, M E Cifuentes, A Kiarash, M T Quinn, P J Pagano. Circ Res 2001
F E Rey, M E Cifuentes, A Kiarash, M T Quinn, P J Pagano. Circ Res 2001
29
A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells.
Davide Gianni, Nicolas Taulet, Hui Zhang, Celine DerMardirossian, Jeremy Kister, Luis Martinez, William R Roush, Steven J Brown, Gary M Bokoch, Hugh Rosen. ACS Chem Biol 2010
Davide Gianni, Nicolas Taulet, Hui Zhang, Celine DerMardirossian, Jeremy Kister, Luis Martinez, William R Roush, Steven J Brown, Gary M Bokoch, Hugh Rosen. ACS Chem Biol 2010
26
Small-molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets.
Vincent Jaquet, Leonardo Scapozza, Robert A Clark, Karl-Heinz Krause, J David Lambeth. Antioxid Redox Signal 2009
Vincent Jaquet, Leonardo Scapozza, Robert A Clark, Karl-Heinz Krause, J David Lambeth. Antioxid Redox Signal 2009
25
First in class, potent, and orally bioavailable NADPH oxidase isoform 4 (Nox4) inhibitors for the treatment of idiopathic pulmonary fibrosis.
Benoît Laleu, Francesca Gaggini, Mike Orchard, Laetitia Fioraso-Cartier, Laurène Cagnon, Sophie Houngninou-Molango, Angelo Gradia, Guillaume Duboux, Cédric Merlot, Freddy Heitz,[...]. J Med Chem 2010
Benoît Laleu, Francesca Gaggini, Mike Orchard, Laetitia Fioraso-Cartier, Laurène Cagnon, Sophie Houngninou-Molango, Angelo Gradia, Guillaume Duboux, Cédric Merlot, Freddy Heitz,[...]. J Med Chem 2010
25
Nox2 B-loop peptide, Nox2ds, specifically inhibits the NADPH oxidase Nox2.
Gábor Csányi, Eugenia Cifuentes-Pagano, Imad Al Ghouleh, Daniel J Ranayhossaini, Loreto Egaña, Lucia R Lopes, Heather M Jackson, Eric E Kelley, Patrick J Pagano. Free Radic Biol Med 2011
Gábor Csányi, Eugenia Cifuentes-Pagano, Imad Al Ghouleh, Daniel J Ranayhossaini, Loreto Egaña, Lucia R Lopes, Heather M Jackson, Eric E Kelley, Patrick J Pagano. Free Radic Biol Med 2011
25
Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferation.
Henrik ten Freyhaus, Michael Huntgeburth, Kirstin Wingler, Jessika Schnitker, Anselm T Bäumer, Marius Vantler, Mohamed M Bekhite, Maria Wartenberg, Heinrich Sauer, Stephan Rosenkranz. Cardiovasc Res 2006
Henrik ten Freyhaus, Michael Huntgeburth, Kirstin Wingler, Jessika Schnitker, Anselm T Bäumer, Marius Vantler, Mohamed M Bekhite, Maria Wartenberg, Heinrich Sauer, Stephan Rosenkranz. Cardiovasc Res 2006
23
The NOX toolbox: validating the role of NADPH oxidases in physiology and disease.
Sebastian Altenhöfer, Pamela W M Kleikers, Kim A Radermacher, Peter Scheurer, J J Rob Hermans, Paul Schiffers, Heidi Ho, Kirstin Wingler, Harald H H W Schmidt. Cell Mol Life Sci 2012
Sebastian Altenhöfer, Pamela W M Kleikers, Kim A Radermacher, Peter Scheurer, J J Rob Hermans, Paul Schiffers, Heidi Ho, Kirstin Wingler, Harald H H W Schmidt. Cell Mol Life Sci 2012
20
Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets.
Grant R Drummond, Stavros Selemidis, Kathy K Griendling, Christopher G Sobey. Nat Rev Drug Discov 2011
Grant R Drummond, Stavros Selemidis, Kathy K Griendling, Christopher G Sobey. Nat Rev Drug Discov 2011
19
Comparative pharmacology of chemically distinct NADPH oxidase inhibitors.
S Wind, K Beuerlein, T Eucker, H Müller, P Scheurer, M E Armitage, H Ho, H H H W Schmidt, K Wingler. Br J Pharmacol 2010
S Wind, K Beuerlein, T Eucker, H Müller, P Scheurer, M E Armitage, H Ho, H H H W Schmidt, K Wingler. Br J Pharmacol 2010
19
Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement.
Sebastian Altenhöfer, Kim A Radermacher, Pamela W M Kleikers, Kirstin Wingler, Harald H H W Schmidt. Antioxid Redox Signal 2015
Sebastian Altenhöfer, Kim A Radermacher, Pamela W M Kleikers, Kirstin Wingler, Harald H H W Schmidt. Antioxid Redox Signal 2015
19
Fulvene-5 potently inhibits NADPH oxidase 4 and blocks the growth of endothelial tumors in mice.
Sulochana S Bhandarkar, Marisa Jaconi, Levi E Fried, Michael Y Bonner, Benjamin Lefkove, Baskaran Govindarajan, Betsy N Perry, Ravi Parhar, Jamie Mackelfresh, Allie Sohn,[...]. J Clin Invest 2009
Sulochana S Bhandarkar, Marisa Jaconi, Levi E Fried, Michael Y Bonner, Benjamin Lefkove, Baskaran Govindarajan, Betsy N Perry, Ravi Parhar, Jamie Mackelfresh, Allie Sohn,[...]. J Clin Invest 2009
17
NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation.
Lena Serrander, Laetitia Cartier, Karen Bedard, Botond Banfi, Bernard Lardy, Olivier Plastre, Andrzej Sienkiewicz, Lászlo Fórró, Werner Schlegel, Karl-Heinz Krause. Biochem J 2007
Lena Serrander, Laetitia Cartier, Karen Bedard, Botond Banfi, Bernard Lardy, Olivier Plastre, Andrzej Sienkiewicz, Lászlo Fórró, Werner Schlegel, Karl-Heinz Krause. Biochem J 2007
16
Activation and assembly of the NADPH oxidase: a structural perspective.
Yvonne Groemping, Katrin Rittinger. Biochem J 2005
Yvonne Groemping, Katrin Rittinger. Biochem J 2005
16
Off-target thiol alkylation by the NADPH oxidase inhibitor 3-benzyl-7-(2-benzoxazolyl)thio-1,2,3-triazolo[4,5-d]pyrimidine (VAS2870).
Qi-An Sun, Douglas T Hess, Benlian Wang, Masaru Miyagi, Jonathan S Stamler. Free Radic Biol Med 2012
Qi-An Sun, Douglas T Hess, Benlian Wang, Masaru Miyagi, Jonathan S Stamler. Free Radic Biol Med 2012
19
NADPH oxidase-dependent and -independent mechanisms of reported inhibitors of reactive oxygen generation.
Gregory J Gatto, Zhaohui Ao, Michael G Kearse, Mei Zhou, Cyndi R Morales, Erin Daniels, Benjamin T Bradley, Matthew T Goserud, Krista B Goodman, Stephen A Douglas,[...]. J Enzyme Inhib Med Chem 2013
Gregory J Gatto, Zhaohui Ao, Michael G Kearse, Mei Zhou, Cyndi R Morales, Erin Daniels, Benjamin T Bradley, Matthew T Goserud, Krista B Goodman, Stephen A Douglas,[...]. J Enzyme Inhib Med Chem 2013
21
Ebselen in acute ischemic stroke: a placebo-controlled, double-blind clinical trial. Ebselen Study Group.
T Yamaguchi, K Sano, K Takakura, I Saito, Y Shinohara, T Asano, H Yasuhara. Stroke 1998
T Yamaguchi, K Sano, K Takakura, I Saito, Y Shinohara, T Asano, H Yasuhara. Stroke 1998
16
Selective recapitulation of conserved and nonconserved regions of putative NOXA1 protein activation domain confers isoform-specific inhibition of Nox1 oxidase and attenuation of endothelial cell migration.
Daniel J Ranayhossaini, Andres I Rodriguez, Sanghamitra Sahoo, Beibei B Chen, Rama K Mallampalli, Eric E Kelley, Gabor Csanyi, Mark T Gladwin, Guillermo Romero, Patrick J Pagano. J Biol Chem 2013
Daniel J Ranayhossaini, Andres I Rodriguez, Sanghamitra Sahoo, Beibei B Chen, Rama K Mallampalli, Eric E Kelley, Gabor Csanyi, Mark T Gladwin, Guillermo Romero, Patrick J Pagano. J Biol Chem 2013
19
Discovery of GSK2795039, a Novel Small Molecule NADPH Oxidase 2 Inhibitor.
Kazufumi Hirano, Woei Shin Chen, Adeline L W Chueng, Angela A Dunne, Tamara Seredenina, Aleksandra Filippova, Sumitra Ramachandran, Angela Bridges, Laiq Chaudry, Gary Pettman,[...]. Antioxid Redox Signal 2015
Kazufumi Hirano, Woei Shin Chen, Adeline L W Chueng, Angela A Dunne, Tamara Seredenina, Aleksandra Filippova, Sumitra Ramachandran, Angela Bridges, Laiq Chaudry, Gary Pettman,[...]. Antioxid Redox Signal 2015
16
Design, synthesis and biological activity of original pyrazolo-pyrido-diazepine, -pyrazine and -oxazine dione derivatives as novel dual Nox4/Nox1 inhibitors.
Francesca Gaggini, Benoît Laleu, Mike Orchard, Laetitia Fioraso-Cartier, Laurène Cagnon, Sophie Houngninou-Molango, Angelo Gradia, Guillaume Duboux, Cédric Merlot, Freddy Heitz,[...]. Bioorg Med Chem 2011
Francesca Gaggini, Benoît Laleu, Mike Orchard, Laetitia Fioraso-Cartier, Laurène Cagnon, Sophie Houngninou-Molango, Angelo Gradia, Guillaume Duboux, Cédric Merlot, Freddy Heitz,[...]. Bioorg Med Chem 2011
16
Molecular basis of phosphorylation-induced activation of the NADPH oxidase.
Yvonne Groemping, Karine Lapouge, Stephen J Smerdon, Katrin Rittinger. Cell 2003
Yvonne Groemping, Karine Lapouge, Stephen J Smerdon, Katrin Rittinger. Cell 2003
14
Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent.
Tomonori Aoyama, Yong-Han Paik, Sumio Watanabe, Benoît Laleu, Francesca Gaggini, Laetitia Fioraso-Cartier, Sophie Molango, Freddy Heitz, Cédric Merlot, Cédric Szyndralewiez,[...]. Hepatology 2012
Tomonori Aoyama, Yong-Han Paik, Sumio Watanabe, Benoît Laleu, Francesca Gaggini, Laetitia Fioraso-Cartier, Sophie Molango, Freddy Heitz, Cédric Merlot, Cédric Szyndralewiez,[...]. Hepatology 2012
14
Poldip2, a novel regulator of Nox4 and cytoskeletal integrity in vascular smooth muscle cells.
Alicia N Lyle, Nita N Deshpande, Yoshihiro Taniyama, Bonnie Seidel-Rogol, Lily Pounkova, Pingfeng Du, Christopher Papaharalambus, Bernard Lassègue, Kathy K Griendling. Circ Res 2009
Alicia N Lyle, Nita N Deshpande, Yoshihiro Taniyama, Bonnie Seidel-Rogol, Lily Pounkova, Pingfeng Du, Christopher Papaharalambus, Bernard Lassègue, Kathy K Griendling. Circ Res 2009
14
NADPH oxidase inhibitors: a decade of discovery from Nox2ds to HTS.
Eugenia Cifuentes-Pagano, Gabor Csanyi, Patrick J Pagano. Cell Mol Life Sci 2012
Eugenia Cifuentes-Pagano, Gabor Csanyi, Patrick J Pagano. Cell Mol Life Sci 2012
14
14
A novel biologically active seleno-organic compound--I. Glutathione peroxidase-like activity in vitro and antioxidant capacity of PZ 51 (Ebselen).
A Müller, E Cadenas, P Graf, H Sies. Biochem Pharmacol 1984
A Müller, E Cadenas, P Graf, H Sies. Biochem Pharmacol 1984
13
A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes.
B Bánfi, G Molnár, A Maturana, K Steger, B Hegedûs, N Demaurex, K H Krause. J Biol Chem 2001
B Bánfi, G Molnár, A Maturana, K Steger, B Hegedûs, N Demaurex, K H Krause. J Biol Chem 2001
13
Inhibition of NADPH oxidase activation by 4-(2-aminoethyl)-benzenesulfonyl fluoride and related compounds.
V Diatchuk, O Lotan, V Koshkin, P Wikstroem, E Pick. J Biol Chem 1997
V Diatchuk, O Lotan, V Koshkin, P Wikstroem, E Pick. J Biol Chem 1997
13
The E-loop is involved in hydrogen peroxide formation by the NADPH oxidase Nox4.
Ina Takac, Katrin Schröder, Leilei Zhang, Bernard Lardy, Narayana Anilkumar, J David Lambeth, Ajay M Shah, Francoise Morel, Ralf P Brandes. J Biol Chem 2011
Ina Takac, Katrin Schröder, Leilei Zhang, Bernard Lardy, Narayana Anilkumar, J David Lambeth, Ajay M Shah, Francoise Morel, Ralf P Brandes. J Biol Chem 2011
13
Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system.
Bernard Lassègue, Alejandra San Martín, Kathy K Griendling. Circ Res 2012
Bernard Lassègue, Alejandra San Martín, Kathy K Griendling. Circ Res 2012
13
Nox3 regulation by NOXO1, p47phox, and p67phox.
Guangjie Cheng, Darren Ritsick, J David Lambeth. J Biol Chem 2004
Guangjie Cheng, Darren Ritsick, J David Lambeth. J Biol Chem 2004
13
Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5.
G Cheng, Z Cao, X Xu, E G van Meir, J D Lambeth. Gene 2001
G Cheng, Z Cao, X Xu, E G van Meir, J D Lambeth. Gene 2001
13
Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase.
Rashmi K Ambasta, Pravir Kumar, Kathy K Griendling, Harald H H W Schmidt, Rudi Busse, Ralf P Brandes. J Biol Chem 2004
Rashmi K Ambasta, Pravir Kumar, Kathy K Griendling, Harald H H W Schmidt, Rudi Busse, Ralf P Brandes. J Biol Chem 2004
13
Two novel proteins activate superoxide generation by the NADPH oxidase NOX1.
Botond Bánfi, Robert A Clark, Klaus Steger, Karl-Heinz Krause. J Biol Chem 2003
Botond Bánfi, Robert A Clark, Klaus Steger, Karl-Heinz Krause. J Biol Chem 2003
11
Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration.
Christoph Kleinschnitz, Henrike Grund, Kirstin Wingler, Melanie E Armitage, Emma Jones, Manish Mittal, David Barit, Tobias Schwarz, Christian Geis, Peter Kraft,[...]. PLoS Biol 2010
Christoph Kleinschnitz, Henrike Grund, Kirstin Wingler, Melanie E Armitage, Emma Jones, Manish Mittal, David Barit, Tobias Schwarz, Christian Geis, Peter Kraft,[...]. PLoS Biol 2010
11
S17834, a new inhibitor of cell adhesion and atherosclerosis that targets nadph oxidase.
A J Cayatte, A Rupin, J Oliver-Krasinski, K Maitland, P Sansilvestri-Morel, M F Boussard, M Wierzbicki, T J Verbeuren, R A Cohen. Arterioscler Thromb Vasc Biol 2001
A J Cayatte, A Rupin, J Oliver-Krasinski, K Maitland, P Sansilvestri-Morel, M F Boussard, M Wierzbicki, T J Verbeuren, R A Cohen. Arterioscler Thromb Vasc Biol 2001
11
Studies on the inhibitory mechanism of iodonium compounds with special reference to neutrophil NADPH oxidase.
B V O'Donnell, D G Tew, O T Jones, P J England. Biochem J 1993
B V O'Donnell, D G Tew, O T Jones, P J England. Biochem J 1993
11
Novel Nox inhibitor of oxLDL-induced reactive oxygen species formation in human endothelial cells.
Claudia Stielow, Rusan A Catar, Gregor Muller, Kirstin Wingler, Peter Scheurer, Harald H H W Schmidt, Henning Morawietz. Biochem Biophys Res Commun 2006
Claudia Stielow, Rusan A Catar, Gregor Muller, Kirstin Wingler, Peter Scheurer, Harald H H W Schmidt, Henning Morawietz. Biochem Biophys Res Commun 2006
11
Novel NAD(P)H oxidase inhibitor suppresses angioplasty-induced superoxide and neointimal hyperplasia of rat carotid artery.
Gary M Jacobson, Hector M Dourron, Jianhua Liu, Oscar A Carretero, Daniel J Reddy, Tanja Andrzejewski, Patrick J Pagano. Circ Res 2003
Gary M Jacobson, Hector M Dourron, Jianhua Liu, Oscar A Carretero, Daniel J Reddy, Tanja Andrzejewski, Patrick J Pagano. Circ Res 2003
11
Bridged tetrahydroisoquinolines as selective NADPH oxidase 2 (Nox2) inhibitors.
Eugenia Cifuentes-Pagano, Jaideep Saha, Gábor Csányi, Imad Al Ghouleh, Sanghamitra Sahoo, Andrés Rodríguez, Peter Wipf, Patrick J Pagano, Erin M Skoda. Medchemcomm 2013
Eugenia Cifuentes-Pagano, Jaideep Saha, Gábor Csányi, Imad Al Ghouleh, Sanghamitra Sahoo, Andrés Rodríguez, Peter Wipf, Patrick J Pagano, Erin M Skoda. Medchemcomm 2013
42
The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators.
Noriko Ueno, Ryu Takeya, Kei Miyano, Hideaki Kikuchi, Hideki Sumimoto. J Biol Chem 2005
Noriko Ueno, Ryu Takeya, Kei Miyano, Hideaki Kikuchi, Hideki Sumimoto. J Biol Chem 2005
11
NADPH oxidase 1 plays a key role in diabetes mellitus-accelerated atherosclerosis.
Stephen P Gray, Elyse Di Marco, Jun Okabe, Cedric Szyndralewiez, Freddy Heitz, Augusto C Montezano, Judy B de Haan, Christine Koulis, Assam El-Osta, Karen L Andrews,[...]. Circulation 2013
Stephen P Gray, Elyse Di Marco, Jun Okabe, Cedric Szyndralewiez, Freddy Heitz, Augusto C Montezano, Judy B de Haan, Christine Koulis, Assam El-Osta, Karen L Andrews,[...]. Circulation 2013
11
NOX5: from basic biology to signaling and disease.
Karen Bedard, Vincent Jaquet, Karl-Heinz Krause. Free Radic Biol Med 2012
Karen Bedard, Vincent Jaquet, Karl-Heinz Krause. Free Radic Biol Med 2012
11
Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species.
Hideki Sumimoto. FEBS J 2008
Hideki Sumimoto. FEBS J 2008
11
Studies on the anti-inflammatory activity of ebselen. Ebselen interferes with granulocyte oxidative burst by dual inhibition of NADPH oxidase and protein kinase C?
I A Cotgreave, S K Duddy, G E Kass, D Thompson, P Moldéus. Biochem Pharmacol 1989
I A Cotgreave, S K Duddy, G E Kass, D Thompson, P Moldéus. Biochem Pharmacol 1989
10
Mechanism of Ca2+ activation of the NADPH oxidase 5 (NOX5).
Botond Bánfi, Fabiana Tirone, Isabelle Durussel, Judit Knisz, Patryk Moskwa, Gergely Zoltán Molnár, Karl-Heinz Krause, Jos A Cox. J Biol Chem 2004
Botond Bánfi, Fabiana Tirone, Isabelle Durussel, Judit Knisz, Patryk Moskwa, Gergely Zoltán Molnár, Karl-Heinz Krause, Jos A Cox. J Biol Chem 2004
10
Inhibition of endothelial nitric oxide synthase by ebselen. Prevention by thiols suggests the inactivation by ebselen of a critical thiol essential for the catalytic activity of nitric oxide synthase.
A Zembowicz, R J Hatchett, W Radziszewski, R J Gryglewski. J Pharmacol Exp Ther 1993
A Zembowicz, R J Hatchett, W Radziszewski, R J Gryglewski. J Pharmacol Exp Ther 1993
10
Ebselen, a selenoorganic compound as glutathione peroxidase mimic.
H Sies. Free Radic Biol Med 1993
H Sies. Free Radic Biol Med 1993
10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.